Journal of opioid management最新文献_第7页

Examining the relationship between head trauma and opioid use disorder: A systematic review 研究头部创伤与阿片类药物使用障碍之间的关系：系统回顾

Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0846

Ali Abid, Mariam Paracha, Iva Çepele, Awais Paracha, Joseph Rueve, Akbar Fidahussain, Humza Rehman, Mckimmon Engelhardt, Noor Alyasiry, Zohair Siddiqui, Satvik Vasireddy, Bishal Kadariya, Nikitha B. Rao, Rohan Das, Wilson Rodriguez, Dixie Meyer

{"title":"Examining the relationship between head trauma and opioid use disorder: A systematic review","authors":"Ali Abid, Mariam Paracha, Iva Çepele, Awais Paracha, Joseph Rueve, Akbar Fidahussain, Humza Rehman, Mckimmon Engelhardt, Noor Alyasiry, Zohair Siddiqui, Satvik Vasireddy, Bishal Kadariya, Nikitha B. Rao, Rohan Das, Wilson Rodriguez, Dixie Meyer","doi":"10.5055/jom.0846","DOIUrl":"https://doi.org/10.5055/jom.0846","url":null,"abstract":"Objective: To examine recent literature and determine common clinical risk factors between antecedent traumatic brain injury (TBI) and the following development of opioid misuse and provide a framework for clinical identification of at-risk subjects and evaluate potential treatment implications within this association. \u0000Design: A comprehensive systematic literature search of PubMed was conducted for articles between 2000 and December 2022. Studies were included if the human participant had any head trauma exposure and any chronic opioid use or dependence. After eligibility criteria were applied, 16 studies were assessed for thematic trends. \u0000Results: Opioid use disorder (OUD) risks are heightened in cohorts with head trauma exposed to opioids while in the hospital, specifically with tramadol and oxycodone. Chronic pain was the most common predictor of long-term OUD, and continuous somatic symptoms associated with the TBI can lead to long-term opioid usage. Individuals who present with coexisting psychiatric conditions pose significantly more risk associated with a higher risk of long-term opioid use. \u0000Conclusion: Findings indicate that therapists and clinicians must consider a risk profile for persons with TBI and follow an integrated care approach to account for mental health, prior substance misuse, presenting somatic symptoms, and current medication regimen during evaluation.","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":" 50","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139792984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Opioid stewardship program implementation in rural and critical access hospitals in Arizona 在亚利桑那州的农村医院和关键通道医院实施阿片类药物管理计划

Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0842

Benjamin R. Brady, Bianca SantaMaria, Kathryn Tucker Ortiz y Pino, Bridget S. Murphy

{"title":"Opioid stewardship program implementation in rural and critical access hospitals in Arizona","authors":"Benjamin R. Brady, Bianca SantaMaria, Kathryn Tucker Ortiz y Pino, Bridget S. Murphy","doi":"10.5055/jom.0842","DOIUrl":"https://doi.org/10.5055/jom.0842","url":null,"abstract":"Objective: The objective of this study is to examine rural hospitals' status in implementing opioid stewardship program (OSP) elements and assess differences in implementation in emergency department (ED) and acute inpatient departments. \u0000Design: Health administrator survey to identify the number and type of OSP elements that each hospital has implemented. \u0000Setting: Arizona critical access hospitals (CAHs). \u0000Participants: ED and acute inpatient department heads at 17 Arizona CAHs (total of 34 assessments). \u0000Main outcome measures: Implementation of 11 OSP elements, by department (ED vs inpatient) and prevention orientation (primary vs tertiary). \u0000Results: The percentage of implemented elements ranged from 35 to 94 percent in EDs and 24 to 88 percent in acute care departments. Reviewing the prescription drug monitoring program database and offering alternatives to opioids were the most frequently implemented. Assessing opioid use disorder (OUD) and prescribing naloxone were among the least. The number of implemented elements tended to be uniform across departments. We found that CAHs implemented, on average, 67 percent of elements that prevent unnecessary opioid use and 54 percent of elements that treat OUD. \u0000Conclusions: Some OSP elements were in place in nearly every Arizona CAH, while others were present in only a quarter or a third of hospitals. To improve, more attention is needed to define and standardize OSPs. Equal priority should be given to preventing unnecessary opioid initiation and treating opioid misuse or OUD, as well as quality control strategies that provide an opportunity for continuous improvement. \u0000 ","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":" 67","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139793015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Short-term healthcare resource utilization associated with receipt of CDC-informed opioid thresholds among commercially insured new chronic opioid users 商业保险新慢性阿片类药物使用者接受疾病预防控制中心提供的阿片类药物阈值后的短期医疗资源利用情况

Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0848

Martin J. Calabrese, F. Shaya, Francis Palumbo, M. Mcpherson, Ester Villalonga-Olives, Z. Zafari, Ryan Mutter

{"title":"Short-term healthcare resource utilization associated with receipt of CDC-informed opioid thresholds among commercially insured new chronic opioid users","authors":"Martin J. Calabrese, F. Shaya, Francis Palumbo, M. Mcpherson, Ester Villalonga-Olives, Z. Zafari, Ryan Mutter","doi":"10.5055/jom.0848","DOIUrl":"https://doi.org/10.5055/jom.0848","url":null,"abstract":"Objective: To evaluate the impact of recent changes to the Centers for Disease Control and Prevention (CDC) morphine milligram equivalent (MME)/day threshold recommendations on healthcare utilization. \u0000Design: A retrospective cohort study of new chronic opioid users (NCOUs). \u0000Setting: Commercially insured plans across the United States using IQVIA PharMetrics® Plus for Academics database with new use between January 2014 and March 2015. \u0000Patients: NCOUs with ≥60-day coverage of opioids within a 90-day period with ≥30-day opioid-free period prior to the date of the first qualifying opioid prescription. \u0000Interventions: NCOU categorized by the CDC three-tiered risk-based average MME/day thresholds: low (>0 to <50), medium (≥50 to <90), and high (≥90). \u0000Main outcome measures: Multivariable logistic regression was used to calculate adjusted odds of incurring an acute care encounter (ACE) (all-cause and opioid related) between the thresholds (adjusted odds, 95 percent confidence interval). \u0000Results: In adjusted analyses, when compared to low threshold, there was no difference in the odds of all-cause ACE across the medium (1.01, 0.94-1.28) and high (1.01, 0.84-1.22) thresholds. When compared to low threshold, a statistically insignificant increase was observed when evaluating opioid-related ACE among medium (1.86, 0.86-4.02) and high (1.51, 0.65-3.52) thresholds. \u0000Conclusions: There was no difference in odds of an all-cause or opioid-related ACE associated with the thresholds. Early-intervention programs and policies exploring reduction of MME/day among NCOUs may not result in short-term reduction in all-cause or opioid-related ACEs. Further assessment of potential long-term reduction in ACEs among this cohort may be insightful. \u0000 ","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":" 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139793444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Opioid stewardship program implementation in rural and critical access hospitals in Arizona 在亚利桑那州的农村医院和关键通道医院实施阿片类药物管理计划

Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0842

Benjamin R. Brady, Bianca SantaMaria, Kathryn Tucker Ortiz y Pino, Bridget S. Murphy

{"title":"Opioid stewardship program implementation in rural and critical access hospitals in Arizona","authors":"Benjamin R. Brady, Bianca SantaMaria, Kathryn Tucker Ortiz y Pino, Bridget S. Murphy","doi":"10.5055/jom.0842","DOIUrl":"https://doi.org/10.5055/jom.0842","url":null,"abstract":"Objective: The objective of this study is to examine rural hospitals' status in implementing opioid stewardship program (OSP) elements and assess differences in implementation in emergency department (ED) and acute inpatient departments. \u0000Design: Health administrator survey to identify the number and type of OSP elements that each hospital has implemented. \u0000Setting: Arizona critical access hospitals (CAHs). \u0000Participants: ED and acute inpatient department heads at 17 Arizona CAHs (total of 34 assessments). \u0000Main outcome measures: Implementation of 11 OSP elements, by department (ED vs inpatient) and prevention orientation (primary vs tertiary). \u0000Results: The percentage of implemented elements ranged from 35 to 94 percent in EDs and 24 to 88 percent in acute care departments. Reviewing the prescription drug monitoring program database and offering alternatives to opioids were the most frequently implemented. Assessing opioid use disorder (OUD) and prescribing naloxone were among the least. The number of implemented elements tended to be uniform across departments. We found that CAHs implemented, on average, 67 percent of elements that prevent unnecessary opioid use and 54 percent of elements that treat OUD. \u0000Conclusions: Some OSP elements were in place in nearly every Arizona CAH, while others were present in only a quarter or a third of hospitals. To improve, more attention is needed to define and standardize OSPs. Equal priority should be given to preventing unnecessary opioid initiation and treating opioid misuse or OUD, as well as quality control strategies that provide an opportunity for continuous improvement. \u0000 ","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139852759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic opioid pain treatment converted to buprenorphine: A case series using a 3-step low-dose incremental dosing guideline 改用丁丙诺啡治疗慢性阿片类疼痛：使用三步低剂量递增剂量指南的病例系列

Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0822

Gregory Acampora, Yi Zhang

引用次数: 0

Role of opioid use in gastrointestinal obstruction and perforation: A retrospective review 阿片类药物在胃肠道梗阻和穿孔中的作用：回顾性研究

Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0850

Divya Bishnoi, Priyanka Sharma, A. K. Rathi

{"title":"Role of opioid use in gastrointestinal obstruction and perforation: A retrospective review","authors":"Divya Bishnoi, Priyanka Sharma, A. K. Rathi","doi":"10.5055/jom.0850","DOIUrl":"https://doi.org/10.5055/jom.0850","url":null,"abstract":"Introduction: Pain is one of the most common complaints that brings a patient to a hospital. For this, usually, the patient might have already consumed various types of pain killer combinations, either prescribed or over-the-counter. In some of these cases, a patient consumes these medicines unmonitored for a long time and then comes with complications, among which gastrointestinal tract obstruction and perforation are the most life threatening. \u0000Materials and methods: Case files from the Department of Surgery were retrieved and studied. Patients were contacted telephonically for details of drug abuse history. These were then further studied in detail. \u0000Results: Forty-eight (68 percent) patients out of a total of 78 had a history of drug abuse. The most commonly abused pain killer was a combination of anti-inflammatory and other salts, which was found in 22 (46 percent) patients, followed by tramadol, NSAIDs, opium, and alcohol (23, 17, 10, and 4 percent, respectively). These groups were comparable in socio-demographic details except in the mean age, occupation, and gender distribution, and the difference was significant (p < 0.01). The most common cause for starting to use any of the above-mentioned pain killer was persistent pain. The most common site of obstruction in drug abusers was the stomach (60 percent), followed by the small intestine (38 percent) and the large intestine (2 percent). \u0000Limitations: (1) This is an observational retrospective record review. (2) Records were studied in hospital settings, so results should be generalized cautiously. (3) Risk of recall bias is present. \u0000Conclusion: Pain killers should always be prescribed with caution and for a short duration. Alternative options for pain relief should be made available, and doctors should be trained. Drug abusers tend to have a gastrointestinal complication at an early age, which means they are prone to further complications and recurrence if the problem is not addressed on time.","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":"228 1-2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139852424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tianeptine as an opiate replacement in a patient on methadone treatment: A case report 将替奈普汀作为美沙酮治疗患者的鸦片制剂替代品：病例报告

Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0851

Vivek Velagapudi, Jordan Calabrese, Roopa Sethi

引用次数: 0

Patient genetic heterogeneities acting as indicators of post-operative pain and opioid requirement in orthopedic surgery: A systematic review 作为骨科手术术后疼痛和阿片类药物需求指标的患者遗传异质性：系统综述

Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0809

Ahmad I Hasan, Adam Pearl, Mohammad Daher, Khaled J. Saleh

{"title":"Patient genetic heterogeneities acting as indicators of post-operative pain and opioid requirement in orthopedic surgery: A systematic review","authors":"Ahmad I Hasan, Adam Pearl, Mohammad Daher, Khaled J. Saleh","doi":"10.5055/jom.0809","DOIUrl":"https://doi.org/10.5055/jom.0809","url":null,"abstract":"Introduction: Orthopedic surgical procedures are expected to increase annually, making it imperative to understand the correlations between patient genetic makeup and post-operative pain levels. \u0000Methods: We performed a systematic literature review using PubMed and Cochrane databases in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A total of 299 articles were initially selected, 20 articles remained after title and abstract review, and nine articles were selected for inclusion upon full text review. \u0000Results: Genetic risk factors identified included the A allele of the 5HT2A gene single nucleotide polymorphism, the AA genotype of the ADRB2 gene, the CG genotype of the IL6 gene, the genotypes CT and TT of the NTRK1 gene, genotypes AA and GA of the OPRM gene, and the AA and GA genotypes of the COMT gene. Additional studies in the review discuss statistical significance of other variants of the COMT gene. \u0000Conclusion: There have been genetic association studies performed on the patient heterogeneity and its relationship on patient pain levels, but more data need to be collected to understand the clinical utility of stratifying patients based on genomic sequence.","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":" 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139790975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examining the relationship between head trauma and opioid use disorder: A systematic review 研究头部创伤与阿片类药物使用障碍之间的关系：系统回顾

Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0846

Ali Abid, Mariam Paracha, Iva Çepele, Awais Paracha, Joseph Rueve, Akbar Fidahussain, Humza Rehman, Mckimmon Engelhardt, Noor Alyasiry, Zohair Siddiqui, Satvik Vasireddy, Bishal Kadariya, Nikitha B. Rao, Rohan Das, Wilson Rodriguez, Dixie Meyer

{"title":"Examining the relationship between head trauma and opioid use disorder: A systematic review","authors":"Ali Abid, Mariam Paracha, Iva Çepele, Awais Paracha, Joseph Rueve, Akbar Fidahussain, Humza Rehman, Mckimmon Engelhardt, Noor Alyasiry, Zohair Siddiqui, Satvik Vasireddy, Bishal Kadariya, Nikitha B. Rao, Rohan Das, Wilson Rodriguez, Dixie Meyer","doi":"10.5055/jom.0846","DOIUrl":"https://doi.org/10.5055/jom.0846","url":null,"abstract":"Objective: To examine recent literature and determine common clinical risk factors between antecedent traumatic brain injury (TBI) and the following development of opioid misuse and provide a framework for clinical identification of at-risk subjects and evaluate potential treatment implications within this association. \u0000Design: A comprehensive systematic literature search of PubMed was conducted for articles between 2000 and December 2022. Studies were included if the human participant had any head trauma exposure and any chronic opioid use or dependence. After eligibility criteria were applied, 16 studies were assessed for thematic trends. \u0000Results: Opioid use disorder (OUD) risks are heightened in cohorts with head trauma exposed to opioids while in the hospital, specifically with tramadol and oxycodone. Chronic pain was the most common predictor of long-term OUD, and continuous somatic symptoms associated with the TBI can lead to long-term opioid usage. Individuals who present with coexisting psychiatric conditions pose significantly more risk associated with a higher risk of long-term opioid use. \u0000Conclusion: Findings indicate that therapists and clinicians must consider a risk profile for persons with TBI and follow an integrated care approach to account for mental health, prior substance misuse, presenting somatic symptoms, and current medication regimen during evaluation.","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":"128 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139852803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient genetic heterogeneities acting as indicators of post-operative pain and opioid requirement in orthopedic surgery: A systematic review 作为骨科手术术后疼痛和阿片类药物需求指标的患者遗传异质性：系统综述

Journal of opioid management Pub Date : 2024-02-08 DOI: 10.5055/jom.0809

Ahmad I Hasan, Adam Pearl, Mohammad Daher, Khaled J. Saleh

{"title":"Patient genetic heterogeneities acting as indicators of post-operative pain and opioid requirement in orthopedic surgery: A systematic review","authors":"Ahmad I Hasan, Adam Pearl, Mohammad Daher, Khaled J. Saleh","doi":"10.5055/jom.0809","DOIUrl":"https://doi.org/10.5055/jom.0809","url":null,"abstract":"Introduction: Orthopedic surgical procedures are expected to increase annually, making it imperative to understand the correlations between patient genetic makeup and post-operative pain levels. \u0000Methods: We performed a systematic literature review using PubMed and Cochrane databases in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A total of 299 articles were initially selected, 20 articles remained after title and abstract review, and nine articles were selected for inclusion upon full text review. \u0000Results: Genetic risk factors identified included the A allele of the 5HT2A gene single nucleotide polymorphism, the AA genotype of the ADRB2 gene, the CG genotype of the IL6 gene, the genotypes CT and TT of the NTRK1 gene, genotypes AA and GA of the OPRM gene, and the AA and GA genotypes of the COMT gene. Additional studies in the review discuss statistical significance of other variants of the COMT gene. \u0000Conclusion: There have been genetic association studies performed on the patient heterogeneity and its relationship on patient pain levels, but more data need to be collected to understand the clinical utility of stratifying patients based on genomic sequence.","PeriodicalId":16601,"journal":{"name":"Journal of opioid management","volume":"67 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139850785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0