Ophthalmologica Indonesiana最新文献

SURGICAL MANAGEMENT IN ESOTROPIA AT CIPTO MANGUNKUSUMO HOSPITAL: A 4-YEAR OBSERVATION ON CHARACTERISTIC AND RESULT CIPTO MANGUNKUSUMO医院的内斜视手术治疗：4年来的特征和结果观察

Ophthalmologica Indonesiana Pub Date : 2024-04-02 DOI: 10.35749/9sanvy75

Firdha Malisa Fauzia, Anna Puspitasari Bani

{"title":"SURGICAL MANAGEMENT IN ESOTROPIA AT CIPTO MANGUNKUSUMO HOSPITAL: A 4-YEAR OBSERVATION ON CHARACTERISTIC AND RESULT","authors":"Firdha Malisa Fauzia, Anna Puspitasari Bani","doi":"10.35749/9sanvy75","DOIUrl":"https://doi.org/10.35749/9sanvy75","url":null,"abstract":"Introduction: Esotropia, although have low prevalence in Indonesia, give significant impacts on its sufferer, and due to the wide range of types creates numerous options for surgery without much consensus. Success rates of the surgery also varied depends on many factors. This study aims to evaluate clinical characteristics, success rate in esotropia surgery, and factors that may influence the outcome.\u0000Methods: A retrospective descriptive study based on secondary data from medical records of child and adult esotropia patients who underwent surgery from January 2018 to December 2021.\u0000Result: Of 68 patients included in the study, 60.2% were adults. More than half of patients have an onset before 7 years of age, though amblyopia only affects 29.4% of patients. Squinted-eye was the chief complaint in most patients (76.5%). One-third of patients had basic type esotropia and 59.7% had large preoperative deviation. Unilateral procedure was done in 50% of patients. The surgery success rate reached 65% with good stability on 8 months of follow-up. Better results were seen in congenital and basic type esotropia than in other types. Although none of the believed influenced factors affecting outcome were significant statistically, duration <5 years and preoperative deviation <50 PD had a higher success rate of 75% and 84.6%.\u0000Conclusion: Esotropia surgery in Cipto Mangunkusumo hospital were performed majorly in adults with large pre-operative deviations, mostly by unilateral procedure of recession and resection. The surgeries yield good results and stability, with shorter duration and smaller preoperative deviation giving higher success rates.","PeriodicalId":165753,"journal":{"name":"Ophthalmologica Indonesiana","volume":"202 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140751180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

NEUROOPHTHALMOLOGIC MANIFESTATIONS AMONG 195 PATIENTS WITH INTRACRANIAL TUMOR AT NATIONAL REFERRAL HOSPITAL 国家转诊医院 195 名颅内肿瘤患者的神经眼科表现

Ophthalmologica Indonesiana Pub Date : 2024-04-02 DOI: 10.35749/r4yg5d37

Dita Permatasari, S. Nusanti

{"title":"NEUROOPHTHALMOLOGIC MANIFESTATIONS AMONG 195 PATIENTS WITH INTRACRANIAL TUMOR AT NATIONAL REFERRAL HOSPITAL","authors":"Dita Permatasari, S. Nusanti","doi":"10.35749/r4yg5d37","DOIUrl":"https://doi.org/10.35749/r4yg5d37","url":null,"abstract":"Introduction & Objective: Intracranial tumor might show neuroophthalmological manifestations. Early detection and prompt treatment could alter the visual outcome. Ophthalmologists need to be aware of neuroophthalmological features commonly found among patients with intracranial tumor. This study revealed those signs and symptoms.\u0000Methods: Study was done in tertiary referral hospital. Subjects were patients with intracranial tumor attending neuroophthalmology clinic between the specified period. It was a descriptive study using retrospective data of the patient’s initial visit to the clinic. Data was retrieved from the medical record archive and electronic health record.\u0000Results : There were 195 patients, 67.7% of them were women, with average age 43.4 years old. Half the patients arrived within 6 months after eye related symptoms occurred and the referring physicians was equal between ophthalmologists and other specialties. The most frequent symptom and sign were blurred vision and optic nerve head abnormality (atrophy, edema). Hemianopia outnumbered other patterns of visual field disturbance, yet bilateral pattern was difficult to be evaluated as most patients had either one or both eyes blind.\u0000Conclusion : Intracranial tumor was one of the diseases that could show ophthalmic signs and symptoms. Neuroophthalmological manifestations in those cases was related to the extraocular process and the relevant pathway affected by the tumor.","PeriodicalId":165753,"journal":{"name":"Ophthalmologica Indonesiana","volume":"35 38","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140753122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FACTORS THAT INFLUENCE SURVIVAL RATE IN EXTRAOCULAR RETINOBLASTOMA PATIENTS AT CIPTO MANGUNKUSUMO HOSPITAL : 2018 影响 CIPPO MANGUNKUSUMO 医院眼外视网膜母细胞瘤患者存活率的因素 : 2018 年

Ophthalmologica Indonesiana Pub Date : 2024-04-02 DOI: 10.35749/fvstnp93

Dwie Aprina, Julie D. Barliana, D. Yulia, R. S. Sitorus

{"title":"FACTORS THAT INFLUENCE SURVIVAL RATE IN EXTRAOCULAR RETINOBLASTOMA PATIENTS AT CIPTO MANGUNKUSUMO HOSPITAL : 2018","authors":"Dwie Aprina, Julie D. Barliana, D. Yulia, R. S. Sitorus","doi":"10.35749/fvstnp93","DOIUrl":"https://doi.org/10.35749/fvstnp93","url":null,"abstract":"Introduction: Optimal therapeutic approach for extraocular retinoblastoma has not been determined. The prognosis of extraocular retinoblastoma compared with intraocular retinoblastoma remains relatively poor. The aim of our study is to describe the factors that influence the survival rate of extraocular retinoblastoma.\u0000Methods: A retrospective study. Patients diagnosed with extraocular retinoblastoma in Cipto Mangunkusumo Hospital, within 1 January to 31 December 2018 were reviewed for patient and tumor characteristic, ocular management, and patient survival.\u0000Result: During the study period, a total of 80 patients were diagnosed with retinoblastoma in our center, 41.2% had an extra-ocular extension The mean age at diagnosis was 25.57 months, with 56.7% being males. Leukocoria is the initial sign most often noticed by parents. The median lag period was 12 months. Neoadjuvant chemotherapy was performed in 96.7% of cases, that carried out an average of 3-4 cycles before enucleation/exenteration. At the end of September 2019, there were 17 deaths in our study. Overall survival was 19.82 months with a mean age of 27.6 months, whereas extraocular death time ranged from 4 months to 55 months. \u0000Conclusion: Death was more common in patients with age at first symptom less than 24 months, bilateral retinoblastoma, lag period more than 12 months, advanced stage (IVB) and delayed therapy after proptosis more than 3 months.","PeriodicalId":165753,"journal":{"name":"Ophthalmologica Indonesiana","volume":"158 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140754243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AN ATYPICAL CASE OF BILATERAL CORNEAL OPACITY: WHAT ARE THE POSSIBLE DIAGNOSIS? 双侧角膜混浊的非典型病例：可能的诊断是什么？

Ophthalmologica Indonesiana Pub Date : 2024-04-02 DOI: 10.35749/c1s1j485

Jessica Zarwan, A. M. K. Siregar, Marsha Rayfa Pintary, Syska Widyawati, Faraby Martha, Rio Rhendy

{"title":" AN ATYPICAL CASE OF BILATERAL CORNEAL OPACITY: WHAT ARE THE POSSIBLE DIAGNOSIS?","authors":"Jessica Zarwan, A. M. K. Siregar, Marsha Rayfa Pintary, Syska Widyawati, Faraby Martha, Rio Rhendy","doi":"10.35749/c1s1j485","DOIUrl":"https://doi.org/10.35749/c1s1j485","url":null,"abstract":"\u0000\u0000\u0000Introduction: Corneal opacity can be divided into inflammatory and noninflammatory entities. The clinical presentation and characteristics of a corneal opacity can often help reach a diagnosis. However, atypical cases are more challenging to diagnose. This report aims to explore an atypical case of corneal opacity and the diagnostic approach through its clinical presentation. \u0000Case Report: A thirty-seven-year-old female patient had a chief complaint of gradual blurry vision in both eyes and slowly growing whitish lesions one year prior. The patient recalled a history of bilateral eye redness two years ago. The anterior segment examination and AS-OCT revealed bilateral, smooth, oedematous pearly-white elevated opacity with well-demarcated margins at the center of the cornea, with epithelial depth. The diagnosis of corneal keloid was favored, with GDLD and SND as the differential diagnosis. In local anesthesia, the patient underwent superficial keratectomy and amniotic membrane transplantation of the right eye. On one month follow-up, the patient felt an improvement in her subjective complaints with a normal appearance of the cornea. \u0000Discussion: The atypical characteristics found in our case didn’t fit a single mold, as it shared features of post- injury hypertrophic scar, degenerative, and dystrophy. We diagnosed the patient with corneal keloid caused by suspicion of subclinical infection. Although GDLD and SND were still possible, the working diagnosis was enough to warrant a therapeutic surgical removal. \u0000Conclusion: Atypical presentations make diagnosis more challenging. However, despite improvements in diagnostic modalities, signs, and symptoms remain very helpful in reaching a working diagnosis. \u0000\u0000\u0000","PeriodicalId":165753,"journal":{"name":"Ophthalmologica Indonesiana","volume":"25 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140753296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

UNVEILING OPHTHALMOLOGICAL FINDINGS IN CORNELIA DE LANGE SYNDROME: A RARE CASE REPORT 揭示科尼莉亚-德-兰格综合征的眼科发现：罕见病例报告

Ophthalmologica Indonesiana Pub Date : 2024-04-02 DOI: 10.35749/cbyqa786

D. E. Yulia, Sabrina Tan

{"title":"UNVEILING OPHTHALMOLOGICAL FINDINGS IN CORNELIA DE LANGE SYNDROME: A RARE CASE REPORT","authors":"D. E. Yulia, Sabrina Tan","doi":"10.35749/cbyqa786","DOIUrl":"https://doi.org/10.35749/cbyqa786","url":null,"abstract":"Introduction: Cornelia de Lange syndrome (CdLS) is a rare congenital disorder with a distinctive combination of physical, cognitive, and behavioral features. This syndrome impacts multiple systems in the body, including the eyes.\u0000Case Report: A three-year-old boy with classic CdLS, emphasizing the ophthalmological findings of left eye ptosis, high myopia and astigmatism, microcornea, bilateral “dot opacities” cataracts, and tigroid fundus appearance. The patient was prescribed corrective eyeglasses to prevent amblyopia.\u0000Discussion: The clinical scoring system devised by the International CdLS Consensus Group aids in classifying CdLS cases into classic and non-classic variants, as well as guiding clinical genetic testing decisions. In all instances of suspected or confirmed CdLS, it is imperative that an ophthalmologist performs an initial eye examination promptly. Therefore, acquiring familiarity with the potential ophthalmological findings of CdLS is crucial. Common ocular presentations encompass features such as synophrys, thick eyebrows, long eyelashes, ptosis, myopia, microcornea, nasolacrimal duct obstruction, peripapillary pigment ring, and blepharitis. Meanwhile, less frequently encountered ocular manifestations include hyperopia and astigmatism, cataracts, microphalmia, glaucoma, optic nerve pallor and hypoplasia, nystagmus, and strabismus.\u0000Conclusion: Timely diagnosis, precise interventions, and regular ophthalmological monitoring are pivotal in preventing complications and enhancing visual function, thus improving the quality of life of individuals with CdLS.","PeriodicalId":165753,"journal":{"name":"Ophthalmologica Indonesiana","volume":"101 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140753029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

VISUAL OUTCOME OF TRAUMATIC OPTIC NEUROPATHYAFTER STEROID TREATMENT IN KARIADI HOSPITAL 卡里亚迪医院类固醇治疗后创伤性视神经病变的视觉效果

Ophthalmologica Indonesiana Pub Date : 2024-04-02 DOI: 10.35749/1hn23p60

Isnia Rahmi Roosdhantia, Riski Prihatningtias

{"title":"VISUAL OUTCOME OF TRAUMATIC OPTIC NEUROPATHYAFTER STEROID TREATMENT IN KARIADI HOSPITAL","authors":"Isnia Rahmi Roosdhantia, Riski Prihatningtias","doi":"10.35749/1hn23p60","DOIUrl":"https://doi.org/10.35749/1hn23p60","url":null,"abstract":"Introduction: The occurrence of Traumatic Optic Neuropathy (TON) often occurs in the form of head injuries resulting from traffic accidents. TON is an important cause of impaired visual function which may be improved with steroid therapy.\u0000Objective: To determine the visual outcome in patients with TON treated with steroids in Kariadi Hospital, Semarang\u0000Methods: This research was a retrospective study. Thirty patients (20 males and 10 females) with TON in ophthalmology clinic, Kariadi Hospital Semarang between Januari 2019 and December 2020. Visual acuity, contrast sensitivity and color blindness test were included data from medical record. Steroid therapy were divided into 3 groups. Intraveous steroid injection alone, intravenous steroid followed with oral steroid, and oral steroid alone. The Wilcoxon and paired-t test as comparison test of pre-post therapy in one group and friedman test as comparison test in 3 groups.\u0000Results: There were 5 cases that received intravenous steroid, 18 cases received intravenous steroid with oral steroid, and 7 cases received oral steroid. There were difference visual acuity in intravenous steroid with oral steroid (p = 0.001), visual acuity in oral steroid (p = 0.017), and color blindness test in intravenous steroid with oral steroid in pre-post therapy groups (p = 0.036). There were no difference in visual acuity, color blindness test, and contrast sensitivity between pre-post therapy groups when compared between 3 groups (p= 0.692, p =0.368, p=0.273).\u0000Conclusion: Patients with TON had better visual outcome after treated with intravenous steroid followed with oral steroid.","PeriodicalId":165753,"journal":{"name":"Ophthalmologica Indonesiana","volume":"28 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140752707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ocular Toxocariasis in The Anterior Chamber of The Eye 眼球前腔的眼部弓形虫病

Ophthalmologica Indonesiana Pub Date : 2024-02-12 DOI: 10.35749/97195m22

Monica Camilla Chandra, A. Md, Laya Rares, MD

{"title":"Ocular Toxocariasis in The Anterior Chamber of The Eye","authors":"Monica Camilla Chandra, A. Md, Laya Rares, MD","doi":"10.35749/97195m22","DOIUrl":"https://doi.org/10.35749/97195m22","url":null,"abstract":"Introduction : Ocular toxocariasis (OT) is a zoonotic infection caused by Toxocara canis and Toxocara cati. Dogs and cats, the definitive hosts of the roundworm, pass unembryonated eggs via their feces into the environment (often into the soil). Transmission to humans occurs through ingestion of soil or contaminated food, or the fecal– oral route. \u0000Case Illustration : A 14 years old male presented with pain and redness in the right eye 2 months prior to the visit. Complaints are redness, itching, and pain especially in the night on the right eye. The patient had habits of eating raw meat and walking around in dirt without any footwear. Ophthalmologic examination showed a toxocara sp. larvae in the anterior chamber of the right eye. This patient treated with surgical removal of the worm, given antihelminth and topical corticosteroid. \u0000Discussion : Toxocariasis results from infection with Toxocara cati (an intestinal parasite of cats) or Toxocara canis (an intestinal parasite of dogs). Children acquire the disease by close association with pets and by eating dirt (pica) contaminated with Toxocara ova. The ingested ova form larvae that penetrate the intestinal mucosa and gain access to the systemic circulation and finally to the eye. Systemic or local corticosteroids should be given when there is evidence of significant intraocular inflammation. \u0000Conclusion : This case described a patient who was diagnosed with a living worm as foreign bodies in the right eye.","PeriodicalId":165753,"journal":{"name":"Ophthalmologica Indonesiana","volume":"15 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139782293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SECONDARY GLAUCOMA AFTER VITREORETINAL SURGERY: A RETROSPECTIVE OBSERVASIONAL STUDY 玻璃体视网膜手术后的继发性青光眼：一项回顾性观察研究

Ophthalmologica Indonesiana Pub Date : 2024-02-12 DOI: 10.35749/49ss4368

Liani Mulasari Gunawan, R. M. Rifada, Elsa Gustianty, Sonie Umbara

{"title":"SECONDARY GLAUCOMA AFTER VITREORETINAL SURGERY: A RETROSPECTIVE OBSERVASIONAL STUDY","authors":"Liani Mulasari Gunawan, R. M. Rifada, Elsa Gustianty, Sonie Umbara","doi":"10.35749/49ss4368","DOIUrl":"https://doi.org/10.35749/49ss4368","url":null,"abstract":"Introduction & ObjectivesSecondary glaucoma is the most common complication after vitreoretinal surgery. Pars PlanaVitrectomy (PPV) is a common surgical procedure aimed at removing vitreous gel and replacing itwith variety of substances denominated tamponades. Vitreous removal and replacement may causeincreased intraocular pressure (IOP). The IOP can be reduced with medical treatment or surgery.The purpose of this study is to describe the characteristics of secondary glaucoma after vitreoretinalsurgery in National Eye Center Cicendo Hospital from January 2019 - December 2020. \u0000MethodsThis study was a retrospective descriptive study which data were obtained from medical records.Data such as age, gender, vitrectomy tamponades, IOP, onset of glaucoma, and glaucoma treatmentwere collected. \u0000ResultsOne hundred fifty-three eyes were referred to Glaucoma Unit with increasing IOP after vitreoretinalsurgery. PPV with tamponade was done in 141 eyes (92.16%) and silicone oil (SO) 1000 centistokes(cSt) was the most used tamponade in 101 eyes (66.07%). Secondary glaucoma with open angle wasthe most common type in 124 eyes (81.04%). Secondary glaucoma developed in 4-7 weeks aftersurgery, with the highest IOP recorded at 31-40 mmHg. The IOP decreased after SO evacuation withinitial glaucoma treatment in 121 eyes (79.09%), and glaucoma surgery was performed in 32 eyes(20.91%). \u0000ConclusionSilicon oil as a tamponade agent after PPV may cause rise IOP in the post-operative period.Evacuation SO needs to be done after retinal adhesion to prevent secondary glaucoma. Therefore,timely detection and anti-glaucoma treatment are important to decreased IOP, or filtration surgerycan be performed.","PeriodicalId":165753,"journal":{"name":"Ophthalmologica Indonesiana","volume":"50 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139782321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and application of targeted multiplex polymerase chain reaction to help diagnose infectious uveitis 开发和应用靶向多聚酶链反应，帮助诊断传染性葡萄膜炎

Ophthalmologica Indonesiana Pub Date : 2024-02-12 DOI: 10.35749/e3n7cx53

Rachel Ethelind

{"title":"Development and application of targeted multiplex polymerase chain reaction to help diagnose infectious uveitis","authors":"Rachel Ethelind","doi":"10.35749/e3n7cx53","DOIUrl":"https://doi.org/10.35749/e3n7cx53","url":null,"abstract":"Abstract \u0000Introduction & Objectives : Clinical pattern recognition is paramount in uveitis diagnosis. Pathogen detection from ocular fluid samples is often necessary to support infectious uveitis diagnosis, particularly in cases presenting with atypical clinical appearance. This study aims to present the process of developing targeted multiplex PCR and its application in infectious uveitis. \u0000Methods : This was a cross sectional study to evaluate the diagnostic performance of targeted multiplex PCR in infectious uveitis. We obtained ocular fluid samples and reviewed medical records of uveitis patients who underwent ocular fluid analysis at Cipto Mangunkusumo Hospital from February 2022 to March 2023. PCR detection threshold values (DNA copies/mL) were 10.9 for Mycobacterium tuberculosis (Mtb), 672 for Epstein-Barr virus, 4.77 for Cytomegalovirus, 6.37 for Toxoplasma gondii, and 5.53 for Herpes simplex virus. With every two-fold increase of pathogen selection, this method requires a half volume of extracted DNA template from aqueous/vitreous samples than uniplex PCR. The ophthalmologist selected the pathogen combination to be detected, allowing for a tailored examination. \u0000Results : Forty-seven aqueous or vitreous samples were analyzed. The positivity rate was 23.4% (11/47) with Mtb yielded the highest positivity (7/34; 20.6%). With final diagnosis as a reference, targeted multiplex PCR resulted in 32.3% sensitivity, 93.8% specificity, 90.9% positive predictive value and 19.2% negative predictive value. \u0000Conclusion : With its high specificity, targeted multiplex PCR is useful as a confirmatory but not screening tool in uveitis diagnosis. Ocular fluid analysis is an important part of stepwise diagnostic approach in uveitis.","PeriodicalId":165753,"journal":{"name":"Ophthalmologica Indonesiana","volume":"9 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139782389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How Childhood Obesity May Be Harming Your Child’s Vision: A Systematic Review of High Myopia in Obese Children and Adolescents 儿童肥胖症可能如何损害您孩子的视力？肥胖儿童和青少年高度近视的系统回顾

Ophthalmologica Indonesiana Pub Date : 2024-02-12 DOI: 10.35749/tnc8xh79

Ajeng Kartika, Seruni Hanna Ardhia, Marcelius Patria Prabaniswara, Sarah Shabrina, Rona Ali Badjrai

{"title":"How Childhood Obesity May Be Harming Your Child’s Vision: A Systematic Review of High Myopia in Obese Children and Adolescents","authors":"Ajeng Kartika, Seruni Hanna Ardhia, Marcelius Patria Prabaniswara, Sarah Shabrina, Rona Ali Badjrai","doi":"10.35749/tnc8xh79","DOIUrl":"https://doi.org/10.35749/tnc8xh79","url":null,"abstract":"Abstract \u0000Introduction & Objectives : High myopia is a severe and progressive form of myopia that can result in blindness. The prevalenceof high myopia is rising globally, and obesity has been identified as a potential risk factor, particularly in children and adolescents. This review aims to evaluate complex interplay between obesity and myopia in the young population. \u0000Methods : A systematic literature review was conducted through PubMed, Embase, and Cochrane databases using relevant keywords. Abstract-only papers, case reports/series, and review studies were excluded, and only studies published in English between 2019 - 2023 were considered. The study selection process will be presented according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow diagram. \u0000Results : This review analyzed four studies that involved 1.326.898 participants aged between 5 to 19 years. The majority of the studies found a significant association between obesity and high myopia (p<0.05). One of the studies reported that individuals with a normal BMI have a 40% lower risk of developing high myopia compared to those who are obese. Additionally, one study found that even a slightly higher BMI value, which is not yet categorized as obesity, was significantly linked to high myopia (OR 1.19; p=0.009). \u0000Conclusion : Most of the studies showed a significant association between high myopia and higher BMI, especially in cases of obesity. However, to establish a deeper understanding of the potential link between high myopia and obesity, further studies are necessary to consolidate data from a larger population and investigate the underlying pathological pathway.","PeriodicalId":165753,"journal":{"name":"Ophthalmologica Indonesiana","volume":"51 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139782394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0