Journal of Pain and Relief最新文献

Support of Acute Pain Therapy by Analgesia Nociception Index in Post Anesthesia Care Unit: A Randomized Controlled Trial 麻醉后护理病房镇痛痛觉指数对急性疼痛治疗的支持:一项随机对照试验

Journal of Pain and Relief Pub Date : 2019-03-20 DOI: 10.4172/2167-0846.1000343

N. Hochhausen, M. Ritter, Andreas Follmann, Henriette Dohmeier, R. Rossaint, M. Czaplik

{"title":"Support of Acute Pain Therapy by Analgesia Nociception Index in Post Anesthesia Care Unit: A Randomized Controlled Trial","authors":"N. Hochhausen, M. Ritter, Andreas Follmann, Henriette Dohmeier, R. Rossaint, M. Czaplik","doi":"10.4172/2167-0846.1000343","DOIUrl":"https://doi.org/10.4172/2167-0846.1000343","url":null,"abstract":"Objective: Postoperative pain management requires a well-directed pain therapy. Generally, the assessment of pain intensity depends on a self-evaluated numeric rating scale (NRS, 0 to 10). Recently, a pain monitor using a socalled “ANI” (analgesia nociception index; 100 to 0) was introduced. The higher the ANI, the lower the pain intensity is considered. The aim of this study was to investigate if the use of ANI improves acute pain therapy in the post anesthesia care unit (PACU) by means of the experienced pain intensity (mean NRS) as the primary outcome parameter.Methods: After admission to PACU, patients were randomly assigned to the “supported by technique” (TC) or the control group (CO). In both groups, self-assessment of pain intensity was requested every 15 minutes and pain therapy was provided according to internal clinical standards when the self-reported NRS by the patient exceeded 4. In the TC group, NRS pain score was additionally assessed when ANI fell below 50.Results: Out of 91 collectively included patients, 46 were assigned to the TC group. The mean NRS did not differ between the groups (p=0.192) at discharge. However, suitability of the ANI monitor was strongly dependent from the individual patient. In some patients, a strong negative correlation was obtained, in other patients no correlation or, curiously, a strong positive correlation was observed.Conclusion: Although objective pain intensity assessment would be beneficial for postoperative care, its measurement remains challenging.","PeriodicalId":16641,"journal":{"name":"Journal of Pain and Relief","volume":"144 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73449734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurogenic information in autoimmune diseases and chronic pain syndromes 自身免疫性疾病和慢性疼痛综合征的神经源性信息

Journal of Pain and Relief Pub Date : 2018-11-26 DOI: 10.4172/2167-0846-C1-020

pMatthias Seidelp

引用次数: 1

Adipose-derived Mesenchymal Stem Cells Improve Spontaneous Pain in a Rat Model of Neuropathic Pain 脂肪来源的间充质干细胞改善大鼠神经性疼痛模型中的自发性疼痛

Journal of Pain and Relief Pub Date : 2018-05-22 DOI: 10.4172/2167-0846.1000320

M. Imanishi, H. Asato, Kohei Umekawa, S. Sasaki, Tetsuji Terashima

{"title":"Adipose-derived Mesenchymal Stem Cells Improve Spontaneous Pain in a Rat Model of Neuropathic Pain","authors":"M. Imanishi, H. Asato, Kohei Umekawa, S. Sasaki, Tetsuji Terashima","doi":"10.4172/2167-0846.1000320","DOIUrl":"https://doi.org/10.4172/2167-0846.1000320","url":null,"abstract":"Background: Several studies have investigated the efficacy of transplanting adipose-derived mesenchymal stem cells (ADMSC) in the treatment of neuropathic pain in animals. However, these studies evaluated the effects of transplantation by measuring stimulus-induced pain but not spontaneous pain. Evaluation of spontaneous pain is essential for assessing neuropathic pain in clinical practice, using such measures as the visual analogue scale (VAS). Therefore, spontaneous pain should be evaluated even at the animal experiments stage to verify the efficacy of ADMSC transplantation for treating neuropathic pain. Here, we verify whether ADMSC transplantation improves spontaneous pain in a rat model of neuropathic pain induced by chronic constriction injury of the sciatic nerve. \u0000Methods: ADMSC were isolated from rat adipose tissue and propagated in culture. One week after CCI model rats were generated, ADMSC were transplanted into the epineurium of the area of nerve damage. The effects of transplantation were evaluated by automatically measuring the number of spontaneous pain-related behaviors and quantifying the degree of mechanical allodynia using the von-Frey filament test. A total of 20 F344 rats were used in these experiments. \u0000Results: ADMSC transplantation significantly reduced the number of spontaneous pain-related behaviors and significantly alleviated mechanical allodynia from 21 and 7 days after transplantation, respectively. No animals died during the experiments, and all animals gained weight over the course of the study. \u0000Conclusion: ADMSC transplantation improved not only stimulus-induced pain but also spontaneous pain. ADMSC transplantation may be an effective treatment for neuropathic pain in clinical practice.","PeriodicalId":16641,"journal":{"name":"Journal of Pain and Relief","volume":"2 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81063592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is Paravertebral Block More Effective in Thoracotomy Patients Compared to Thoracic Epidural Block 椎旁阻滞比胸段硬膜外阻滞更有效吗

Journal of Pain and Relief Pub Date : 2018-05-07 DOI: 10.4172/2167-0846.1000317

M. Bakry, Hisham Mohamed Mohamed Salem

{"title":"Is Paravertebral Block More Effective in Thoracotomy Patients Compared to Thoracic Epidural Block","authors":"M. Bakry, Hisham Mohamed Mohamed Salem","doi":"10.4172/2167-0846.1000317","DOIUrl":"https://doi.org/10.4172/2167-0846.1000317","url":null,"abstract":"Purpose: Paravertebral block (PVB) is a simple and safe technique that can be more efficacious than epidural block (EPB) in controlling postoperative pain. We aimed to confirm this by comparing the two methods in patients after thoracotomy. \u0000Methods: Patients were randomly divided into two groups, PVB or EPB (n=30 in each). Vital signs and the visual analog scale (VAS) were evaluated before giving the block then 30 minutes and 3, 6, 9 and 12 hours after thoracotomy. Complications and need for additional analgesic agents were also scrutinized. \u0000Results: The most significant finding was better preservation of pulmonary function tests at most time points in the PVB group (<0.05). VAS scores trended to be better in the PVB group, but the difference was significant only at 30 minutes after giving the block. There were no significant differences between the groups in the incidence of complications or the need for additional analgesic agents. \u0000Conclusion: Paravertebral and epidural blocks are effective in a similar degree in controlling post-operative pain but paravertebral block is safer and more tolerable for the patients.","PeriodicalId":16641,"journal":{"name":"Journal of Pain and Relief","volume":"405 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2018-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79759789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sphenopalatine Ganglion Block for Postdural Puncture Headache 蝶腭神经节阻滞治疗硬脊膜穿刺后头痛

Journal of Pain and Relief Pub Date : 2018-04-04 DOI: 10.4172/2167-0846.1000315

C. Antunes, Tiago Jesus, Sara Ferreira, A. Coutinho, J. Magalhães

{"title":"Sphenopalatine Ganglion Block for Postdural Puncture Headache","authors":"C. Antunes, Tiago Jesus, Sara Ferreira, A. Coutinho, J. Magalhães","doi":"10.4172/2167-0846.1000315","DOIUrl":"https://doi.org/10.4172/2167-0846.1000315","url":null,"abstract":"Post-dural puncture headache (PDPH) is a relatively common complication associated with neuraxial anesthesia and unintentional dural puncture. Epidural blood-patch (EBP) is the gold standard treatment when conservative therapy fails, but has significant risks associated. Recently, bilateral sphenopalatine ganglion block (SPGB) has emerged as an alternative and safe technique in patients with PDPH. Although, there are still few cases reported in the literature. The authors describe two cases of PDPH with resolution after performance of bilateral SPGB. Case 1: Male, submitted to knee arthroplasty under a combined neuraxial anesthesia, with accidental dural puncture with a Tuohy needle. On the third postoperative day, the patient reported frontal headache, exacerbated by orthostatism. The authors performed a bilateral transnasal SPGB and the patient reported clinical improvement, being discharged the next day without any symptoms. Case 2: Pregnant in labor. Epidural space approach with accidental dural puncture. On the second day postpartum, she started with PDPH symptoms, being decided conservative treatment. Two days later, the authors opt to perform a bilateral SPGB. After that, the puerpera has complete relief, being discharged 24 hours later. SPGB, although widely described in the control of headache in the context of chronic pain, has gained increasing interest for the treatment of PDPH because it is a safe and effective technique. In the literature, however, there are few reports of its use in the treatment of PDPH. The two cases described suggest a simple, minimally invasive use and with great potential in the treatment of PDPH.","PeriodicalId":16641,"journal":{"name":"Journal of Pain and Relief","volume":"249 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2018-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82540632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Taxane-Induced Neuropathic Pain: Current Evidence and Treating Strategies 紫杉烷引起的神经性疼痛:目前的证据和治疗策略

Journal of Pain and Relief Pub Date : 2018-03-22 DOI: 10.4172/2167-0846.1000311

V. Pota, M. Passavanti, P. Sansone, M. Barbarisi, M. Pace, C. Aurilio

引用次数: 1

Dexmedetomedine-As an Adjuvant to Epidural Analgesia: Comparison Between Different Doses 右美托美啶作为硬膜外镇痛的辅助剂:不同剂量的比较

Journal of Pain and Relief Pub Date : 2018-03-04 DOI: 10.4172/2167-0846.1000310

M. Boules

{"title":"Dexmedetomedine-As an Adjuvant to Epidural Analgesia: Comparison Between Different Doses","authors":"M. Boules","doi":"10.4172/2167-0846.1000310","DOIUrl":"https://doi.org/10.4172/2167-0846.1000310","url":null,"abstract":"Background: Epidural analgesia offers superior pain relief and early mobilization, especially when a local anesthetic [LA] dose is combined with an adjuvant vs. an LA alone. \u0000Objective: The current study compares the analgesic and anesthetic efficiency of dexmedetomidine (1 and 2 μgkg-1) and levobupivacaine, as well as their respective side effects. \u0000Materials and methods: This study was conducted on a total of 60 ASA I-II patients aged between 20 and 70 years, who underwent elective lower limb operations. The patients that received 1 μgkg-1 dexmedetomidine plus levobupivacaine were assigned to Group 1 (n=30) and those that received 2 μgkg-1 dexmedetomidine plus levobupivacaine to Group 2 (n=30). \u0000Results: Group 2 showed a significantly shortened onset time of sensory block, time needed for maximum sensory level and prolonged duration of anesthesia. Postoperatively, the total dose of levobupivacaine used was significantly lower, patients experienced a higher level of sedation and postoperative analgesia. However, Bradycardia and hypotension were more pronounced in Group 2 patients. \u0000Conclusion: Dexmedetomedine 2 μgkg-1 as an adjuvant to epidural analgesia significantly prolonged the duration of anesthesia and provided excellent sedation and postoperative analgesia. Therefore, higher doses of epidural dexmedetomedine are recommended in long surgical operations to avoid delayed motor recovery, bradycardia and hypotension.","PeriodicalId":16641,"journal":{"name":"Journal of Pain and Relief","volume":"1 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90037306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acupuncture and Auriculotherapy for Severe Pain Following Total Hip Replacement 全髋关节置换术后严重疼痛的针灸和耳廓疗法

Journal of Pain and Relief Pub Date : 2018-01-01 DOI: 10.4172/2167-0846.1000328

U. Hariharan, J. Doval

引用次数: 0

Effects of Superficial and Deep Dry Needling on Pain and Muscle Thickness in Subject with Upper Trapezius Muscle Myofascial Pain Syndrome 干针刺对上斜方肌肌筋膜疼痛综合征患者疼痛和肌肉厚度的影响

Journal of Pain and Relief Pub Date : 2018-01-01 DOI: 10.4172/2167-0846.1000322

J. Sarrafzadeh, Saemeh Khani, K. Ezzati, I. Takamjani

{"title":"Effects of Superficial and Deep Dry Needling on Pain and Muscle Thickness in Subject with Upper Trapezius Muscle Myofascial Pain Syndrome","authors":"J. Sarrafzadeh, Saemeh Khani, K. Ezzati, I. Takamjani","doi":"10.4172/2167-0846.1000322","DOIUrl":"https://doi.org/10.4172/2167-0846.1000322","url":null,"abstract":"Background: Dry needling is one of the main therapeutic approaches in patients with Myofascial pain syndrome. Few studies have been compared the superficial and deep dry needling methods in these patients. Objective: To evaluate the effects of superficial and deep dry needling on pain and muscle thickness in subjects with upper trapezius myofascial pain syndrome. Design: A randomized quasi-experimental double-blinded trial. Methods: 50 subjects with upper trapezius myofascial pain syndrome (age=26/08 ± 4/62, weight=63/88 ± 8/71 kg, height=167/7 ± 4/82 cm, pain duration=9/75 ± 7/05 m) randomly assigned to the superficial (n=25) and deep (n=25) dry needling groups. The pain and maximum thickness of upper trapezius muscle in rest, fair and normal contractions were measured by visual analogue scale (VAS) and an ultrasound device respectively before and after the intervention as well as 7 and 15 days follow-up. Results: The mixed-model ANOVAs revealed a significant group-by-time interaction (F=44.03, p<0.001) for pain and muscle thickness in rest (F=67.00, p<0.001), fair (F=108.73, p<0.001) and normal contraction (F=17.73, p<0.001). The main effects of group and time were statistically significant for pain, rest, fair and normal muscle thickness (p<0.001). There were not any significant differences in rest, fair and normal muscle thickness after intervention as well as 7 and 15 days follow-up. Conclusion: Both superficial and deep dry needling techniques induced significant short-term changes in the VAS. Muscle thickness in rest, fair and normal contractions did not show any significant changes between the groups.","PeriodicalId":16641,"journal":{"name":"Journal of Pain and Relief","volume":"13 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74773176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Nursing in the Attention of the Evaluation of Pain as a 5th Vital Sign 疼痛作为第五生命体征评价的护理注意

Journal of Pain and Relief Pub Date : 2018-01-01 DOI: 10.4172/2167-0846.1000312

Bruno Vilas Boas Dias, Jhenifer Luana dos Santos Camara, Bruno Oliveira Prado, Jean Jhonys Beraldes Cesar

{"title":"Nursing in the Attention of the Evaluation of Pain as a 5th Vital Sign","authors":"Bruno Vilas Boas Dias, Jhenifer Luana dos Santos Camara, Bruno Oliveira Prado, Jean Jhonys Beraldes Cesar","doi":"10.4172/2167-0846.1000312","DOIUrl":"https://doi.org/10.4172/2167-0846.1000312","url":null,"abstract":"Objective: The objective of this study was to identify the view of nurses in the application of the pain scale in patients hospitalized in intensive care and medical clinic. Method: An exploratory-descriptive study was conducted with a qualitative approach in a private hospital in the interior of the State of Sao Paulo. The sample consisted of 20 nurses who answered 2 identical questionnaires, one demographic member with thirteen questions and the other with a dissertative question regarding the research objective. Results: Twenty nurses were interviewed, where 10 (50%) applied the scale at the time of patient admission, 4 (20%) applied the numerical scale more easily, while another 4 (20%) reported that they did not apply any pain scale. Among these, 20 (100%) consider the scale useful, 17 (85%) do not find difficulties in the application and 14 (70%) do not apply the scale in sedated patients. All of them recognized the importance of the scale and know pain as the 5th vital sign and it was clear that with the application of the scale it is possible to offer more comfort, evaluating the effectiveness of the medication and aiding in the clinical reasoning. Conclusion: All nurses consider it useful to use the pain scale, but lack of an institutional protocol often fails to apply the scale at important moments of patient admission.","PeriodicalId":16641,"journal":{"name":"Journal of Pain and Relief","volume":"187 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89007505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0