2018 3rd Biennial South African Biomedical Engineering Conference (SAIBMEC)最新文献

A study of short cessations and temporal dynamics of breathing in preterm infants 早产儿短时间停止呼吸和时间动力学的研究

2018 3rd Biennial South African Biomedical Engineering Conference (SAIBMEC) Pub Date : 2018-05-23 DOI: 10.1109/SAIBMEC.2018.8363174

M. Bester, D. van den Heever, Rohan Joshi, K. Dellimore

{"title":"A study of short cessations and temporal dynamics of breathing in preterm infants","authors":"M. Bester, D. van den Heever, Rohan Joshi, K. Dellimore","doi":"10.1109/SAIBMEC.2018.8363174","DOIUrl":"https://doi.org/10.1109/SAIBMEC.2018.8363174","url":null,"abstract":"The current clinical definition of Apnea of Prematurity (AOP) in infants is cessations of breathing exceeding 20 s, or at least 10 s accompanied by bradycardia under 100 beats per minute (bpm) or desaturation below 80%. AOP has a negative effect on infant health as it can increase the risk of hypoxemia, hypoglycaemia, neurological injury and sepsis. However, the detrimental effects of AOP are poorly understood, in large part because apneas are difficult to monitor owing to limitations in the current modalities for monitoring respiration. This study investigates the respiratory dynamics of preterm infants by implementing, with modifications, a pre-existing breathing cessation-detection algorithm. Unlike other studies, we also analyze short cessations in breathing (2–5 s), so as to better quantify respiratory dynamics, temporally track respiratory stability and to investigate whether short cessations in breathing are related to apnea. We found that isolated 2–5 s cessations have a significant impact on the total time of breathing cessation, increasing it from 3.0% to 4.3%. Furthermore, short cessations in breathing are positively correlated to apnea. Finally, there are multiple periodic increases in cessations of breathing within a day.","PeriodicalId":165912,"journal":{"name":"2018 3rd Biennial South African Biomedical Engineering Conference (SAIBMEC)","volume":"128 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128153404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Construction and validation of image-based statistical shape and intensity models of bone 基于图像的骨形状和强度统计模型的构建和验证

2018 3rd Biennial South African Biomedical Engineering Conference (SAIBMEC) Pub Date : 2018-04-04 DOI: 10.1109/SAIBMEC.2018.8363176

C. Reyneke, Xolisile O. Thusini, T. Douglas, T. Vetter, Tinashe Ernest Mutsvangwa

{"title":"Construction and validation of image-based statistical shape and intensity models of bone","authors":"C. Reyneke, Xolisile O. Thusini, T. Douglas, T. Vetter, Tinashe Ernest Mutsvangwa","doi":"10.1109/SAIBMEC.2018.8363176","DOIUrl":"https://doi.org/10.1109/SAIBMEC.2018.8363176","url":null,"abstract":"Three-dimensional models of bone structures, inferred from 3D and 2D imaging modalities, provide a number of uses for medical professionals. Such models are typically constructed using mesh-based approaches and some form of principal component analysis (PCA). Image-based approaches are understood to have a number of advantages over mesh-based ones, such as the absence of intrinsic segmentation as well as a better reproduction fidelity. Furthermore, Gaussian process morphable models have recently been shown to offer added benefits to the traditional PCA-based approach, such as the ability to easily incorporate prior knowledge into the model, and a resolution that can be made application-specific. We demonstrate how to build an image-based statistical shape and intensity model (SSIM) using Gaussian process morphable models and validate the quality of the model using common mesh model metrics that we adapt to the image-based paradigm. Our results show that the model can generate valid novel femur examples and can be registered to unseen femur examples with average root mean square error and average mutual information score of 0.172 and 0.644, respectively. However, only twenty binary training examples are used, each limited to contain approximately 65000 voxels. Future work will aim at extending the image-based SSIM to include the full range of CT intensity values; larger CT volumes and improve on the model building time.","PeriodicalId":165912,"journal":{"name":"2018 3rd Biennial South African Biomedical Engineering Conference (SAIBMEC)","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116870032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Evaluating the impact of air compliance chamber volumes on valve performance for three different heart valves 评估空气顺应室容积对三种不同心脏瓣膜性能的影响

2018 3rd Biennial South African Biomedical Engineering Conference (SAIBMEC) Pub Date : 2018-04-04 DOI: 10.1109/SAIBMEC.2018.8363178

Kyle Davis, J. Muller, C. Meyer, F. Smit

引用次数: 2

Modified desktop inkjet printer as low-cost material deposition device 改进台式喷墨打印机作为低成本材料沉积设备

2018 3rd Biennial South African Biomedical Engineering Conference (SAIBMEC) Pub Date : 2018-04-04 DOI: 10.1109/SAIBMEC.2018.8363183

J. D. Retief, P. Fourie, W. J. Perold

引用次数: 5

Introducing and embedding innovation practices in a UK medical engineering degree course 在英国医学工程学位课程中引入和嵌入创新实践

2018 3rd Biennial South African Biomedical Engineering Conference (SAIBMEC) Pub Date : 2018-04-04 DOI: 10.1109/SAIBMEC.2018.8363182

M. Raxworthy

引用次数: 0

Modelling dynamic response of physical systems in Simulink 物理系统在Simulink中的动态响应建模

2018 3rd Biennial South African Biomedical Engineering Conference (SAIBMEC) Pub Date : 2018-04-04 DOI: 10.1109/SAIBMEC.2018.8363187

K. T. Smith, D. Rubin, M. Turner

引用次数: 1

Towards a framework for technology platform design, development and implementation in South African health: Preliminary validation 建立南非卫生领域技术平台设计、开发和实施框架:初步验证

2018 3rd Biennial South African Biomedical Engineering Conference (SAIBMEC) Pub Date : 2018-04-01 DOI: 10.1109/SAIBMEC.2018.8363194

H. Herman, S. Grobbelaar, C. Pistorius

引用次数: 3

Developing a decision support system for medical trial recruitment management and planning 开发医学试验招聘管理与规划决策支持系统

2018 3rd Biennial South African Biomedical Engineering Conference (SAIBMEC) Pub Date : 2018-04-01 DOI: 10.1109/SAIBMEC.2018.8363185

Natalie de Bruyn, S. Grobbelaar

{"title":"Developing a decision support system for medical trial recruitment management and planning","authors":"Natalie de Bruyn, S. Grobbelaar","doi":"10.1109/SAIBMEC.2018.8363185","DOIUrl":"https://doi.org/10.1109/SAIBMEC.2018.8363185","url":null,"abstract":"Randomized Controlled Trials (RCT) are a key method through which the effects of healthcare interventions are evaluated. However, it has been found that the management of such trials are fraught with challenges. Trials take longer than expected to reach completion and many trials fail due to not being able to reach the planned sample size within the set duration and funding allocated to the trial. If a trial is extended to reach a credible sample size, extra funding is required. This lagging of trial conclusion leads to the delay of the use of the trial results in clinical practice. It has also been found that after rapid recruitment, staff and facilities are under pressure to accommodate trial participants returning for follow-up assessments and additional staff must be hired on short notice. The aim of this paper is to present the outcome of a study to develop a decision support system that will aid in the management of a medical trial. The tool is designed and developed by following the system development life cycle (SDLC) methodology. The tool was developed by partnering with the South African Medical Research Council (SAMRC) who is currently conducting a medical trial regarding AIDS and diabetic treatment combined with counseling.","PeriodicalId":165912,"journal":{"name":"2018 3rd Biennial South African Biomedical Engineering Conference (SAIBMEC)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124446390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Towards a GSM enabled remote monitoring medical system 实现GSM远程监控医疗系统

2018 3rd Biennial South African Biomedical Engineering Conference (SAIBMEC) Pub Date : 2018-04-01 DOI: 10.1109/SAIBMEC.2018.8363195

D. Tshali, M. Sumbwanyambe, T.S. Hlalelef

引用次数: 1

Improving the diagnosis of infective endocarditis: The development of, and safety testing for, a novel blood culture device 提高感染性心内膜炎的诊断:一种新型血培养装置的研制及其安全性测试

2018 3rd Biennial South African Biomedical Engineering Conference (SAIBMEC) Pub Date : 2018-04-01 DOI: 10.1109/SAIBMEC.2018.8363181

Jane Moses, J. Muller, A. Doubell

{"title":"Improving the diagnosis of infective endocarditis: The development of, and safety testing for, a novel blood culture device","authors":"Jane Moses, J. Muller, A. Doubell","doi":"10.1109/SAIBMEC.2018.8363181","DOIUrl":"https://doi.org/10.1109/SAIBMEC.2018.8363181","url":null,"abstract":"Rapid identification and treatment of the causative organism is key in the successful treatment of bacterial infection. This can be difficult in conditions such as infective endocarditis when the organisms are circulating in low concentrations. In such conditions a delay in identifying the organism and initiating appropriate antimicrobial treatment is associated with a worse outcome. Blood culture yields may be improved by the development of a blood culture device (BCD) specifically for this purpose. This study aimed to develop a BCD and test it in vivo on a sheep model for function and safety. A blood culture device (BCD) was designed to allow an increased volume of blood (100mL) to circulate under turbulent conditions over a large surface area to optimize bacterial exposure. To prevent clotting during sampling the BCD was preloaded with heparin saline. The efficacy and safety of the developed BCD was tested on an animal model of five sheep. All five developed BCDs functioned well when tested on the sheep model. A volume of 100mL of blood was circulated through each device without clotting. The sheep did not display any clinical or biochemical evidence of bleeding or bleeding risk during or after sampling. This study confirms that a BCD can be developed through which an increased volume of blood can be circulated under turbulent conditions over a large surface area without clotting during sampling and without exposing the subject to a hemorrhagic risk.","PeriodicalId":165912,"journal":{"name":"2018 3rd Biennial South African Biomedical Engineering Conference (SAIBMEC)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116859615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0