Global Journal of Cancer Case Reports最新文献_第2页

Fluoroscopic Demonstration of Thoracic Tumor Immobilization with High Frequency Percussive Ventilation 高频冲击通气胸腔肿瘤固定的透视证明

Global Journal of Cancer Case Reports Pub Date : 1900-01-01 DOI: 10.47733/gjccr.2020.1207

I. M. Sala, B. Maurer, Cristian Solano, R. Levitin, T. M. Guerrero

{"title":"Fluoroscopic Demonstration of Thoracic Tumor Immobilization with High Frequency Percussive Ventilation","authors":"I. M. Sala, B. Maurer, Cristian Solano, R. Levitin, T. M. Guerrero","doi":"10.47733/gjccr.2020.1207","DOIUrl":"https://doi.org/10.47733/gjccr.2020.1207","url":null,"abstract":"Purpose: The purpose of this first-in-man study is to directly measure thoracic tumor immobilization by high frequency percussive ventilation (HFPV). Methods: In an IRB approved protocol (IRB # 2017-046) we screened patients with conspicuous lung tumors that exhibited motion >10 mm to undergo kV fluoroscopy with HFPV. Two sets of consecutive AP (anterior posterior) fluoroscopy frames were acquired during multiple breathing cycles for freeand HFPVbreathing. All images were acquired using our kV source/panel of the therapeutic linear accelerator. Percussions were delivered via the intrapulmonary percussive ventilation device (IPV-2C) and phasitron (Percussionaire Corp., Sagle, Idaho). The baseline settings for the IPV-2C (pressure, frequency, CPAP and inspiration time) were set during an initial training session, but minor adjustments were made prior to imaging at the direction and comfort of the patient. Results: Patient recruited was a 69 y.o. female with stage IB (cT2a, cN0, cM0) adenocarcinoma of the LLL with lepidic and acinar growth pattern. She experienced slight discomfort lying flat on the treatment table, however successfully completed HFPV. Peak-to-peak tumor motion during 4DCT sim was 11.0 mm, however patient had already received 4x 10Gy fractions of SBRT when enrolled in the study, and therefore peak-to-peak motion during free-breathing measured with fluoroscopy, at the time of the study, was 6.2 mm. Subsequently, peak-to-peak motion measured with fluoroscopy during HFPV was at 2.7 mm. This resulted in a 57 % tumor motion reduction. Conclusion: In this first-in-man study, we have shown that HFPV is a novel respiratory motion technique that can significantly reduce tumor motion.","PeriodicalId":165998,"journal":{"name":"Global Journal of Cancer Case Reports","volume":"151 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113986786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Role of Primary and Metastasis Directed Radiotherapy in Metastatic Nasopharyngeal Cancer 原发性和转移性放疗在转移性鼻咽癌中的作用

Global Journal of Cancer Case Reports Pub Date : 1900-01-01 DOI: 10.47733/gjccr.2021.2202

Ismail Ghorbel

引用次数: 0

A Prosthetically Driven Approach for Immediate Dental Implant Reconstruction of a Maxillary Free Fibula Flap with the Aid of Virtual Three-Dimensional Planning and Intra-Operative Navigation 虚拟三维规划及术中导航在上颌游离腓骨瓣即刻种植重建中的应用

Global Journal of Cancer Case Reports Pub Date : 1900-01-01 DOI: 10.47733/gjccr.2022.3102

Gwendolyn S. Reeve, J. Spector, D. Kutler, H. J. Hansen

{"title":"A Prosthetically Driven Approach for Immediate Dental Implant Reconstruction of a Maxillary Free Fibula Flap with the Aid of Virtual Three-Dimensional Planning and Intra-Operative Navigation","authors":"Gwendolyn S. Reeve, J. Spector, D. Kutler, H. J. Hansen","doi":"10.47733/gjccr.2022.3102","DOIUrl":"https://doi.org/10.47733/gjccr.2022.3102","url":null,"abstract":"Objective: To describe a prosthetically-driven reconstruction of an edentulous atrophic maxilla and mandible using 3D surgical planning and intra-operative navigation. Methods: A twenty-eight-year-old male presented for reconstruction with fixed dental prostheses after a gunshot wound caused severe atrophy of the jaws and nasal deformity. His dentition was non-salvageable with insufficient maxillary bone for dental implant placement. To restore his midfacial deformity, reestablish upper lip support, and provide adequate bone, his maxilla was reconstructed using a free fibula flap. Dental implant placement is dictated by the planned prosthetic tooth position, and therefore the design of the maxillary reconstruction considered the necessary prosthetic space and the location of the planned prosthetics via Virtual Surgical planning. Intra-operative navigation confirmed the correct placement of the flap using surgical probe guidance. Results: Using our precise and prosthetically driven method, we were able to place dental implants to support fixed dental prostheses and correct the skeletal deformity in a single surgery. Conclusion: Traditional dental prosthetic design principles were applied to optimize functional and esthetic outcomes in a complex case of simultaneous maxilla-mandibular reconstruction. The use of 3D surgical planning and intra-operative navigation allowed us to shorten the treatment time providing a predictable and accurate outcome.","PeriodicalId":165998,"journal":{"name":"Global Journal of Cancer Case Reports","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126205486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Primary Occult Breast Cancer in A Male Patient: A Case Report and Brief Overview of Literature 男性原发性隐匿性乳腺癌1例报告及文献综述

Global Journal of Cancer Case Reports Pub Date : 1900-01-01 DOI: 10.47733/gjccr.2020.2103

Luis E. Fregoso Arteaga, B. Z. Retes, Fatima Rincon Cabada, Michael P. White

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Molecular Basis of Synovial Sarcoma and the Rare Case of its Localization in Palatine Tonsil: A Review of the Literature 滑膜肉瘤的分子基础及其定位于腭扁桃体的罕见病例:文献综述

Global Journal of Cancer Case Reports Pub Date : 1900-01-01 DOI: 10.47733/gjccr.2021.2203

N. Chrysanthakopoulos, E. Vryzaki, K. Karkoulias

{"title":"Molecular Basis of Synovial Sarcoma and the Rare Case of its Localization in Palatine Tonsil: A Review of the Literature","authors":"N. Chrysanthakopoulos, E. Vryzaki, K. Karkoulias","doi":"10.47733/gjccr.2021.2203","DOIUrl":"https://doi.org/10.47733/gjccr.2021.2203","url":null,"abstract":"Synovial sarcomas (SS) are rare soft tissue malignant tumors that mainly arise from the lower extremities, especially the lower thigh-knee region. The literature has shown that this tumor may be observed in uncommon regions such as the abdominal wall and the head and neck region which are non-synovium-lined spaces. SS rarely occurs in the head and neck region, as only 3-10% of these neoplasms appear in this region. The parapharyngeal space is the most common location, whereas primary SS of the palatine tonsil is extremely rare as only a few cases of primary tonsillar SS have been described. It is considered as a high grade malignant tumor, however current investigation regarding its clinical and histopathological features revealed in all these cases a biphasic morphology. Molecular analyses detected a typical SYT gene t(X;18) (p11; q11) translocation and a representative SYT/SSX1fusion type. Immunohistochemical analysis recorded cytokeratin OSCAR, Bcl-2, EMA, vimentin, TLE1 and PGP 9.5, were diffusely positive. The aim of the current review was to present the molecular basis of SS and SS rare location in palatine tonsil.","PeriodicalId":165998,"journal":{"name":"Global Journal of Cancer Case Reports","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127176150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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