Journal of Surfactants and Detergents最新文献

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Performance and mildness of alkyl glycoside hydroxypropyl sulfonate 烷基糖苷羟丙基磺酸盐的性能和温和性
IF 1.6 4区 工程技术
Journal of Surfactants and Detergents Pub Date : 2024-06-27 DOI: 10.1002/jsde.12781
Kuan Chang, Baotong Jia
{"title":"Performance and mildness of alkyl glycoside hydroxypropyl sulfonate","authors":"Kuan Chang,&nbsp;Baotong Jia","doi":"10.1002/jsde.12781","DOIUrl":"10.1002/jsde.12781","url":null,"abstract":"<p>Alkyl glycoside hydroxypropyl sulfonate (APGSHS), as a kind of anionic surfactant was successfully prepared using sodium 3-chloro-2-hydroxypropane sulfonate and alkyl polyglucoside (APG). The surface and application properties of APGSHS were studied in detail. The results showed that APGSHS showed much enhanced solubility and there for better foaming and detergency properties than APG due to the introduction of sulfonate group. Then, the mildness of APGSHS and commercially available mild surfactants was compared using zein test and hemolysis of red blood cells (RBC) test. APGSHS has higher mildness than other surfactants, such as potassium lauroylglycinate (PLG), lauramidopropyl betaine (LAB), and sodium laurylmethyl taurate (LMT). The mechanism of mildness was investigated by studying the interaction between APGSHS and protein using zein model through micelle behavior and protein structure. It was observed that compared to other anionic surfactants such as sodium fatty alcohol polyoxyethylene ether sulfate (AES) and sodium dodecyl sulfate (SDS), APGSHS possesses a larger hydrophilic head group and causes less damage to the secondary structure of zein. Finally, the effect of different surfactants on the hair keratin loss during washing was evaluated. The results showed APGSHS had a minimal damaging effect on keratin in the hair, resulting in the lowest protein loss. This work suggests APGSHS as a promising ingredient for green and mild cleaning products.</p>","PeriodicalId":17083,"journal":{"name":"Journal of Surfactants and Detergents","volume":"28 1","pages":"85-96"},"PeriodicalIF":1.6,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141509924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The interfacial properties of biosurfactant mixtures 生物表面活性剂混合物的界面特性
IF 1.6 4区 工程技术
Journal of Surfactants and Detergents Pub Date : 2024-06-14 DOI: 10.1002/jsde.12777
Janet R. McMillan, Daniel S. Miller, Caroline Nimako-Boateng, Lauren Wilson, Tzu-Chi Kuo, Micol Frederica Tesoldi, Timothy Young, Aslin Izmitli
{"title":"The interfacial properties of biosurfactant mixtures","authors":"Janet R. McMillan,&nbsp;Daniel S. Miller,&nbsp;Caroline Nimako-Boateng,&nbsp;Lauren Wilson,&nbsp;Tzu-Chi Kuo,&nbsp;Micol Frederica Tesoldi,&nbsp;Timothy Young,&nbsp;Aslin Izmitli","doi":"10.1002/jsde.12777","DOIUrl":"10.1002/jsde.12777","url":null,"abstract":"<p>There is growing global demand to transition to more sustainable surfactant technologies. Towards this vision, bio-based surfactants and biosurfactants are being explored as alternatives to traditional petrochemical surfactants. However, the transition towards these technologies is expected to be gradual, therefore there is a critical need to formulate new biosurfactants in combination with traditional surfactant classes such as alkoxylates, sulfates and amine-oxides to achieve a balance of performance, cost, and sustainability. To this end, we report a study of the impact of sophorolipid biosurfactants on the cloud point of alcohol ethoxylates, and on the surface tension and foaming of alkyl sulfate/amine-oxide mixtures. We make the surprising finding that high-acid sophorolipids can act as highly efficient hydrotropes and increase the cloud point of alcohol ethoxylates. In sulfate/amine-oxide mixtures, models of experimental data suggest that both high-acid and high-lactone sophorolipids can replace 40–50% of the primary surfactants without significant changes to the surface tension or foaming performance. These findings will enable the next-generation of high performing sustainable cleaning formulations to be realized.</p>","PeriodicalId":17083,"journal":{"name":"Journal of Surfactants and Detergents","volume":"27 5","pages":"769-780"},"PeriodicalIF":1.6,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141342887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The upcycling of waste frying oil and the effect on sophorolipid productivity 废弃煎炸油的循环利用及其对羊脂生产率的影响
IF 1.6 4区 工程技术
Journal of Surfactants and Detergents Pub Date : 2024-06-11 DOI: 10.1002/jsde.12779
Ryu Ishizaki, Michiaki Araki, Glen Lelyn Quan, Yoshihiko Hirata
{"title":"The upcycling of waste frying oil and the effect on sophorolipid productivity","authors":"Ryu Ishizaki,&nbsp;Michiaki Araki,&nbsp;Glen Lelyn Quan,&nbsp;Yoshihiko Hirata","doi":"10.1002/jsde.12779","DOIUrl":"10.1002/jsde.12779","url":null,"abstract":"<p>Waste frying oil (WFO) is a degraded form of oil that is produced from repeated exposure to high temperatures during cooking. Many research studies have focused on the use of recycled WFO. These studies are highly promoted because of the need to find new ways of reducing the negative impact of WFO on the environment. One of these studies focused on the production of sophorolipid (SL), a naturally derived eco-friendly glycolipid biosurfactant. Unfortunately, the environmental and societal advantages brought about by the wide-spread use of SL are offset by its high production cost. WFO is a high-volume, inexpensive material that can be used as a substrate for SL production. As such, by utilizing WFO as a feedstock material cost reduction can be realized to improve large-scale application potential. One drawback to the use of WFO is that its physical characteristics are different from fresh oil and its effect on SL productivity (g/day) has not been investigated. This research focused on the effect of acid value (AV), peroxide value (PV), and carbonyl value (CV) of WFO on SL productivity. It was confirmed that SL titers (111.1 vs. 106.7 g/L) did not differ significantly after using either fresh oil (CV &lt;0.01) or WFO, respectively. In addition, this research also confirmed that higher WFO degradation required longer culture periods (from 6 days to 9 days) to reach comparable SL concentrations as that produced with fresh oil.</p>","PeriodicalId":17083,"journal":{"name":"Journal of Surfactants and Detergents","volume":"27 5","pages":"703-710"},"PeriodicalIF":1.6,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141355401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of hydrocarbon marine pollution with cloud point extraction 利用浊点萃取技术处理碳氢化合物海洋污染
IF 1.6 4区 工程技术
Journal of Surfactants and Detergents Pub Date : 2024-06-06 DOI: 10.1002/jsde.12776
H. Ghouas, B. Haddou, J. P. Canselier, M. Kameche
{"title":"Treatment of hydrocarbon marine pollution with cloud point extraction","authors":"H. Ghouas,&nbsp;B. Haddou,&nbsp;J. P. Canselier,&nbsp;M. Kameche","doi":"10.1002/jsde.12776","DOIUrl":"10.1002/jsde.12776","url":null,"abstract":"<p>The release of hydrocarbons (HC) into the marine environment has serious consequences, both economically and ecologically. This work presents an efficient process to remove HC pollution from seawater: cloud point extraction (CPE), considered to be a reliable, inexpensive, and environmentally friendly method, using the readily biodegradable nonionic surfactants Lutensol ON30 and Tergitol 15-S-7. A real salt water sample with a high chemical oxygen demand (COD = 1700 mg O<sub>2</sub>/L) was thus treated. First, the phase diagrams of the binary systems (water–surfactant), and the pseudo-binary systems (water–surfactant–HC), were determined. Second, after a 24 h settling time, considered as optimal, the extraction results, that is, residual soluble COD, residual percentage of surfactant in the dilute phase and volume fraction of coacervate at equilibrium, were expressed in terms of temperature and initial surfactant concentration. For each parameter, the results obtained were modeled using the response surface methodology and represented on three-dimensional diagrams. They show that the COD can be reduced to 10 and 15 mg O<sub>2</sub>/L, using Lutensol ON30 and Tergitol 15-S-7, respectively, under seawater temperature conditions. Finally, it was shown that the surfactant can be recycled. The present work demonstrates that CPE can reduce the HC content of seawater on a laboratory scale.</p>","PeriodicalId":17083,"journal":{"name":"Journal of Surfactants and Detergents","volume":"27 6","pages":"949-961"},"PeriodicalIF":1.6,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jsde.12776","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141378581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of non-palm triglyceride feedstocks on surfactant properties and consumer product applications 非棕榈油甘油三酯原料对表面活性剂特性和消费品应用的影响
IF 1.6 4区 工程技术
Journal of Surfactants and Detergents Pub Date : 2024-06-06 DOI: 10.1002/jsde.12749
Nancy Falk
{"title":"Impact of non-palm triglyceride feedstocks on surfactant properties and consumer product applications","authors":"Nancy Falk","doi":"10.1002/jsde.12749","DOIUrl":"10.1002/jsde.12749","url":null,"abstract":"<p>Increased demand and sustainability concerns for palm derivatives, which include the major plant-based feedstocks for surfactants in household, personal care, and industrial &amp; institutional (I&amp;I) applications, is anticipated to cause supply concerns over the next decade. This article reviews the impact of the fatty acid alkyl chain length and unsaturation and resulting physical properties from non-palm feedstocks on formulation, processing, and functionality. Potential adjustments and their limitations are also discussed.</p>","PeriodicalId":17083,"journal":{"name":"Journal of Surfactants and Detergents","volume":"27 6","pages":"837-845"},"PeriodicalIF":1.6,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jsde.12749","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141375900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and trend of dairy cleaning agents 乳制品清洁剂的发展和趋势
IF 1.6 4区 工程技术
Journal of Surfactants and Detergents Pub Date : 2024-06-05 DOI: 10.1002/jsde.12768
Hong Su, Jing Chai, Xiang Li, Yangzhi Kong, Yanling Zhang, Jing Kang, Alideertu Dong
{"title":"Development and trend of dairy cleaning agents","authors":"Hong Su,&nbsp;Jing Chai,&nbsp;Xiang Li,&nbsp;Yangzhi Kong,&nbsp;Yanling Zhang,&nbsp;Jing Kang,&nbsp;Alideertu Dong","doi":"10.1002/jsde.12768","DOIUrl":"10.1002/jsde.12768","url":null,"abstract":"<p>The quality and safety of dairy products are highly valued by consumers and dairy manufacturers, which is mainly ensured by thorough cleaning of dairy production equipment. Milk fouling can cause pipes to clog and reduce transmission. Incomplete cleaning can cause microbial breeding, which will affect the quality and safety of dairy products. To achieve efficient and rapid cleaning of dairy processing equipment, cleaning agents have always been a necessary choice for dairy and food enterprises. This paper describes the production mechanism of milk fouling, the cleaning mechanism by cleaning agents, and the cleaning process. Development of cleaning agents are introduced in detail, include compound alkaline/acid/neutral cleaning agents, enzyme cleaning agents and cleaning additives. The factors affecting cleaning efficiency are also viewed, which include type and dosage of cleaning agents, cleaning process (cleaning time, cleaning liquid temperature, cleaning fluid flow rate), and other influencing factors (cleaning fluid pressure, Reynolds number and shear stress, surface types). Four aspects are reviewed in this manuscript, include cleaning objects (milk fouling), cleaning substances (cleaning agents), how to clean (cleaning mechanism) and how to clean efficiently (cleaning influencing factors), which provides a valuable reference for the improvement of the dairy cleaning process.</p>","PeriodicalId":17083,"journal":{"name":"Journal of Surfactants and Detergents","volume":"27 4","pages":"465-481"},"PeriodicalIF":1.6,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141385623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Studies on the properties and molecular dynamics simulations of nonionic surfactants based on succinic acid derivatives 基于琥珀酸衍生物的非离子表面活性剂的特性研究与分子动力学模拟
IF 1.6 4区 工程技术
Journal of Surfactants and Detergents Pub Date : 2024-06-04 DOI: 10.1002/jsde.12778
Feng Luo, Wannian Zhang, Fang Yu, Jinlong Wang, Yu-Peng He
{"title":"Studies on the properties and molecular dynamics simulations of nonionic surfactants based on succinic acid derivatives","authors":"Feng Luo,&nbsp;Wannian Zhang,&nbsp;Fang Yu,&nbsp;Jinlong Wang,&nbsp;Yu-Peng He","doi":"10.1002/jsde.12778","DOIUrl":"10.1002/jsde.12778","url":null,"abstract":"<p>Nonionic surfactants have proven useful in various applications such as wastewater treatment, enhanced oil recovery, dyeing, and cosmetics. Novel nonionic surfactants such as <b>PEMP</b>, <b>BEMP</b>, <b>HEMP</b> and <b>BEEP</b> were synthesized based on succinic acid derivatives and using L-isoleucine as the linking group and four polyether alcohols as the hydrophilic group. First, the structures of the four nonionic surfactants were studied using Fourier transform infrared (FTIR) spectroscopy and nuclear magnetic resonance (NMR) spectra. Then the critical micelle concentration (CMC) and surface tension at CMC (γCMC) of the four nonionic surfactants in aqueous solution were tested. γ-lg c curves determined the relationships of their surface properties as <b>BEEP</b> &gt; <b>PEMP</b> &gt; <b>BEMP</b> &gt; <b>HEMP</b>. In order to expand the range of applications for nonionic surfactants, we evaluated the salt-resistant properties of four such surfactants. Our findings demonstrated that this class of surfactants indeed has superior salt-resistant properties. Molecular dynamics (MD) simulations were used to study how surfactant molecules aggregate in the interfacial film. The study investigated the trend of solvent accessible surface area (SASA) over time. Results showed that the surfactant molecules interacted well with solvent molecules in the equilibrium state. This study investigates the performance differences among four types of surfactants using the electrostatic potential (ESP) distribution of their molecules. The study employed both experimental and computational simulations to provide a more comprehensive understanding of surfactant properties. The results offer insights into the theoretical research and application extension of this class of surfactants.</p>","PeriodicalId":17083,"journal":{"name":"Journal of Surfactants and Detergents","volume":"28 1","pages":"77-84"},"PeriodicalIF":1.6,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141265873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interfacial properties and foam performance of alpha olefin sulfonate and CO2 switchable aminopropyl methyl siloxane surfactant mixtures α-烯烃磺酸盐和二氧化碳可转换氨丙基甲基硅氧烷表面活性剂混合物的界面特性和泡沫性能
IF 1.6 4区 工程技术
Journal of Surfactants and Detergents Pub Date : 2024-05-28 DOI: 10.1002/jsde.12767
Yujie Zhao, Jun Qiu, Xuedong Zhu, Xiujuan He, Yingcheng Li
{"title":"Interfacial properties and foam performance of alpha olefin sulfonate and CO2 switchable aminopropyl methyl siloxane surfactant mixtures","authors":"Yujie Zhao,&nbsp;Jun Qiu,&nbsp;Xuedong Zhu,&nbsp;Xiujuan He,&nbsp;Yingcheng Li","doi":"10.1002/jsde.12767","DOIUrl":"10.1002/jsde.12767","url":null,"abstract":"<p>CO<sub>2</sub>-in-water (C/W) foams have attracted much attention given their eco-friendliness in recent years. However, limited surfactants were able to effectively adsorb at the supercritical CO<sub>2</sub>–water (C–W) interface considering the weak solvent strength of CO<sub>2</sub>, especially at high temperatures. Herein, attempts have been made to design suitable CO<sub>2</sub> foaming agents by evaluating the influence of proportions of anionic and cationic surfactants and the affinity between aminopropyl methyl siloxane (APSi) and CO<sub>2</sub>. Through systematical foamability and foam stability experiments, together with the measurements of C–W equilibrium and dynamic interfacial tensions, the adsorption and stabilization mechanisms of sodium alpha olefin sulfonate (AOS)-APSi aqueous dispersions on the CO<sub>2</sub> foam films are revealed. Excellent foam properties were observed at AOS/APSi mass ratio of 9:1, in which initial foam height (<i>h</i><sub>0</sub>) and half-life period (<i>t</i><sub>1/2</sub>) first increased and then decreased with increasing pressure, whereas the interfacial tension decreased with increasing pressure. The results indicate that the interaction of anionic and cationic head-groups contributes to accelerating the surfactant adsorption rate from bulk to the C–W interface, enhancing foamability and stabilizing foam. Besides, the AOS/APSi mass ratio of 8:2 shows a good affinity for CO<sub>2</sub> at 15 MPa, of which <i>h</i><sub>0</sub> is 26% higher and <i>t</i><sub>1/2</sub> is 60% slower than AOS alone. Furthermore, the initial mean bubble area of both 9:1 and 8:2 AOS/APSi mixtures was around half that of AOS alone. This work broadens the design of novel surfactant methodologies including CO<sub>2</sub> foam, providing a theoretical guidance for the application of CO<sub>2</sub> on enhanced-oil-recovery technologies.</p>","PeriodicalId":17083,"journal":{"name":"Journal of Surfactants and Detergents","volume":"27 4","pages":"589-603"},"PeriodicalIF":1.6,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141189152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surfactants produced from carbohydrate derivatives: Part 2. A review on the value chain, synthesis, and the potential role of artificial intelligence within the biorefinery concept 用碳水化合物衍生物生产的表面活性剂:第 2 部分。价值链、合成和人工智能在生物精炼概念中的潜在作用综述
IF 1.6 4区 工程技术
Journal of Surfactants and Detergents Pub Date : 2024-05-21 DOI: 10.1002/jsde.12766
Ronald Marquez, Maria S. Ortiz, Nelson Barrios, Ramon E. Vera, Álvaro Javier Patiño-Agudelo, Keren A. Vivas, Mariangeles Salas, Franklin Zambrano, Eric Theiner
{"title":"Surfactants produced from carbohydrate derivatives: Part 2. A review on the value chain, synthesis, and the potential role of artificial intelligence within the biorefinery concept","authors":"Ronald Marquez,&nbsp;Maria S. Ortiz,&nbsp;Nelson Barrios,&nbsp;Ramon E. Vera,&nbsp;Álvaro Javier Patiño-Agudelo,&nbsp;Keren A. Vivas,&nbsp;Mariangeles Salas,&nbsp;Franklin Zambrano,&nbsp;Eric Theiner","doi":"10.1002/jsde.12766","DOIUrl":"10.1002/jsde.12766","url":null,"abstract":"<p>This comprehensive and critical review explores the synthesis and applications of carbohydrate-based surfactants within the biorefinery concept, focusing on biobased sugar-head molecules suitable for use across several manufacturing sectors, including cosmetics, pharmaceuticals, household products, detergents, and foods. The main focus relies on sustainable alternatives to conventional surfactants, which could reduce the final manufacturing carbon footprint of several industrial feedstocks and products. A thorough analysis of raw materials, highlighting the significance of feedstock sources, and the current biobased surfactants and rhamnolipid biosurfactants production trends, is presented. Key organic reactions for the production of sorbitan esters, sucrose esters, alkyl polyglycosides, and fatty acid glucamines, such as glycosidation, acylation, and etherification, as well as the production of rhamnolipids through fermentation are described. Given the scarce literature on the characterization of these surfactant types within the hydrophilic–lipophilic deviation (HLD) framework, the surfactant contribution parameter (SCP) in the HLD equation for sugar-head surfactants is critically assessed. The economic landscape is also discussed, noting the significant growth in the biobased surfactants and biosurfactant market, driven by environmental awareness and regulatory changes, with projections indicating a substantial market increase in the forthcoming years. Finally, the promising potential of generative artificial intelligence (AI) in developing customized surfactant molecules, with optimized properties for targeted applications, is emphasized as a promising avenue for future research.</p>","PeriodicalId":17083,"journal":{"name":"Journal of Surfactants and Detergents","volume":"28 1","pages":"25-76"},"PeriodicalIF":1.6,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jsde.12766","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141116825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preparation, characterization, and in vitro evaluation of microemulsion based cream formulations for the topical treatment of acne vulgaris 用于局部治疗寻常型痤疮的微乳剂配方的制备、表征和体外评估
IF 1.6 4区 工程技术
Journal of Surfactants and Detergents Pub Date : 2024-05-21 DOI: 10.1002/jsde.12769
Emre Şefik Çağlar, Rengin Reis, Ayşe Esra Karadağ, Fatih Demirci, Hande Sipahi, Ahmet Aydın, Neslihan Üstündağ Okur
{"title":"Preparation, characterization, and in vitro evaluation of microemulsion based cream formulations for the topical treatment of acne vulgaris","authors":"Emre Şefik Çağlar,&nbsp;Rengin Reis,&nbsp;Ayşe Esra Karadağ,&nbsp;Fatih Demirci,&nbsp;Hande Sipahi,&nbsp;Ahmet Aydın,&nbsp;Neslihan Üstündağ Okur","doi":"10.1002/jsde.12769","DOIUrl":"10.1002/jsde.12769","url":null,"abstract":"<p>By lowering the significant adverse effects of traditional medications, this study intends to create cream formulations based on microemulsions that contain extract from <i>Allium sativum</i> L. for the treatment of acne vulgaris. Characterization experiments were carried out on the developed cream formulations based on microemulsions. Textural profile analysis and spreadability tests were conducted. Furthermore, cell culture studies and toxicity analysis were performed. As a result, the pH and viscosity values of the developed formulations were found between 6.43 ± 0.00 and 6.66 ± 0.01, and between 13.90 ± 0.080 and 137.20 ± 8.02 P, respectively. The highest-performing empty and loaded cream formulations in terms of spreadability and textural profile analysis were those with the highest beeswax content. The highest-performing empty and loaded cream formulations in terms of spreadability and textural profile analysis were those with the highest beeswax content. According to the visual physical evaluation of the formulations, it was observed that the developed formulations were neat, smooth, and homogeneous. The optimum formulation developed was non-cytotoxic, which maintained cell viability by over 90%. Additionally, the skin irritation experiment was also non-irritant with a relative cell viability of 92.6%. In conclusion, the developed <i>A. sativum</i> extract-loaded microemulsion-based cream formulations appear to be promising formulations for the acne vulgaris treatment, without malodors.</p>","PeriodicalId":17083,"journal":{"name":"Journal of Surfactants and Detergents","volume":"28 1","pages":"13-24"},"PeriodicalIF":1.6,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141153796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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