Journal of Orthopaedic Surgery最新文献

{"title":"Evolving organisational models in urban orthopaedic practice in India: A structured narrative review.","authors":"Raghu Yelavarthi, Ravi Chandra Vattipalli","doi":"10.1177/10225536261476473","DOIUrl":"https://doi.org/10.1177/10225536261476473","url":null,"abstract":"<p><p>Urban orthopaedic practice in India is undergoing profound organisational change driven by population ageing, an increasing burden of musculoskeletal disease, expanding subspecialisation, technological advances, and growing regulatory and quality-reporting requirements. These developments have renewed interest in organisational models capable of supporting coordinated, high-quality musculoskeletal care while maintaining clinical efficiency and professional sustainability. This structured narrative review evaluates contemporary organisational models of orthopaedic practice, with particular emphasis on structured group practice, within the Indian healthcare context. A structured narrative review was undertaken using PubMed as the primary database, supplemented by targeted Google Scholar searches and manual reference screening. Forty-five publications meeting predefined eligibility criteria were included in the final narrative synthesis. Evidence relating to orthopaedic practice organisation, subspecialisation, volume-outcome relationships, multidisciplinary care, clinical governance, registry participation, workforce wellbeing, health-system organisation, and practice sustainability was synthesised. The available literature suggests that structured group practice may facilitate subspecialty-focused care, multidisciplinary collaboration, standardisation of perioperative pathways, registry participation, continuous quality improvement, and equitable workload distribution. However, direct comparative evidence demonstrating superiority over well-organised solo or small-group practice remains limited, particularly in India. Many reported advantages appear to arise from effective evidence-based organisational processes rather than organisational size alone. The available evidence suggests that organisational models capable of supporting multidisciplinary care, clinical governance, and evidence-based organisational processes are increasingly important for contemporary orthopaedic practice. Structured group practice represents one context-dependent organisational approach that may be particularly relevant to urban India. The review identifies important evidence gaps, particularly the lack of comparative Indian studies, and highlights priorities for future research.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"34 2","pages":"10225536261476473"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148678936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Open resection versus arthroscopic resection for wrist ganglion cysts: A systematic review and meta-analysis.","authors":"Hyun-Gyu Seok, Jeong-Jin Park, Sam-Guk Park","doi":"10.1177/10225536261451304","DOIUrl":"10.1177/10225536261451304","url":null,"abstract":"<p><p>This study aimed to review the postoperative outcomes of surgical treatment options for wrist ganglion cysts and perform a meta-analysis comparing the 2 most common techniques: open and arthroscopic resection. We searched PubMed, Embase, Web of Science, and Cochrane Library databases for articles that compared the clinical outcomes of patients who underwent arthroscopic or open resection of the wrist ganglion. After screening, we identified two randomized controlled trials and four retrospective comparative studies. Recurrence rates, complications, functional scores, pain, operative time, and postoperative satisfaction were analyzed. A total of 6 studies met inclusion criteria for data extraction and qualitative synthesis. The two groups had no significant differences in the recurrence rate, postoperative pain, patient satisfaction, and clinical scores. The arthroscopic group had better results than the open group in terms of time to return to work. However, the arthroscopic group had a longer operation time than the open group.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"34 2","pages":"10225536261451304"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147982175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical applications of periarticular cocktail drug injection for unicompartmental knee arthroplasty: A narrative review.","authors":"Yuanhao Lv, Wanshun Liu, Jun Chen, Yu Huang, Xu Zhu, Qingde Wa","doi":"10.1177/10225536261451053","DOIUrl":"https://doi.org/10.1177/10225536261451053","url":null,"abstract":"<p><p>BackgroundPostoperative pain management following unicompartmental knee arthroplasty (UKA) remains a major challenge during the perioperative period. Local infiltration analgesia (LIA) using multimodal cocktail drugs injections has become an effective approach for perioperative pain control in UKA. However, most existing studies have focused on the use of cocktail drugs in total knee arthroplasty (TKA), whereas differences in their intraoperative application between UKA and TKA have rarely been reported.MethodsThis narrative review synthesizes literature identified from three databases. A comprehensive review of recent literature was conducted to summarize the different categories of cocktail drugs, their applications, efficacy, and evolving roles in UKA, and to compare their use with that in TKA.ResultsLocal injection of cocktail drugs, as an essential component of multimodal analgesia, has been widely applied during UKA. The cocktail drug approach provides synergistic advantages by combining multiple agents, resulting in enhanced analgesic and anti-inflammatory effects, prolonged duration of pain relief, and hemostatic benefits. At present, the primary method of administration involves intraoperative periarticular local infiltration. In most patients, postoperative pain scores and analgesic requirements during the early postoperative period, particularly within the 1-2 days after surgery, are lower after UKA than after TKA. Therefore, the formulations and dosages of cocktail drugs used in the two operations are not entirely identical.ConclusionsCocktail drug therapy is characterized by a simple administration procedure. Current evidence indicates that, for selected UKA patients, periarticular cocktail drugs injections can facilitate postoperative pain control and early functional recovery. Given the significant differences in surgical trauma, pain intensity, and tissue exposure between UKA and TKA, the direct application of TKA formulations to UKA should be approached with caution. However, UKA-specific studies remain limited, and further research is warranted to refine these protocols.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"34 2","pages":"10225536261451053"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148421737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of diagnostic efficacy and fracture healing predictive value of miR-550a-3p in patients with osteoporotic fractures.","authors":"Binbin Fan, Yiwei Li, Haitao Xu, Huaiwei Zhuang","doi":"10.1177/10225536261441917","DOIUrl":"10.1177/10225536261441917","url":null,"abstract":"<p><p>PurposeTo investigate the level of miR-550a-3p in patients with osteoporosis (OP), osteoporotic fractures (OPF), and healthy controls, and diagnostic value for OP, OPF, and fracture healing.Methods246 OP patients (120 OP, 126 OPF) and 113 healthy controls were enrolled. Serum miR-550a-3p levels were detected by reverse transcription-quantitative polymerase chain reaction (RT-qPCR). Pearson analysis assessed correlations with T-score, 25-(OH) Vitamin D, receptor activator of nuclear factor-κB ligand (RANKL), and osteoprotegerin (OPG). OPF patients were followed for 6 months (normal/delayed healing groups). Receiver operating characteristic (ROC) curves and logistic regression analyzed diagnostic value.ResultsmiR-550a-3p expression was significantly lower in OP and OPF groups than in controls, with the lowest level in OPF patients. It effectively distinguished OP from controls (AUC = 0.899) and OPF from OP (AUC = 0.911). miR-550a-3p was positively correlated with T-score, 25-(OH) Vitamin D, and OPG, and negatively correlated with RANKL. In OPF patients, miR-550a-3p was lower in the delayed healing (DH) group (AUC = 0.851) and identified as an independent factor for delayed healing.ConclusionmiR-550a-3p exhibits potential as a biomarker for diagnosing OP and OPF, and for predicting fracture healing outcomes in OPF patients, providing a novel tool for clinical management of osteoporotic fractures.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"34 2","pages":"10225536261441917"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148447596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The 100 most-cited articles on lumbar disc herniation: A bibliometric and network analysis.","authors":"Turgut Emre Erdem, Dilek Yapar, Tolga Sezer, Ahmet Serhat Aydın, Muhammed Yıldız, Volkan Büyükarslan, Selçuk Yılmaz","doi":"10.1177/10225536261472159","DOIUrl":"https://doi.org/10.1177/10225536261472159","url":null,"abstract":"<p><p>BackgroundLumbar disc herniation (LDH) generates a large and continuously expanding body of literature. Citation analysis identifies the publications that have most influenced a field, yet no bibliometric study has specifically examined the most-cited articles devoted to LDH as a clinical entity. The aim of this study was to identify and characterize the 100 most-cited articles on lumbar disc herniation.MethodsThe Web of Science Core Collection was searched on a single day using a title-field query combining recognized terms for lumbar disc herniation, restricted to articles and reviews published between 1980 and 2025. The ranked list was screened by one reviewer and independently verified by a second. For each article, the citation count, citation density, publication year, journal, country of origin, document type, authorship, study design, and subject focus were extracted and analyzed descriptively.ResultsThe 100 most-cited articles accumulated 17,179 citations (mean, 171.8; median, 126.5), with individual counts ranging from 91 to 879. They were published between 1980 and 2023, peaking in the 2000s (42 articles). The most-cited article was the randomized Spine Patient Outcomes Research Trial (879 citations), followed by Weber's 10-year controlled prospective study (807 citations). The articles appeared in 41 journals, with <i>Spine</i> dominant (40 articles), followed by European Spine Journal (6) and the Journal of Bone and Joint Surgery-American Volume (5). They originated from 21 countries; the United States led with 28 articles, but the three East Asian countries together contributed 32, collectively exceeding the United States. Original articles comprised 84 of the list and reviews 16. Treatment-oriented studies-surgical technique and outcome together with non-operative and interventional management-predominated.ConclusionsThe literature is dominated by treatment-focused research concentrated in a small number of specialty spine journals and-unlike comparable analyses of other spinal disorders-reflects a notably strong East Asian contribution alongside continued United States leadership.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"34 2","pages":"10225536261472159"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148812209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Workers' compensation status is associated with increased complications following distal radius fracture open reduction and internal fixation.","authors":"Sai Prasada Rao K Manikonda, Kaleb J Patterson, Joshua M Varghese, Sameer R Khawaja, Jad Lawand, Shragvi Balaji, Adil S Ahmed","doi":"10.1177/10225536261467667","DOIUrl":"https://doi.org/10.1177/10225536261467667","url":null,"abstract":"<p><p>BackgroundWhile workers' compensation (WC) patients often experience worse orthopedic outcomes, complication patterns following distal radius fracture (DRF) open reduction and internal fixation (ORIF) remain poorly defined. Prior DRF-specific studies include only small, regional cohorts. This study leverages Epic Cosmos to conduct the first nationwide analysis comparing complications between WC and non-WC populations.MethodsThis retrospective study queried the Epic Cosmos database for DRF ORIF procedures (2017-2024). WC patients (N = 4,101) were matched 1:5 with non-WC patients (N = 20,505) based on demographic and comorbidity characteristics. Patients required ≥6-month follow-up (mean 48.2 ± 28.6 and 48.9 ± 27.3 months for WC and non-WC patients, respectively). A subgroup analysis excluding patients with prior tendon injuries evaluated if WC status independently contributed to complication risk.ResultsWC patients had higher odds of complex regional pain syndrome (CRPS) (1.6% vs. 0.8%; OR 2.17, 95% CI [1.60, 2.91], <b>p < 0.001</b>), subsequent hardware removal (14.7% vs. 10.4%; OR 1.48, 95% CI [1.34, 1.63], <b>p < 0.001</b>), and postoperative stiffness (21.1% vs. 19.0%; OR 1.14, 95% CI [1.04, 1.23], <b>p = 0.003</b>), and lower odds of skin infection (2.9% vs. 4.0%; OR 0.73, 95% CI [0.59, 0.88], <b>p = 0.001</b>); all four associations remained significant after Bonferroni correction. No differences existed for venous thromboembolism, myocardial infarction, pulmonary embolism, or mechanical complication. Excluding prior tendon injury, CRPS remained significantly elevated in WC patients (OR 2.62, 95% CI [1.92, 3.57], <b>p < 0.001</b>).ConclusionsWC status is associated with higher risks of CRPS, subsequent hardware removal, and stiffness. Notably, CRPS risk remains elevated even after controlling for prior tendon injuries. As the largest WC-specific complication analysis for DRF ORIF to date, this exploratory study suggests that payer status may be a clinically meaningful correlate of postoperative morbidity. Future prospective studies are needed to confirm these associations.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"34 2","pages":"10225536261467667"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148404883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of core muscle strength and endurance with chronic ankle instability- A cross-sectional study.","authors":"Srijanya Rajesh, Ashish John Prabhakar, Charu Eapen, Vijayakumar Palaniswamy, Abraham M Joshua, Molly Cynthia D'Souza, Vivekbhai Dineshbhai Patel","doi":"10.1177/10225536261440986","DOIUrl":"10.1177/10225536261440986","url":null,"abstract":"<p><p>PurposeChronic Ankle Instability (CAI) often leads to debilitating, long-term consequences, and deficits in core muscle strength and endurance may contribute to the persistence of CAI. The current study aims to investigate the association between core strength and endurance with CAI.MethodsA total of 128 participants were enrolled, including 64 participants with CAI and 64 participants without instability. Ankle instability was evaluated using the Cumberland Ankle Instability Tool (CAIT). Core strength was assessed using a pressure biofeedback device, and endurance was assessed using the McGill Trunk Endurance Battery. Between group comparisons were conducted using the Mann-Whitney U test. Pearson correlation and multiple linear regression analyses were performed to identify key predictors of CAIT, including the interaction effects.ResultsThe CAI group revealed significantly lower endurance in trunk flexors (<i>p</i> = 0.003, r = 0.31) and extensors (<i>p</i> = 0.011, r = 0.26). No significant difference was observed in core strength (<i>p</i> = 0.954). CAIT scores were significantly associated with left lateral flexor endurance (r = 0.28, <i>p</i> = 0.012). The regression model indicated that left lateral flexor endurance showed a trend towards significance (β = 0.074, <i>p</i> = 0.055), suggesting a potential association rather than a definitive predictive role. An interaction effect (<i>p</i> = 0.054) suggested that this relationship may differ by group.ConclusionLateral trunk endurance may play a role in functional ankle stability. These findings suggest that incorporating core endurance training into rehabilitation programs for CAI may be beneficial; however, further research is required to confirm these relationships.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"34 2","pages":"10225536261440986"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148218081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reconstruction of plantar degloving injuries using a prefabricated anterolateral thigh plantar glabrous skin flap.","authors":"Xingfei Zhang, Jiandong Zhou, Yuxuan Zhang, Wencheng Wang, Jian Tian, Xueming Chen, Yajun Xu","doi":"10.1177/10225536261456783","DOIUrl":"10.1177/10225536261456783","url":null,"abstract":"<p><p>ObjectivesTo evaluate the clinical efficacy of reconstruction of plantar degloving injuries using a prefabricated anterolateral thigh plantar glabrous skin flap (PALT-PGSF).MethodsTwelve patients, aged 22-56 years, with plantar degloving injuries were treated between July 2016 and December 2022. These defects are typically caused by traffic or machinery trauma. The avulsed plantar skin surfaces are intact, but revascularization are deemed unsuitable. The free tissue flaps transposed to reconstruct the defects were PALT-PGSFs. The flap size varied in width (6-13) cm and length (8-26 cm). The time from admission to reconstruction was 14-32 days (average, 23.1 days). The follow-up period ranged from 12 to 87 months (mean, 36.6 months).ResultsEight cases were closed primarily and the other four were covered with skin grafts. All flaps survived; however, one case underwent an exploration procedure twice due to venous and arterial thrombosis. In two cases, ulcers occurred in the nonfabricated area of the flap, which was excised and replaced by PALT-PGSF area during the internal fixation removal and defatting procedure. In the other two cases, ulcers appeared on the front or outside of the feet. All the cases gained protective sensation on the weight-bearing portion of the heel. Patients can perform daily walking normally, and younger patients can even complete running and jumping exercises.ConclusionWe advocate the use of the ALT-PGSF for the reconstruction of plantar degloving injuries.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"34 2","pages":"10225536261456783"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148055040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-world comparative effectiveness of denosumab versus zoledronic acid on bone mineral density changes in postmenopausal osteoporosis: An IPTW cohort study.","authors":"Qinglong Li, Huagang Shi, Wei Hou, Tao Gu, Simao Song","doi":"10.1177/10225536261470877","DOIUrl":"https://doi.org/10.1177/10225536261470877","url":null,"abstract":"<p><p>BackgroundTo compare the real-world effectiveness and safety of denosumab versus zoledronic acid in postmenopausal osteoporosis (PMO) and characterize baseline fracture risk profiles.MethodsThis retrospective cohort study included 250 PMO patients treated with denosumab (n = 148) or zoledronic acid (n = 102). Inverse probability of treatment weighting (IPTW) was applied to balance baseline covariates. The primary endpoint was 12-month change in lumbar spine bone mineral density (BMD). Fracture risk status was descriptively analyzed.ResultsThe cohort was predominantly high-risk (98.4%). IPTW achieved adequate covariate balance. At 12 months, denosumab showed greater increases in lumbar spine BMD than zoledronic acid (6.09% vs. 4.82%; difference 1.27%, 95% CI: 0.474-2.067; P = 0.002), with consistent findings at the hip. Most adverse events were comparable between groups; however, acute phase reaction occurred significantly less frequently with denosumab, while no differences were observed in hypocalcemia or renal events.ConclusionDenosumab was associated with greater BMD gains than zoledronic acid over 12 months, with broadly comparable safety in a real-world PMO population. These findings are limited to short-term BMD outcomes.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"34 2","pages":"10225536261470877"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148471398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cryotherapy modulates femoral nerve afferent signals after simulated anterior cruciate ligament reconstruction in a rabbit model.","authors":"Joe M Hart, Kimberly A Pritchard, Bradley J Lauck, MaCalus V Hogan, Susan A Saliba","doi":"10.1177/10225536261474688","DOIUrl":"https://doi.org/10.1177/10225536261474688","url":null,"abstract":"<p><p>BackgroundAberrant sensory information arising from damaged knee joint tissues is an underlying cause of post-traumatic quadriceps arthrogenic muscle inhibition which commonly follows joint injury. This study aimed to determine if aberrant sensory information from damaged knee joints could be modulated using cryotherapy.MethodsComposite femoral nerve sensory signal was measured during passive knee extension in 16 rabbits. Ten rabbits underwent unilateral leg surgery to simulate the joint damage created during anterior cruciate ligament reconstruction, and 6 rabbits were healthy controls receiving no intervention. Focal knee joint cryotherapy treatment was administered for 15 minutes in all 12 control and 10 surgical limbs. Nerve measurements were repeated after cryotherapy. Side-to-side ratios (surgical side vs. contralateral healthy side) for peak filtered and integrated whole nerve composite signal were compared before and following cryotherapy treatment.ResultsPeak femoral nerve signal was significantly higher in the surgical leg (4.68±1.95) compared to the contralateral leg (3.25±2.04) in rabbits who underwent unilateral surgery (p=0.049). There was no difference in side-to-side limb comparison in control animals (p=0.337). The peak femoral nerve signal in the surgically involved rabbits was significantly reduced following cryotherapy in the surgical leg (p=0.005).ConclusionComposite femoral nerve afferent signal is greater in injured knees than in healthy knees relative to the contralateral side. Cryotherapy resulted in a significantly downregulated sensory response from the surgical limb.</p>","PeriodicalId":16608,"journal":{"name":"Journal of Orthopaedic Surgery","volume":"34 2","pages":"10225536261474688"},"PeriodicalIF":1.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148630619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}