{"title":"Thank You to Reviewers • Mot de remerciement aux évaluateurs","authors":"","doi":"10.1016/j.jogc.2025.102827","DOIUrl":"10.1016/j.jogc.2025.102827","url":null,"abstract":"","PeriodicalId":16688,"journal":{"name":"Journal of obstetrics and gynaecology Canada","volume":"47 4","pages":"Article 102827"},"PeriodicalIF":2.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143807715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is There an Alternative “Advanced Maternal Age” Threshold for Recommendation of Invasive Prenatal Testing?","authors":"Idit Maya MD , Liat Salzer Sheelo MD , Dana Brabbing-Goldstein MD , Reut Matar PhD , Sarit Kahana PhD , Ifaat Agmon-Fishman MSc , Cochava Klein MSc , Merav Gurevitch PhD , Lina Basel-Salmon MD PhD , Lena Sagi-Dain MD","doi":"10.1016/j.jogc.2025.102821","DOIUrl":"10.1016/j.jogc.2025.102821","url":null,"abstract":"<div><div>This retrospective cohort study aimed to examine the appropriate maternal age threshold for recommendation of invasive prenatal testing. We calculated the rate of clinically significant microarray findings in pregnancies with normal fetal ultrasound per each year of maternal age, to estimate the optimal cut-off. Of the 7033 prenatal microarray analyses, 108 (1.53%) clinically significant results were noted. Receiver operating characteristics analysis failed to define a specific maternal age cut-off, in the overall cohort as well following the omission of non-invasive prenatal screening-detectable common autosomal trisomies. This implies that each woman should be offered the possibility of invasive testing, preferably publicly funded.</div></div>","PeriodicalId":16688,"journal":{"name":"Journal of obstetrics and gynaecology Canada","volume":"47 5","pages":"Article 102821"},"PeriodicalIF":2.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143757665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oocyte Cryopreservation Outcomes in Women With Hematological Malignancies Undergoing Chemotherapy—A Systematic Review and Meta-Analysis","authors":"Stéphanie Dufour MD , Sophie-Anne Gagné BSc , Aaron Jackson MD , Lesleigh Abbott MD , Clara Q. Wu MD MSc","doi":"10.1016/j.jogc.2025.102824","DOIUrl":"10.1016/j.jogc.2025.102824","url":null,"abstract":"<div><h3>Objective</h3><div>Hematological cancers are among the leading malignancies affecting women of reproductive age. Oocyte cryopreservation (OC) is routinely recommended before initiating gonadotoxic treatments. We aim to evaluate OC outcomes in women with hematological cancers undergoing chemotherapy.</div></div><div><h3>Data Sources</h3><div>A comprehensive literature search was conducted in Medline, Embase, and Cochrane Library until January 2024.</div></div><div><h3>Study Selection</h3><div>Studies examining fertility outcomes of women undergoing OC before chemotherapy for hematological cancers were included. Comparison groups included healthy controls or patients with other cancers. The primary outcome was the number of mature oocytes frozen per stimulation cycle; secondary outcomes included total cumulus-oocyte complexes, stimulation duration, total gonadotropin dose and fertility outcomes following the utilization of cryopreserved oocytes.</div></div><div><h3>Data Extraction and Synthesis</h3><div>A total of 14 cohort studies, 2 case-control studies, and 6 case reports involving 858 hematological cancer patients undergoing OC and 2676 comparators were included. The mean mature oocyte yield ranged from 7 to 19 in the hematological cancer group, and 6 to 14 in the comparator groups (mean difference [MD] 0.11; 95% CI –0.10 to 0.33). A comparable number of total cumulus-oocyte complexes (MD 0.09; 95% CI –0.07 to 0.25) and total dose of gonadotropins were found (MD 0.33; 95% CI –0.32 to 0.98). The analysis found a marginally longer duration of stimulation in the hematological cancer group (MD 0.21; 95% CI 0.11–0.31). Also, the hematological cancer group was found to be statistically younger, (MD –1.32; 95% CI –1.85 to –0.79), the difference is not clinically meaningful. Results for subgroup analyses concurred with the main analysis. Fertility and utilization of cryopreserved oocyte data were lacking.</div></div><div><h3>Conclusion</h3><div>These findings suggest that women with hematological cancers undergoing OC may expect similar oocyte yield compared to women with other cancers or healthy controls. Oocyte quality and pregnancy outcomes following the utilization of cryopreserved oocytes in hematological cancer patients remain unclear and should be the subject of further study.</div></div>","PeriodicalId":16688,"journal":{"name":"Journal of obstetrics and gynaecology Canada","volume":"47 6","pages":"Article 102824"},"PeriodicalIF":2.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Romy Barbera , Marc Beltempo MD, MSc , Rohan D’Souza MD, PhD , Sarah D. McDonald MD, MSc, BA , Stefania Ronzoni MD, PhD , Joseph Ting MBBS, MPH , Isabelle Boucoiran MD, MSc
{"title":"Canadian Survey on the Diagnosis and Clinical Management of Preterm Premature Rupture of Membranes in Tertiary Centres","authors":"Romy Barbera , Marc Beltempo MD, MSc , Rohan D’Souza MD, PhD , Sarah D. McDonald MD, MSc, BA , Stefania Ronzoni MD, PhD , Joseph Ting MBBS, MPH , Isabelle Boucoiran MD, MSc","doi":"10.1016/j.jogc.2025.102822","DOIUrl":"10.1016/j.jogc.2025.102822","url":null,"abstract":"<div><div>This study examines diagnostic and management practices for preterm premature rupture of membranes before 34 weeks in Canada. Between August and November 2023, obstetricians from the Canadian Preterm Birth Network (28 sites) completed an online survey. The response rate was 79% (n = 22). Preferred diagnostic tests include the fern test (91%) and nitrazine paper test (77%). Home management is offered in 64% of sites. The most used antibiotherapy (55%) combines macrolide and ampicillin followed by amoxicillin. Group B <em>Streptococcus</em> status rarely influences delivery timing (86%). Four sites have no management protocol. Preterm premature rupture of membranes management varies across Canada, highlighting the need for standardization.</div></div>","PeriodicalId":16688,"journal":{"name":"Journal of obstetrics and gynaecology Canada","volume":"47 6","pages":"Article 102822"},"PeriodicalIF":2.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Atoosa Golfar BSc, MD , Joanne K. Olson PhD, RN, FAAN , Ewurakua Obeng-Nkansah BScN, RN , Hefseeba Biju BScN, RN , David M. Olson PhD, DSc
{"title":"Screening and Interventions for Intimate Partner Violence in Pregnancy: The Perspective of Survivors","authors":"Atoosa Golfar BSc, MD , Joanne K. Olson PhD, RN, FAAN , Ewurakua Obeng-Nkansah BScN, RN , Hefseeba Biju BScN, RN , David M. Olson PhD, DSc","doi":"10.1016/j.jogc.2025.102826","DOIUrl":"10.1016/j.jogc.2025.102826","url":null,"abstract":"<div><h3>Objectives</h3><div>Intimate partner violence (IPV) poses serious risks to women's health, especially during pregnancy. Despite pregnancy being a key opportunity for IPV screening, various barriers often hinder health care provider efforts to screen for IPV. This study seeks to understand from IPV survivors how health care providers can better screen for and address IPV during pregnancy.</div></div><div><h3>Methods</h3><div>Women who had experienced IPV during pregnancy were recruited via Facebook ads. A website provided study details and a consent form. After consenting, participants completed a survey covering 4 main themes: personal demographics, IPV screening in pregnancy, barriers to disclosure, and interventions offered. Written comments were invited in addition to survey completion.</div></div><div><h3>Results</h3><div>This pilot study involved 23 participants who experienced IPV during pregnancy. Overall, 17 reported childhood abuse and 19 had experienced abuse outside of pregnancy. Although all participants supported IPV screening by health care providers during prenatal care, only 8 were screened. There was a preference for written tools over verbal assessments to enhance comfort and privacy. Barriers to disclosure included fear of partner retaliation, discomfort discussing IPV, concerns about confidentiality, and potential involvement of child protection services. Interventions offered were limited, with mental health support and social services identified as critical resources.</div></div><div><h3>Conclusions</h3><div>Findings support the need for improved screening practices and comprehensive support systems to address the complex needs of pregnant individuals experiencing IPV, particularly given its prevalence and ties to childhood trauma. Enhancing standardized guidelines, health care provider training, and disclosure support are essential for promoting healthier outcomes for mothers and their children.</div></div>","PeriodicalId":16688,"journal":{"name":"Journal of obstetrics and gynaecology Canada","volume":"47 6","pages":"Article 102826"},"PeriodicalIF":2.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring the Experiences of Ontario Postsecondary Students With the Emergency Contraception Pill","authors":"Kathleen Szajbely BSc, Elena Neiterman PhD","doi":"10.1016/j.jogc.2025.102825","DOIUrl":"10.1016/j.jogc.2025.102825","url":null,"abstract":"<div><h3>Objectives</h3><div>This research aimed to explore how female postsecondary students in Ontario describe their experiences of obtaining the emergency contraceptive pill (ECP), and what methods and strategies they used to obtain ECP.</div></div><div><h3>Methods</h3><div>Qualitative semi-structured interviews with 11 female postsecondary students in Ontario who have taken ECP occurred in January 2024. Participants were 18–23 years old and included undergraduate, graduate, and medical students. Anonymized transcripts were analyzed using interpretative phenomenology.</div></div><div><h3>Results</h3><div>The decision of how to obtain emergency contraception pills was impacted by a lack of accurate information. Participants used various methods to access emergency contraception pills, including drawing attention away from themselves, obtaining emergency contraception pills in a group, or having intimate partners purchase emergency contraception pills. Stigma and perception of judgement influenced participants’ experiences obtaining emergency contraception pills.</div></div><div><h3>Conclusions</h3><div>The experience of obtaining emergency contraception pills was negative but necessary to avoid pregnancy for participants. Women in this qualitative study used alternative strategies to obtain emergency contraception pills due to the experience of a lack of body autonomy, misinformation, and access.</div></div>","PeriodicalId":16688,"journal":{"name":"Journal of obstetrics and gynaecology Canada","volume":"47 6","pages":"Article 102825"},"PeriodicalIF":2.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Savitha Balachandran BSc , Bahi Fayek MSc, MD , Sabina Dobrer MA , Sarka Lisonkova MD, PhD , Amr O. Abdelkareem MD , Paul J. Yong MD, PhD , K.S. Joseph MD, PhD , Mohamed A. Bedaiwy MD, PhD
{"title":"COVID-19 and Recurrent Pregnancy Loss Management: Trends in Clinical Care From a Tertiary Centre","authors":"Savitha Balachandran BSc , Bahi Fayek MSc, MD , Sabina Dobrer MA , Sarka Lisonkova MD, PhD , Amr O. Abdelkareem MD , Paul J. Yong MD, PhD , K.S. Joseph MD, PhD , Mohamed A. Bedaiwy MD, PhD","doi":"10.1016/j.jogc.2025.102817","DOIUrl":"10.1016/j.jogc.2025.102817","url":null,"abstract":"<div><h3>Objectives</h3><div>To investigate the impact of the COVID-19 pandemic on the care received by patients with recurrent pregnancy loss (RPL) in British Columbia, Canada. To explore the differential impact of socioeconomic status on health care utilization outcomes during the COVID-19 pandemic for patients with RPL.</div></div><div><h3>Methods</h3><div>This is a retrospective cohort study of patients from an RPL clinic located within a tertiary referral centre. Patients were divided into 2 groups based on the date of their initial visit to the clinic: (1) pre-pandemic group (March 1, 2018–February 28, 2020) and (2) pandemic group (March 1, 2020–February 28, 2022). Data were sourced from the RPL Clinic Database and Population Data BC. Outcomes assessed included visit trends, immediate pandemic impact, and socioeconomic effects.</div></div><div><h3>Results</h3><div>Demographic and clinical characteristics were not significantly different between study groups, except for increased referral rates to fertility clinics by the RPL clinic during the COVID-19 pandemic (4.90% vs. 9.50%). The mean number of visits per patient was comparable between pre-pandemic (3.50 ± 2.00) and during the pandemic (3.40 ± 3.40). However, monthly initial visits were lower during the pandemic (12.50 ± 3.10) compared with pre-pandemic (14.40 ± 4.83). Telehealth was rare in the pre-pandemic period and increased dramatically during the pandemic, with virtual visits reaching up to 64% of total and 94% of initial visits. The pandemic’s onset caused immediate drops in total (38.80%) and initial visits (51.70%). Health care utilization was higher among those with less material deprivation, whereas contrasting effects were observed in those with less social deprivation.</div></div><div><h3>Conclusions</h3><div>The COVID-19 pandemic impacted the care received by patients with RPL within a tertiary care centre. There was a shift in how services were provided to patients, uniquely impacting specific populations within the community.</div></div>","PeriodicalId":16688,"journal":{"name":"Journal of obstetrics and gynaecology Canada","volume":"47 5","pages":"Article 102817"},"PeriodicalIF":2.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meiqi Li MD , Chenyu Xiao MD , Qianru Li MD , Leilei Gao MD, PhD
{"title":"An Interesting Case: A Levonorgestrel-Releasing Intrauterine System (LNG-IUS) Embedded in a Fiber Mass","authors":"Meiqi Li MD , Chenyu Xiao MD , Qianru Li MD , Leilei Gao MD, PhD","doi":"10.1016/j.jogc.2025.102813","DOIUrl":"10.1016/j.jogc.2025.102813","url":null,"abstract":"","PeriodicalId":16688,"journal":{"name":"Journal of obstetrics and gynaecology Canada","volume":"47 5","pages":"Article 102813"},"PeriodicalIF":2.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}