Journal of Sulfur Chemistry最新文献

{"title":"Design and synthesis of abietic acid derivatives containing sulfonamide structure, biological activity and mechanism of action studies","authors":"Song Bai ,&nbsp;Lijun Chen ,&nbsp;Miao Li ,&nbsp;Suran Wan ,&nbsp;Fang Wang ,&nbsp;Shouyin Tang ,&nbsp;Xian Wei ,&nbsp;Rong Wu","doi":"10.1080/17415993.2025.2507054","DOIUrl":"10.1080/17415993.2025.2507054","url":null,"abstract":"<div><div>Through active splicing techniques and chemical synthesis methods, we have successfully synthesized a series of novel abietic acid derivatives that combine abietic acid backbone with a sulfonamide group. <em>In vitro</em> tests, these derivatives exhibited remarkable antibacterial activities, especially compound <strong>C3</strong>. Using three-dimensional quantitative structure–activity relationship (3D-QSAR) analysis, we found that the introduction of electron-absorbing groups at the R¹ position, as well as the introduction of larger groups at the R² position, may enhance the antibacterial activity of the target compounds. In addition, studies on the antibacterial mechanism of action of compound <strong>C3</strong> showed that it could increase the permeability of bacterial membranes, disrupt the cell membrane of <em>Xanthomonas oryzae</em> pv. <em>oryzicola</em> (<em>Xoc</em>), and effectively inhibit bacterial growth. These findings not only elucidate the antibacterial mechanism of <strong>C3</strong>, but also provide an important scientific basis for the design and development of new antibacterial agents.</div></div>","PeriodicalId":17081,"journal":{"name":"Journal of Sulfur Chemistry","volume":"46 5","pages":"Pages 818-834"},"PeriodicalIF":1.6,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent advances in synthetic approaches for biologically active organic dithiocarbamates","authors":"Babli Roy","doi":"10.1080/17415993.2025.2497317","DOIUrl":"10.1080/17415993.2025.2497317","url":null,"abstract":"<div><div>The chemically and medicinally versatile dithiocarbamates play a significant role in advancing various fields, including agriculture, chemical synthesis, and environmental remediation. However, dithiocarbamates have primarily been utilised as pesticides and fungicides for crop protection since the 1930s. Recently, the revival of dithiocarbamates from agrochemicals to repurposed drugs for treating life-threatening diseases like cancer and microbial infections has stimulated medicinal chemists to reinvestigate their unmet potential. Furthermore, dithiocarbamates containing diversified organic functionalities have shown promising antifungal activity against fungal-resistant phytopathogens, offering a solution to addressing the global threat of fungal resistance. Consequently, the synthesis of multifaceted S and N-functionalized organic dithiocarbamates using diverse organic substrates has resurfaced in synthetic and medicinal chemistry research. There is also a growing trend to develop more convenient synthetic approaches for synthesising organic dithiocarbamates featuring various green chemistry aspects, including alternative or renewable energy resources, green solvents, solvent-free reaction conditions, and cost-effectiveness. These greener approaches are also associated with high efficiency, better selectivity, broad substrate scope, outstanding yields, operational simplicity, and viability. This review provides an in-depth overview of the recent developments in the diverse synthetic routes for preparing novel organic dithiocarbamates, including multi-component approaches involving the reaction of amines, carbon disulfide, and a wide range of organic substrates. The emerging methodologies for directly synthesising S-alkyl and S-aryl dithiocarbamates using commercially available and non-hazardous tetraalkylthiuram disulfides or monosulfides as organic precursors are also comprehensively discussed in this article. This review also highlights recently developed unconventional greener protocols using alternative reactants instead of carbon disulfide or thiuram disulfides.</div></div>","PeriodicalId":17081,"journal":{"name":"Journal of Sulfur Chemistry","volume":"46 5","pages":"Pages 922-974"},"PeriodicalIF":1.6,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel tetrathiafulvalene-based organogelator with multi-stimuli responsiveness and dye adsorption","authors":"Zhilong Li ,&nbsp;Yan Xia ,&nbsp;Dongfeng Li ,&nbsp;Ruibin Hou","doi":"10.1080/17415993.2025.2510420","DOIUrl":"10.1080/17415993.2025.2510420","url":null,"abstract":"<div><div>To create multi-stimulus responsive organogels, a novel low-molecular-weight organic gelator (LMMG) 1 was synthesized by linking two photoresponsive azobenzene groups with two hydrophobic chains containing amide functionalities to a central electroactive tetrathiafulvalene (TTF) unit. The gelation properties of compound 1 were comprehensively evaluated, revealing its ability to immobilize 1,2-dichloroethane and n-butanol, while other solvents tested did not form gels. A series of analyses, including SEM, FTIR, ¹H NMR, and UV/Vis absorption spectroscopy, were conducted to investigate the characteristics of the resulting organogels. The findings indicated that the gelator self-assembled into a three-dimensional supramolecular network, driven by intermolecular hydrogen bonding. As anticipated, the organogels displayed multiple stimuli-responsive sol–gel transitions in response to changes in chemical redox conditions, heating, and the presence of anions due to the dynamic and reversible nature of the non-covalent interactions. Notably, the gelators interacted with various electron acceptor molecules, resulting in the formation of charge transfer (CT) complexes and binary organogels, accompanied by noticeable color changes. Additionally, the gels proved to be effective absorbents, suggesting potential applications for the removal of Rhodamine B cationic dyes from water.</div></div>","PeriodicalId":17081,"journal":{"name":"Journal of Sulfur Chemistry","volume":"46 5","pages":"Pages 887-903"},"PeriodicalIF":1.6,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green microwave-assisted synthesis, characterization, and PXRD studies of nitrogen- and sulfur-containing Schiff base platinum (II) complexes: evaluation of antituberculosis, DNA cleavage, and antimicrobial activities","authors":"Akshita Jain ,&nbsp;Shivansh Bhatnagar ,&nbsp;Anita Kumari ,&nbsp;Saurabh Dave ,&nbsp;Nighat Fahmi","doi":"10.1080/17415993.2025.2535433","DOIUrl":"10.1080/17415993.2025.2535433","url":null,"abstract":"<div><div>In the pursuit of pharmacologically important compounds, platinum(II) complexes were synthesized using both green microwave-assisted and thermal methods with the bidentate NS Schiff base ligand benzyl-2-(1-(pyridine-2-yl)ethylidene)hydrazine-1-carbodithioate (HL). This ligand was synthesized through the reaction between benzyl hydrazinecarbodithioate and 1-(pyridine-2-yl)ethan-1-one. The results from both methods were summarized and compared. Microwave-assisted reactions were completed in a shorter time and yielded higher amounts of product compared to thermal methods. The structural characterization of both the ligand and metal complexes was performed using various physicochemical methods. A square planar geometry was inferred for the platinum(II) complexes based on spectral and analytical data. Both the ligand (HL) and the platinum complex, [Pt(L)₂] were evaluated for antituberculosis, DNA cleavage, and antimicrobial activities. Additionally, the [Pt(HL)₂]Cl₂ complex was also investigated for antimicrobial activity. The platinum complex, [Pt(L)₂] was found to effectively inhibit the growth of <em>Mycobacterium tuberculosis</em>. DNA cleavage studies suggested that both the ligand and the metal complex, [Pt(L)₂] were able to completely cleave <em>Staphylococcus aureus</em> DNA. Antimicrobial testing showed that both the ligand and the metal complexes exhibited activity against two bacteria (<em>Escherichia coli</em> and <em>Bacillus subtilis</em>) and two fungi (<em>Aspergillus niger</em> and <em>Penicillium chrysogenum</em>), demonstrating antibacterial and antifungal effects.</div></div>","PeriodicalId":17081,"journal":{"name":"Journal of Sulfur Chemistry","volume":"46 5","pages":"Pages 904-921"},"PeriodicalIF":1.6,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"N-methyl-P,P-diphenyl-N-(2-pyridinyl)phosphinothioic amide chelating ligand: synthesis, characterization, and X-ray structures of novel Hg(II) metal complexes","authors":"Harbi Tomah Al-Masri ,&nbsp;Akram Ali Almejled ,&nbsp;Ziad Moussa","doi":"10.1080/17415993.2025.2508810","DOIUrl":"10.1080/17415993.2025.2508810","url":null,"abstract":"<div><div><em>N</em>-methyl-<em>P</em>,<em>P</em>-diphenyl-<em>N</em>-(2-pyridinyl)phosphinous amide was oxidized with elemental sulfur in refluxing toluene to produce the corresponding sulfide C₆H₃N-2-N(CH₃)(P(S)Ph₂) (<strong>1</strong>) ligand. The reaction of <strong>1</strong> with an equimolar quantity of HgX₂ (X = Cl, I) produced <em>cis</em>-[HgX₂{<strong>1</strong>-κ²<em>S,N^py</em> }] (X = Cl(<strong>2</strong>), I(<strong>3</strong>)) complexes. In addition, the side product Ph₂P(S₂).C₆H₄N(CH₃)(H) (<strong>4</strong>) was identified while ligand <strong>1</strong> was being prepared. <strong>1</strong>–<strong>4</strong> were characterized using multinuclear NMR (¹H, ¹³C, and ³¹P) and IR spectroscopy. The molecular structures of <strong>1</strong>–<strong>4</strong> were determined using a single X-ray crystallography. <strong>2</strong> and <strong>3</strong> are structurally characterized novel κ²<em>S,N^py</em>-bidentate ligands with Hg(II) metal complexes.</div></div>","PeriodicalId":17081,"journal":{"name":"Journal of Sulfur Chemistry","volume":"46 5","pages":"Pages 806-817"},"PeriodicalIF":1.6,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nickel(II) unsymmetrical Schiff base complex immobilized on boehmite nanoparticles: a novel and efficient heterogeneous catalyst for selective oxidation of sulfides and thiols","authors":"Mehdi Hatefi Ardakani ,&nbsp;Atena Naeimi ,&nbsp;Motahareh Mirahmadi","doi":"10.1080/17415993.2025.2513375","DOIUrl":"10.1080/17415993.2025.2513375","url":null,"abstract":"<div><div>In this work, first, boehmite nanoparticles were prepared by an economical and simple method using accessible materials, and functionalized with 3-chloropropyltrimethoxysilane (3-CPTMS). Then, a nickel(II) unsymmetrical salen Schiff base complex, Ni(salenac-OH), where salenac-OH = [9-(2’,4'-dihydroxyphenyl)−5,8-diaza-4-methylnona-2,4,8-trienato](−2), was synthesized and immobilized on the prepared chloro-functionalized boehmite nanoparticles. The obtained Boehmite@Ni(salenac-OH) nanoparticles were characterized using various techniques. The produced Boehmite@Ni(salenac-OH) nanoparticles were employed as an effective heterogeneous nanocatalyst for the selective oxidation of sulfides to sulfoxides using 30% H₂O₂ as a green oxidant under solvent-free conditions as well as the oxidative coupling of thiols to disulfides with 30% H₂O₂ in ethanol at room temperature (25 °C). In these protocols, the desired sulfoxides and disulfides were achieved with good to excellent yields without over-oxidation to unwanted by-products. The use of this heterogeneous nanocatalyst in the mentioned organic reaction achieved good results, including high efficiency, excellent stability, easy recovery, and reusability of the catalyst for five continuous cycles. In addition, XRD and FT-IR techniques indicated that the structure of the catalyst remained intact after the recovery process.</div></div>","PeriodicalId":17081,"journal":{"name":"Journal of Sulfur Chemistry","volume":"46 5","pages":"Pages 835-852"},"PeriodicalIF":1.6,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sulfoxide bond dissociation enthalpies predicted by DFT paired with Pople, Dunning, and Karlsruhe basis sets","authors":"Sydney S. Lahm ,&nbsp;Ryan D. McCulla","doi":"10.1080/17415993.2025.2516552","DOIUrl":"10.1080/17415993.2025.2516552","url":null,"abstract":"<div><div>Computational analysis was conducted to determine the bond dissociation enthalpies (BDEs) of S–O bonds in eight molecules, which were subsequently compared to their experimentally derived BDEs. Computational BDEs were determined utilizing various combinations of density functional theory (DFT) functionals with an assortment of basis sets. Specifically, DFT methods including M06-2X, mPW1LYP, ωB97X-D3, PBE0, and B3P86 were paired with basis sets def2-TZVP/J, def2-TZVP, aug-<em>cc</em>-pV(T + d)Z, 6-311 + G(2df,2p), and def2-QZVP. The comparison between computational and experimental BDEs was evaluated through graphical representation, yielding slope, coefficient of determination (R²), and root mean square error (RMSE) metrics. Additionally, comparative analyses were expanded to include complete basis set methods (CBS-QB3 and CBS-4M), which exhibited comparatively lower accuracy in predicting experimentally determined S–O BDEs than the DFT methods. Among all methods tested, the B3P86/aug-<em>cc</em>-pV(T + d)Z and B3P86/def2-QZVP methods are recommended for computational prediction of BDEs for sulfoxides.</div></div>","PeriodicalId":17081,"journal":{"name":"Journal of Sulfur Chemistry","volume":"46 5","pages":"Pages 853-864"},"PeriodicalIF":1.6,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solvent-free synthesis of novel 1,3-thiazolidin-4-one-5-arylidene derivatives via cyclocondensation","authors":"Tchambaga Etienne Camara ,&nbsp;Aboudramane Koné ,&nbsp;Bamoro Coulibaly ,&nbsp;Aya Stéphanie Kra ,&nbsp;Pénayori Marie-Aimée Coulibaly ,&nbsp;Souleymane Coulibaly ,&nbsp;Ballo Daouda ,&nbsp;Coulibali Siomenan","doi":"10.1080/17415993.2025.2536592","DOIUrl":"10.1080/17415993.2025.2536592","url":null,"abstract":"<div><div>The 1,3-thiazolidin-4-one scaffold is a well-known pharmacophore in medicinal chemistry, valued for its broad spectrum of biological activities.</div></div><div><div>In this study, we report the design and efficient synthesis of a new series of 1,3-thiazolidin-4-one-5-arylidene derivatives <strong>7a-j</strong>. The synthetic strategy began with the cyclocondensation of phenylhydrazide intermediates (<strong>3a</strong> and <strong>3b</strong>) with mercaptoacetic acid under solvent-free conditions, using a few drops of acetic acid. This reaction yielded the key thiazolidinone intermediates (<strong>5a</strong> and <strong>5b</strong>). Subsequent condensation with benzaldehyde or its substituted derivatives (<strong>6a – j</strong>) in the presence of sodium ethanolate (CH₃CH₂ONa) afforded the target compounds (<strong>7a – j</strong>) in yields ranging from 50% to 86%. The structures of all synthesized compounds were confirmed through details spectroscopic analyses, including ¹H, ¹³C Nuclear Magnetic Resonance (NMR), and High-Resolution Mass Spectrometry (HRMS).</div></div>","PeriodicalId":17081,"journal":{"name":"Journal of Sulfur Chemistry","volume":"46 5","pages":"Pages 795-805"},"PeriodicalIF":1.6,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of 3-(1H-benzo[d]imidazole-2-yl)-2-arylthiazolidin-4-one using Fe3O4@SiO2Pr@E-N'-(4-hydroxy-3-methoxybenzylidene) isonicotinohydrazide@Cu an efficient and magnetically retrievable nanocatalyst","authors":"Leila Zare Fekri ,&nbsp;Mohammad Nikpassand","doi":"10.1080/17415993.2025.2528777","DOIUrl":"10.1080/17415993.2025.2528777","url":null,"abstract":"<div><div>Fe₃O₄@SiO₂Pr@E-N'-(4-hydroxy-3-methoxybenzylidene) isonicotinohydrazide@Cu were prepared and were analyzed by XRD, FT-IR, VSM, TEM, FE-SEM, and TGA-DTG analysis. These nano catalysts were applied as an efficient and magnetically reusable nanocatalyst for the preparation of various derivatives of thiazolidinones under solvent-free conditions. All of the organic compounds were analyzed by NMR and FT-IR. This avenue offers many benefits, such as productivity, fast reaction, and convenience for work and recovery. The catalyst is reusable for 8 runs by decantation using an efficient magnet without notable loss in activity. This protocol has many advantages, like working better, quickly responding, and making it easy to work. This is the first report to use Fe₃O₄@SiO₂Pr@E-N'-(4-hydroxy-3-methoxybenzylidene) isonicotinohydrazide@Cu to make 3-(1H-benzo[d]imidazole-2-yl)-2-arylthiazolidin-4-ones. The reaction speed is good, and this method works well. The reaction was done without any liquid and in an environmentally friendly and gentle way. The method explained is totally new.</div></div>","PeriodicalId":17081,"journal":{"name":"Journal of Sulfur Chemistry","volume":"46 5","pages":"Pages 865-886"},"PeriodicalIF":1.6,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design, synthesis, and antitubercular evaluation of piperazinyl-pyrazolyl-2- hydrazinyl thiazole derivatives: Experimental, DFT and molecular docking insights","authors":"Yuvraj R. Sable ,&nbsp;Vishnu A. Adole ,&nbsp;Edwin A. Pithawala ,&nbsp;Rakesh D. Amrutkar","doi":"10.1080/17415993.2025.2461582","DOIUrl":"10.1080/17415993.2025.2461582","url":null,"abstract":"<div><div>In the current research, a new series of piperazinyl-pyrazolyl-2-hydrazinyl thiazole derivatives (<strong>6a-6i</strong>) were synthesized and evaluated for their antitubercular activity against <em>Mycobacterium tuberculosis</em> H37Rv. The compounds were synthesized <em>via</em> a three-component reaction involving 3-methyl-5-(4-methylpiperazin-1-yl)−1-phenyl-1<em>H</em>-pyrazole-4-carbaldehyde, thiosemicarbazide, and substituted phenacyl bromides (<strong>5a-5i</strong>) in ethanol under reflux conditions. The structures of the compounds were confirmed using ¹H NMR, ¹³C NMR, and FT-IR spectroscopy, which supported the successful formation of the thiazole core. The piperazinyl-pyrazolyl-2-hydrazinyl thiazole derivatives exhibited varying degrees of antitubercular activity, with compound <strong>6c</strong> (MIC = 1.6 µg/mL) showing the highest potency, comparable to the standard drugs isoniazid and ethambutol. The most active compounds follow the order as <strong>6c</strong> (bromo substituent) &gt; <strong>6d</strong> (fluoro substituent) = <strong>6e</strong> (methoxy substituent) &gt; <strong>6a</strong> (chloro substituent) = <strong>6 g (</strong>nitrile substituent) with MIC ranging from (1.6–12.5 µg/mL). Other derivatives also displayed significant activity (MIC = 25–100 µg/mL) in which the compound <strong>6i</strong> showed the lowest activity (MIC = 100 µg/mL). Molecular docking studies further supported its biological activity, revealing strong interactions with key residues of the target protein. The DFT analysis demonstrated that substituents such as bromine, methoxy, and fluorine affected the HOMO–LUMO energy gaps (3.89 , 3.80, and 3.88 eV, respectively) and global softness (0.517–0.526 eV^-1). ADME studies confirmed favorable pharmacokinetics for <strong>6c</strong>, <strong>6d</strong>, and <strong>6e</strong>.</div></div>","PeriodicalId":17081,"journal":{"name":"Journal of Sulfur Chemistry","volume":"46 3","pages":"Pages 513-538"},"PeriodicalIF":2.1,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144105790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}