INDIAN JOURNAL OF AYURVEDA & INTEGRATIVE MEDICINE KLEU最新文献

{"title":"Integration of Rasayana therapy with chemotherapy improved therapeutic outcomes in a geriatric advanced nonresponsive pancreatic cancer patient - A case report","authors":"Y. Bendale, Poonam Birari-Gawande, A. Patil, A. Kadam","doi":"10.4103/ijaim.ijaim_39_22","DOIUrl":"https://doi.org/10.4103/ijaim.ijaim_39_22","url":null,"abstract":"Pancreatic cancer carries one of the most dismal prognoses. In patients, who are inoperable, the main objectives of palliation are relief from obstructive jaundice, prevention or respite from gastrointestinal obstruction, and management of pain. In the present case, the patient has not shown a satisfactory response to chemotherapy, and therefore, opted Ayurveda as integrative medicine. The treatment was initiated with herbo-mineral Rasayana formulations along with chemotherapy. These therapies have significantly reduced the symptoms in the patient and also improved the quality of life (QoL). Besides improving the QoL, this case demonstrates a very important finding that combination treatment with Rasayana therapy has the potential to cause regression of tumor metabolic activity in those patients who do not respond satisfactorily to cytotoxic regimens. Besides this, Rasayana therapy also helped in improving the health-related QoL, alleviating disease symptoms, as well as toxic manifestation of chemotherapy.","PeriodicalId":168535,"journal":{"name":"INDIAN JOURNAL OF AYURVEDA & INTEGRATIVE MEDICINE KLEU","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126836093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standardization of Bindu Pramana for Nasya","authors":"Aiswarya Balagopal, B. Sukumar","doi":"10.4103/ijaim.ijaim_3_23","DOIUrl":"https://doi.org/10.4103/ijaim.ijaim_3_23","url":null,"abstract":"Introduction: Nasya (nasal administration of medication) is one of Dinacharya (daily regimen) mentioned by Acharyas. Two Bindu is considered the recommended dose of Pratimarsha Nasya (done as a part of daily regimen). Bindu is defined as the total quantity of liquid medicine that dribbles down when the first two digits of index finger (distal and middle phalanges) are dipped into it and taken out of the same. Considering the above definition of Bindu, it is evident that Bindu Pramana varies from person to person probably due to the variation in size of one's index finger and also viscosity of the liquid used for Nasya. Materials and Methods: A total of 405 apparently healthy subjects with body mass index (BMI) between 18.5 and 24.9 kg/m2 coming under the age group of 18–60 years were selected. The subjects had to dip their index finger up to middle interphalangeal joint in Anu Taila, Tila Taila, and Sarshapa Taila one after the other. The whole amount of Taila (oil) that dripped down after dipping finger was collected in a watch glass and sucked into calibrated syringe for further calculations. Results: The Bindu Pramana for subjects with BMI range within 18.50–24.99 kg/m2 was found to be 0.55 ml (12.4 drops) for Tila Taila, 0.57 ml (12.4 drops) for Anu Taila, and 0.56 ml (11.8 drops) for Sarshapa Taila. Conclusion: This study of standardization of Bindu Pramana for Nasya concluded that Bindu Pramana for subjects with BMI range within 18.50–24.99 kg/m2 is 0.6 ml which is approximately 12 drops for all three Taila.","PeriodicalId":168535,"journal":{"name":"INDIAN JOURNAL OF AYURVEDA & INTEGRATIVE MEDICINE KLEU","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133688123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of autism spectrum disorder through Ayurveda - A case report","authors":"Masooda, V. Pathak, A. Mahapatra, Rajagopala Shrikrishna","doi":"10.4103/ijaim.ijaim_6_23","DOIUrl":"https://doi.org/10.4103/ijaim.ijaim_6_23","url":null,"abstract":"Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders marked by impairment in varying degrees of social communication and interaction, repetitive behaviors, and restricted interests. Based on clinical characteristics, ASD can be correlated with Unmada mentioned in Ayurveda classics. In clinical practice, there is a paucity of standard treatment protocols and effective care for the prevention of ASD. The present case report discusses a 5-year-old male patient who presented with poor eye contact, no communication, no social skills, poor speech, repetitive play activity, hyperactivity, constipation, and sleep disturbances reported at Kaumarabhritya outpatient department. Diagnosis of ASD was established using the Indian Scale for Assessment of Autism (ISAA) test manual. Abhyanga with Ksheerbala Taila and Nasya with Saraswata Ghrita along with other internal medications i.e., Saraswata Ghrita, Ashwagandharista, Guduchi Churna, Madhuyashthi Churna, and Vacha Churna were given. Remarkable improvement was noted in overall ISAA scores as well as clinical improvement noted in poor eye contact, hyperactivity, and peer relationship. “Child Sleep Habit Questionnaire (CSHQ)” was used to assess the child's sleep pattern and improvement was noted. The stress level of the parent also decreased which was assessed using the “Autism Parenting Stress Index.” No adverse effects were reported during the treatment period and follow-up.","PeriodicalId":168535,"journal":{"name":"INDIAN JOURNAL OF AYURVEDA & INTEGRATIVE MEDICINE KLEU","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129169916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of Unmada symptom checklist","authors":"Suchitra S. Patil, Ashutosh Kumar Singh, R. Nagarathna, H. Nagendra","doi":"10.4103/ijaim.ijaim_2_23","DOIUrl":"https://doi.org/10.4103/ijaim.ijaim_2_23","url":null,"abstract":"Background: Psychosis is explained as Unmada in Ayurveda Medical Science. Types of Unmada are based on Tridosha. General and a specific symptom of Unmada have been explained in classics exclusively. Unmada is alteration in mental functions such as behavior, emotions, intellect, memory, and character. The symptoms of Unmada are (1) Mano vibhrama - altered functions of mind, (2) Buddhi vibhrama - altered discriminative power, judgment, (3) Sanjañā jñāna vibhrama - altered consciousness, (4) Smriti vibhrama - confused memory, (5) Bhakti vibhrama - altered attachment or embellishment, (6) Śīla vibhrama - altered nature or disposition, (7) Cheshta vibhrama - altered motion or gesture, and (8) Ācāra vibhrama - altered custom or practice. Many scales such as the Brief Psychiatry Rating Scale (BPRS) and positive and negative symptom scale are available from the modern perceptive. According to the Ayurveda perceptive, Unmada-specific symptom scale to measure Tridosha in psychotic patients is available, but there is a need for a standard scale to measure general symptoms so that the treatment for behavior, emotions, intellect, and memory can be planned as per the derangement. Hence, this study has been taken. Aims and Objective: The objective of the study was to develop a simple, standardized instrument to assess symptoms of Unmada according to the Ayurveda concepts in the diagnosed patients of psychosis. Methods: This was a descriptive type of study to develop a scale. A 54-item, Unmada symptom checklist (USC) was developed based on symptoms description in Ayurvedic classics and by taking the opinions of experts (five Ayurvedic experts, five psychiatrists, and five psychologists). It was evaluated in 30 patients with the diagnosis of nonaffective psychosis to check the reliability of the instrument. Moreover, the scale was administered on 30 patients who were diagnosed with psychosis. The duration for administration was about 20–25 min. Results: The reliability of a USC was good which was supported by high internal consistency values of Cronbach's α – 0.9144. Correlation between total scores of BPRS and US was 0.959 and P<0.001, which was considered as statistically significant. Interrater reliability coefficient for each item ranged from 0.627 to 0.951. Correlation, which measures of criterion related validity, was 0.950 with BPRS, which suggested that Ayurveda concepts correlate with modern concepts. Conclusions: An USC is a simple, efficient, reliable, and valid instrument for clinicians to diagnose Unmada in patients according to the Ayurveda concept. However, further research with more number of samples, more diverse groups of psychotic disorders, and a broader range of convergent and discriminant validity are needed.","PeriodicalId":168535,"journal":{"name":"INDIAN JOURNAL OF AYURVEDA & INTEGRATIVE MEDICINE KLEU","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128165095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Ayurveda interventions in the management of primary hypothyroidism - A case report","authors":"Govardhan Belaguli, GM Brinda","doi":"10.4103/ijaim.ijaim_4_23","DOIUrl":"https://doi.org/10.4103/ijaim.ijaim_4_23","url":null,"abstract":"Hypothyroidism is a condition that lacks the release of thyroid hormone causing the opposition of the bodily tissues to the thyroid hormone in the view of metabolic demand. In Ayurveda, there is no exact linking term for hypothyroidism. The physiology and pathogenesis of oxidation and metabolism in each and every tissue of the body are served as chief functions by Agni (~a system concerned with digestion and metabolism) and Pittadosha (~a bodily humor). With the support of principles of Anukta Vyadhi (~unstated diseases) of Ayurveda, hypothyroidism can be diagnosed as Agni dushitajanya Rasapradoshaja vyadhi associated either with Vata, Pitta or Kapha dosha. The Ayurvedic management of hypothyroidism is to address the pathology at its root by regulating the affected immune system. A 25-year-old female student, who was a known case of hypothyroidism with polycystic ovarian syndrome (PCOS) since nearly 2 years, was successfully treated using the above principle. Her thyroid stimulating hormone (TSH) before the intervention was 6.12 μIU/ml. She was subjected to Langhana chikitsa (~depleting therapy) to correct her alleviated Pitta and Kapha Dosha. This chikitsa involved induction of Deepana-Pachana (~enhancers of digestion and metabolism), Snehapana (~therapeutic intake of medicated unctuous substance), and Vamana chikitsa (~therapeutic emesis). She attained 8 Vegas (~bouts) and was discharged with suitable Samshamana oushadhis (~palliative or discharge medications) and Samsarjana karma (~Post therapy dietetic regimen for revival). After completing 1 month of follow-up she is currently asymptomatic and her TSH level is 3.73 μIU/ml. The adoption of various classical principles of Ayurveda in diagnosing the case, the minimal intervention used and the significant results obtained motivated us to document the case. Although the present testimony is of a small sample, a plan on a large sampled pilot study on the current treatment model is intended.","PeriodicalId":168535,"journal":{"name":"INDIAN JOURNAL OF AYURVEDA & INTEGRATIVE MEDICINE KLEU","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128554966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ayurvedic management of Vicharchika (Lichen Simplex Chronicus) - A case report","authors":"Neelam Singh, A. Sengar, B. Khuntia","doi":"10.4103/ijaim.ijaim_9_23","DOIUrl":"https://doi.org/10.4103/ijaim.ijaim_9_23","url":null,"abstract":"Lichen simplex chronicus (LSC) consists of lichenified scaly plaque due to chronic scratching. The available conventional treatments are various topical antipruritic agents and corticosteroids, which are associated with high rates of treatment failure and complications because trans-epidermal drug absorption is limited. LSC manifests as a significant challenge to a physician due to persistent itching and therapeutic resistance. In Ayurveda, this condition has a close resemblance to Vicharchika. Vicharchika is a type of Kshudra kustha with dominancy of Kapha dosha characterized by redness, itching, pain, cracks, and dryness. In this case report, a 48 year old female reported complaints of multiple black-colored patches on the dorsum surface of bilateral feet with severe itching for 6 years. Local examination revealed lichenified hyperpigmented plaques with erythematous bases and well-defined edges covered by white scales with central excoriation. Plaques were found bilaterally over the dorsum of feet and malleolus. Based on symptoms and signs, the case of LSC was diagnosed. This case was managed effectively with Ayurvedic internal medications such as Arogyavardhini Vati, Kaishore Guggulu, Nishaamlaki Vati, Triphala churna, Khadirarishta, and local application of Brihat Marichyadi oil and Sudha Gandhak. The outcome assessment was based on improvement in the size of skin patches, hyperpigmentation, thickening, and itching. Complete improvement has been observed in symptoms after 4 months of regular treatment. No adverse effect pertaining to the prescribed drug was reported during the study period. Ayurvedic medicines offer a good approach to managing LSC.","PeriodicalId":168535,"journal":{"name":"INDIAN JOURNAL OF AYURVEDA & INTEGRATIVE MEDICINE KLEU","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127954670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing the rigor and reproducibility of review studies in Rasa Shastra and Bhaishajya Kalpana through standard vocabulary: A call to action","authors":"Galib, Anu Ruhila, CS Anjana","doi":"10.4103/ijaim.ijaim_16_23","DOIUrl":"https://doi.org/10.4103/ijaim.ijaim_16_23","url":null,"abstract":"","PeriodicalId":168535,"journal":{"name":"INDIAN JOURNAL OF AYURVEDA & INTEGRATIVE MEDICINE KLEU","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122405178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of ayurveda in the management of hypothyroidism - A case report","authors":"A. Kapoor, S. Raturi","doi":"10.4103/ijaim.ijaim_24_22","DOIUrl":"https://doi.org/10.4103/ijaim.ijaim_24_22","url":null,"abstract":"Compromised daily habits such as more sugar intake, lack of exercise, stress, familial tendencies, etc., lead to various lifestyle diseases impacting the normal functioning of the human body systems. Hypothyroidism is one such disease that is caused due to inadequate production of thyroid hormones. The thyroid gland regulates the body's metabolism and growth. In Ayurveda, this is attributed to a function of Agni. Clinical symptoms of this disease closely resemble Agnimandya and symptoms precipitated consequentially. A 24-year-old female patient visited the hospital with complaints of irregular menstruation, heaviness all over the body, gradual weight gain, and constipation. After thorough examination and investigations, she was diagnosed with a case of hypothyroidism with increased thyroid-stimulating hormone levels. Her ultrasound findings also showed a polycystic ovary syndrome-like presentation with mildly enlarged bilateral ovaries with multiple small follicles and increased ovarian stroma. She was effectively treated with an Ayurvedic treatment approach for 5 months (five cycles).","PeriodicalId":168535,"journal":{"name":"INDIAN JOURNAL OF AYURVEDA & INTEGRATIVE MEDICINE KLEU","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126846226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality assessment of market samples of ashokarishta: A polyherbal formulation","authors":"Soumya Fadnis, Rajeshwari Kamat","doi":"10.4103/ijaim.ijaim_18_22","DOIUrl":"https://doi.org/10.4103/ijaim.ijaim_18_22","url":null,"abstract":"Background: Ashokarista is an Ayurvedic herbal remedy with Ashoka as the main ingredient for rejuvenating the female reproductive system and blood. Because of the rapid commercialization of Ayurvedic products, assurances of their safety and efficacy have become critical. Therefore, to achieve this, the Ayurvedic Pharmacopoeia of India advocates the implementation of various Quality Control Parameters, such as Organoleptic Characters, Physico-chemical characteristics, Qualitative analysis, Quantitative analysis, and Microbial tests. Aim and Objective: To evaluate the quality standards of Ashokarishta's selected marketed samples. Materials and Methods: Quality control parameters such as organoleptic characteristics, physicochemical analysis, and microbial contamination studies were applied to all samples collected. Results: The current findings show that the samples differ in several analytical parameters. Conclusion: Sample A was found to be safe and had the highest concentration of gallic acid of the five samples tested.","PeriodicalId":168535,"journal":{"name":"INDIAN JOURNAL OF AYURVEDA & INTEGRATIVE MEDICINE KLEU","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114168541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of ashwagandhadi granules on physical performance in healthy individuals","authors":"N. Ashitha, B. Sukumar","doi":"10.4103/ijaim.ijaim_13_22","DOIUrl":"https://doi.org/10.4103/ijaim.ijaim_13_22","url":null,"abstract":"Introduction: Physical fitness is a state of health and well-being and more specifically, the ability to perform the aspects of sports, occupations, and daily activities. A higher fitness level indicates a better long-term effect of health. Physical fitness is generally achieved through a proper nutrition, moderate physical exercise, hygiene, and sufficient rest. Considering the nutritional aspect of physical fitness, supplements are required to bridge the nutritional gap due to busy work schedule and faulty food habits. Hence, a health supplement is the need for the hour which is tasty, will meet the daily requirements, and provide optimum nutrients for improving the physical fitness. Materials and Methods: Ashwagandhadi granules, formulated with a combination of food and Rasayana dravyas, consisting of Ashwagandha (Withania somnifera), Shatavari (Asparagus racemosus), Ragi (Eleusine coracana), Mudga (Vigna radiata), Jeeraka (E. coracana), and Shunti (Zingiber officinale), can be a promising health supplement. An open-label double-arm control clinical study with convenient sampling and modified wait-listed crossover design was conducted among 23 individuals. While in the study group, they were administered with 20 g of Ashwagandhadi granules with 150 ml milk for a month. Results: The result revealed a statistically significant change in the Harvard Step Score and VO2 max (z = 3.83, P < 0.001). Conclusion: The administration of Ashwagandhadi granules has a statistically significant effect on physical fitness.","PeriodicalId":168535,"journal":{"name":"INDIAN JOURNAL OF AYURVEDA & INTEGRATIVE MEDICINE KLEU","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114992251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}