Journal of Shahid Sadoughi University of Medical Sciences最新文献

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Platelet Therapy and Ovarian Rejuvenation in Women with Premature Ovarian Failure 卵巢早衰妇女的血小板治疗和卵巢年轻化

Journal of Shahid Sadoughi University of Medical Sciences Pub Date : 2023-09-26 DOI: 10.18502/ssu.v31i7.13691

Marzieh Lotfi, Leila Azod, Malihe Lotfi, Fatemeh Tohidi, Seyed Hossein Shahcheraghi

引用次数: 0

Effect of Eight Weeks of Resistance Training on Inflammatory Markers and Antioxidant Indices of Kidney Tissue Following Testosterone Enanthate Abuse in Male Rats 8周抗阻训练对雄性大鼠滥用睾酮后肾脏组织炎症指标和抗氧化指标的影响

Journal of Shahid Sadoughi University of Medical Sciences Pub Date : 2023-09-26 DOI: 10.18502/ssu.v31i7.13698

Masoumeh Mehrabi, Yaser Kazemzadeh, Ali Gorzi, Seyed Ali Hosseini, Saeid Sedaghati

{"title":"Effect of Eight Weeks of Resistance Training on Inflammatory Markers and Antioxidant Indices of Kidney Tissue Following Testosterone Enanthate Abuse in Male Rats","authors":"Masoumeh Mehrabi, Yaser Kazemzadeh, Ali Gorzi, Seyed Ali Hosseini, Saeid Sedaghati","doi":"10.18502/ssu.v31i7.13698","DOIUrl":"https://doi.org/10.18502/ssu.v31i7.13698","url":null,"abstract":"Introduction: Abuse of anabolic steroids can lead to kidney tissue damage.The aim of this study was to investigate the effect of eight weeks of resistance training on inflammatory markers and antioxidant indices of kidney tissue of male rats following testosterone enanthate abuse. Methods: In this experimental study, 24 male Wistar rats were randomly divided into three groups: 1) Control, 2) Training and 3) Training + Testosterone. Rats in groups 2 and 3 performed resistance training five sessions a week for eight weeks. Moreover, group 3 received 20 mg/kg of testosterone enanthate intramuscularly three days a week. The activity levels of Superoxide dismutase (SOD) and Glutathione peroxidase (GPx) were measured by spectrophotometric method and the gene expression of Interleukin-6 (IL-6) and Tumor necrosis factor alpha (TNF-α) were measured by Real Time PCR method. The data were analyzed using SPSS version 16 software. To analyze the findings, To analyze the findings, one-way analysis of variance was used (P≥0.05). Results: Resistance training caused a significant decrease in GPx activity (P=0.001) compared to the control group. IL-6 gene expression in the training + testosterone group was significantly more than the training group (P=0.04) and the control group (P=0.001). Training + testosterone caused a significant increase in TNF-α gene expression compared to the training group (P=0.02) and the control group (P=0.008). Furthermore, the level of GPx activity in the training + testosterone group was significantly lower than the control group (P=0.001), but no significant difference was observed in the training + testosterone groups and the training group (P=0.93). Conclusion: It seems that testosterone abuse along with intense resistance training is associated with a decrease in the function of the antioxidant system and increase in inflammatory markers in the kidney tissue.","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134960129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychometric Properties of Persian Version of the Ottawa Self-Injury Inventory in Hospitalized Patients 住院病人渥太华自伤量表波斯语版的心理测量特征

Journal of Shahid Sadoughi University of Medical Sciences Pub Date : 2023-08-27 DOI: 10.18502/ssu.v31i6.13477

Akbari Valiollah, Mostafa Vahedian, Parvin Rahmatinejad

{"title":"Psychometric Properties of Persian Version of the Ottawa Self-Injury Inventory in Hospitalized Patients","authors":"Akbari Valiollah, Mostafa Vahedian, Parvin Rahmatinejad","doi":"10.18502/ssu.v31i6.13477","DOIUrl":"https://doi.org/10.18502/ssu.v31i6.13477","url":null,"abstract":"Introduction: Non-Suicidal Self-Injury (NSSI) has high prevalence among the patients with psychiatric disorders. Self-Injury plays an important role in the treatment, prognosis and risk of suicide, which highlights the need for an appropriate tool to assess the nature and psychological functions of NSSI. Therefore, the aim of this study was to determine the psychometric properties of the Persian version of the Ottawa Self-Injury inventory (OSI) in hospitalized patients. Methods: The present study was a psychometric study based on analytical method. The research has been performed on 310 patients with non-suicidal self-injury who have been referred to Nekoei-Hedayati Hospital in Qom City. Sample group completed Persian version of the Ottawa Self-Injury inventory. Data were analyzed using SPSS-16 and Cronbach’s alpha coefficient, Content Validity Index (CVI) and Content Validity Ratio (CVR). Results: The results showed that content validity index in this study was more than 0.75 and content validity ratio for validity of questions was more than 0.79. The impact score of all items (Except for the tenth question) was higher than 1.5 that confirmed the face validity of inventory. The total Cronbach's alpha coefficient was calculated 0.71. Another result of this study was that 52% of patients reported at least one addictive characteristic. Conclusion: The finding showed that Persian version of Ottawa Self-Injury inventory has appropriate validity (face /content) and reliability in the inpatient population","PeriodicalId":17084,"journal":{"name":"Journal of Shahid Sadoughi University of Medical Sciences","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135138842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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