Journal of Pharmaceutical and Scientific Innovation最新文献_第2页

A REVIEW ON VAIKRUTAPAHA CHIKITSA IN THE MANAGEMENT OF VRANA (WOUND) 奇奇塔法在外伤治疗中的应用综述

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2021-12-30 DOI: 10.7897/2277-4572.106220

Y. H., Anand Katti

引用次数: 0

UTILITY OF SUDHA CHURNA IN AYURVEDA: A CRITICAL REVIEW sudha churna在阿育吠陀医学中的应用:综述

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2021-12-30 DOI: 10.7897/2277-4572.106222

Anand Rajaram Mirajakar, Anand Katti

引用次数: 0

FORMULATION AND EVALUATION OF SUSTAINED RELEASE MATRIX TABLET OF LORNOXICAM BY DIRECT COMPRESSION METHOD 直接压缩法氯诺昔康缓释片的研制及评价

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2021-10-31 DOI: 10.7897/2277-4572.105218

A. Pasha, C. Somashekhar

{"title":"FORMULATION AND EVALUATION OF SUSTAINED RELEASE MATRIX TABLET OF LORNOXICAM BY DIRECT COMPRESSION METHOD","authors":"A. Pasha, C. Somashekhar","doi":"10.7897/2277-4572.105218","DOIUrl":"https://doi.org/10.7897/2277-4572.105218","url":null,"abstract":"The aim of the present work was to develop sustained release Lornoxicam matrix tablets with polymers like HPMC K15M, Ethyl cellulose, and Crospovidone as carriers in varying quantities. Direct compression was used to make matrix tablets. Various assessment parameters, such as hardness, friability, thickness, percent drug content, weight variation, and so on, were applied to the prepared formulations. In vitro dissolution studies were carried out for 24 hrs. The tablets were subjected to in-vitro drug release in (pH 1.2) for first 2 hrs. Then followed by (pH 6.8) phosphate buffer for next 22 hrs. And the results showed that among the six formulations FL3 showed good dissolution profile to control the drug release respectively. The drug and polymer compatibility were tested using FT-IR spectroscopy, which revealed that the drug was compatible with all polymers. It is also required to design an appropriate prolonged release formulation for Lornoxicam in order to maintain the drug's release. Hence by using the compatible polymers sustained release tablets were formulated and subjected for various types of evaluation parameters like friability, hardness, drug content and dissolution behaviour. Finally, the findings reveal that the prepared sustained release matrix tablets of lornoxicam have improved efficacy and patient compliance.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84654117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AN EXPERIMENTAL STUDY TO EVALUATE THE HEPATOPROTECTIVE ACTIVITY OF NILITANDULIYADI LEHA IN PARACETAMOL INDUCED HEPATOTOXICITY IN WISTAR ALBINO RATS 目的探讨利利多利亚地对扑热息痛致白化大鼠肝毒性的保护作用

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2021-10-31 DOI: 10.7897/2277-4572.105217

Sreekala Vijayan, J. Kishore

{"title":"AN EXPERIMENTAL STUDY TO EVALUATE THE HEPATOPROTECTIVE ACTIVITY OF NILITANDULIYADI LEHA IN PARACETAMOL INDUCED HEPATOTOXICITY IN WISTAR ALBINO RATS","authors":"Sreekala Vijayan, J. Kishore","doi":"10.7897/2277-4572.105217","DOIUrl":"https://doi.org/10.7897/2277-4572.105217","url":null,"abstract":"Background: Paracetamol toxicity is currently the single most important cause for acute liver failure and is associated with significant number of deaths. Nilitanduliyadi leha is one among the formulation explained in the context of Vishahara yogas (anti-poisonous formulations) in the text Vishavaidya Jyotsnika. Objectives: To experimentally evaluate the hepatoprotective activity of nilitanduliyadi leha in paracetamol induced hepatotoxicity in Wistar albino rats. Methods: Albino Wistar rats of either sex weighing 200 – 250, g were selected and divided into four groups of six animals in each group (n = 6). Treatment was given for 7 days. Blood was drawn and sent for tests and important organs like liver and kidney were dissected out, cleaned to remove extraneous tissues, blotted to remove blood stain and weighed. A piece of liver tissue was preserved in 10% formalin for histopathological processing. Results: The formulation has helped in balancing the biochemical parameters studied almost as efficiently as the standard drug. In the antioxidant study also, the drug has given good results and shows even slightly more effective than the standard drug. The histopathology study also reveals mild protection and regeneration of tissues by the effect of test drug. Conclusion: This present study proves that the formulation is having a comparable hepato protective activity with that of silymarin.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84192443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ARKA LAVANA THE FORMULATION OF UPAVISHA ARKA (CALOTROPIS PROCERA AIT. R. BR.): AN ANALYTICAL PROFILE 山药的配方，山药的配方。R. br .):分析性的简介

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2021-08-23 DOI: 10.7897/2277-4572.104216

Chandankhede Aditi Vasudeorao, Anjankar Meghsham Pramodrao, Nikam Ashwin Vithalrao, Pawade Uday Venkatrao

引用次数: 0

KESHARANJANA YOGA IN BHAISHAJYA RATNAVALI: A REVIEW 《bhaishajya ratnavali》中的Kesharanjana瑜伽:综述

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2021-08-23 DOI: 10.7897/2277-4572.104213

D. Rakshitha, B. PallaviK, Gazala Hussain, Archana Pagad

{"title":"KESHARANJANA YOGA IN BHAISHAJYA RATNAVALI: A REVIEW","authors":"D. Rakshitha, B. PallaviK, Gazala Hussain, Archana Pagad","doi":"10.7897/2277-4572.104213","DOIUrl":"https://doi.org/10.7897/2277-4572.104213","url":null,"abstract":"Bhaishajya Ratnavali by Kaviraj Govinda Das Sen of 18th century is an authentic book of Ayurveda science includes systematic description of diseases along with treatment aspects. Under Kshudraroga Chikitsa Prakarana, detailed information regarding kesharanjana has been explained with description of kesharanjana yoga. This article mainly focuses on the kesharanjana yoga mentioned in this book for better nourishment and coloring of hair. Review on kesharanjana yoga mentioned in Bhaishajya Ratnavali was analyzed and summarized for better usage and understanding. Initially author explains few preparations to apply as lepa (application) over scalp or hairs and later nasya (inhalation therapy) procedure for hair care. Most of the drugs used are rasayana (immune modulator) in nature and has keshya (hair tonic) property which forms the prime factor in using these drugs. Direct application as lepa and also nasya procedure would help in better nourishment and also proper growth of hair. Owing to the properties of drugs used for the preparations which are useful in many conditions of hair problems. By following these yogas and with proper pathya one can get benefited from khalitya, palitya, and other conditions of hair.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74002308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

STANDARDIZATION OF SNUHI KSHARA THE FORMULATION OF UPAVISHA SNUHI (EUPHORBIA NERIIFOLIA LINN.): A PHARMACEUTICO-ANALYTICAL PROFILE 鼻烟壶的标准化。鼻烟壶(大戟)的配方:一种药物分析方法

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2021-08-23 DOI: 10.7897/2277-4572.104214

Asolkar Geeta Govindrao, Nikam Ashwin Vithalrao, Pawade Uday Venkatrao, Anjankar Meghsham Pramodrao

{"title":"STANDARDIZATION OF SNUHI KSHARA THE FORMULATION OF UPAVISHA SNUHI (EUPHORBIA NERIIFOLIA LINN.): A PHARMACEUTICO-ANALYTICAL PROFILE","authors":"Asolkar Geeta Govindrao, Nikam Ashwin Vithalrao, Pawade Uday Venkatrao, Anjankar Meghsham Pramodrao","doi":"10.7897/2277-4572.104214","DOIUrl":"https://doi.org/10.7897/2277-4572.104214","url":null,"abstract":"Snuhi (Euphorbia neriifolia Linn.) and its compound formulations are widely used in Ayurvedic classics to treat variety of disease conditions. Information pertaining to the formulations of Snuhi can be traced in various classical texts, under different chapters. In most of the formulations it is used as an ingredient. Snuhi Kshara is a single drug formulation of Upavisha Snuhi mentioned in Rasatarangini and Ayurvedsarasangraha. Kshara obtained from Snuhi is one of its dosage modifications, advocated in classics for therapeutic objectives. Very few attempts are made to formulate Snuhi Kshara. The present work has been carried out to provide the Standard Manufacturing Process and a systematic standardization profile for Snuhi Kshara. Snuhi Kshara was prepared according to procedure described in Sharangadhara Samhita followed by analytical standardisation. Standardization was done using guidelines of API, by employing tests like organoleptic (Colour, Odour, Taste), physicochemical (Loss on drying, Acid-insoluble ash, pH), Assay (Sodium, Potassium, Iron) and Thin Layer Chromatography. Findings of this work may enrich to documentary research as well as act as detailed scientific data about standardization of Snuhi Kshara for further studies.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83120883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

PHARMACEUTICO-ANALYTICAL PROFILE OF ARKA KSHARA THE FORMULATION OF UPAVISHA ARKA (CALOTROPIS PROCERA AIT. R. BR) 茴香的药物分析概况，茴香的配方。r . BR)

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2021-08-23 DOI: 10.7897/2277-4572.104215

Chandekar Deepali Boudhadas, Pawade Uday Venkatrao, Nikam Ashwin Vithalrao, Anjankar Meghsham Pramodrao

引用次数: 0

PREPARATION AND EVALUATION OF MEFENAMIC ACID AND DICYCLOMINE HYDROCHLORIDE AS ORAL DISINTEGRATING TABLET BY DIRECT COMPRESSION METHOD 直接压缩法制备甲氧胺酸盐酸二环胺口腔崩解片及评价

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2021-08-23 DOI: 10.7897/2277-4572.104211

T RanjithaM, C. Somashekhar

{"title":"PREPARATION AND EVALUATION OF MEFENAMIC ACID AND DICYCLOMINE HYDROCHLORIDE AS ORAL DISINTEGRATING TABLET BY DIRECT COMPRESSION METHOD","authors":"T RanjithaM, C. Somashekhar","doi":"10.7897/2277-4572.104211","DOIUrl":"https://doi.org/10.7897/2277-4572.104211","url":null,"abstract":"A new dosage form, Oral disintegrating tablets (ODT’s) as a replacement to conventional oral dosage forms. ODT’s are dosage forms they disintegrate in mouth offering various advantages such as better mouth feel, dose accuracy, improved stability and convenient dosing as compared to oral liquids. So, there is need to designed oral disintegrating tablet to release the medicaments with an enhanced rate. Mefenamic acid is an anti- inflammatory drug while Dicyclomine HCl is anti-cholinergic drug. The combination of Mefenamic acid & Dicyclomine HCl controls pain very effectively, also relaxes bodily spasm which commonly arises during menstruation or intestinal colic spasm. This combination gives the quick onset of action and fast relief than conventional dosage form. For preparation of oral disintegrating tablet nine formulations were designed using Croscarmellose sodium and Crospovidone as superdisintegrants in varying concentration. All the formulations were prepared by direct compression method. Thus, all the formulations of Mefenamic acid and Dicyclomine HCl oral disintegrating tablets were investigated, in which F9 formulation was optimized. The % drug release of, Oral disintegrating tablet batch F9 has shown 96.98% of Mefenamic acid and 94.02 % of Dicyclomine HCl in 18 min, disintegration time in 40 sec and wetting time in 25sec.","PeriodicalId":16738,"journal":{"name":"Journal of Pharmaceutical and Scientific Innovation","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77724520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EFFECT OF KSHEERBALA TAILA NASYA IN MIGRAINE WITH SPECIAL REFERENCE ARDHAVABHEDAK: A LITERARY REVIEW 藿香对偏头痛的治疗作用，附文献综述

Journal of Pharmaceutical and Scientific Innovation Pub Date : 2021-08-23 DOI: 10.7897/2277-4572.104212

Vitthal B. Bachate, Raman S. Belge

引用次数: 0