Journal of Pharmaceutical and Scientific Innovation最新文献_第8页

AN OBSERVATIONAL EXPERIMENTAL ASSESSMENT OF ANTIBACTERIAL ACTIVITY OF GUDUCHI AGAINST KLEBSIELLA PNEUMONIAE BY URINE CULTURE AND SENSITIVITY IN PITTAJAMUTRAKRICHRA (URINARY TRACT INFECTION) 尿培养观察性实验评价古度菌对肺炎克雷伯菌的抑菌活性及对尿路感染皮氏杆菌的敏感性

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2020-01-25 DOI: 10.7897/2277-4572.091165

S. Anand, Ajantha, S. ShashirekhaK, Geetha Nayak

引用次数: 0

HPTLC FINGERPRINTING ANALYSIS OF SHILAJIT: AN AYURVEDIC HERBO-MINERAL DRUG 阿育吠陀草药矿物药希拉吉的hplc指纹图谱分析

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2019-09-10 DOI: 10.7897/2277-4572.085153

Binitha Raj Rv, S. Mahadevan, Rosa Mp, R. Ks

{"title":"HPTLC FINGERPRINTING ANALYSIS OF SHILAJIT: AN AYURVEDIC HERBO-MINERAL DRUG","authors":"Binitha Raj Rv, S. Mahadevan, Rosa Mp, R. Ks","doi":"10.7897/2277-4572.085153","DOIUrl":"https://doi.org/10.7897/2277-4572.085153","url":null,"abstract":"Introduction: Shilajit (Black bitumen: Asphaltum punjabinum) is an important herbo-mineral drug in Ayurvedic system of medicine. It is a blackish brown exudate which oozes out from sedimentary mountain rocks. Due to its high cost, increased demand and difficulty in getting pure forms, adulteration of shilajit is common in raw drug industry. So quality control parameters are necessary to scrutinize genuine shilajit. Objectives: The present work aims to develop simple quality control parameters of shilajit in terms of physicochemical properties and HPTLC (High Performance Thin Layer Chromatography) fingerprinting. Materials & Methods: Microscopic evaluation, flame test and organoleptic evaluation of shilajit were done to confirm the identity. Physico-chemical parameters such as specific gravity, pH, refractive index, loss on drying, total ash, acid-insoluble ash, solubility, fluorescence analysis and qualitative analysis were carried out. Moreover, HPTLC fingerprint was developed using Camag HPTLC instrument and detected its presence in a pharmaceutical preparation. Results: Physico-chemical parameters of shilajit were established and HPTLC chromatogram was developed with hydro-alcoholic extract of shilajit using the mobile phase Toluene: Ethyl acetate. This HPTLC method was also proved successful in confirming its presence in Chandraprabha gudika. Conclusion: The present study on identification, physico-chemical evaluation and HPTLC fingerprinting of shilajit provides useful information regarding quality control parameters and identifying parameters to substantiate and authenticate the drug and could be used for comparison of market samples to ensure its genuineness. A simple, specific and accurate HPTLC method was validated for its fingerprint analysis and detection in a pharmaceutical preparation, Chandraprabha gudika.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"329 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76567101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ROLE OF AYURVEDA DIETETICS IN THE MANAGEMENT OF MADHUMEHA (DIABETES MELLITUS): A REVIEW 阿育吠陀营养学在糖尿病治疗中的作用:综述

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2019-09-10 DOI: 10.7897/2277-4572.085150

S. Raj, Shivakumar

引用次数: 3

VIRTUAL SCREENING FOR IDENTIFICATION OF POTENT ANTI-ASTHMATIC COMPOUNDS EXTRACTED FROM THYME PLANT: IN-SILICO APPROACH 从百里香植物中提取的有效抗哮喘化合物的虚拟筛选鉴定:计算机方法

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2019-09-10 DOI: 10.7897/2277-4572.085154

A. A. A. Abdusalam, Gazala Mohamed Ben hander

引用次数: 1

JIHWA PAREEKSHA IN SAAMA AVASTHA OF AMLAPITTA: A CLINICAL STUDY

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2019-09-10 DOI: 10.7897/2277-4572.085149

B. Anuradha, Ajantha, S GeethaNayak, Anjana

{"title":"JIHWA PAREEKSHA IN SAAMA AVASTHA OF AMLAPITTA: A CLINICAL STUDY","authors":"B. Anuradha, Ajantha, S GeethaNayak, Anjana","doi":"10.7897/2277-4572.085149","DOIUrl":"https://doi.org/10.7897/2277-4572.085149","url":null,"abstract":"Ayurveda emphasizes agni-vaishamya as a cause of manifestation of vyadhi (disease). The undigested food due to vitiated agni results in apakwa-ahara-rasa, that does not get absorbed and transformed is termed as ama, is said to be root cause for diseases. Ama combines with dosha to form amadosha that acquires more shuktatva, further forming amavisha, paving to varied manifestations in diseases. Therefore, analyzing saama and niramavastha is essential for better diagnosis and management. Amlapitta, one among the annavaha-sroto-vikara manifests due to agni-vaishamya. Jihwa pareeksha (tongue examination) plays an important role to assess various changes in jihwa. It reflects the status of annavaha-srotas and ama. Thus, the present study aims at observation of manifestations on jihwa (tongue) by jihwa pareeksha in saama avastha of Amlapitta. Patients of Amlapitta were screened and subjected for jihwa pareeksha. Diagnosis of Amlapitta assessed by samanya lakshanas of Amlapitta and their saama avastha was evaluated by samanya lakshanas of Ama. From study, it is concluded that the manifestations elicited by jihwa pareeksha can be utilized for assessment of saama avastha in Amlapitta by clinical examination.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"129 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73431135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DEVELOPMENT AND VALIDATION OF Q-ABSORBANCE RATIO SPECTROPHOTOMETRIC METHOD FOR THE SIMULTANEOUS ESTIMATION OF RIFAMPICIN AND ITS BIOENHANCER; 3, 5'-DIHYDROXYFLAVONE-7-O-B-D-GALACTURONIDE-4'-O-B-D-GLUCOPYRANOSIDE; IN BULK AND FORMULATION q -吸收比分光光度法同时测定利福平及其生物增强剂含量的建立与验证3、5‘-DIHYDROXYFLAVONE-7-O-B-D-GALACTURONIDE-4 -O-B-D-GLUCOPYRANOSIDE;散装和配方

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2019-09-10 DOI: 10.7897/2277-4572.085152

S. Bhusari, S. Waghmare, P. Wakte

{"title":"DEVELOPMENT AND VALIDATION OF Q-ABSORBANCE RATIO SPECTROPHOTOMETRIC METHOD FOR THE SIMULTANEOUS ESTIMATION OF RIFAMPICIN AND ITS BIOENHANCER; 3, 5'-DIHYDROXYFLAVONE-7-O-B-D-GALACTURONIDE-4'-O-B-D-GLUCOPYRANOSIDE; IN BULK AND FORMULATION","authors":"S. Bhusari, S. Waghmare, P. Wakte","doi":"10.7897/2277-4572.085152","DOIUrl":"https://doi.org/10.7897/2277-4572.085152","url":null,"abstract":"The present research work demonstrates an analytical method development for simultaneous estimation of Rifampicin (RIF) and its bioenhancer; 3’,5dihydroxyflavone-7-O-β-D-galacturonide-4’-O-β-D-glucopyranoside (CC-I) in combined dosage form using Q-absorbance ratio concept. While method development, two different wavelengths one representing Iso-absorptive point (370 nm) and other representing the λmax of Rifampicin (239 nm) were used. Optimum response was obtained in solvent system that comprises methanol and water in ratio of 80:20 v/v. Proposed UV method was found to be linear over the concentration range of 2-20 μg/ml for Rifampicin and that of 1-24 μg/ml for CC-I. On the basis of recovery studies after standard addition, accuracy of proposed method was found to be in between 99.94 to 100.30 and 99.90 to 99.96 % for RIF and CC-I respectively. Intra-day precision of the method in terms of % relative standard deviation was found to be in between 0.21 to 1.36 and 0.21 to 1.77 for RIF and CC-I respectively. Inter-day precision range of the method for RIF and CC-I was found to be in between 0.13 to 1.94 and 0.11 to 1.58 respectively. LOD and LOQ of proposed UV method were 0.043 and 0.014 μg/ml for RIF and 0.37 and 0.12 μg/ml for CC-I. Proposed UV method was robust and rugged in nature. Proposed method was successfully used for the estimation of RIF and CC-I contents of in-house formulation consisting of APIs and the common excipients.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84001097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A COMPARATIVE STUDY TO EVALUATE EFFICACY OF GOKSHURA AND GUDUCHI AGAINST KLEBSIELLA PNEUMONIAE BY URINE CULTURE AND SENSITIVITY IN PITTAJA MUTRAKRICHRA (URINARY TRACT INFECTION) 通过尿培养及对尿路感染的敏感性比较评价果舒拉和古度齐对肺炎克雷伯菌的疗效

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2019-09-10 DOI: 10.7897/2277-4572.085148

S. Anand, Ajantha, S ShashirekhaK, B. Anuradha

引用次数: 0

PREVENTION OF STHOULYA (OBESITY) WITH AHARA AND VIHARA: A REVIEW hara和vihara预防肥胖的研究进展

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2019-09-10 DOI: 10.7897/2277-4572.085151

Aparajita Das, T. Tripathy

{"title":"PREVENTION OF STHOULYA (OBESITY) WITH AHARA AND VIHARA: A REVIEW","authors":"Aparajita Das, T. Tripathy","doi":"10.7897/2277-4572.085151","DOIUrl":"https://doi.org/10.7897/2277-4572.085151","url":null,"abstract":"Obesity is the common non communicable disease which is major public problem of 21th century. Obesity increase the other various diseases like type 2 Diabetes mellitus, Heart disease, certain type of cancer, sleep apnoea and osteoarthritis. In 2016 more than 1.9 billion adults aged 18 and older were overweight of which over 650 million were obese. This represents about 39% of adults with overweight and 13% of them obese. Considering the disease burden in India, according to National Family Health Survey 2007 it was estimated that 12.1 % of males and 16% of females were overweight or obese and in Karnataka it was 14% of males and 17.3% of females. Obesity one among lifestyle disorder hence proper ahara, vihara is essential in order to prevent it. In Ayurveda ahara (food) is mentioned as one among the trayauapastambha (three sub pillars of life) which supports the body. So food plays a major role to preventing diseases like obesity. Along with ahara improper vihara (life style) also plays a major role in incidence of obesity. Now a days due to sedentary lifestyle during domestic and occupational activities leading to lifestyle disorders like Obesity. So it is importance to stress on lifestyle modification. Present study highlights on role of diet and lifestyle modification in Obesity.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90149949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AN OVERVIEW ON HERBAL SUNSCREEN FORMULATION AND SUN PROTECTION FACTOR VALUE 草药防晒配方及防晒系数值综述

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2019-07-20 DOI: 10.7897/2277-4572.084141

M AshithaSaffrin, R. Sureshkumar

引用次数: 1

CRITICAL REVIEW ON RASAOUSHADI IN GERIATRICS WITH SPECIAL REFERENCE TO DEMENTIA rasaoushadi在老年病学中的应用综述，特别涉及痴呆

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2019-07-20 DOI: 10.7897/2277-4572.084146

A. Joshi, Rashmi Pujar, Pallavi Mullimani, A. Haridas

引用次数: 0