Journal of Orthopaedic Trauma最新文献

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Nine Months of Fluoxetine Aids in the Reduction of Posttraumatic Stress Symptoms following a Traumatic Musculoskeletal Injury: A Randomized Controlled Trial. 9个月氟西汀有助于减轻外伤性肌肉骨骼损伤后的创伤后应激症状:一项随机对照试验
IF 2 3区 医学
Journal of Orthopaedic Trauma Pub Date : 2026-07-13 DOI: 10.1097/BOT.0000000000003243
M Pazik, T Vasilopoulos, L de Faria, Dv Rijo, Mb Horodyski, Ca Mathews, Je Hagen
{"title":"Nine Months of Fluoxetine Aids in the Reduction of Posttraumatic Stress Symptoms following a Traumatic Musculoskeletal Injury: A Randomized Controlled Trial.","authors":"M Pazik, T Vasilopoulos, L de Faria, Dv Rijo, Mb Horodyski, Ca Mathews, Je Hagen","doi":"10.1097/BOT.0000000000003243","DOIUrl":"https://doi.org/10.1097/BOT.0000000000003243","url":null,"abstract":"<p><strong>Objectives: </strong>To determine whether Fluoxetine, prescribed by orthopaedic providers during the immediate post-traumatic period, can lessen post-traumatic stress symptoms in survivors of traumatic musculoskeletal injuries.</p><p><strong>Methods: </strong>Design: Non-Blinded Prospective Randomized Clinical Trial.</p><p><strong>Setting: </strong>Single Academic Level 1 Trauma Center.</p><p><strong>Patient selection criteria: </strong>From July 2021 to December 2023, orthopaedic surgical patients admitted for a high-energy musculoskeletal trauma (injuries not resulting from a ground level fall or less) were randomized to receive 9 months of Fluoxetine (Prozac®) or Placebo (Calcium).</p><p><strong>Outcome measures and comparisons: </strong>Outcomes were collected five times over the course of one year (2 weeks, 6 weeks, 3 months, 6 months, and 12 months). Patient-reported outcome measures evaluated depression (Beck Depression Inventory, BDI-II), anxiety (Beck Anxiety Inventory, BAI), Post-Traumatic Stress Disorder (PTSD) (PTSD Scale-Self report for DSM-5, PSS-SR), sleep (Pittsburgh Sleep Quality Index, PSQI), pain ( Pain, Enjoyment, General Activity Scale, PEG), and social enjoyment (PROMIS - Ability to participate Social, and PROMIS - Social Isolation ).</p><p><strong>Results: </strong>The two groups (Fluoxetine = 33, Calcium = 35) were similar in terms of age (Fluoxetine = 43.5 years (SD 15.8, range = 18-73), Calcium = 40.3 years (SD 17.7, range18-70 )) and sex (Fluoxetine =14 females, Calcium = 15 females). Subjects randomized to fluoxetine showed an improvement in PTSD symptoms over time (estimate = -0.2, 95%: -0.4, -0.0; with negative numbers indicating lessening symptoms), while those randomized to calcium exhibited little to no change (estimate = 0.1, 95%: -0.1, 0.3). Additionally, subjects in the fluoxetine group (estimate = -0.1, 95% CI: -0.1, -0.0, negative numbers indicating a decrease in pain) showed a significant improvement in pain over time, whereas the calcium group showed no significant change (estimate = -0.0, 95% CI: -0.0, 0.0). There were no significant changes over time in BDI scores (F1,159 = 0.0, p = 0.9), BAI scores (F1,169.4 = 0.0, p = 0.9), or PROMIS measure Social Isolation (F1,142.9 = 0.5, p = 0.5).</p><p><strong>Conclusions: </strong>Nine months of fluoxetine following a traumatic musculoskeletal injury decreased the severity of post-traumatic stress symptoms and pain throughout the recovery period.</p><p><strong>Level of evidence: </strong>Level II.</p>","PeriodicalId":16644,"journal":{"name":"Journal of Orthopaedic Trauma","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148436932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medializing the Reaming Entry Point for Pertrochanteric Femur Fractures Treated with Cephalomedullary Nails: A Technical Trick. 髓内钉治疗股骨粗隆骨折的扩孔切入点:一个技术技巧。
IF 2 3区 医学
Journal of Orthopaedic Trauma Pub Date : 2026-07-07 DOI: 10.1097/BOT.0000000000003248
Christopher R Leland, Healy S Vise, Austin T Gregg, Adam N Musick, Arun Aneja
{"title":"Medializing the Reaming Entry Point for Pertrochanteric Femur Fractures Treated with Cephalomedullary Nails: A Technical Trick.","authors":"Christopher R Leland, Healy S Vise, Austin T Gregg, Adam N Musick, Arun Aneja","doi":"10.1097/BOT.0000000000003248","DOIUrl":"https://doi.org/10.1097/BOT.0000000000003248","url":null,"abstract":"","PeriodicalId":16644,"journal":{"name":"Journal of Orthopaedic Trauma","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148405113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An analysis of risk factors for failure after operative treatment of displaced femoral neck fractures in patients 18-60 years of age. 18-60岁移位性股骨颈骨折手术治疗失败的危险因素分析。
IF 2 3区 医学
Journal of Orthopaedic Trauma Pub Date : 2026-07-02 DOI: 10.1097/BOT.0000000000003244
Erika Roddy, Zachary Rockov, Reza Firoozabadi
{"title":"An analysis of risk factors for failure after operative treatment of displaced femoral neck fractures in patients 18-60 years of age.","authors":"Erika Roddy, Zachary Rockov, Reza Firoozabadi","doi":"10.1097/BOT.0000000000003244","DOIUrl":"https://doi.org/10.1097/BOT.0000000000003244","url":null,"abstract":"<p><strong>Objectives: </strong>To identify risk factors for failure after operative treatment of displaced femoral neck fractures in patients 60 years of age and younger.</p><p><strong>Methods: </strong>Design: Retrospective cohort study.</p><p><strong>Setting: </strong>Single level 1 academic trauma center.</p><p><strong>Patient selection criteria: </strong>All patients ages 18-60 years who underwent operative fixation of a displaced femoral neck fracture (AO/OTA 31B) between 2005 and 2024 were eligible for inclusion. Patients who were lost to follow-up prior to 6 months, or who had clear indications for hemiarthroplasty but underwent fixation due to medical and or social circumstances, were excluded.</p><p><strong>Outcome measures and comparisons: </strong>The primary outcome was treatment failure, defined as femoral neck nonunion/fixation failure, development of avascular necrosis (AVN), and/or malunion (shortening ≥ 15mm or varus angulation). Patient, injury, and treatment factors were examined as risk factors for failure.</p><p><strong>Results: </strong>Two hundred and twenty-three patients were included. The average age was 39 years (SD 12, range 18-60) and 78% were male. The rates of nonunion/fixation failure, AVN, and malunion were 13%, 19%, and 5%, respectively. The overall failure rate was 30%. In multivariable analysis, increased initial fracture displacement (OR 7.1, 95% CI 1.5-33.5, p=0.013), treatment with cannulated screws versus a fixed angle implant (OR 3.7, 95% CI 1.4-10.0, p=0.009), and good (rather than excellent) reduction (OR 5.6, 95% CI 2.0-15.7, p=0.001) were independently associated with nonunion/fixation failure. In multivariable analysis, medial fracture exit <1cm from the cranial edge of the lesser trochanter was associated with a decreased risk of AVN (OR 0.13, 95% CI 0.03-0.64, p=0.011), while increasing age (OR 1.07, 95% CI 1.01-1.15, p=0.036) and low energy mechanism (OR 9.5, 95% CI 2.4-38.6, p=0.002) were associated with increased risk of malunion. In univariable analysis, treatment with a static vs dynamic implant was not associated with risk of AVN, nonunion/fixation failure, or malunion (p>0.05 for all).</p><p><strong>Conclusions: </strong>In patients aged 18-60 with displaced femoral neck fractures treated with operative fixation, the overall failure rate (including AVN, nonunion, and malunion) was 30%. Medial fracture exit < 1cm from the cranial edge of the lesser trochanter was protective against the development of AVN. Increased initial fracture displacement, treatment with non-fixed angle implants, and achieving only good (rather than excellent) reduction were independently associated with increased risk of nonunion.</p><p><strong>Level of evidence: </strong>III.</p>","PeriodicalId":16644,"journal":{"name":"Journal of Orthopaedic Trauma","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148376104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Uncorrected Preoperative Malnutrition Is Associated with Worse Outcomes After Operative Fixation of Diaphyseal Tibial Fractures. 术前未纠正的营养不良与胫骨骨干骨折手术固定后较差的预后相关。
IF 2 3区 医学
Journal of Orthopaedic Trauma Pub Date : 2026-07-02 DOI: 10.1097/BOT.0000000000003246
Daniel E Pereira, Lane McCoy, Noah J Harrison, Kellie Bushe, Travis Kotzur, Christopher McAndrew, Marschall Berkes, Mitchel Obey, Jenna-Leigh Wilson
{"title":"Uncorrected Preoperative Malnutrition Is Associated with Worse Outcomes After Operative Fixation of Diaphyseal Tibial Fractures.","authors":"Daniel E Pereira, Lane McCoy, Noah J Harrison, Kellie Bushe, Travis Kotzur, Christopher McAndrew, Marschall Berkes, Mitchel Obey, Jenna-Leigh Wilson","doi":"10.1097/BOT.0000000000003246","DOIUrl":"https://doi.org/10.1097/BOT.0000000000003246","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;To evaluate whether serum markers of malnutrition were associated with postoperative complications after tibial shaft fracture fixation, and whether postoperative correction mitigates this risk.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Design: Retrospective cohort study.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Setting: &lt;/strong&gt;Multicenter (50 healthcare centers; North American national database).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Patient selection criteria: &lt;/strong&gt;Adult patients ≥18 years of age undergoing fixation of tibial shaft fractures (OTA/AO 42) between January 1, 2013, and December 31, 2022, with a minimum of one year of follow-up were included. Patients with a history of malignancy or Gustilo-Anderson type III open fractures were excluded from the study.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Outcomes measures and comparisons: &lt;/strong&gt;The primary outcome was the occurrence of postoperative complications. Patients with serum markers for malnutrition were compared to matched controls. Malnourished patients with subsequently normalized serum markers were compared to previously matched healthy cohorts and cohorts with persistent malnutrition.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Following matching, a total of 10,722 patients were included for primary analysis: 5,361 malnourished patients with mean age 52 (range 18-90), 53.6% male and 5,361 control with mean age 53.2 (range 18-90) with 52.9% male. Preoperative malnutrition was associated with significantly higher rates of postoperative complications, including nonunion (RR=1.4), revision surgery (RR&gt;1.4), infection (RR&gt;2.0), failure of fixation (RR=1.3), thromboembolic events (RR&gt;2.0), and sepsis (RR&gt;2.0) (all p &lt; 0.001). Among patients with preoperative malnutrition, those with uncorrected postoperative serum markers demonstrated higher risks of nonunion, revision, infection, and implant failure compared to those with serum markers that were corrected postoperatively (RR&gt;2.0, all p&lt;0.001). However, when compared to patients with normal preoperative nutrition values, individuals with postoperatively corrected malnutrition remained at increased risk for revision and infection (RR&gt;1.4, all p=0.002) but not nonunion (6.5% vs. 5.6%, p&gt;0.05) or failure of fixation (4.6% vs. 4.1%, p&gt;0.05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Malnutrition was associated with adverse surgical outcomes following tibial shaft fracture fixation, with significantly higher rates of nonunion, revision procedures, infection, wound complications, thromboembolic events, and medical morbidity compared with patients with normal preoperative nutrition. Postoperative correction of nutritional deficiencies reduced complication risk; however, residual risk remained elevated relative to patients with normal preoperative nutritional markers. These findings highlight malnutrition as a partially modifiable risk factor in tibial shaft fracture repair and support nutritional optimization as a part of postoperative management to improve patient outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Level of evidence:","PeriodicalId":16644,"journal":{"name":"Journal of Orthopaedic Trauma","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148376065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor Regarding "Proton Pump Inhibitors Are Associated With Increased Risk of Site-Specific Nonunion After Open Reduction Internal Fixation". 致编辑的关于“质子泵抑制剂与开放性复位内固定术后部位特异性骨不连风险增加有关”的信。
IF 2 3区 医学
Journal of Orthopaedic Trauma Pub Date : 2026-07-01 DOI: 10.1097/BOT.0000000000003171
Orhan Ayas, Alaeddin Acar
{"title":"Letter to the Editor Regarding \"Proton Pump Inhibitors Are Associated With Increased Risk of Site-Specific Nonunion After Open Reduction Internal Fixation\".","authors":"Orhan Ayas, Alaeddin Acar","doi":"10.1097/BOT.0000000000003171","DOIUrl":"10.1097/BOT.0000000000003171","url":null,"abstract":"","PeriodicalId":16644,"journal":{"name":"Journal of Orthopaedic Trauma","volume":"40 7","pages":"e172"},"PeriodicalIF":2.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148226117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Fixation Enhances Discharge Independence in Elderly Patients With Fragility Fractures of the Pelvis. 手术内固定提高老年骨盆脆性骨折患者的出院独立性。
IF 2 3区 医学
Journal of Orthopaedic Trauma Pub Date : 2026-07-01 DOI: 10.1097/BOT.0000000000003238
Nicholas F Quercetti, Steve DiStefano, Michael Yayac, Paul G Mastrokostas, John Getchell, Mitchell K Ng
{"title":"Surgical Fixation Enhances Discharge Independence in Elderly Patients With Fragility Fractures of the Pelvis.","authors":"Nicholas F Quercetti, Steve DiStefano, Michael Yayac, Paul G Mastrokostas, John Getchell, Mitchell K Ng","doi":"10.1097/BOT.0000000000003238","DOIUrl":"https://doi.org/10.1097/BOT.0000000000003238","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate outcomes following surgical and nonsurgical management of fragility fractures of the pelvis (FFP) in elderly patients, focusing on pain relief, hospital course, complications, and discharge disposition.</p><p><strong>Methods: </strong>Design: Retrospective cohort study.</p><p><strong>Setting: </strong>Single Level I trauma center.</p><p><strong>Patient selection criteria: </strong>All patients aged 60 years and older treated for low-energy FFP (OTA/AO 61-A/B/C) between 2018 and 2022 by one fellowship-trained orthopaedic trauma surgeon were included. Patients with high-energy mechanisms, polytrauma, and non-osteoporotic pathologic fractures were excluded.</p><p><strong>Outcome measures and comparisons: </strong>Visual analog scale (VAS) pain scores at admission and discharge, hospital length of stay (LOS), in-hospital and 90-day complications, and discharge destination were compared among nonoperative, acute fixation, and delayed fixation cohorts. Acute fixation was defined as fixation during the index hospitalization, regardless of whether surgery was planned at admission or performed after failed inpatient mobilization. Delayed fixation was defined as fixation after discharge following initial nonoperative management.</p><p><strong>Results: </strong>132 patients were included, including 56 managed nonoperatively and 76 treated operatively (55 acutely, 21 delayed). Patients treated nonoperatively were older than those treated operatively (84.1±8.28 vs 77.1±9.48 years, P<0.005), while the proportion of female patients was similar between groups (91.1% vs 84.2%, P=0.300). Admission VAS pain scores were 6.4, 6.3, and 5.9 for the acute fixation, delayed fixation, and nonoperative groups, respectively, and discharge VAS scores were 3.0, 3.6, and 3.4, with no significant differences between groups (P>0.05). Postoperative LOS, defined as the hospital stay associated with definitive treatment and excluding any prior index admission for delayed fixation patients, was longest after acute fixation (9.7 days) compared with delayed fixation (2.8 days) and nonoperative treatment (5.2 days, P<0.05). Discharge disposition differed, with home discharge occurring in 27.3% of acutely fixed patients, 76.2% of delayed fixation patients, and 14.3% managed nonoperatively (P<0.05), with disposition defined at discharge from the hospitalization associated with definitive treatment. Discharge home was approximately threefold higher in the operative cohort than nonoperative cohort (40.8% versus 14.3%, P<0.05).</p><p><strong>Conclusions: </strong>Percutaneous fixation of FFP was associated with greater likelihood of discharge home without increased complications. Acute fixation was associated with longer LOS.</p><p><strong>Level of evidence: </strong>Level III, retrospective comparative study.</p>","PeriodicalId":16644,"journal":{"name":"Journal of Orthopaedic Trauma","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148368699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comprehensive Guide to Tibial Nailing Systems for Short Segment Nailing Procedures. 胫骨短节段钉入系统综合指南。
IF 2 3区 医学
Journal of Orthopaedic Trauma Pub Date : 2026-07-01 DOI: 10.1097/BOT.0000000000003239
Youssef M Khalafallah, Beatrice A Morrow, Douglas R Dirschl
{"title":"A Comprehensive Guide to Tibial Nailing Systems for Short Segment Nailing Procedures.","authors":"Youssef M Khalafallah, Beatrice A Morrow, Douglas R Dirschl","doi":"10.1097/BOT.0000000000003239","DOIUrl":"https://doi.org/10.1097/BOT.0000000000003239","url":null,"abstract":"<p><strong>Objective: </strong>To characterize and compare interlocking screw configurations and design specifications of commercially available tibial intramedullary nail systems used for short segment fixation.</p><p><strong>Methods: </strong>Data were collected in November 2025 from publicly available product information on manufacturer websites for tibial intramedullary nail systems marketed in the United States. Manufactures were identified based on established presence in the United States orthopedic implant market, including vendors listed at the 2025 Orthopaedic Trauma Association annual meeting. When required information was not publicly available, additional details were obtained through direct communication with manufacturer representatives via email correspondence and product specialists. Tibial nail systems were included if they were actively marketed and available for clinical use in the United States at the time of data collection. For each system, data were collected on interlocking screw hole quantity and position, nail diameter, total length, and relavant design features.</p><p><strong>Results: </strong>Thirteen tibial nailing systems were identified from ten manufacturers were identified and analyzed. Interlocking screw configurations varied across systems, with 3 to 5 proximal screws and 3 to 5 distal screws available, as well as differences in screw number and spatial distribution. Nail diameters, available lengths, and additional design features also varied among systems. The shortest proximal distance from the nail tip to the center of the second interlocking screw hole was 17mm and the shortest distal distance was 12mm.</p><p><strong>Conclusions: </strong>This study provided a detail comparison of tibial nailing systems available in the United States, offering valuable information on nail specifications and screw positions. A comprehensive table and graphic representation serves as a practical planning resource for surgeons in the operative management of short segment distal tibial fractures, enhancing the selection of optimal implants for personalized patient care.</p><p><strong>Level of evidence: </strong>V.</p>","PeriodicalId":16644,"journal":{"name":"Journal of Orthopaedic Trauma","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148368808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breaking Down the Evidence: A Multicenter Analysis of Venous Thromboembolism Among Trauma Patients with Lower Extremity Fractures. 打破证据:下肢骨折创伤患者静脉血栓栓塞的多中心分析。
IF 2 3区 医学
Journal of Orthopaedic Trauma Pub Date : 2026-07-01 DOI: 10.1097/BOT.0000000000003174
Lisa M Knowlton, Jacob G Guorgui, Simeng Wang, Katherine Arnow, M Margaret Knudson
{"title":"Breaking Down the Evidence: A Multicenter Analysis of Venous Thromboembolism Among Trauma Patients with Lower Extremity Fractures.","authors":"Lisa M Knowlton, Jacob G Guorgui, Simeng Wang, Katherine Arnow, M Margaret Knudson","doi":"10.1097/BOT.0000000000003174","DOIUrl":"10.1097/BOT.0000000000003174","url":null,"abstract":"<p><strong>Objectives: </strong>To determine whether chemoprophylaxis initiation within 24 hours reduces venous thromboembolism (VTE) risk among trauma patients with lower extremity long bone fractures.</p><p><strong>Methods: </strong></p><p><strong>Design: </strong>This was a retrospective cohort study.</p><p><strong>Setting: </strong>Seventeen Level I trauma centers as a part of the Consortium of Leaders in the Study of Traumatic Thromboembolism study group.</p><p><strong>Patient selection criteria: </strong>Patients aged 18-40 years with a diagnosis of lower extremity long bone fracture between January 1, 2018, and December 31, 2020, were included.</p><p><strong>Outcome measures and comparisons: </strong>Primary outcome was VTE during admission. Patients were compared based on VTE chemoprophylaxis initiation within 24 hours (early prophylaxis, E-PROPH) versus not (late or no prophylaxis, L-PROPH) using inverse probability weighted Cox survival analysis.</p><p><strong>Results: </strong>In total, 120 (5.3%) among 2264 patients with lower extremity fractures developed VTE. 57.5% received E-PROPH and 42.5% received L-PROPH. The E-PROPH group had fewer patients with an injury severity score ≥16 (30.3% vs. 52.4%, P < 0.001) and a lower proportion of associated head injury (8.1% vs. 26.7%, P < 0.001). VTE incidence was significantly higher in the L-PROPH group than in the E-PROPH group (8.6% vs. 2.8%, P < 0.001). In the adjusted model, E-PROPH was independently associated with nearly a half reduction in VTE incidence (hazard ratio: 0.54, 95% confidence interval, 0.34-0.85). There was no significant difference in the adjusted bleeding complication model (aOR 1.84; 95% confidence interval, 0.75-4.57).</p><p><strong>Conclusion: </strong>VTE chemoprophylaxis within the first 24 hours of admission was associated with a marked reduction in VTE incidence among patients with traumatic lower extremity long bone fractures without increase in bleeding risks.</p><p><strong>Level of evidence: </strong>Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.</p>","PeriodicalId":16644,"journal":{"name":"Journal of Orthopaedic Trauma","volume":" ","pages":"e164-e170"},"PeriodicalIF":2.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147633713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minimally Invasive Screw Fixation of Olecranon Fractures. 鹰嘴骨折的微创螺钉固定。
IF 2 3区 医学
Journal of Orthopaedic Trauma Pub Date : 2026-07-01 DOI: 10.1097/BOT.0000000000003240
Celso Ricardo Folberg, Tiago Zimerman, Jairo André de Oliveira Alves, Fernando Maurente Sirena Pereira, Carlos Roberto Galia
{"title":"Minimally Invasive Screw Fixation of Olecranon Fractures.","authors":"Celso Ricardo Folberg, Tiago Zimerman, Jairo André de Oliveira Alves, Fernando Maurente Sirena Pereira, Carlos Roberto Galia","doi":"10.1097/BOT.0000000000003240","DOIUrl":"https://doi.org/10.1097/BOT.0000000000003240","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the indications, clinical outcomes, and complications of a minimally invasive technique using intramedullary screw fixation for the treatment of olecranon fractures.</p><p><strong>Methods: </strong>Design: Retrospective case series.</p><p><strong>Setting: </strong>Single-center academic hospital.</p><p><strong>Patient selection criteria: </strong>Adult patients with closed Mayo type IA, IB, IIA, or IIB olecranon fractures (OTA/AO 2U1B1d[1], 2U1B1e[1], 2U1B1d[2], or 2U1B1e[2]) treated surgically with a minimally invasive intramedullary screw osteosynthesis technique between December 2017 and April 2023 were included. Fractures with high comminution, fracture-dislocations, associated vascular or nerve injury, previous elbow surgery or traumatic injury affecting the ipsilateral elbow, and inadequate follow-up were excluded.</p><p><strong>Outcome measures and comparisons: </strong>Primary outcomes included the Mayo Elbow Performance Score (MEPS), elbow range of motion (ROM), and complications. Major intraoperative complications were defined as neurovascular injuries, intraoperative clinical emergencies, iatrogenic comminution, or unplanned conversion to another fixation technique. No control group was included.</p><p><strong>Results: </strong>A total of 31 patients were included. Mean age was 54.3 years (range 21-87 years), and 19 patients (61.29%) were female. The median follow-up was 35 months (range 12-77 months). The median time from trauma to surgery was 11 days (range 3-17 days). 30 patients achieved good or excellent scores in the MEPS. The median flexion-extension arc of motion was 130° (interquartile range: 120-140°), with 28 of 31 patients achieving 100° or more. No major intraoperative complications or infections occurred. One patient (3.2%) presented loss of reduction and screw migration. Three patients (9.7%) required reintervention, one for early loss of reduction and two for symptomatic hardware removal.</p><p><strong>Conclusions: </strong>Minimally invasive olecranon osteosynthesis using an intramedullary screw demonstrated good functional outcomes and a low complication rate for undisplaced fractures.</p><p><strong>Level of evidence: </strong>IV.</p>","PeriodicalId":16644,"journal":{"name":"Journal of Orthopaedic Trauma","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148368475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to the Letter to the Editor Regarding "Proton Pump Inhibitors Are Associated With Increased Risk of Site-specific Nonunion After Open Reduction Internal Fixation". 关于“质子泵抑制剂与开放性复位内固定术后部位特异性骨不连风险增加相关”的致编辑信的回复。
IF 2 3区 医学
Journal of Orthopaedic Trauma Pub Date : 2026-07-01 DOI: 10.1097/BOT.0000000000003168
Melissa Romoff, Michael S Kim, John A Scolaro
{"title":"Response to the Letter to the Editor Regarding \"Proton Pump Inhibitors Are Associated With Increased Risk of Site-specific Nonunion After Open Reduction Internal Fixation\".","authors":"Melissa Romoff, Michael S Kim, John A Scolaro","doi":"10.1097/BOT.0000000000003168","DOIUrl":"10.1097/BOT.0000000000003168","url":null,"abstract":"","PeriodicalId":16644,"journal":{"name":"Journal of Orthopaedic Trauma","volume":" ","pages":"e172-e173"},"PeriodicalIF":2.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147433628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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