Journal of Pain & Palliative Care Pharmacotherapy最新文献_第9页

Outpatient Patient Controlled Analgesia (PCA) for the Palliative Care Patient. 姑息治疗病人的门诊病人控制镇痛（PCA）。

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Journal of Pain & Palliative Care Pharmacotherapy Pub Date : 2024-12-01 Epub Date: 2024-08-05 DOI: 10.1080/15360288.2024.2383415

Jacob T Painter, Kennede McLeroy-Charles, Heather Moore, Sarah Harrington, Lindsey E Dayer

{"title":"Outpatient Patient Controlled Analgesia (PCA) for the Palliative Care Patient.","authors":"Jacob T Painter, Kennede McLeroy-Charles, Heather Moore, Sarah Harrington, Lindsey E Dayer","doi":"10.1080/15360288.2024.2383415","DOIUrl":"10.1080/15360288.2024.2383415","url":null,"abstract":"This study explores the under-researched domain of patient-controlled analgesia (PCA) for cancer pain management in adult outpatients, focusing on the transition from patient-controlled analgesia pumps (PCA pump) to oral medications. While existing literature primarily addresses the use of PCA in inpatient settings, this descriptive study investigates the initiation of outpatient PCA in palliative care patients. The retrospective chart review includes data from all admissions between July 1, 2014, and December 31, 2020. Among the 49 identified patients, 41 were admitted for cancer-related pain, with an indication for PCA such as insufficient pain relief, highly fluctuating pain, or inadequate response to other routes. Of these patients, 13 were successfully transitioned from outpatient PCA to oral opioids. The study underscores the effective use of PCA as a transitional tool following a pain crisis that necessitates inpatient admission. Future research avenues could explore healthcare utilization, length of stay, and required outpatient resources, such as home visits or telehealth, for optimal PCA use in outpatient settings.","PeriodicalId":16645,"journal":{"name":"Journal of Pain & Palliative Care Pharmacotherapy","volume":" ","pages":"367-372"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141893690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methadone for Pain Management in Chemotherapy-Induced Peripheral Neuropathy: A Retrospective Review. 美沙酮用于化疗引起的周围神经病变的疼痛治疗：回顾性综述。

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Journal of Pain & Palliative Care Pharmacotherapy Pub Date : 2024-12-01 Epub Date: 2024-07-30 DOI: 10.1080/15360288.2024.2383423

Christiane Boen, Julia Ridley, Philippa Hawley

{"title":"Methadone for Pain Management in Chemotherapy-Induced Peripheral Neuropathy: A Retrospective Review.","authors":"Christiane Boen, Julia Ridley, Philippa Hawley","doi":"10.1080/15360288.2024.2383423","DOIUrl":"10.1080/15360288.2024.2383423","url":null,"abstract":"Chemotherapy-Induced Peripheral Neuropathy (CIPN) refers to damage of peripheral nerve fibers due to the use of neurotoxic chemotherapy to treat various cancers. It occurs in more than 30% of patients and only duloxetine has currently been identified to show limited efficacy in symptomatic treatment of CIPN. Opioids have traditionally been used to treat cancer pain, and there is evidence for their use in treatment of peripheral neuropathic pain from other causes. With a similar mechanism of action to duloxetine, methadone has rationale for treating neuropathic pain. This study is a retrospective chart review to evaluate the outcomes of using methadone for CIPN pain. Out of 31 patients, 65% felt that methadone was an effective treatment, 19% felt that it was ineffective, and 16% felt that it was partially or temporarily effective. These results suggest that analgesic response to methadone varies between patients, but that it has a potential role in painful CIPN. Its advantages for long-term use include low cost and lack of metabolites. Potential risks include a long half-life, drug interactions, and potential for QT prolongation at high doses. Prospective studies should be conducted to evaluate the role of methadone in CIPN pain management more comprehensively.","PeriodicalId":16645,"journal":{"name":"Journal of Pain & Palliative Care Pharmacotherapy","volume":" ","pages":"345-354"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141855804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Opioid Medication Errors in Patients Followed by Home Palliative Care Support Teams in the Community of Madrid. 马德里社区居家姑息关怀支持团队随访患者的阿片类药物用药错误。

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Journal of Pain & Palliative Care Pharmacotherapy Pub Date : 2024-12-01 Epub Date: 2024-07-05 DOI: 10.1080/15360288.2024.2369542

María Consuelo Fernández Gómez, Genoveva Díaz Sierra, María Del Carmen Peinado Cañaveras, María Antonia Berrocal Higuero, Cristina de Miguel Sánchez

{"title":"Opioid Medication Errors in Patients Followed by Home Palliative Care Support Teams in the Community of Madrid.","authors":"María Consuelo Fernández Gómez, Genoveva Díaz Sierra, María Del Carmen Peinado Cañaveras, María Antonia Berrocal Higuero, Cristina de Miguel Sánchez","doi":"10.1080/15360288.2024.2369542","DOIUrl":"10.1080/15360288.2024.2369542","url":null,"abstract":"The presence of comorbidities and complex drug regimens makes palliative care patients more susceptible to opioid medication errors. Most of the studies conducted so far have mainly focused on patients admitted to hospitals or hospice facilities. During this study, we examined the frequency of medication errors with opioids and the causes and consequences for patients, followed by home palliative care teams. Errors occurred in 39% of patients (n = 378) and 27% of all prescribed opioids (n = 708). Of the 148 (39%) patients with error/s in the opioid/s prescribed, in 55% the patient and/or the caregiver were involved in the error; in 26% the health care providers were involved. An association was found between the presence of error in the prescribed opioid and the level of patient education, p = .038, and with the number of days of follow-up, p < .001. Considering their formulation, the prescribed opioids were associated with medication error, type of error, and cause of the error. The study demonstrated an association between the route of administration and error p < .004, and type of error p < .001.","PeriodicalId":16645,"journal":{"name":"Journal of Pain & Palliative Care Pharmacotherapy","volume":" ","pages":"334-344"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141534620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Teaching People About Pain: A Path to Healing Beyond Medication. 教导人们关于疼痛：一条超越药物治疗的道路。

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Journal of Pain & Palliative Care Pharmacotherapy Pub Date : 2024-12-01 Epub Date: 2024-12-11 DOI: 10.1080/15360288.2024.2436979

Jeff Clyde G Corpuz

引用次数: 0

Intravenous Ketamine for Cancer Pain: A Single-Center Retrospective Analysis Comparing Fixed-Rate Versus Weight-Based Dosing. 静脉注射氯胺酮治疗癌症疼痛：固定剂量与按体重给药的单中心回顾性分析比较。

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Journal of Pain & Palliative Care Pharmacotherapy Pub Date : 2024-12-01 Epub Date: 2024-07-11 DOI: 10.1080/15360288.2024.2374297

Leslie Siegel, Kyle Quirk, Gary Houchard, Sarah Ehrman, Eric McLaughlin, Omar Hajmousa, Maureen Saphire

{"title":"Intravenous Ketamine for Cancer Pain: A Single-Center Retrospective Analysis Comparing Fixed-Rate Versus Weight-Based Dosing.","authors":"Leslie Siegel, Kyle Quirk, Gary Houchard, Sarah Ehrman, Eric McLaughlin, Omar Hajmousa, Maureen Saphire","doi":"10.1080/15360288.2024.2374297","DOIUrl":"10.1080/15360288.2024.2374297","url":null,"abstract":"Although weak evidence exists to support subanesthetic ketamine for cancer pain treatment, successful use may be hindered in the absence of standardized dosing guidance. We aimed to compare the success rates of intravenous ketamine fixed-rate versus weight-based dosing strategies for cancer pain treatment, and to assess patient characteristics that correlate with treatment success. We conducted a single-center retrospective review including non-critically ill adults with cancer pain who received subanesthetic ketamine for at least 24-h. All patients received fixed-rate ketamine; weight-based doses were retrospectively determined using total body weight. Treatment was considered successful if after reaching the maximum prescribed ketamine dose the patient had a 30% reduction in: baseline pain score, as-needed opioid use, or total morphine equivalent daily dose over a standardized 24-h. Of 105 included patients, 51 (48.6%) successfully responded to ketamine. Responders had lower fixed-rate ketamine doses compared to non-responders (median[IQR] 15 mg/hr[10-15] vs. 15 mg/hr[15-20], p = 0.043), but no difference in retrospectively calculated weight-based doses (0.201 ± 0.09 mg/kg/hr vs. 0.209 ± 0.08 mg/kg/hr, p = 0.59). Responders had higher daily opioid requirements at baseline compared to non-responders (p = 0.04). Though underpowered, our findings suggest that weight-based ketamine dosing may not convey additional benefit over fixed-rate dosing.","PeriodicalId":16645,"journal":{"name":"Journal of Pain & Palliative Care Pharmacotherapy","volume":" ","pages":"414-422"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11724009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141590573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Concurrent Use of Opioids and Gabapentin on Fall Risk in Older Adults. 同时使用阿片类药物和加巴喷丁对老年人跌倒风险的影响

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Journal of Pain & Palliative Care Pharmacotherapy Pub Date : 2024-12-01 Epub Date: 2024-06-10 DOI: 10.1080/15360288.2024.2358953

Jacob T Painter, Cheng Peng, Mary Burlette, Callie Clement, Lisa Luciani, Gohar Azhar, Lindsey Dayer

{"title":"The Effect of Concurrent Use of Opioids and Gabapentin on Fall Risk in Older Adults.","authors":"Jacob T Painter, Cheng Peng, Mary Burlette, Callie Clement, Lisa Luciani, Gohar Azhar, Lindsey Dayer","doi":"10.1080/15360288.2024.2358953","DOIUrl":"10.1080/15360288.2024.2358953","url":null,"abstract":"Falls pose a significant threat to older adults, resulting in injuries and mortality. Concurrently prescribed opioids and gabapentin for pain management may increase fall risks in older patients. This study aimed to estimate fall risks associated with the concurrent use of gabapentin and opioids, comparing them to opioid monotherapy in older adults. A retrospective case-control study of 1,813 patients aged 65-89 on chronic opioid therapy (2017-2020), excluding those with a fall history, analysis focused on the first fall occurrence. Logistic regression assessed the association between concurrent gabapentin and opioid use and fall events. Out of eligible patients, 122 (6.73%) experienced falls during opioid therapy, with 232 (12.80%) having concurrent gabapentin use. Concurrent use significantly increased fall risk (AOR = 1.73; 95% CI: 1.08-2.78). Being female, aged ≥81, and having more chronic conditions also increased risk. Mitigating fall risk in older adults requires education on prevention, exploring alternative pain management, and careful consideration of prescribing. Further research is crucial to understand adverse events linked to combined opioid and gabapentin use in the geriatric population.","PeriodicalId":16645,"journal":{"name":"Journal of Pain & Palliative Care Pharmacotherapy","volume":" ","pages":"327-333"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141300803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancing Patient Care Through Clinical Research. 通过临床研究推进患者护理。

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Journal of Pain & Palliative Care Pharmacotherapy Pub Date : 2024-12-01 Epub Date: 2025-03-14 DOI: 10.1080/15360288.2024.2415803

Julie M Waldfogel, Chris Herndon

引用次数: 0

Navigating the Postoperative Management of Remifentanil-Induced Hyperalgesia: A Case Report. 瑞芬太尼诱发的术后痛感处理指南：病例报告。

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Journal of Pain & Palliative Care Pharmacotherapy Pub Date : 2024-12-01 Epub Date: 2024-09-09 DOI: 10.1080/15360288.2024.2400901

Nathan T Smith, Ryan Fernholz, Sanny Juresic

引用次数: 0

Shared Decision-Making and Collaborative Care Models for Pain Management: A Scoping Review of Existing Evidence. 疼痛管理的共同决策与合作护理模式：现有证据范围综述》。

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Journal of Pain & Palliative Care Pharmacotherapy Pub Date : 2024-12-01 Epub Date: 2024-09-12 DOI: 10.1080/15360288.2024.2400925

Elise Omaki, Megan Fitzgerald, Diksha Iyer, Wendy Shields, Renan Castillo

{"title":"Shared Decision-Making and Collaborative Care Models for Pain Management: A Scoping Review of Existing Evidence.","authors":"Elise Omaki, Megan Fitzgerald, Diksha Iyer, Wendy Shields, Renan Castillo","doi":"10.1080/15360288.2024.2400925","DOIUrl":"10.1080/15360288.2024.2400925","url":null,"abstract":"This article aims to summarize the existing evidence on shared decision-making and collaborative care models for acute and chronic pain management. We searched the PubMed database for articles published between 1980 and 2023 and scanned included articles' references to identify additional sources. Two reviewers independently screened titles and abstracts. Studies met inclusion criteria if they implemented or evaluated shared decision-making or collaborative care interventions in patients with acute or chronic pain. A total of 690 articles were reviewed, with 32 full text articles meeting inclusion criteria. Most studies assessed changes in prescription opioid quantities and patient-reported pain levels. Secondary measures generally included patient satisfaction, 30-day refill rate, and use of non-opioid analgesics. Shared decision-making and collaborative care models are promising interventions to improve pain management. These interventions are effective at reducing opioid consumption among acute and chronic pain patients without compromising patient-reported pain levels. There is further research needed to evaluate how shared decision-making and collaborative care interventions impact patient-centered outcomes such as patient satisfaction, quality of life, and patient-provider communication.","PeriodicalId":16645,"journal":{"name":"Journal of Pain & Palliative Care Pharmacotherapy","volume":" ","pages":"394-405"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142289587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Foreigner. 外国人

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Journal of Pain & Palliative Care Pharmacotherapy Pub Date : 2024-12-01 Epub Date: 2024-07-25 DOI: 10.1080/15360288.2024.2383463

Tarek Zieneldien

引用次数: 0