Journal of reconstructive microsurgery最新文献

筛选
英文 中文
The Impact of Intraoperative Methadone on Perioperative Opioid Requirements in Autologous Free Flap Breast Reconstruction. 术中美沙酮对自体游离皮瓣乳房重建术围术期阿片需求的影响。
IF 2.3 3区 医学
Journal of reconstructive microsurgery Pub Date : 2026-11-01 Epub Date: 2025-10-09 DOI: 10.1055/a-2717-5119
Sydney Somers, Alexandra Vitale, Aaron Dadzie, Mackenzie French, Devin Eddington, Jayant P Agarwal, Alvin C Kwok
{"title":"The Impact of Intraoperative Methadone on Perioperative Opioid Requirements in Autologous Free Flap Breast Reconstruction.","authors":"Sydney Somers, Alexandra Vitale, Aaron Dadzie, Mackenzie French, Devin Eddington, Jayant P Agarwal, Alvin C Kwok","doi":"10.1055/a-2717-5119","DOIUrl":"10.1055/a-2717-5119","url":null,"abstract":"<p><strong>Background: </strong>The use of intraoperative methadone has received considerable attention due to reports of reduced postoperative pain and opioid consumption without increased risk of opioid-related side effects. The purpose of this study was to compare perioperative opioid requirements in patients who received intraoperative methadone to those who did not receive intraoperative methadone following autologous breast reconstruction (ABR).</p><p><strong>Methods: </strong>A retrospective review of patients who underwent ABR from July 2023 to August 2024 was performed. Patients were stratified into an intraoperative methadone and nonintraoperative methadone cohort. Patient demographics, operative characteristics, hospital length of stay, and perioperative opioid consumption per patient were collected. The primary outcome was daily postoperative opioid requirements, recorded in morphine milligram equivalents (MME).</p><p><strong>Results: </strong>A total of 112 patients who underwent ABR breast reconstruction were identified, 54 in the intraoperative methadone cohort and 58 in the nonintraoperative methadone cohort. Mean opioid consumption was significantly less for the methadone cohort intraoperatively (23.7 ± 13.7 MME vs. 44.5 ± 18.8 MME, <i>p</i> < 0.01), on postoperative day (POD) 1 (29.04 ± 28.9 MME vs. 44.4 ± 37.9 MME, <i>p</i> = 0.04), POD-2 (22.9 ± 25.7 MME vs. 38.7 ± 38.2 MME, <i>p</i> = 0.04), and overall throughout hospitalization compared with the nonintraoperative methadone patients (87.4 ± 87.1 vs. 139.1 ± 121.2; <i>p</i> = 0.03).</p><p><strong>Conclusion: </strong>Intraoperative methadone significantly reduces inpatient opioid use after undergoing ABR on POD-1, POD2, and overall throughout hospitalization. Our findings support the need for well-designed prospective trials to further assess the effectiveness of intraoperative methadone in managing perioperative pain and reducing opioid use during ABR.</p>","PeriodicalId":16949,"journal":{"name":"Journal of reconstructive microsurgery","volume":" ","pages":"758-766"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reusing Motor Branches of the Neurotized Median Nerve for Functioning Free Muscle Transplantation to Augment Finger Flexion in Total Brachial Plexus Palsy. 利用神经化正中神经运动分支进行全臂丛神经麻痹患者游离肌肉移植以增强手指屈曲。
IF 2.3 3区 医学
Journal of reconstructive microsurgery Pub Date : 2026-11-01 Epub Date: 2025-11-25 DOI: 10.1055/a-2737-5342
Jennifer An-Jou Lin, Luis Mata Ribeiro, Tommy Nai-Jen Chang, David Chwei-Chin Chuang, Johnny Chuieng-Yi Lu
{"title":"Reusing Motor Branches of the Neurotized Median Nerve for Functioning Free Muscle Transplantation to Augment Finger Flexion in Total Brachial Plexus Palsy.","authors":"Jennifer An-Jou Lin, Luis Mata Ribeiro, Tommy Nai-Jen Chang, David Chwei-Chin Chuang, Johnny Chuieng-Yi Lu","doi":"10.1055/a-2737-5342","DOIUrl":"10.1055/a-2737-5342","url":null,"abstract":"<p><strong>Background: </strong>In total brachial plexus injury (BPI), there are inadequate donor nerves to adequately reinnervate the limb to regain full upper limb function. Free vascularized ulnar nerve grafts have been used to connect root stumps to the distal median nerve (MN) for hand neurotization. Axonal regeneration arrives by presenting with a sensate hand, but unpredictable motor reinnervation of the target muscles renders a paralyzed hand without extrinsic finger flexion. Thus, we describe the strategy of recycling the motor branches from the MN and replacing the forearm muscles with free functioning muscle transplantations (FFMTs).</p><p><strong>Methods: </strong>Between 1998 and 2017, a total of 34 patients received gracilis-FFMT for finger flexion, using previously reinnervated MN motor branches as the motor neurotizer. The muscle power of finger flexion [Medical Research Council (MRC)] and the satisfactory rate (≥M2) were recorded. The patient-reported outcomes, including the shortened version of the Disability of Arm, Shoulder and Hand (QuickDASH) and the Michigan Hand Outcomes Questionnaire (MHQ), were obtained.</p><p><strong>Results: </strong>About 67.7% of the patients achieved finger flexion of M2 or greater after FFMT. The average postoperative QuickDASH score significantly decreased from 76.3 ± 13.8 to 65 ± 15.8 (<i>p</i> = 0.042). The overall MHQ score showed significant improvement in the domains of overall hand function and work.</p><p><strong>Conclusion: </strong>FFMT neurotized by previously reinnervated MN branches can serve as a salvage or adjunctive strategy to augment finger flexion. The surgical strategy of recycling previously innervated MN to an FFMT helps with efficient planning of donor nerves in reconstruction for total BPI.</p>","PeriodicalId":16949,"journal":{"name":"Journal of reconstructive microsurgery","volume":" ","pages":"803-809"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145604611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Connection between Flap Type and Infection in Lower Extremity Fractures. 探讨下肢骨折皮瓣类型与感染的关系。
IF 2.3 3区 医学
Journal of reconstructive microsurgery Pub Date : 2026-11-01 Epub Date: 2025-11-05 DOI: 10.1055/a-2737-6450
Kylie R Swiekatowski, Stephen F Parlamas, Ellen B Wang, Bora Kahramangil, Imran Rizvi, Jeffrey G Trost, Mohin A Bhadkamkar
{"title":"Exploring the Connection between Flap Type and Infection in Lower Extremity Fractures.","authors":"Kylie R Swiekatowski, Stephen F Parlamas, Ellen B Wang, Bora Kahramangil, Imran Rizvi, Jeffrey G Trost, Mohin A Bhadkamkar","doi":"10.1055/a-2737-6450","DOIUrl":"10.1055/a-2737-6450","url":null,"abstract":"<p><strong>Background: </strong>Muscle flaps were historically considered superior to fasciocutaneous (FC) flaps for coverage of open fractures and exposed hardware. However, both flap types are now commonly used in modern lower extremity (LE) reconstruction, and it remains unclear whether postoperative infections rates differ. This study compares postoperative infection rates between muscle and FC flaps in free flap reconstruction following open LE fractures.</p><p><strong>Methods: </strong>A retrospective review was conducted on patients aged ≥18 years treated from 2011 to 2021 for open LE fractures requiring flap reconstruction after internal fixation. Demographics, injury characteristics, and perioperative factors were collected. The primary outcome was postoperative infection that could not be treated with antibiotics alone and required an unplanned return to the operating room for washout within 9 months of reconstruction. Univariate and multivariate analyses compared outcomes between muscle and FC flaps in free flap reconstruction.</p><p><strong>Results: </strong>Of 164 patients, 86 (52.4%) had muscle flaps and 78 (47.6%) had FC flaps. Muscle flaps were more commonly used in patients with higher injury severity scores and injuries involving the knee/lower leg. The overall postoperative infection rate was 23.2%, with no significant difference between muscle or FC flaps (25.6 vs. 20.5%, <i>p</i> = 0.56). On multivariate analysis, muscle and FC flap types were not predictors postoperative infection. Other outcomes, including reoperation, length of hospital stay postreconstruction, time to ambulation, and secondary amputation rates, were similar between flap types.</p><p><strong>Conclusion: </strong>In reconstruction of open LE fractures, muscle and FC flaps yield comparable infection rates and complication profiles. Therefore, flap selection should be guided by injury characteristics, patient factors, and reconstructive goals.</p>","PeriodicalId":16949,"journal":{"name":"Journal of reconstructive microsurgery","volume":" ","pages":"825-830"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145452291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Needle Geometry on Tissue Damage and Anastomotic Leakage: A Combined Analysis of Human Skin and Porcine Cardiovascular Models. 针形对组织损伤和吻合口漏的影响:人皮肤和猪心血管模型的联合分析。
IF 2.3 3区 医学
Journal of reconstructive microsurgery Pub Date : 2026-11-01 Epub Date: 2025-11-28 DOI: 10.1055/a-2737-5529
Daehee Jeong, Saif Badran, Joseph M Schanbacher, Christian T Potter, McKenzie E Maloney, Richard D Montilla, Justin Sacks, Gary Fudem, Carl F Schanbacher
{"title":"The Impact of Needle Geometry on Tissue Damage and Anastomotic Leakage: A Combined Analysis of Human Skin and Porcine Cardiovascular Models.","authors":"Daehee Jeong, Saif Badran, Joseph M Schanbacher, Christian T Potter, McKenzie E Maloney, Richard D Montilla, Justin Sacks, Gary Fudem, Carl F Schanbacher","doi":"10.1055/a-2737-5529","DOIUrl":"10.1055/a-2737-5529","url":null,"abstract":"<p><strong>Background: </strong>Surgical needles have evolved to optimize tissue approximation while minimizing tissue damage. Needle point geometry is a critical operative factor that impacts surgical dexterity. This study aims to compare the effects of taper point (TP) and reverse cutting (RC) needles on tissue damage and anastomotic bleeding risk across different tissue types and needle diameters.</p><p><strong>Methods: </strong>Two experimental models were employed. The Tissue Damage Model pierced 10 abdominal and 10 cheek skin samples using TP and RC needles. Histologic impact on skin layers was analyzed. The Anastomosis Leakage Model measured fluid leakage after 30 porcine aortas were punctured by TP and RC needles of varying diameters in an ex vivo pulsatile flow system. Both experiments ensured controlled variables and consistent methodologies.</p><p><strong>Results: </strong>In the Tissue Damage Model, RC needles caused twice as much dermal disruption in both abdominal and cheek skin as TP needles (<i>p</i> < 0.01). Abdominal skin exhibited twice the histological damage compared to facial skin, irrespective of needle geometry (<i>p</i> < 0.05).</p><p><strong>Results: </strong>In the Anastomosis Leakage Model, RC needles caused 5.6-, 4.0-, and 8.7-fold more leakage than TP needles at small, medium, and large needle diameters, respectively (<i>p</i> < 0.002). Leakage from RC needles increased with needle diameter (<i>p</i> < 0.001). TP needles did not exhibit this effect.</p><p><strong>Conclusion: </strong>RC needles caused significantly more dermal disruption compared to TP needles. Greater tissue damage was observed in abdominal skin than in facial skin. Additionally, RC needles led to progressively higher fluid leakage as needle diameter increased, while TP needles did not.</p>","PeriodicalId":16949,"journal":{"name":"Journal of reconstructive microsurgery","volume":" ","pages":"795-802"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145635111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preoperative Deep and Superficial Venous Thrombosis in Limb Salvage Candidates: A Contraindication to Microsurgical Free Flap Reconstruction? Lessons Learned from Our 13-year Institutional Experience. 残肢患者术前深浅静脉血栓形成:显微外科游离皮瓣重建的禁忌症?13年机构经验的教训
IF 2.3 3区 医学
Journal of reconstructive microsurgery Pub Date : 2026-11-01 Epub Date: 2025-11-17 DOI: 10.1055/a-2717-4448
Rachel N Rohrich, Hannah Soltani, Ryan P Lin, Sami Ferdousian, Karen R Li, Meghan E Currin, Lelia I Jones, Richard C Youn, Christopher E Attinger, Cameron M Akbari, Karen K Evans
{"title":"Preoperative Deep and Superficial Venous Thrombosis in Limb Salvage Candidates: A Contraindication to Microsurgical Free Flap Reconstruction? Lessons Learned from Our 13-year Institutional Experience.","authors":"Rachel N Rohrich, Hannah Soltani, Ryan P Lin, Sami Ferdousian, Karen R Li, Meghan E Currin, Lelia I Jones, Richard C Youn, Christopher E Attinger, Cameron M Akbari, Karen K Evans","doi":"10.1055/a-2717-4448","DOIUrl":"10.1055/a-2717-4448","url":null,"abstract":"<p><strong>Background: </strong>Although arterial inflow considerations dominate microsurgical planning, venous outflow is equally vital for flap survival. Patients requiring free tissue transfer (FTT) for lower extremity (LE) reconstruction frequently present with occult preoperative venous thrombosis (VT), yet there are little data guiding perioperative management in this setting. This study examines the prevalence and clinical characteristics of patients with preoperative venous thrombosis (VT) undergoing LE FTT, as well as postoperative outcomes, to evaluate the feasibility of successful microsurgery in this high-risk cohort.</p><p><strong>Methods: </strong>A retrospective review of patients with preoperative VT undergoing LE FTT at a single institution was conducted.</p><p><strong>Results: </strong>Among 279 patients, 43 (15.4%) were positive for VT. The overall deep VT (DVT) incidence in this population was 5.7% (<i>n</i> = 16/279) and the superficial VT (SVT) incidence was 10.0% (<i>n</i> = 28/279). Most thromboses were chronic (67.8%). There were two cases of takeback (4.7%) due to thrombosis (one arterial and one venous), of which one flap was salvaged. By a median follow-up duration of 9.7 months, a limb salvage rate of 88.4% was achieved.</p><p><strong>Conclusion: </strong>Preoperative VT is common in microsurgical candidates for limb salvage; however, it is not a contraindication to FTT if proper adjustments are made perioperatively. Considerations include (1) routine use of venous ultrasound to identify VT; (2) perioperative anticoagulation management, including IVC filter placement when indicated; (3) selection of recipient veins that are unaffected by VT; (4) prioritizing the use of two deep veins for anastomosis when feasible; and (5) incorporating implantable devices to monitor venous outflow.</p>","PeriodicalId":16949,"journal":{"name":"Journal of reconstructive microsurgery","volume":" ","pages":"750-757"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145541224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Use of Artificial Intelligence in Responding to Patient Questions About Anterolateral Thigh Flap Surgery for Diabetic Foot Ulcers. 人工智能在糖尿病足溃疡大腿前外侧皮瓣手术患者问题回答中的应用
IF 2.3 3区 医学
Journal of reconstructive microsurgery Pub Date : 2026-11-01 Epub Date: 2025-11-05 DOI: 10.1055/a-2737-5287
Luke J Llaurado, Kishan S Shah, Isabel A Snee, Rachel N Rohrich, Ryan J Bender, Nicole C Episalla, Richard C Youn, Karen K Evans
{"title":"The Use of Artificial Intelligence in Responding to Patient Questions About Anterolateral Thigh Flap Surgery for Diabetic Foot Ulcers.","authors":"Luke J Llaurado, Kishan S Shah, Isabel A Snee, Rachel N Rohrich, Ryan J Bender, Nicole C Episalla, Richard C Youn, Karen K Evans","doi":"10.1055/a-2737-5287","DOIUrl":"10.1055/a-2737-5287","url":null,"abstract":"<p><strong>Background: </strong>Diabetic foot ulcer (DFU) care represents a significant challenge in plastic and reconstructive surgery. Oftentimes, patients encounter complex articles and websites to answer questions about their surgeries, including anterolateral thigh (ALT) flaps. Artificial intelligence (AI) represents a new and simplified resource for DFU patients seeking information regarding their care. To assess ChatGPT's utility as a patient resource, we evaluated the accuracy, comprehensiveness, and safety of AI-generated responses to frequently asked questions (FAQs) related to ALT flap surgery for DFU.</p><p><strong>Methods: </strong>Ten DFU and ALT flap care FAQs were posed to ChatGPT Model 3.5 in June 2024. Four plastic surgeons evaluated responses using a 10-point Likert scale for accuracy, comprehensiveness, and danger of ChatGPT's answers. Surgeons also provided qualitative feedback. Response readability was assessed using 10 readability indexes, averaged to produce a reading grade level for each response.</p><p><strong>Results: </strong>Overall, ChatGPT answered patient questions with a mean accuracy of 9.1 ± 1.2, comprehensiveness of 8.2 ± 1.5, and danger of 2.0 ± 1.0. ChatGPT answered at a mean grade level of 19.8 ± 20.1. Qualitatively, physician reviewers complimented the organizational clarity of the responses (<i>n</i> = 4/10) and the AI's ability to provide information on possible surgical complications (<i>n</i> = 4/10). While one response was noted to present explicitly incorrect information about preoperative preparation protocols and when they should be initiated, the majority of responses (<i>n</i> = 6/10) left out key postoperative information, notably dangle protocols and compression.</p><p><strong>Conclusion: </strong>ChatGPT provides accurate and comprehensive responses to FAQs related to patients undergoing ALT flap surgery for the treatment of DFUs. The AI-generated responses were praised for organizational clarity and informative content regarding surgical complications, but lacked essential postoperative care details. Therefore, while ChatGPT is a valuable informational tool, further refinement is necessary to ensure that fully comprehensive information is provided to DFU patients.</p>","PeriodicalId":16949,"journal":{"name":"Journal of reconstructive microsurgery","volume":" ","pages":"810-817"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145452297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stacked vs. Single Free Flaps in Autologous Breast Reconstruction: A National Analysis of Clinical and Financial Outcomes. 自体乳房重建术中堆叠与单个自由皮瓣:一项全国临床结果分析。
IF 2.3 3区 医学
Journal of reconstructive microsurgery Pub Date : 2026-11-01 Epub Date: 2025-11-05 DOI: 10.1055/a-2737-5205
Nisha Gupta, Yasmine Ibrahim, Emili Elkins, Alberto R Valenzuela, Nikhil L Chervu, Saad Mallick, Peyman Benharash, Michael R DeLong
{"title":"Stacked vs. Single Free Flaps in Autologous Breast Reconstruction: A National Analysis of Clinical and Financial Outcomes.","authors":"Nisha Gupta, Yasmine Ibrahim, Emili Elkins, Alberto R Valenzuela, Nikhil L Chervu, Saad Mallick, Peyman Benharash, Michael R DeLong","doi":"10.1055/a-2737-5205","DOIUrl":"10.1055/a-2737-5205","url":null,"abstract":"<p><strong>Background: </strong>Autologous breast reconstruction (ABR) is a reliable option for reconstruction after mastectomy. In cases where single donor sites do not offer adequate tissue, the use of \"stacked\" flaps, or multiple free flaps, can be brought together to provide optimal breast volume. This large-scale study aims to compare clinical outcomes, resource utilization, and readmission rates between single and stacked flaps.</p><p><strong>Methods: </strong>The National Readmission Database was used to retrospectively identify adult female patients who underwent ABR with free flaps between 2016 and 2020. In this study, free flaps were restricted to nonpedicled types, with latissimus dorsi (LD) and pedicled transverse rectus abdominis myocutaneous flaps (TRAM) excluded. Patients were categorized based on flap type (single vs. stacked) using relevant International Classification of Diseases, Tenth Edition (ICD-10) procedure codes. Patient demographics, hospital factors, complication rates, and readmission data were analyzed. The primary outcome was the difference in postoperative flap complication rates between single and stacked flaps.</p><p><strong>Results: </strong>A total of 52,180 adult females were included for analysis. Of these, 51,140 (<i>n</i> = 98.5%) had single flaps and 783 patients (<i>n</i> = 1.5%) had stacked flaps. Use of stacked flaps was not statistically associated with higher odds of any flap complication (adjusted odds ratios: 1.16, <i>p</i> = 0.46) compared to single flaps. Stacked flaps were associated with longer length of stay and higher hospitalization costs, but there was no significant difference in 30-day readmission compared to the single flap cohort.</p><p><strong>Conclusion: </strong>Our study found similar rates of overall flap complications between the cohorts. Thus, in cases where more tissue is needed or desired, the use of stacked flaps appears to be a safe and feasible option to ABR.</p>","PeriodicalId":16949,"journal":{"name":"Journal of reconstructive microsurgery","volume":" ","pages":"780-786"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145452344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Nerve Tape-Assisted PEG Fusion in a Rabbit Tibial Nerve Repair Model. 神经带辅助PEG融合在兔胫骨神经修复模型中的应用效果。
IF 2.3 3区 医学
Journal of reconstructive microsurgery Pub Date : 2026-11-01 Epub Date: 2025-11-05 DOI: 10.1055/a-2737-5393
Jonathan Isaacs, Geetanjali Bendale, Charles Reiter, Kush Savsani, Ananya Gomatam, Kenny Phan
{"title":"Efficacy of Nerve Tape-Assisted PEG Fusion in a Rabbit Tibial Nerve Repair Model.","authors":"Jonathan Isaacs, Geetanjali Bendale, Charles Reiter, Kush Savsani, Ananya Gomatam, Kenny Phan","doi":"10.1055/a-2737-5393","DOIUrl":"10.1055/a-2737-5393","url":null,"abstract":"<p><strong>Background: </strong>Polyethylene glycol (PEG) hydrogel is capable of fusing transected axons and restoring axonal continuity. The technique requires precise nerve coaptation alignment and stability, which is difficult to achieve utilizing conventional microsuture neurorrhaphy. Nerve Tape (NT) is a microhook-based nerve coaptation device engineered to facilitate stable and accurate nerve end alignment. The primary objective was to modify and validate NT-assisted PEG fusion using a rabbit proximal tibial nerve repair model at an intermediate time point.</p><p><strong>Methods: </strong>Three groups of rabbits underwent mid-thigh tibial nerve transection and immediate repair with NT + PEG (<i>n</i> = 6), Suture + PEG (<i>n</i> = 6), or Suture only (<i>n</i> = 6). PEG-induced axonal fusion was acutely confirmed via demonstration of compound motor action potential (CMAP) restoration. Final outcome testing at 16 weeks included electrodiagnostic testing, nerve histomorphology, and muscle morphology.</p><p><strong>Results: </strong>All 18 animals demonstrated immediate restoration of CMAPs. At 16 weeks, there were no statistical differences in nerve conduction velocity or amplitude, no statistical differences between groups in axon counts or g-ratios either near the nerve coaptations or at the ankle, and no differences in normalized gastrocnemius weight or girth.</p><p><strong>Conclusion: </strong>PEG fusion did not improve nerve regeneration or functional recovery in a rabbit tibial nerve repair model at 16 weeks. Modified NT did not improve the reliability or efficacy of the PEG fusion process compared with microsuture neurorrhaphy.</p>","PeriodicalId":16949,"journal":{"name":"Journal of reconstructive microsurgery","volume":" ","pages":"787-794"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145452280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Intersaphenous Veins in the Leg: Anatomical Considerations. 腿的隐静脉:解剖学上的考虑。
IF 2.3 3区 医学
Journal of reconstructive microsurgery Pub Date : 2026-11-01 Epub Date: 2025-11-19 DOI: 10.1055/a-2737-6384
Adam Sedlák, Michaela Veselá, David Kachlík
{"title":"The Intersaphenous Veins in the Leg: Anatomical Considerations.","authors":"Adam Sedlák, Michaela Veselá, David Kachlík","doi":"10.1055/a-2737-6384","DOIUrl":"10.1055/a-2737-6384","url":null,"abstract":"<p><strong>Background: </strong>The intersaphenous veins are inconstant veins interconnecting the great and the small saphenous veins. Due to the inclination of the superficial venous system to be rather inconsistent, this topic has never been described thoroughly and adequately before. The aim of our research was to observe intersaphenous veins and give a profound description of their variable anatomy.</p><p><strong>Methods: </strong>Sixty-three body donor limbs of Central European origin embalmed in formaldehyde were dissected. The tips of the medial and lateral malleoli were selected as suitable points of reference for measurements on the vertical axis of the leg. Additionally, each fibula was measured and related to the average length of the fibula in our examined sample. Consequently, each measurement was recalculated by this coefficient.</p><p><strong>Results: </strong>Five types of arrangement were described: no connection (22.22%), one connection (46.03%), two connections (19.05%), three connections (11.11%), and four connections (1.59%). The average point of communication between the great saphenous vein and the intersaphenous vein was located 21.50 ± 9.64 cm proximal to the medial malleolus and between the small saphenous vein and the intersaphenous vein, 18.45 ± 6.05 cm proximal to the lateral malleolus. Multiple heatmaps were created for an easier comprehension of the topic.</p><p><strong>Conclusion: </strong>This research provides a detailed anatomy of intersaphenous veins of the leg. Yet variable in their arrangement, intersaphenous veins were found in the majority of investigated limbs. Thanks to their favorable anatomy, intersaphenous veins offer new alternatives to the traditional venous grafts from the saphenous veins, not only for heart bypasses.</p>","PeriodicalId":16949,"journal":{"name":"Journal of reconstructive microsurgery","volume":" ","pages":"843-853"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145557106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rethinking Dangling: Omission of Inpatient Dangle Protocols Shortens Hospital Stay Without Adverse Effects on Lower Extremity Flap Outcomes. 重新思考悬吊:住院病人悬吊方案的遗漏缩短了住院时间而没有不良影响下肢皮瓣的预后。
IF 2.3 3区 医学
Journal of reconstructive microsurgery Pub Date : 2026-11-01 Epub Date: 2025-11-05 DOI: 10.1055/a-2737-5482
Michael I Kim, Katie A Shen, Claire Olivas, Eloise W Stanton, Jennifer Yoon, Jasmine Jin, Joseph N Carey, David A Daar, Emma C Koesters
{"title":"Rethinking Dangling: Omission of Inpatient Dangle Protocols Shortens Hospital Stay Without Adverse Effects on Lower Extremity Flap Outcomes.","authors":"Michael I Kim, Katie A Shen, Claire Olivas, Eloise W Stanton, Jennifer Yoon, Jasmine Jin, Joseph N Carey, David A Daar, Emma C Koesters","doi":"10.1055/a-2737-5482","DOIUrl":"10.1055/a-2737-5482","url":null,"abstract":"<p><strong>Background: </strong>Formal dangling protocols are often used after lower extremity free flap reconstruction to acclimate flaps to gravitational stress. However, their clinical benefit remains uncertain. This study evaluates how the inclusion or omission of structured inpatient dangling affects flap outcomes.</p><p><strong>Methods: </strong>A retrospective review was conducted of 82 patients who underwent lower extremity free flap reconstruction at a single institution (2015-2024). Patients were grouped based on use of a formal dangling protocol (≥3 consecutive supervised sessions beginning after postoperative day 5) versus no protocol (ad libitum dangling beginning day 3). Outcomes included flap survival, complications, 30-day unplanned reoperation, time to ambulation, and length of stay. Statistical analysis included chi-squared, <i>t</i>-tests, and multivariable regression models.</p><p><strong>Results: </strong>Fifty-three patients adhered to a dangle protocol; 29 did not follow a protocol. Demographics, comorbidities, flap type, and defect characteristics were similar between groups. Flap survival (96.2% vs. 96.6%, <i>p</i> = 0.94), partial necrosis (9.4% vs. 10.3%, <i>p</i> = 0.89), and reoperation rates (3.4% vs. 7.5%, <i>p</i> = 0.46) were comparable. On multivariable analysis, dangle protocol use was not associated with reduced complication risk (OR = 0.95, <i>p</i> = 0.93) but was associated with a 3.0-day longer median hospital stay (<i>p</i> < 0.01).</p><p><strong>Conclusion: </strong>The application of a formal dangling protocol did not affect flap survival but was independently associated with prolonged hospitalization. These findings challenge the necessity of structured regimens and support more patient-tailored postoperative strategies that may accelerate recovery without compromising surgical outcomes.</p>","PeriodicalId":16949,"journal":{"name":"Journal of reconstructive microsurgery","volume":" ","pages":"818-824"},"PeriodicalIF":2.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145452324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书