New Advances in Brain & Critical Care最新文献

Exploring Pragmatic Deficits in Broca’s Aphasia Through Relevance Theory 通过相关性理论探索布罗卡失语症的语用缺陷

New Advances in Brain & Critical Care Pub Date : 2024-03-15 DOI: 10.33140/nabcc.05.01.01

{"title":"Exploring Pragmatic Deficits in Broca’s Aphasia Through Relevance Theory","authors":"","doi":"10.33140/nabcc.05.01.01","DOIUrl":"https://doi.org/10.33140/nabcc.05.01.01","url":null,"abstract":"This article delves into applying Sperber and Wilson’s Relevance Theory (2006) as a framework for comprehending language deficits in individuals diagnosed with Broca’s Aphasia. The theoretical foundation elucidates how communication difficulties characteristic of Broca’s Aphasia can be understood through optimizing relevance in discourse. It explores the efficacy of Relevance Theory in explicating the challenges faced by individuals with Broca’s Aphasia in expressing and processing linguistic information. Relevance Theory posits communication as a cognitive endeavor wherein speakers aim to maximize relevance, balancing cognitive effort and informational load. Methodologically, the study employs qualitative analysis of interactions between individuals with Broca’s Aphasia and interviewers. Using a corpus of three transcripts of language assessments retrieved from the Aphasia Bank database (MacWhinney et al., 2000), the research employs a qualitative linguistic analysis. Applying this framework to Broca’s Aphasia, characterized by expressive language impairments, offers insights into the pragmatic strategies employed by individuals to convey meaning. Findings underscore the benefits of employing Relevance Theory in elucidating language deficits, providing a better understanding of the pragmatic challenges faced by individuals with Broca’s Aphasia. However, the application of this theory also reveals challenges, particularly in accounting for the diverse and context-specific nature of language impairments within this population. In conclusion, the study advocates for the development of a specialized framework tailored to the unique language challenges inherent in Broca’s Aphasia.","PeriodicalId":168335,"journal":{"name":"New Advances in Brain & Critical Care","volume":"122 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140237980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Insidious Clinical-Radiological Features of Neuroinfectious Diseases in Emergency: A Clinical Case 急诊神经感染性疾病的阴险临床放射学特征：一个临床病例

New Advances in Brain & Critical Care Pub Date : 2023-10-31 DOI: 10.33140/nabcc.04.02.03

引用次数: 0

Dynamic Sets Set and Some of Their Applications to Neuroscience, Networks Set 动态集合及其在神经科学中的一些应用，网络集合

New Advances in Brain & Critical Care Pub Date : 2023-10-23 DOI: 10.33140/nabcc.04.02.02

引用次数: 0

A Case of Autosomal Recessive Dopa Responsive Dystonia (DRD) with GCH1 Gene Mutation 常染色体隐性多巴反应性肌张力障碍伴GCH1基因突变1例

New Advances in Brain & Critical Care Pub Date : 2023-06-16 DOI: 10.33140/nabcc.04.01.05

引用次数: 0

Can eraDOCator-60 Decrease MDRs and HAIs? An Evaluation of the Efficacy of eraDOCator-60 in a Randomized Clinical Trial in a Community Hospital. radocator -60能降低mdr和HAIs吗?一项社区医院随机临床试验评价根除因子-60的疗效。

New Advances in Brain & Critical Care Pub Date : 2023-06-03 DOI: 10.1101/2023.05.26.23290573

Martin Johns, Matthew Machata, RN StephanieLisenoMSN, Mba Fhm CPE. Joseph del Castillo MD

{"title":"Can eraDOCator-60 Decrease MDRs and HAIs? An Evaluation of the Efficacy of eraDOCator-60 in a Randomized Clinical Trial in a Community Hospital.","authors":"Martin Johns, Matthew Machata, RN StephanieLisenoMSN, Mba Fhm CPE. Joseph del Castillo MD","doi":"10.1101/2023.05.26.23290573","DOIUrl":"https://doi.org/10.1101/2023.05.26.23290573","url":null,"abstract":"ABSTRACT Background: There is a significant transmission of contaminants in the healthcare setting. Daily disinfection utilizing ammonium and chlorine-based products can lead to adverse health effects such as asthma, cancer, and other serious health issues. Methods: This study evaluated the effectiveness of eraDOCator-60 in a health care facility. This randomized trial took place at Copley Hospital in Morristown, Vermont. Separate areas of the hospital were cleaned and disinfected in one step with eraDOCator-60. A Charm analyzer was utilized to evaluate the efficacy of disinfection before and after 1 minute application of eraDOCator-60. The Charm analyzer detects Adenosine Triphosphate (ATP) presence measured in Relative Light Units (RLUs). Results: The median number of RLUs decreased from 52,874 s to 0 RLUs after one-minute eraDOCator-60 dwell time in the emergency room; 18.611 RLUs to 0 RLUs in the medical-surgical unit, 41,507 RLUs to 0 RLUs in the cafeteria; 24,932 RLUs to 0 RLUs in the birthing center. Conclusions: EraDOCator-60 reduced contamination levels on all surfaces in the acute care setting down to a value of zero following a 1-minute dwell time in less than 5% soil load. Keywords: Healthcare workers, infection prevention, healthcare associated infection prevention","PeriodicalId":168335,"journal":{"name":"New Advances in Brain & Critical Care","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130957147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-Amyloid-Β Monoclonal Antibodies against Alzheimer's Disease may be a Potential Breakthrough for Cataract Treatment 抗淀粉样蛋白-Β抗阿尔茨海默病单克隆抗体可能是白内障治疗的潜在突破

New Advances in Brain & Critical Care Pub Date : 2023-05-25 DOI: 10.33140/nabcc.04.01.02

引用次数: 0

Visual Cortical Neurons Depolarize after Hippocampal Ripples 海马波纹后视觉皮质神经元去极化

New Advances in Brain & Critical Care Pub Date : 2023-01-12 DOI: 10.33140/nabcc.04.01.01

引用次数: 0

Treating Spindling Excessive Beta with Inhibitory rTMS: A Case Study 抑制性rTMS治疗纺锤体过度β:个案研究

New Advances in Brain & Critical Care Pub Date : 2022-11-29 DOI: 10.33140/nabcc.03.01.04

引用次数: 0

Significance of Calorie-Restricted Ketogenic Diet for Lung Cancer with Brain Metastases and Hepatoma with Pulmonary Metastases: Two Case Reports 限制热量生酮饮食对肺癌合并脑转移和肝癌合并肺转移的意义:两例报告

New Advances in Brain & Critical Care Pub Date : 2022-01-17 DOI: 10.33140/nabcc.02.01.02

D. Tan, Jing Zhao, Wen-ru Yang, Fang Yuan

{"title":"Significance of Calorie-Restricted Ketogenic Diet for Lung Cancer with Brain Metastases and Hepatoma with Pulmonary Metastases: Two Case Reports","authors":"D. Tan, Jing Zhao, Wen-ru Yang, Fang Yuan","doi":"10.33140/nabcc.02.01.02","DOIUrl":"https://doi.org/10.33140/nabcc.02.01.02","url":null,"abstract":"Background: Cancer cells have altered metabolism that is characterized by an enhanced uptake and utilization of glucose. These increased glucose dependence alterations, present potential vulnerabilities that could be targeted for cancer therapy. The calorie-restricted ketogenic diet (KD) may meet the requirement. Case presentation: We present two cases of patients diagnosed with aggressive forms of cancer, lung cancer with brain metastatic tomours and primary liver cancer with pulmonary metastases. The patients began KD intervention after exhausting the other treatment options. Both of them responded to KD and demonstrated a beneficial effect. The tomour size from serial imaging and serum tumour markers were significantly reduced after KD in both subjects without any adverse effects. Both patients had tumour remission even after stopping the ketogenic diet, indicating that KD is a safe, effective treatment for aggressive cancers with metastases when used with conventional therapies. Conclusion: This study demonstrated the significant beneficial effect of a calorie-restricted ketogenic diet for two types of aggressive cancers with metastases. Even a brief KD intervention has a profound effect, implicating the significant therapeutic potential for the ketogenic diet as adjuvant therapy for cancer treatment.","PeriodicalId":168335,"journal":{"name":"New Advances in Brain & Critical Care","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114261206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anxiety, Depression, and The Burden of Caring for Patients with Palliative NeedsProspective Longitudinal Study 焦虑、抑郁和姑息治疗需求患者的护理负担:前瞻性纵向研究

New Advances in Brain & Critical Care Pub Date : 2022-01-17 DOI: 10.33140/nabcc.02.01.03

{"title":"Anxiety, Depression, and The Burden of Caring for Patients with Palliative NeedsProspective Longitudinal Study","authors":"","doi":"10.33140/nabcc.02.01.03","DOIUrl":"https://doi.org/10.33140/nabcc.02.01.03","url":null,"abstract":"Objectives: This study aims to measure the primary caregiver’s (PrC) anxiety, depression and burden of care and to identify the correlation between the outcomes. Material and Methods: This prospective observational longitudinal study assessed the burden of care for patients with palliative needs comparatively between two groups: caregivers of patients with cancer and caregivers of patients with non-malignant diseases. At the same time, the score of anxiety and depression of these caregivers was measured. The researcher used the Burden Scale for Family Caregivers (BSFC) to measure the burden of care and Hospital Anxiety and Depression Scale (HAD) to measure the anxiety and depression of primary caregivers. These questionnaires were applied at the initial moment (T0) and periodically for three months. If the patient died in this period, the caregivers were evaluated two months after the event. Statistical analysis used the Mann Whitney U test and the Wilcoxon test to compare the two groups and Pearson test to assess the correlation between burden and anxiety/ depression. Results: The burden assessment of caregivers for cancer patients showed a statistically significant increase over 3 months (p=0.001). At the initial moment (T0), a statistically significant difference is observed between the burden of the oncological group and the non-oncological one. The correlation between the caregiver's burden and anxiety/ depression was statistically significant (p = 0.001). Conclusions: The load had a direct and statistically significant impact on the PrC's psycho-emotional state, and there is a strong link between it and the caregiver's anxiety and sadness when caring for a palliative patient. From a practical point of view, it is important to early identify the burden of care and to know how the PrC is relating to it, as well as to assess his/her psycho-emotional state in order to act through appropriate and individualized interventions.","PeriodicalId":168335,"journal":{"name":"New Advances in Brain & Critical Care","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122596476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New Advances in Brain &amp; Critical Care最新文献

New Advances in Brain & Critical Care最新文献