Journal of Patient-Centered Research and Reviews最新文献

{"title":"Partnering to Advance Health Equity and a Welcome Opportunity to Gather: Proceedings From the 28^th Annual Conference of the Health Care Systems Research Network.","authors":"Robert T Greenlee","doi":"10.17294/2330-0698.1994","DOIUrl":"10.17294/2330-0698.1994","url":null,"abstract":"<p><p>In April 2022, the Health Care Systems Research Network (HCSRN) - a consortium of 20 research institutions affiliated with large health systems spread across the United States (and one in Israel) - held its 28th annual conference in Pasadena, California, with 275 researchers, health care colleagues, and external academic partners in attendance. With a conference theme of \"Promoting Collaboration and Partnerships to Advance Health Equity,\" the scientific program was assembled by a multisite planning committee with input from representatives of informal local host Kaiser Permanente Southern California. Objectives of the annual conference are to showcase scientific findings from HCSRN projects and to spur collaboration on research initiatives that improve health and health care for individuals and populations. To those ends, the NIH Pragmatic Trials Collaboratory sponsored a preconference workshop on the essentials of embedded pragmatic clinical trials, and more than a dozen scientific interest groups and active research project teams held ancillary sessions throughout the conference. This welcome opportunity for network members to meet in-person followed a 2-year hiatus necessitated by the COVID-19 pandemic, during which HCSRN conference proceedings were conducted through virtual and written communication platforms.</p>","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"9 3","pages":"193-195"},"PeriodicalIF":1.6,"publicationDate":"2022-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302911/pdf/jpcrr-9.3.193.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40675667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abstracts From the 2022 Health Care Systems Research Network (HCSRN) Annual Conference.","authors":"","doi":"10.17294/2330-0698.1997","DOIUrl":"https://doi.org/10.17294/2330-0698.1997","url":null,"abstract":"s From the 2022 Health Care Systems Research Network (HCSRN) Annual Conference Follow this and additional works at: https://aah.org/jpcrr Part of the Diseases Commons, Health and Medical Administration Commons, Health Information Technology Commons, Health Services Research Commons, Medical Specialties Commons, Pharmacy and Pharmaceutical Sciences Commons, and the Psychiatry and Psychology Commons Recommended Citation Abstracts from the 2022 Health Care Systems Research Network (HCSRN) annual conference. J Patients from the 2022 Health Care Systems Research Network (HCSRN) annual conference. J Patient Cent Res Rev. 2022;9:196-245. doi: 10.17294/2330-0698.1997 Published quarterly by Midwest-based health system Advocate Aurora Health and indexed in PubMed Central, the Journal of Patient-Centered Research and Reviews (JPCRR) is an open access, peer-reviewed medical journal focused on disseminating scholarly works devoted to improving patient-centered care practices, health outcomes, and the patient experience.","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"9 3","pages":"196-245"},"PeriodicalIF":1.7,"publicationDate":"2022-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302906/pdf/jpcrr-9.3.196.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40675673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac Metastasis After Curative Treatment of Hepatocellular Carcinoma: Assessment of Risk Factors, Treatment Options, and Prognosis.","authors":"Gaurav Jain,&nbsp;Mathew Otto,&nbsp;Mubeen Khan Mohammed Abdul,&nbsp;Manpreet Chadha,&nbsp;Ajay Sahajpal","doi":"10.17294/2330-0698.1878","DOIUrl":"https://doi.org/10.17294/2330-0698.1878","url":null,"abstract":"<p><p>Hepatocellular carcinoma (HCC) is primary hepatic malignancy with a high incidence of recurrence. The risk of recurrence directly correlates to patient's overall prognosis. Management of advanced HCC involves a combination of surgical resection, locoregional therapy, and systemic treatment. Distant metastases are rare, and intraventricular cardiac metastases are even more infrequent. This brief review details an illustrative case of cardiac metastasis after curative treatment of primary HCC and then summarizes the literature on risk factors, treatment options, and patient prognosis in the setting of distant metastases from HCC. Prognosis of metastasis to the heart is generally poor, and available evidence emphasizes the importance of maintaining regular posttreatment screening for metastases in patients with HCC. Given the variable presentation and high risk of recurrence, it is critical to have individualized multimodality treatment plans.</p>","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"9 3","pages":"181-184"},"PeriodicalIF":1.7,"publicationDate":"2022-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302909/pdf/jpcrr-9.3.181.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40675668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-World Third COVID-19 Vaccine Dosing and Antibody Response in Patients With Hematologic Malignancies.","authors":"Michael A Thompson,&nbsp;Sigrun Hallmeyer,&nbsp;Veronica E Fitzpatrick,&nbsp;Yunqi Liao,&nbsp;Michael P Mullane,&nbsp;Stephen C Medlin,&nbsp;Kenneth Copeland,&nbsp;James L Weese","doi":"10.17294/2330-0698.1952","DOIUrl":"https://doi.org/10.17294/2330-0698.1952","url":null,"abstract":"Purpose This study sought to describe the changes in immune response to a third dose of either Pfizer's or Moderna's COVID-19 mRNA vaccine (3V) among patients with hematologic malignancies, as well as associated characteristics. Methods This retrospective cohort study analyzed pre-3V and post-3V data on 493 patients diagnosed with hematologic malignancies across a large Midwestern health system between August 28, 2021, and November 1, 2021. For antibody testing, S1 spike antigen of the SARS-CoV-2 virus titer was used to determine serostatus. Results Among 493 participants, 274 (55.6%) were seropositive both pre- and post-3V (+/+) while 115 (23.3%) seroconverted to positive from prior negative following the third dose (-/+). The remaining 104 (21.1%) were seronegative both before and after 3V (-/-). No participant was seropositive pre-3V and seronegative post-3V (+/-). Results showed a statistically significant increase in the proportion of seropositivity after receiving a third COVID-19 vaccine (P<0.00001). Response to 3V was significantly associated with the 3V vaccine type (P=0.0006), previous COVID-19 infection (P=0.0453), and malignancy diagnosis (P<0.0001). Likelihood of seroconversion (-/+) after 3V was higher in the group of patients with multiple myeloma or related disorders compared to patients with lymphoid leukemias (odds ratio: 8.22, 95% CI: 2.12-31.79; P=0.0008). Conclusions A third COVID-19 vaccination is effective in producing measurable seroconversion in many patients with hematologic malignancies. Oncologists should actively encourage all their patients, especially those with multiple myeloma, to receive a 3V, given the high likelihood of seroconversion.","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"9 3","pages":"149-157"},"PeriodicalIF":1.7,"publicationDate":"2022-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302908/pdf/jpcrr-9.3.149.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40675669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virtual Behavioral Health Treatment Satisfaction and Outcomes Across Time.","authors":"Mindy R Waite, Sara Diab, James Adefisoye","doi":"10.17294/2330-0698.1918","DOIUrl":"10.17294/2330-0698.1918","url":null,"abstract":"<p><strong>Purpose: </strong>The COVID-19 pandemic continues to have major and long-lasting impacts on health care delivery and mental health. As health care shifted to telehealth, legislation was adjusted to expand telehealth allowances, creating a unique opportunity to elucidate outcomes. The aim of this study was to assess long-term patient and clinician satisfaction and outcomes with virtual behavioral health.</p><p><strong>Methods: </strong>Data were obtained over 16 months from surveys to patients and clinicians receiving/providing virtual treatment. Outcomes data also were collected from medical records of adults receiving in-person and virtual behavioral health treatment. Data were summarized using descriptive statistics. Groups were compared using various chi-squared tests for categorical variables, Likert response trends over time, and conditional independence, with Wilcoxon rank-sum or Jonckheere trend test used to assess continuous variables. P-values of ≤0.05 were considered statistically significant.</p><p><strong>Results: </strong>Patients gave high ratings to virtual treatment and indicated a preference for virtual formats. Both patient and clinician preference for virtual visits increased significantly with time, and many clinicians perceived virtual services to be equally effective to in-person. Virtual programs had higher completion rates, attendance rates, and number of treatment visits, suggesting that virtual behavioral health had equivalent or better outcomes to in-person treatment and that attitudes toward telehealth changed over time.</p><p><strong>Conclusions: </strong>If trends found in this study continue, telehealth may emerge as a preferred option long term This is important considering the increase in mental health needs associated with the COVID-19 pandemic and the eventuality that in-person restrictions ease as the pandemic subsides.</p>","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"9 3","pages":"158-165"},"PeriodicalIF":1.6,"publicationDate":"2022-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302910/pdf/jpcrr-9.3.158.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40675672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin D Level Testing in an Urban Midwest Clinic: To Test or Not to Test?","authors":"D. Mundt, Marianne Klumph, K. Heslin, Wajih Askar","doi":"10.17294/2330-0698.1854","DOIUrl":"https://doi.org/10.17294/2330-0698.1854","url":null,"abstract":"Vitamin D deficiency (VDD) is significantly higher among urban populations in the U.S. Midwest, with African Americans being disproportionately affected. There is ongoing debate surrounding who and how often individuals should be screened for VDD. This study aimed to understand the prevalence of VDD, associated risk factors, and discrepancies in testing at an urban-based internal medicine residency clinic. Data were retrospectively collected on all adult patients seen by the clinic during 2018 and descriptive statistical analysis performed. Among 3976 total patients (mean age: 53 years), 18% (n=698) had vitamin D levels analyzed, with deficiency found in 71% of those tested. Mean age of the tested cohort was 59 years, and women (68%) and African Americans (72%) were found more likely to be tested. Women and patients with certain medical conditions were more likely to be tested (P<0.02 for all) but were not more likely to have VDD. Individuals with a diagnosis of chronic kidney disease were less likely to have VDD (P=0.002). Vitamin D levels typically showed improvement after retesting. A low testing rate could contribute to missed diagnoses. Overall, this study revealed that differences in rate of testing do not necessarily correlate to patients' demographical risk of VDD. Clinicians may benefit from a standardized vitamin D testing protocol.","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"9 2 1","pages":"122-127"},"PeriodicalIF":1.7,"publicationDate":"2022-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47837827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Characteristics, Risk Factors, and Outcomes Among a Large Midwestern U.S. Cohort of Patients Hospitalized With COVID-19 Prior to Vaccine Availability.","authors":"V. Zlochiver, A. P. Perez Moreno, Michael Joseph Peterson, Khalil Odeh, Ashley Mainville, Katherine Busniewski, Jon Wrobel, Mohamed Hommeida, Blair L. Tilkens, P. Sharma, Hluechy X. Vang, Sara Walczak, Fekadesilassie Moges, Kritika Garg, A. J. Tajik, S. Allaqaband, T. Bajwa, M. Jan","doi":"10.17294/2330-0698.1889","DOIUrl":"https://doi.org/10.17294/2330-0698.1889","url":null,"abstract":"Purpose\u0000The COVID-19 pandemic posed unprecedented demands on health care. This study aimed to characterize COVID-19 inpatients and examine trends and risk factors associated with hospitalization duration, intensive care unit (ICU) admission, and in-hospital mortality.\u0000\u0000\u0000Methods\u0000This retrospective study analyzed patients with SARS-CoV-2 infection hospitalized at an integrated health system between February 2, 2020, and December 12, 2020. Patient characteristics and clinical outcomes were obtained from medical records. Backward stepwise logistic regression analyses were used to identify independent risk factors of ICU admission and in-hospital mortality. Cox proportional hazards models were used to evaluate relationships between ICU admission and in-hospital mortality.\u0000\u0000\u0000Results\u0000Overall, 9647 patients were analyzed. Mean age was 64.6 ± 18 years. A linear decrease was observed for hospitalization duration (0.13 days/week, R2=0.71; P<0.0001), ICU admissions (0.35%/week, R2=0.44; P<0.001), and hospital mortality (0.16%/week, R2=0.31; P<0.01). Bacterial co-infections, male sex, history of chronic lung and heart disease, diabetes, and Hispanic ethnicity were identified as independent predictors of ICU admission (P<0.001). ICU admission and age of ≥65 years were the strongest independent risk factors associated with in-hospital mortality (P<0.001). The in-hospital mortality rate was 8.3% (27.4% in ICU patients, 2.6% in non-ICU patients; P<0.001).\u0000\u0000\u0000Conclusions\u0000Results indicate that, over the pandemic's first 10 months, COVID-19 carried a heavy burden of morbidity and mortality in older patients (>65 years), males, Hispanics, and those with bacterial co-infections and chronic comorbidities. Although disease severity has steadily declined following administration of COVID-19 vaccines along with improved understanding of effective COVID-19 interventions, these study findings reflect a \"natural history\" for this novel infectious disease in the U.S. Midwest.","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"9 2 1","pages":"132-141"},"PeriodicalIF":1.7,"publicationDate":"2022-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41444672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Natural Waterways and Legionella pneumophila Infection in Eastern Wisconsin: A Case-Control Study.","authors":"H. William, K. Heslin, J. Kram, Caroline P Toberna, D. Baumgardner","doi":"10.17294/2330-0698.1872","DOIUrl":"https://doi.org/10.17294/2330-0698.1872","url":null,"abstract":"Preliminary research has suggested possible associations between natural waterways and Legionella infection, and we previously explored these associations in eastern Wisconsin using positive L. pneumophila serogroup 1 urine antigen tests (LUAT) as diagnostic. This case-control study was a secondary analysis of home address data from patients who underwent LUAT at a single eastern Wisconsin health system from 2013 to 2017. Only zip codes within the health system's catchment area that registered ≥3 positive cases and ≥50 completed tests, as well as geographically adjacent zip codes with ≥2 positive cases and ≥50 tests, were included. A 1:3 ratio of cases to randomly selected controls was used. Home addresses were geocoded and mapped using ArcGIS software (Esri); nearest waterway and distance to home was identified. Distance to nearest waterway according to ArcGIS was verified/corrected using Google Maps incognito. Distances were analyzed using chi-squared and 2-sample t-tests. Overall, mean distance to nearest waterway did not differ between cases (2958 ± 2049 ft) and controls (2856 ± 2018 ft; P=0.701). However, in a subset of nonurban zip codes, cases were closer to nearest waterway than controls (1165 ± 905 ft vs 2113 ± 1710 ft; P=0.019). No association was found between cases and type of waterway. Further research is needed to investigate associations and differences between natural and built environmental water sources in relation to legionellosis.","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"9 2 1","pages":"128-131"},"PeriodicalIF":1.7,"publicationDate":"2022-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44007291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations Between Residential Greenspace, Socioeconomic Status, and Stroke: A Matched Case-Control Study.","authors":"Heloise Cheruvalath, J. Homa, Maharaj Singh, Paul Vilar, A. Kassam, R. Rovin","doi":"10.17294/2330-0698.1886","DOIUrl":"https://doi.org/10.17294/2330-0698.1886","url":null,"abstract":"Purpose\u0000Studies have shown increased residential greenspace is associated with improved outcome following stroke. This study sought to determine if residential greenspace is an independent stroke risk factor.\u0000\u0000\u0000Methods\u0000A retrospective 1:4 matched case-control study involving 1174 stroke and 4696 control patients over a 3-year period from Milwaukee County, Wisconsin, was conducted. Greenspace was determined using normalized difference vegetation index (NDVI) for a 250-meter radius surrounding a subject's residence. The area deprivation index (ADI) for the census block tract of a subject's residence was obtained from the Neighborhood Atlas® (University of Wisconsin School of Medicine and Public Health). Relationship between greenspace, ADI, and stroke was determined using conditional logistic regression. Relationships among NDVI, state and national ADI, and proximity to public parks were determined using Spearman's rank-order correlation.\u0000\u0000\u0000Results\u0000NDVI and stroke risk were inversely correlated (odds ratio [OR]: 0.33, 95% CI: 0.111-0.975; P=0.045), with 19% lowered odds of stroke for patients living in the highest greenspace quartile compared to the lowest quartile (OR: 0.81, 95% CI: 0.672-0.984; P=0.045). Patients living in the most deprived ADI quartile had 28% greater stroke risk than those living in the least deprived ADI quartile (OR: 1.28, 95% CI: 1.02-1.6; P=0.029). Non-Hispanic Black patients lived in residential areas with lower greenspace (P<0.001) and neighborhoods of greater state and national ADI (P<0.001 for both) than non-Hispanic White patients.\u0000\u0000\u0000Conclusions\u0000In Milwaukee County, living with greater surrounding greenspace or areas of lower deprivation is associated with lower odds of stroke. NDVI represents an independent risk factor for stroke, not simply a proxy for socioeconomic status.","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"9 2 1","pages":"89-97"},"PeriodicalIF":1.7,"publicationDate":"2022-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47980145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sitting.","authors":"J. Brill","doi":"10.17294/2330-0698.1940","DOIUrl":"https://doi.org/10.17294/2330-0698.1940","url":null,"abstract":"During a local COVID-19 surge in late 2021, salaried health system leaders were asked to volunteer for nonclinical hospital shifts to help alleviate staffing shortages. The author, a family physician by training now working largely in a population health administrative role, signed up to serve as a patient sitter. This story explores how taking on the vantage point of a sitter enabled the author to reflect on the premise of watching and being watched, the diverse team that keeps an emergency department running, and how human connection may even contribute to normalizing heart rate. (Note: Pseudonyms are used in place of actual names and some details withheld to protect the privacy of the individuals involved.).","PeriodicalId":16724,"journal":{"name":"Journal of Patient-Centered Research and Reviews","volume":"9 2 1","pages":"142-143"},"PeriodicalIF":1.7,"publicationDate":"2022-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43854482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}