Journal of Orthopaedic Case Reports最新文献

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Atraumatic Bilateral Patellar Tendon Rupture: A Case Report.
Journal of Orthopaedic Case Reports Pub Date : 2025-03-01 DOI: 10.13107/jocr.2025.v15.i03.5354
Venkata Vinay Atluri, Vishwanath Mahadevuni, Akhilesh Reddy Ganta, V R Sujit Kumar
{"title":"Atraumatic Bilateral Patellar Tendon Rupture: A Case Report.","authors":"Venkata Vinay Atluri, Vishwanath Mahadevuni, Akhilesh Reddy Ganta, V R Sujit Kumar","doi":"10.13107/jocr.2025.v15.i03.5354","DOIUrl":"https://doi.org/10.13107/jocr.2025.v15.i03.5354","url":null,"abstract":"<p><strong>Introduction: </strong>Bilateral patellar tendon rupture is an uncommon reason for extensor mechanism dysfunction. Various predisposing factors, including systemic diseases and the use of steroids or antibiotics, can elevate the risk. The patient typically presents with an inability to extend the knee, generalized pain and swelling, and a high-riding patella observed on lateral radiographs.</p><p><strong>Case report: </strong>We report a case involving a 44-year-old man with no underlying risk factors or systemic disease who sustained a bilateral patellar tendon rupture following minor trauma. The patient was treated with bilateral primary transosseous end-to-end tendon repair, followed by a brief period of immobilization and an intensive rehabilitation program. Six months post-surgery, he could walk unassisted without pain, regain full range of motion in both knees, and carry out daily activities without limitations.</p><p><strong>Conclusion: </strong>Timely diagnosis and immediate surgical intervention are crucial to preventing complications related to extensor mechanism failure and ensuring favorable functional outcomes.</p>","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 3","pages":"115-120"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Controversial Late Effect of Shoulder Radiation Therapy in a Small Case Series.
Journal of Orthopaedic Case Reports Pub Date : 2025-03-01 DOI: 10.13107/jocr.2025.v15.i03.5344
Tito Brambullo, Francesca Zanon, Gloria Fanton, Giulia Trovarelli, Franco Bassetto, Vincenzo Vindigni
{"title":"The Controversial Late Effect of Shoulder Radiation Therapy in a Small Case Series.","authors":"Tito Brambullo, Francesca Zanon, Gloria Fanton, Giulia Trovarelli, Franco Bassetto, Vincenzo Vindigni","doi":"10.13107/jocr.2025.v15.i03.5344","DOIUrl":"https://doi.org/10.13107/jocr.2025.v15.i03.5344","url":null,"abstract":"<p><strong>Introduction: </strong>Radiodermatitis is a common complication experienced by patients undergoing radiation therapy. Its severity can vary from mild erythema to more serious conditions, including desquamation, ulceration, and, in extreme cases, necrosis. In addition, it is widely acknowledged that radiotherapy (RT) itself carries oncogenic risks, potentially causing cellular mutations that may lead to the development of neoplasms, sometimes years after treatment. Diagnostic and staging tools such as magnetic resonance imaging, computed tomography, and positron emission tomography scans are crucial in these cases, with biopsy serving as the definitive method for histological confirmation. However, large excisions often required in these situations necessitate complex reconstructive procedures and are associated with a high risk of local complications, including wound dehiscence and infection.</p><p><strong>Case report: </strong>We present three cases of radiodermatitis that developed following radiation therapy to the shoulder. These cases highlight the need to consider radiodermatitis as a differential diagnosis for skin changes occurring after RT, especially in patients with a history of cancer.</p><p><strong>Conclusion: </strong>The misdiagnosis or delayed diagnosis of radiodermatitis can substantially increase patient morbidity. Greater awareness of this potential complication underscores the importance of closely monitoring for skin-related issues in patients receiving RT.</p>","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 3","pages":"86-92"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907151/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Joint Reconstruction using Tricortical Iliac Crest Bone Graft Block for Intra-Articular Extension of Aneurysmal Bone Cyst of Distal Tibia in a Skeletally Mature Patient - A Case Report and Review of Literature.
Journal of Orthopaedic Case Reports Pub Date : 2025-03-01 DOI: 10.13107/jocr.2025.v15.i03.5326
Shaswat Mishra, Manish Jain, Vishal Lalchandani, Mrinal Kambli, Satyajeet Dash
{"title":"Joint Reconstruction using Tricortical Iliac Crest Bone Graft Block for Intra-Articular Extension of Aneurysmal Bone Cyst of Distal Tibia in a Skeletally Mature Patient - A Case Report and Review of Literature.","authors":"Shaswat Mishra, Manish Jain, Vishal Lalchandani, Mrinal Kambli, Satyajeet Dash","doi":"10.13107/jocr.2025.v15.i03.5326","DOIUrl":"https://doi.org/10.13107/jocr.2025.v15.i03.5326","url":null,"abstract":"<p><strong>Introduction: </strong>Aneurysmal bone cysts (ABC) are known to be largely limited to the metaphysis. Epiphyseal extension of the lesion that too in a skeletally mature patient, has rarely been reported. Further, literature regarding the management of these lesions, where sclerotherapy failed, is scarce. We describe a case of distal tibia ABC with intra-articular extension, managed with curettage and iliac crest allograft auto-graft block reconstruction of the joint with excellent functional outcome.</p><p><strong>Case report: </strong>The authors report a case of a 20-year-old lady presenting with swelling and pain in her ankle joint. X-rays and magnetic resonance imaging showed an ABC in the distal tibia with extension to the joint. Biopsy confirmed the diagnosis which was followed by sclerotherapy, but the lesion recurred in a year. Surgery in the form of excision, curettage, and joint reconstruction using tricortical iliac crest bone autograft block was done which was fixed with plate osteosynthesis.</p><p><strong>Result and discussion: </strong>The patient under follow-up at 3 years shows excellent clinical outcome, no evidence of recurrence, able to perform out carry out her personal and professional activities with no restrictions. Addressing such a case is a difficult task, and in a financially constrained patient scenario such as ours, brings its own set of challenges. Such cases of joint involvement in ABCs are very rare, and literature on the management of such lesions is even more scarce. Therefore, they need reporting to help formulating better treatment protocols in such difficult scenarios.</p><p><strong>Conclusion: </strong>The reconstructive of the ankle joint with tricortical iliac crest bone grafting in ABC of distal tibia with joint involvement can provide excellent clinical and radiological outcomes.</p>","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 3","pages":"37-42"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907155/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Mentorship in Orthopedic Professional Development: From Training to Mastery.
Journal of Orthopaedic Case Reports Pub Date : 2025-03-01 DOI: 10.13107/jocr.2025.v15.i03.5414
Janki Sharan Bhadani, John Mukhopadhaya
{"title":"The Role of Mentorship in Orthopedic Professional Development: From Training to Mastery.","authors":"Janki Sharan Bhadani, John Mukhopadhaya","doi":"10.13107/jocr.2025.v15.i03.5414","DOIUrl":"https://doi.org/10.13107/jocr.2025.v15.i03.5414","url":null,"abstract":"<p><strong>Introduction: </strong>Mentorship is essential to the professional and personal development of orthopedic surgeons. It promotes continuous learning, supports career development, and helps develop future leaders in the field. Our study explains key aspects of effective mentorship, differentiates mentorship from coaching, and highlights strategies to enhance mentor-mentee relationships.</p><p><strong>Materials and methods: </strong>A literature review was conducted to identify best practices in orthopedic mentorship using established models, expert opinions, and real-world training experiences.</p><p><strong>Results: </strong>Strong mentorship positively impacts skill development, career progression, and overall job satisfaction. Key elements include structured guidance, open communication, and mutual commitment. Differences between mentorship and coaching were elucidated, emphasizing their distinct roles in professional development.</p><p><strong>Discussion: </strong>Effective mentorship programs require formal structures, clear expectations, and institutional support. Successful mentor-mentee relationships thrive on trust, regular feedback, and goal alignment. Practical strategies to strengthen mentorship in orthopedic training include mentorship training for faculty, structured pairing programs, and promoting a supportive learning environment.</p><p><strong>Conclusion: </strong>Mentorship is critical in orthopedic education and career development. Establishing strong mentorship programs can enhance learning, improve professional satisfaction, and develop future leaders in the specialty. Institutions should prioritize structured mentorship frameworks to ensure long-term success.</p>","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 3","pages":"289-300"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907144/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of Platelet-Rich Plasma in Treating Rotator Cuff Tendinopathy: A Systematic Review and Meta-Analysis.
Journal of Orthopaedic Case Reports Pub Date : 2025-03-01 DOI: 10.13107/jocr.2025.v15.i03.5408
Mainak Roy, Mulagondla Harshavardhan Reddy, Deepanjan Das, Priyanshu, Denish Chandrakar, A Muhil Elavarasu
{"title":"Effectiveness of Platelet-Rich Plasma in Treating Rotator Cuff Tendinopathy: A Systematic Review and Meta-Analysis.","authors":"Mainak Roy, Mulagondla Harshavardhan Reddy, Deepanjan Das, Priyanshu, Denish Chandrakar, A Muhil Elavarasu","doi":"10.13107/jocr.2025.v15.i03.5408","DOIUrl":"https://doi.org/10.13107/jocr.2025.v15.i03.5408","url":null,"abstract":"<p><strong>Introduction: </strong>Rotator cuff tendinopathy often causes significant shoulder pain and limits function. Traditional treatments, such as physical therapy and corticosteroid injections, provide inconsistent relief. Platelet-rich plasma (PRP) has emerged as a promising regenerative therapy for pain relief and tendon healing. This systematic review and meta-analysis evaluated PRP's effectiveness compared to placebo or other treatments.</p><p><strong>Materials and methods: </strong>A thorough search of PubMed, Embase, and Cochrane Library focused on randomized controlled trials (RCTs) using PRP as a primary intervention for rotator cuff tendinopathy. Eligible studies included pain reduction, functional improvement, and retear rates as outcomes. Data were extracted and analyzed using standardized methods.</p><p><strong>Results: </strong>Thirty RCTs with around 2,500 participants were included in the study. PRP significantly reduced pain and improved function in the short term compared to placebo and corticosteroids. However, long-term benefits (beyond 12 months) were limited, with retear rates and function similar to control groups.</p><p><strong>Conclusion: </strong>PRP provides significant short-term pain relief and functional improvement in rotator cuff tendinopathy but does not demonstrate superior long-term benefits over placebo or corticosteroids.</p>","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 3","pages":"265-274"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single-stage reconstruction without grafting for neglected flexor pollicis longus tendon laceration in a child - A case report.
Journal of Orthopaedic Case Reports Pub Date : 2025-03-01 DOI: 10.13107/jocr.2025.v15.i03.5372
Christos Kotsias, Vasileios Panagiotopoulos, Christos Koukos, Dimitrios Vardakas, Samundeeswari Saseendar, Dimitrios Giotis
{"title":"Single-stage reconstruction without grafting for neglected flexor pollicis longus tendon laceration in a child - A case report.","authors":"Christos Kotsias, Vasileios Panagiotopoulos, Christos Koukos, Dimitrios Vardakas, Samundeeswari Saseendar, Dimitrios Giotis","doi":"10.13107/jocr.2025.v15.i03.5372","DOIUrl":"https://doi.org/10.13107/jocr.2025.v15.i03.5372","url":null,"abstract":"<p><strong>Introduction: </strong>Lacerations of the flexor pollicis longus (FPL) tendon are rare in children and should be treated promptly. This study aims to present a rare case of a neglected FPL tendon laceration in a child, successfully managed with single-stage reconstruction without the use of grafts.</p><p><strong>Case report: </strong>A 12-year-old patient was admitted to our hospital with an inability to flex the interphalangeal joint of the right thumb following an injury sustained 2 months earlier. Clinical examination revealed a neglected FPL tendon laceration in zone II. Intraoperatively, it was observed that the distal stump of the tendon measured approximately 1 cm, while the proximal stump was attached to the A1 pulley. In addition, the oblique pulley was narrowed, obstructing the passage of the tendon. To address this, a Z-plasty of the oblique pulley was performed. Following tendon debridement, a 2-cm-long tendon deficit was identified. A carpal tunnel release was conducted to facilitate further tendon mobilization. The distal stump was sutured, and a Z-plasty lengthening of the tendon by 1.5 cm was performed after assessing the \"tenodesis effect.\" An extension block cast was applied after skin closure. Three weeks later, the patient was encouraged to perform active flexion-extension movements to the neutral position. By 6 weeks postoperatively, the patient was advised to perform full active range-of-motion exercises and physiotherapy. Four months after surgery, the patient had fully resumed pre-injury activities exhibiting full active flexion and a 10° extension deficit at the IP joint of the thumb.</p><p><strong>Conclusion: </strong>In cases of neglected pediatric flexor tendon lacerations, single-stage tendon reconstruction without grafting can be a viable option to avoid complex surgical procedures and potentially unpredictable outcomes.</p>","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 3","pages":"160-164"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tardy Posterior Interosseous Nerve Palsy as a Complication of Unreduced Monteggia Fracture: A Case Report and Literature Review.
Journal of Orthopaedic Case Reports Pub Date : 2025-03-01 DOI: 10.13107/jocr.2025.v15.i03.5350
Fernando Macedo, Miguel Rocha, João Lucas, Luís Filipe Rodrigues, Pedro Varanda, Elisabete Ribeiro
{"title":"Tardy Posterior Interosseous Nerve Palsy as a Complication of Unreduced Monteggia Fracture: A Case Report and Literature Review.","authors":"Fernando Macedo, Miguel Rocha, João Lucas, Luís Filipe Rodrigues, Pedro Varanda, Elisabete Ribeiro","doi":"10.13107/jocr.2025.v15.i03.5350","DOIUrl":"https://doi.org/10.13107/jocr.2025.v15.i03.5350","url":null,"abstract":"<p><strong>Introduction: </strong>While acute posterior interosseous nerve (PIN) palsy is a recognized complication of Monteggia fractures, delayed or tardy PIN palsy due to persistent radial head dislocation is exceedingly uncommon.</p><p><strong>Case report: </strong>We describe a case of tardy PIN palsy 29 years after an unreduced Monteggia fracture, Bado type I.</p><p><strong>Conclusion: </strong>While rare, delayed PIN palsy can occur in patients with old, unreduced Monteggia fractures. This underscores the need for a thorough medical history to detect potential causes, as long-standing injuries may eventually present symptoms. Treatment should target the underlying compression from the fracture dislocation while preserving the patient's adapted function.</p>","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 3","pages":"107-110"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907162/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Myxoma of the Dorsal Aspect of the Hand - A Case Report of a Rare Condition.
Journal of Orthopaedic Case Reports Pub Date : 2025-03-01 DOI: 10.13107/jocr.2025.v15.i03.5314
Rui Sousa, Raquel Cunha, Marta Santos Silva, Mário Gonçalves, Vera Resende, Artur Neto
{"title":"Myxoma of the Dorsal Aspect of the Hand - A Case Report of a Rare Condition.","authors":"Rui Sousa, Raquel Cunha, Marta Santos Silva, Mário Gonçalves, Vera Resende, Artur Neto","doi":"10.13107/jocr.2025.v15.i03.5314","DOIUrl":"https://doi.org/10.13107/jocr.2025.v15.i03.5314","url":null,"abstract":"<p><strong>Introduction: </strong>Myxoma is a rare benign tumor of primitive connective tissue, most commonly found in the heart. It can also occur in other soft tissues, such as the skin, muscles, jawbones, and near joints. Myxomas of the upper limb, particularly in the hand, are extremely rare. This case adds to the limited literature on hand myxomas, providing insights into its clinical presentation, diagnosis, and management. Apart from this case, only two more cases of myxoma with similar topography have been described.</p><p><strong>Case report: </strong>A 34-year-old Caucasian female with no prior significant medical history presented with a non-painful, gradually enlarging mass on the dorsum of her right hand, which had been growing for a year and a half. The lesion was oval and mobile, without involvement of the extensor tendons. Imaging revealed a well-defined nodular lesion in the subcutaneous fat layer of the dorsomedial hand, suggestive of a myxoid-type lesion. A surgical excision was performed and a histopathological examination confirmed the diagnosis of myxoma, describing a 3 cm nodular fragment of compact, soft, mucinous tissues. At the 2-month follow-up, the patient had a fully healed wound with complete finger and wrist mobility, preserved muscular strength, and no pain. At the 1-year follow-up, no recurrence of the lesion was observed.</p><p><strong>Conclusion: </strong>This case emphasizes the need to consider myxoma in the differential diagnosis of dorsal hand swellings. Early diagnosis and complete surgical excision are essential to prevent recurrence and potential complications. The successful management and follow-up in this patient illustrate the potential for favorable outcomes with appropriate treatment. This case report provides valuable information to the literature, enhancing our understanding of the clinical presentation and management of rare myxomas in the hand and highlighting the importance of awareness and thorough evaluation in managing unusual soft-tissue tumors.</p>","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 3","pages":"8-11"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907123/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rehabilitation In Arthroscopic Anterior Cruciate Ligament Reconstruction.
Journal of Orthopaedic Case Reports Pub Date : 2025-03-01 DOI: 10.13107/jocr.2025.v15.i03.5312
Sagar Deshpande, Prerna Ghodke, Sachin Kale, Ashok Shyam
{"title":"Rehabilitation In Arthroscopic Anterior Cruciate Ligament Reconstruction.","authors":"Sagar Deshpande, Prerna Ghodke, Sachin Kale, Ashok Shyam","doi":"10.13107/jocr.2025.v15.i03.5312","DOIUrl":"https://doi.org/10.13107/jocr.2025.v15.i03.5312","url":null,"abstract":"","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 3","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary Malignant Giant Cell Tumor of Bone with Metastasis: A Case Report and Literature Review.
Journal of Orthopaedic Case Reports Pub Date : 2025-03-01 DOI: 10.13107/jocr.2025.v15.i03.5376
Hazem Aboaid, John A deVries, Russell Gollard
{"title":"Primary Malignant Giant Cell Tumor of Bone with Metastasis: A Case Report and Literature Review.","authors":"Hazem Aboaid, John A deVries, Russell Gollard","doi":"10.13107/jocr.2025.v15.i03.5376","DOIUrl":"https://doi.org/10.13107/jocr.2025.v15.i03.5376","url":null,"abstract":"<p><strong>Introduction: </strong>Malignant giant cell tumor of bone (GCTB) is a very rare tumor, especially the primary type of it. We report a case of a young female who was diagnosed with a primary malignant giant cell tumor, in addition to a literature review of the previously reported cases. This case report aims to highlight the importance of high clinical suspicion and comprehensive workup to detect malignancy in giant cell tumors. We also review and add another case to the medical literature to help better understand the behavior of this rare tumor.</p><p><strong>Case report: </strong>A 30-year-old African American female presented with left knee pain. Imaging showed a cystic bone lesion of the left proximal tibia, which was found to be consistent with a primary malignant giant cell tumor on biopsy. She started neoadjuvant chemotherapy (methotrexate + doxorubicin + cisplatin); however, she only tolerated one cycle, and then she underwent a radical resection of the left proximal tibia with endoprosthetic reconstruction. She had multiple hospitalizations later, and she was found to have significant pulmonary and spinal metastasis. Eventually, she decided to resume chemotherapy due to her worsening disease, and she completed four cycles of doxorubicin and cisplatin with a recent plan to switch to regorafenib given her refractory disease.</p><p><strong>Conclusion: </strong>Diagnosis of primary malignant GCTB can be very challenging. It is always important to seek an expert opinion given the rare nature of this tumor. Early detection is very important to establish the appropriate treatment.</p>","PeriodicalId":16647,"journal":{"name":"Journal of Orthopaedic Case Reports","volume":"15 3","pages":"169-174"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907131/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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