JOURNAL OF SCIENTIFIC RESEARCH最新文献_第10页

Synthesis and in vitro Biological Studies of Copper Complexes Derived from Some Novel Hetero-Organoselanylquinoline Ligands 新型杂有机基喹啉配体铜配合物的合成及体外生物学研究

JOURNAL OF SCIENTIFIC RESEARCH Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.56544

P. Moohambihai, K. Nagashri

{"title":"Synthesis and in vitro Biological Studies of Copper Complexes Derived from Some Novel Hetero-Organoselanylquinoline Ligands","authors":"P. Moohambihai, K. Nagashri","doi":"10.3329/jsr.v14i2.56544","DOIUrl":"https://doi.org/10.3329/jsr.v14i2.56544","url":null,"abstract":"A set of copper(II) complexes (3a-i) comprises (16E)-N-(2-phenylquinolin-4(1H)-ylidene)-3-(phenlselanyl)pyridine-2-amine (L1-L3), (16E)-2,6-dimethyl-N-(2-phenylquinolin-4(1H)-ylidene)-5-(phenlselanyl)pyrimidine-4-amine (L4-L6), 16E)-N-(2-phenylquinolin-4(1H)-ylidene)-2-(phenylselanyl)H-imidazo[1,2-α]pyridine-3-amine (L7-L9) ligands were synthesised and characterised using spectroscopic techniques. The metal-to-ligand 1:1 stoichiometry of prepared copper complexes was confirmed by mass spectra. The Cu(II) ion produces complexes with a distorted square planar, according to UV–Vis and ESR spectroscopy studies. The antioxidant activity of these complexes has been determined. The cytotoxic potential of the complexes was also investigated in vitro. The complex 3f was found to have significant cytotoxicity against MCF-7. The DNA binding characteristics of copper(II) complexes were investigated. The findings indicate that the complexes interacted with the calf thymus (CT-DNA). In addition, the complexes were tested in vitro for antimicrobial activity against three Gram-negative bacteria, three Gram-positive bacteria, and three Fungi.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86407030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On Certain Quadruple Fixed Points of Integral Type Contraction Mappings in G-Metric Spaces and its Applications g -度量空间中积分型收缩映射的若干四重不动点及其应用

JOURNAL OF SCIENTIFIC RESEARCH Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.56189

B. Rao, L. V. Kumar, C. Maheswari, S. M. Shaw

引用次数: 0

Modeling of the Peristaltic Lithogeic Bile Flow in the Calculus Duct Under the Influence of Heat Transfer with Slip Boundary Conditions 滑移边界条件下换热影响下结石管内岩石胆汁蠕动流动的模拟

JOURNAL OF SCIENTIFIC RESEARCH Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.55882

T. Rawat, S. Kumari, S. Singh

引用次数: 0

GC-MS, Phytochemical Analysis and In Silico Approaches of a Medicinal Plant Acalypha indica 药用植物白果的气相色谱-质谱、植物化学分析及计算机方法研究

JOURNAL OF SCIENTIFIC RESEARCH Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.56648

P. Rajkumar, S. Sundari, S. Selvaraj, A. Natarajan, R. Suganya, R. Jayaprakash, K. Kasthuri, S. Kumaresan

{"title":"GC-MS, Phytochemical Analysis and In Silico Approaches of a Medicinal Plant Acalypha indica","authors":"P. Rajkumar, S. Sundari, S. Selvaraj, A. Natarajan, R. Suganya, R. Jayaprakash, K. Kasthuri, S. Kumaresan","doi":"10.3329/jsr.v14i2.56648","DOIUrl":"https://doi.org/10.3329/jsr.v14i2.56648","url":null,"abstract":"The goal of this study is to look into the preliminary phytochemical and GC-MS analyses of a methanol extract of the leaves of Acalypha indica. Alkaloids, tannins, steroids, saponins, flavonoids, glycosides, and phenolic substances are found in leaf extract after phytochemical analysis. A. indica is a plant that grows in the southern Indian state of Tamil Nadu. It has medicinal characteristics and is used as a diuretic, anthelmintic, and respiratory disorders like bronchitis, asthma, and pneumonia. The present work is designed to investigate GC-MS. Thirty compounds are found in the leaf extract. The structure-based biological activities study supported the Pass online database findings from the current study support that the use of this plant compound responsible for the anticancer activity is based on structure-based drug development. Based on in-silico results, it was shown that the interactions of hydrogen bonds, binding affinity with JAK2 kinase inhibitors, tumor suppressor proteins pRB Retinoblastoma protein, and COX-2 target proteins were compared with known values. It can be considered an increase in the possibility of conniving potential anticancer drugs as an anti-inflammatory agent.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73120999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Transgenic Peanut (Arachis hypogaea L.) Plants Conferring Enhanced Protection Against Fungal Pathogens by Expressing Tc chitinase-I Gene 转基因花生(arachhis hypogaea L.)植物表达Tc几丁质酶- 1基因增强对真菌病原体的保护作用

JOURNAL OF SCIENTIFIC RESEARCH Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.56542

R. Marka, G. S. Malothu, R. Nanna

{"title":"Transgenic Peanut (Arachis hypogaea L.) Plants Conferring Enhanced Protection Against Fungal Pathogens by Expressing Tc chitinase-I Gene","authors":"R. Marka, G. S. Malothu, R. Nanna","doi":"10.3329/jsr.v14i2.56542","DOIUrl":"https://doi.org/10.3329/jsr.v14i2.56542","url":null,"abstract":"In this study, an efficient Agrobacterium-mediated genetic transformation method followed by Tc chitiI gene for enhanced expression in peanut (Arachis hypogaea L.) cv ICG 7827 is reported. A. tumefaciens strain LBA 4404 harboring the plant transformation plasmid pBinAR contains the Tc chitI gene and nptII gene as a selectable marker. The precultured leaflet (LL) explants were infected with A. tumefaciens containing Tc chitiI gene and cocultivated on SIM (MMS+10 mg/L BAP+1 mg/L NAA+2 mg/L AgNO3) for four days. After co-cultivation, these explants were transferred to selection medium (SIM+75 mg/L Kan+250 mg/L Cefotaxime). In T0 generation, 70 % of transformation efficiency was recorded. T1 generation derived from the primary transgenic (T0) events revealed a Mendelian inheritance pattern (3:1) for the Tc chit I transgene. T1 transgenic peanut plants were tested for resistance against C. arachidicola, C. personatum, and P. arachidis by infection with the microspores using detached leaf assay. The Tc chitI gene expressed in T1 transgenic plants have shown longer incubation, longer latent period, and lower infection frequencies than non-transformed (WT) plants. A significant negative correlation was recorded between chitinase activity and the frequency of infection to the C. arachidicola, C. personatum and P. arachidis pathogens.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89315576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Total Phenolic Contents and Anti-lipooxygenase Activity of the Methanolic Extracts from Durio zibethinus Murr 紫豆醇提物总酚含量及抗脂氧化酶活性研究

JOURNAL OF SCIENTIFIC RESEARCH Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.56287

S. Adeniyi, G. Olatunji, O. Oguntoye

{"title":"Total Phenolic Contents and Anti-lipooxygenase Activity of the Methanolic Extracts from Durio zibethinus Murr","authors":"S. Adeniyi, G. Olatunji, O. Oguntoye","doi":"10.3329/jsr.v14i2.56287","DOIUrl":"https://doi.org/10.3329/jsr.v14i2.56287","url":null,"abstract":"Durio zibethinus parts (leaves, stem bark, and root) used to treat malaria fever, vermifuge, diabetes, jaundice, inflammation, and oxidative stress management prompted the investigation of their total phenolic contents and anti-lipooxygenase activities. The total phenolic concentration of D. zibethinus parts was determined spectrophotometrically after collection and extraction. The anti-inflammatory activity was estimated using a lipooxygenase assay. Total phenolic content measured in gallic acid equivalent (GAE) gave the highest levels of 6.88 ± 1.54, 23.32 ± 1.73, and 29.00 ± 3.43 mg GAE/g sample weight leaves stem bark, and root extracts, respectively. The plant extracts showed lower anti- lipooxygenase activity in leaves (IC50 µg/mL- 1.464) and stem bark (IC50 µg/mL- 1.203), but had significant activity in root (IC50 µg/mL- 1.400) compared to standard indomethacin (IC50 µg/mL- 1.660). The plant extract's declining order of anti- lipooxygenase activity follows the same trend with the phenolic contents, indicating that the extract's magnitude of anti- lipooxygenase activity is comparable with the quantity of phenolic compounds present in the extracts. Hence, the D. zibethinus extracts are a potential candidate for a plant-derived anti-inflammatory agent.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87134273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Video Summarization Using Deep Learning for Cricket Highlights Generation 使用深度学习生成板球集锦的视频摘要

JOURNAL OF SCIENTIFIC RESEARCH Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.56856

D. Gaikwad, S. Sarap, D. Dhande

{"title":"Video Summarization Using Deep Learning for Cricket Highlights Generation","authors":"D. Gaikwad, S. Sarap, D. Dhande","doi":"10.3329/jsr.v14i2.56856","DOIUrl":"https://doi.org/10.3329/jsr.v14i2.56856","url":null,"abstract":"Recently, video surveillance technology has grown pervasive in many aspects of our lives. Automatic video monitoring produces massive amounts of data that need human examination at some point. The primary emphasis is on reducing storage usage by compressing or eliminating superfluous frames without sacrificing real information. The current effort seeks to close the growing gap between the amounts of real data and the volume. Searching through key events in large video collections is time-consuming and tedious. In this paper, smart surveillance for various applications by using video summarization has been presented. A method for generating highlights has presented which pre-processes extracted Video Frames. Convolutional Neural Networks are then used to evaluate these highlighted frames. The proposed technique extracts and calculates characteristics utilized to generate summary movies. For training deep neural networks, cricket datasets have been used. Experimental results show that the proposed solution attains improved results than other advanced summarization methodologies. Experimental results show that the proposed video summarization method consistently generates high-quality reviews for all types of videos. The proposed video summarization method is easy to use, and it can also help extract highlights of cricket games with high accuracy.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86815967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Classification of Hot Jupiter Population through Statistical Framework 基于统计框架的热木星人口分类

JOURNAL OF SCIENTIFIC RESEARCH Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.56497

S. Mondal

引用次数: 0

Metronidazole and 2-Methylimidazole as Corrosion Inhibitors in Microbiologically Influenced Corrosion 甲硝唑和2-甲基咪唑在微生物影响腐蚀中的缓蚀剂作用

JOURNAL OF SCIENTIFIC RESEARCH Pub Date : 2022-05-01 DOI: 10.3329/jsr.v14i2.56113

J. Girase, P. Kamble, R. Dubey

引用次数: 0

Prevalence of anaemia in pregnant women among rural population of Kurhani block, Muzaffarpur district Bihar: A cross-sectional Primary Health Center based study 比哈尔邦Muzaffarpur区Kurhani街区农村人口孕妇贫血患病率:一项基于初级卫生中心的横断面研究

JOURNAL OF SCIENTIFIC RESEARCH Pub Date : 2022-01-01 DOI: 10.37398/jsr.2022.660506

K. Abhishek, Md Zahid Ansari, R. Topno, Madhukar, D. R. Purakayastha, Hemant Mahajan, Rakesh Bihari Verma, S. Chaturvedi, Dharmendra Kumar, Vidya Nand Rabi Das, S. Sinha, K. Kunal, Chandra Shekhar Lal, K. Pandey

{"title":"Prevalence of anaemia in pregnant women among rural population of Kurhani block, Muzaffarpur district Bihar: A cross-sectional Primary Health Center based study","authors":"K. Abhishek, Md Zahid Ansari, R. Topno, Madhukar, D. R. Purakayastha, Hemant Mahajan, Rakesh Bihari Verma, S. Chaturvedi, Dharmendra Kumar, Vidya Nand Rabi Das, S. Sinha, K. Kunal, Chandra Shekhar Lal, K. Pandey","doi":"10.37398/jsr.2022.660506","DOIUrl":"https://doi.org/10.37398/jsr.2022.660506","url":null,"abstract":"Anaemia is a major public problem which is a matter of great concern for developing countries. In India, about 63% of women of aged between15 to 49 years are anaemic. Anaemia has severe consequences on the growing child and pregnant women. In this study, pregnant women in the age range 18- 45 years who consulted the Kurhani PHC of Muzaffarpur district for regular antenatal check-up were recruited. The participants were grouped on the basis of age. The blood samples from the recruited subjects were collected and a complete blood profile was done. The median age of the pregnant women participants was 25 years. Among 345 participants, 95% of the participants were of the age group 18 - 30 years. A total of 156 (45%) pregnant women were found anaemic with 72 (20.03%) having mild anaemia, 76 (22.87%) with moderate anaemia and 8 (2.31%) were severely anaemic. The findings from this study reveal the status of anaemia among the pregnant women of the local population; which will be used to design further epidemiological studies, and will pave the ways to explore the various aspects of anaemia in pregnancy; thus contribute to fulfill the mandate of the setup of Model Rural Health Research Unit at Kurhani-Muzaffarpur, Bihar.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79457205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0