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Transluminal endoscopic surgery for bladder sphincter incompetence in female dogs 经腔内内镜手术治疗雌犬膀胱括约肌功能不全
Russian veterinary journal Pub Date : 2023-03-27 DOI: 10.32416/2500-4379-2023-1-34-45
A. Chernov, A. Lukomskiy, Azat Haerttinov, E. Agapov, Mariya Ivanova
{"title":"Transluminal endoscopic surgery for bladder sphincter incompetence in female dogs","authors":"A. Chernov, A. Lukomskiy, Azat Haerttinov, E. Agapov, Mariya Ivanova","doi":"10.32416/2500-4379-2023-1-34-45","DOIUrl":"https://doi.org/10.32416/2500-4379-2023-1-34-45","url":null,"abstract":"The article presents a step-by-step algorithm of a unique patented technique for the treatment of urinary incontinence - hormone-associated sphincter insufficiency in female dogs. \u0000The result was traced on 51 animals. The peculiarity of this technique is to perform the entire operation through the urethra, without percutaneous accesses. It is also noted that despite the existing prototypes, briefly described in foreign sources, the authors of the described method, patented in the territory of the Russian Federation, managed to find a unique and effective formula for performing the procedure. This approach, in which you can not worry about complications (which were not found in the sample described), allows you to conclude about a new approach to solving the \"old\" problem.","PeriodicalId":169474,"journal":{"name":"Russian veterinary journal","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116588555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The first experience of application of the drug «Coronaket» containing GS-441524 against feline infectious peritonitis 首次应用含有GS-441524的药物“Coronaket”治疗猫传染性腹膜炎
Russian veterinary journal Pub Date : 2023-03-27 DOI: 10.32416/2500-4379-2023-1-19-23
O. Gorbunova, O. Muracheva
{"title":"The first experience of application of the drug «Coronaket» containing GS-441524 against feline infectious peritonitis","authors":"O. Gorbunova, O. Muracheva","doi":"10.32416/2500-4379-2023-1-19-23","DOIUrl":"https://doi.org/10.32416/2500-4379-2023-1-19-23","url":null,"abstract":"Feline infectious peritonitis until recently, due to the lack of etiotropic therapy, was considered an incurable disease with a 99% fatal outcome. One of the most effective agents was the nucleoside analogue GS-441524, developed by Gilead Sciences. Until recently, preparations containing GS-441524 were typically manufactured in China and were not licensed. «Coronacat» is the first registered drug with a certificate manufactured by a GMP facility in Europe for the treatment of feline infectious peritonitis (developer by VETUCHASTOK LLC, manufacturer ‒ Promvetservice-Alba branch of Promvetservis LLC). The article describes the results of evaluating the efficacy and safety of «Coronacat» in feline viral peritonitis. 1 ml of the preparation contains 10 mg of nucleoside GS-441524. The object of the study was 20 cats aged 6 months to 5 years with infectious peritonitis. Cats were divided into 2 groups: 10 animals in the experimental group (using the test drug) and 10 animals in the historical control group (without the use of the test drug, based on archival data). The effectiveness of treatment was assessed according to the following criteria: 1) survival (life expectancy when studying the effectiveness of treatment methods); 2) the presence of adverse reactions to drugs; 3) for the experimental group - a change in the parameters of blood electrophoresis. The data obtained indicate that the «Coronacat» preparation based on the nucleoside GS-441524, in contrast to the standard treatment regimen, showed high efficiency in the treatment of feline viral peritonitis. The course of «Coronacat» is 84 injections (1 time per day), if necessary, treatment can be extended. The decision on the need to extend the course of «Coronacat» should be made by the animal's attending physician.","PeriodicalId":169474,"journal":{"name":"Russian veterinary journal","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127600431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tolerance study of ExpressTabs for dogs expresstab对犬的耐受性研究
Russian veterinary journal Pub Date : 2023-03-27 DOI: 10.32416/2500-4379-2023-1-29-33
Syergyey YEngashyev, E. Engasheva, Denis A. Novikov, A. Nikanorova, A. Mironenko
{"title":"Tolerance study of ExpressTabs for dogs","authors":"Syergyey YEngashyev, E. Engasheva, Denis A. Novikov, A. Nikanorova, A. Mironenko","doi":"10.32416/2500-4379-2023-1-29-33","DOIUrl":"https://doi.org/10.32416/2500-4379-2023-1-29-33","url":null,"abstract":"Parasitic diseases of dogs remain quite common throughout the Russian Federation, which creates the need for constant monitoring, prevention and treatment. \u0000The drug ExpressTabs developed by NVC Agrovetzashchita LLC is complex and multicomponent. Available in four modifications containing as active ingredients: spinosad, praziquantel, moxidectin and excipients. \u0000The aim of the study was to study the tolerability of ExpressTabs with its repeated daily use for 5 days in dogs at therapeutic and double therapeutic doses. \u0000Materials and methods. To study the tolerance of ExpressTabs, 3 groups of dogs were formed, 10 animals each (2 experimental and 1 control), (outbred individuals, average weight 23 kg.) \u0000Results and conclusions. The conducted studies allow us to conclude that daily multiple oral administration of the drug for 5 days to dogs in a therapeutic dose does not adversely affect the general condition of the animals, does not change the body temperature, morphological composition and biochemical parameters of the blood of animals. \u0000Repeated administration of the drug to dogs at a twice increased therapeutic dose daily for 5 days in 30% of cases has a toxic effect, expressed by signs of poisoning, which completely disappear without medical intervention within 24…48 hours. \u0000Based on the results of the conducted studies, it can be concluded that the drug ExpressTabs for dogs is safe when administered in therapeutic doses.","PeriodicalId":169474,"journal":{"name":"Russian veterinary journal","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122243600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study of the tolerance of the insecticide drops BARS® for cats 猫对BARS®杀虫剂滴剂的耐受性研究
Russian veterinary journal Pub Date : 2023-03-27 DOI: 10.32416/2500-4379-2023-1-24-28
Syergyey YEngashyev, Denis A. Novikov, A. Mironenko
{"title":"Study of the tolerance of the insecticide drops BARS® for cats","authors":"Syergyey YEngashyev, Denis A. Novikov, A. Mironenko","doi":"10.32416/2500-4379-2023-1-24-28","DOIUrl":"https://doi.org/10.32416/2500-4379-2023-1-24-28","url":null,"abstract":"Ectoparasites are a serious problem for veterinarians and pet owners. \u0000Insectoacaricidal preparation BARS®, developed by NVC Agrovetzashchita LLC, is a multicomponent insectoacaricide and is produced in the form of drops at the withers. For cats as active substances in 1 ml contains: fipronil ‒ 100 mg, cyfluthrin ‒ 2.5 mg, piperonyl butoxide ‒ 0.5 mg, diflubenzuron ‒ 1 mg. \u0000Purpose of the study. To study the tolerability of the drug during its repeated use in cats at a therapeutic dose of 0.5 ml/5 kg and a double therapeutic dose of 1 ml/5 kg of body weight with daily skin application for 7 days. \u0000 \u0000Materials and methods. To study the tolerability of the Insectoacaricidal preparation BARS®, 3 groups of cats were formed, 10 animals each (2 experimental and 1 control). \u0000Results. During the experiment, there were no external signs of intoxication in cats. All animals of the experimental groups were active. The reaction to external stimuli is preserved. The body temperature of the animals throughout the experiment remained within the physiological range in all groups. \u0000Conclusion. The drug in recommended doses is well tolerated by cats, does not adversely affect the general physiological state, morphological and biochemical parameters of blood, and physical and chemical parameters of urine. Also, they do not have a skin-resorptive and locally irritating effect.","PeriodicalId":169474,"journal":{"name":"Russian veterinary journal","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132150143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tests as a control of knowledge and a key link in improving the educational process 考试是对知识的控制，是改进教育过程的关键环节
Russian veterinary journal Pub Date : 2023-03-27 DOI: 10.32416/2500-4379-2023-1-7-9
R. Akbaev, N. Babichev
{"title":"Tests as a control of knowledge and a key link in improving the educational process","authors":"R. Akbaev, N. Babichev","doi":"10.32416/2500-4379-2023-1-7-9","DOIUrl":"https://doi.org/10.32416/2500-4379-2023-1-7-9","url":null,"abstract":"Testing is one of the modern forms of control and self-control of students' knowledge. In addition, testing reduces the subjectivity of teachers in assessing students' knowledge. Testing has the goal of optimizing the educational process and quality control of specialist training.","PeriodicalId":169474,"journal":{"name":"Russian veterinary journal","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114095718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Toxicological characteristics of a new drug Express Uspokoin® tablets for situational correction of behavioral abnormalities in cats and dogs 用于猫狗行为异常情境矫正的新药Express Uspokoin®片的毒理学特征
Russian veterinary journal Pub Date : 2023-03-27 DOI: 10.32416/2500-4379-2023-1-10-18
V. Orobec, D. Beloglazov, S. Mukaseev, O. Zeynalov
{"title":"Toxicological characteristics of a new drug Express Uspokoin® tablets for situational correction of behavioral abnormalities in cats and dogs","authors":"V. Orobec, D. Beloglazov, S. Mukaseev, O. Zeynalov","doi":"10.32416/2500-4379-2023-1-10-18","DOIUrl":"https://doi.org/10.32416/2500-4379-2023-1-10-18","url":null,"abstract":"Trazodone is a selective antagonist and serotonin reuptake inhibitor used in medicine to treat anxiety. Toxicological studies of trazodone succinate were carried out on the basis of the Department of Pharmacology of the Veterinary Faculty Stavropol State Agrarian University, Russia. \u0000The results obtained in the study of acute toxicity of the drug Express Uspokoin® tablets allow us to identify the new drug as belonging to moderately dangerous substances for mammals. \u0000When studying the subchronic toxicity of the drug in rats, it was found that its use for 90 days at doses 10...50 times higher than the therapeutic one does not cause changes in the clinical condition of experimental rats. \u0000The totality of the experimental data obtained unambiguously confirms the good tolerability of the drug Express Uspokoin® tablets. \u0000As a result of toxicological studies, it was found that the drug does not exhibit irritating and allergizing effects.","PeriodicalId":169474,"journal":{"name":"Russian veterinary journal","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126523014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Topical hormonal preparations ― convenience instead of safety 局部激素制剂-方便而不是安全
Russian veterinary journal Pub Date : 2022-09-28 DOI: 10.32416/2500-4379-2022-3-4-26-30
V. Andryushina, Vera Yaderec
{"title":"Topical hormonal preparations ― convenience instead of safety","authors":"V. Andryushina, Vera Yaderec","doi":"10.32416/2500-4379-2022-3-4-26-30","DOIUrl":"https://doi.org/10.32416/2500-4379-2022-3-4-26-30","url":null,"abstract":"The article examines the practice of unfair attitude of manufacturers of veterinary drugs to safety checks for both target animals and the environment. The reason for the release of unsafe drugs is commercial interest and the «human factor», which consists in a clear weakening of attention to the quality of research and responsibility for the results obtained by many domestic developers. As an example, the veterinary drug «Sex Control spot-on» for the regulation of sexual hunting in cats is considered. The general disadvantages of this dosage form are of particular importance due to its external method of application and a specific composition, including highly active steroid hormones, including skin-resorptive properties, the ingress of which into the external environment is unsafe for all mammals.","PeriodicalId":169474,"journal":{"name":"Russian veterinary journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128839118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adaptation of pets to new living conditions 使宠物适应新的生活环境
Russian veterinary journal Pub Date : 2022-09-28 DOI: 10.32416/2500-4379-2022-3-4-15-18
Dar'ya Lesnikova
{"title":"Adaptation of pets to new living conditions","authors":"Dar'ya Lesnikova","doi":"10.32416/2500-4379-2022-3-4-15-18","DOIUrl":"https://doi.org/10.32416/2500-4379-2022-3-4-15-18","url":null,"abstract":"The paper presents the results of studies of hematological parameters of dogs and cats when adapting to new living conditions. It was revealed that the change of residence for small pets causes a number of changes in the blood composition, which can be considered as a reaction to stress when adapting to new living conditions.","PeriodicalId":169474,"journal":{"name":"Russian veterinary journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129589799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hereditary hyperlipidemia ocular lesions in a decorative domestic rabbit 家兔遗传性高脂血症眼部病变
Russian veterinary journal Pub Date : 2022-09-28 DOI: 10.32416/2500-4379-2022-3-4-37-52
Yuliya S. Artyushina
{"title":"Hereditary hyperlipidemia ocular lesions in a decorative domestic rabbit","authors":"Yuliya S. Artyushina","doi":"10.32416/2500-4379-2022-3-4-37-52","DOIUrl":"https://doi.org/10.32416/2500-4379-2022-3-4-37-52","url":null,"abstract":"In animals, as in humans, a significant part of the functional or morphological ophthalmic pathologies are associated with general or systemic diseases. Abnormalities detected during ophthalmological examination, in some cases, are symptoms of a general pathological process and can contribute to the diagnosis. The article discusses the clinical case of the eye pathological changes development in a decorative domestic rabbit (Oryctolagus cuniculus domesticus) accompanying a cholesterol metabolism hereditary disorder: chronic lipogranulomatous conjunctivitis, lipid degeneration of the cornea, massive cholesterol infiltration of the sclera fibrous stroma and eyeball posterior pole, hypertrophy of the orbit fatty cellular tissue. The observed pathological processes in the eyes and their adnexal structures were manifestated severely. The article presents MRI data and photographs of histological preparations of pathologically altered tissues. A clinical description of severe ophthalmic abnormalities in rabbit with hereditary hyperlipidemia as in our article, is not presented in the available scientific literature.","PeriodicalId":169474,"journal":{"name":"Russian veterinary journal","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133177947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of a preventive efficacy for a new anthelminthic drug Supramil® tablets regarding heartworm disease in dogs 一种新的驱虫药物Supramil®片对犬心丝虫病的预防效果评价
Russian veterinary journal Pub Date : 2022-09-28 DOI: 10.32416/2500-4379-2022-3-4-31-35
A. Shinkarenko, Konstantin Kamenov, S. Mukaseev, O. Zeynalov
{"title":"Evaluation of a preventive efficacy for a new anthelminthic drug Supramil® tablets regarding heartworm disease in dogs","authors":"A. Shinkarenko, Konstantin Kamenov, S. Mukaseev, O. Zeynalov","doi":"10.32416/2500-4379-2022-3-4-31-35","DOIUrl":"https://doi.org/10.32416/2500-4379-2022-3-4-31-35","url":null,"abstract":"There was studied an effectiveness of the new anthelmintic drug Supramil® tablets for prevention of dirofilariasis in dogs. With a monthly treatment of dogs free from larvae of Dirofilaria spp. with the drug Supramil® tablets, used at dose of 0.5 mg / kg on a body weight according to milbemycin oxime, in a region unfavorable for dirofilariasis, the preventive effectiveness of the drug was 100 %. \u0000Monthly control of microfilariaemia, carried out before each drug treatment, showed an absence of larvae of Dirofilaria spp. in peripheral blood of 100% of experimental animals, which indicates not only high preventive efficacy of the drug, but also its prolonged microfilaricidal action and a possibility to use it for prevention of dirofilariasis with an interval of 28…35 days. \u0000Thus, Supramil® tablets are highly effective to prevent dirofilariasis in disadvantaged regions.","PeriodicalId":169474,"journal":{"name":"Russian veterinary journal","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114213672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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