Journal of neurosurgical anesthesiology最新文献

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Representation of Authors From Low and Middle-income Countries in 2 Neuroanesthesiology and Neurocritical Care Journals: A Retrospective Analysis. 来自低收入和中等收入国家的作者在两种神经麻醉学和神经危重症期刊上的代表性:回顾性分析。
IF 2.3 2区 医学
Journal of neurosurgical anesthesiology Pub Date : 2025-07-01 Epub Date: 2024-12-30 DOI: 10.1097/ANA.0000000000001017
Chandini Kukanti, Indu Kapoor, Charu Mahajan, Hemanshu Prabhakar
{"title":"Representation of Authors From Low and Middle-income Countries in 2 Neuroanesthesiology and Neurocritical Care Journals: A Retrospective Analysis.","authors":"Chandini Kukanti, Indu Kapoor, Charu Mahajan, Hemanshu Prabhakar","doi":"10.1097/ANA.0000000000001017","DOIUrl":"10.1097/ANA.0000000000001017","url":null,"abstract":"","PeriodicalId":16550,"journal":{"name":"Journal of neurosurgical anesthesiology","volume":" ","pages":"330-332"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142895397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhanced Recovery After Surgery for Patients Undergoing Craniotomy Still Needs Affirmation! 开颅手术患者术后恢复增强仍需肯定!
IF 2.3 2区 医学
Journal of neurosurgical anesthesiology Pub Date : 2025-07-01 Epub Date: 2025-02-18 DOI: 10.1097/ANA.0000000000001032
Indu Kapoor, Charu Mahajan, Hemanshu Prabhakar
{"title":"Enhanced Recovery After Surgery for Patients Undergoing Craniotomy Still Needs Affirmation!","authors":"Indu Kapoor, Charu Mahajan, Hemanshu Prabhakar","doi":"10.1097/ANA.0000000000001032","DOIUrl":"10.1097/ANA.0000000000001032","url":null,"abstract":"","PeriodicalId":16550,"journal":{"name":"Journal of neurosurgical anesthesiology","volume":" ","pages":"330"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Remimazolam on Transcranial Electrical Motor-evoked Potential in Spine Surgery: A Prospective, Preliminary, Dose-escalation Study. 雷马唑仑对脊柱手术经颅电运动诱发电位的影响:一项前瞻性、初步、剂量递增研究。
IF 2.3 2区 医学
Journal of neurosurgical anesthesiology Pub Date : 2025-07-01 Epub Date: 2024-07-18 DOI: 10.1097/ANA.0000000000000983
Shuichiro Kurita, Kenta Furutani, Yusuke Mitsuma, Hiroyuki Deguchi, Tomoaki Kamoda, Yoshinori Kamiya, Hiroshi Baba
{"title":"Effect of Remimazolam on Transcranial Electrical Motor-evoked Potential in Spine Surgery: A Prospective, Preliminary, Dose-escalation Study.","authors":"Shuichiro Kurita, Kenta Furutani, Yusuke Mitsuma, Hiroyuki Deguchi, Tomoaki Kamoda, Yoshinori Kamiya, Hiroshi Baba","doi":"10.1097/ANA.0000000000000983","DOIUrl":"10.1097/ANA.0000000000000983","url":null,"abstract":"<p><strong>Background: </strong>Some anesthetic drugs reduce the amplitude of transcranial electrical motor-evoked potentials (MEPs). Remimazolam, a new benzodiazepine, has been suggested to have little effect on MEP amplitude. This prospective, preliminary, dose-escalation study aimed to assess whether remimazolam is associated with lower MEP amplitude in a dose-dependent manner.</p><p><strong>Methods: </strong>Ten adult patients scheduled for posterior spinal fusion were included in this study. General anesthesia was induced with a continuous infusion of remifentanil and remimazolam. After the patient lost consciousness, the infusion rate of remimazolam was set to 1 mg/kg/h, and the patient underwent tracheal intubation. Baseline MEPs were recorded under 1 mg/kg/h of remimazolam in a prone position. Thereafter, the infusion rate of remimazolam was increased to 2 mg/kg/h, with a bolus of 0.1 mg/kg. Ten minutes after the increment, the evoked potentials were then recorded again. The primary endpoint was the MEP amplitude recorded in the left gastrocnemius muscle at 2 time points.</p><p><strong>Results: </strong>There was no difference in MEP amplitude recorded from the left gastrocnemius muscle before and after increasing remimazolam (median [interquartile range]: 0.93 [0.65 to 1.25] mV and 0.70 [0.43 to 1.26] mV, respectively; P =0.08). The average time from the cessation of remimazolam administration to neurological examination after surgery was 4 minutes using flumazenil.</p><p><strong>Conclusions: </strong>This preliminary study suggests that increasing remimazolam from 1 to 2 mg/kg/h might have an insignificant effect on transcranial electric MEPs.</p>","PeriodicalId":16550,"journal":{"name":"Journal of neurosurgical anesthesiology","volume":" ","pages":"325-329"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141734397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Implementation of Enhanced Recovery After Spine Surgery in High and Low/Middle-income Countries: A Systematic Review and Meta-Analysis. 高收入和中低收入国家脊柱手术后强化恢复的实施情况:系统回顾与元分析》。
IF 2.3 2区 医学
Journal of neurosurgical anesthesiology Pub Date : 2025-07-01 Epub Date: 2024-09-18 DOI: 10.1097/ANA.0000000000001006
Abhijit V Lele, Elizabeth O Moreton, Jorge Mejia-Mantilla, Samuel N Blacker
{"title":"The Implementation of Enhanced Recovery After Spine Surgery in High and Low/Middle-income Countries: A Systematic Review and Meta-Analysis.","authors":"Abhijit V Lele, Elizabeth O Moreton, Jorge Mejia-Mantilla, Samuel N Blacker","doi":"10.1097/ANA.0000000000001006","DOIUrl":"10.1097/ANA.0000000000001006","url":null,"abstract":"<p><p>In this review article, we explore the implementation and outcomes of enhanced recovery after spine surgery (spine ERAS) across different World Bank country-income levels. A systematic literature search was conducted through PubMed, Embase, Scopus, and CINAHL databases for articles on the implementation of spine ERAS in both adult and pediatric populations. Study characteristics, ERAS elements, and outcomes were analyzed and meta-analyses were performed for length of stay (LOS) and cost outcomes. The number of spine ERAS studies from low-middle-income countries (LMICs) increased since 2017, when the first spine ERAS implementation study was published. LMICs were more likely than high-income countries (HICs) to conduct studies on patients aged ≥18 years (odds ratio [OR], 6.00; 95% CI, 1.58-42.80), with sample sizes 51 to 100 (OR, 4.50; 95% CI, 1.21-22.90), and randomized controlled trials (OR, 7.25; 95% CI, 1.77-53.50). Preoperative optimization was more frequently implemented in LMICs than in HICs (OR, 2.14; 95% CI, 1.06-4.41), and operation time was more often studied in LMICs (OR 3.78; 95% CI, 1.77-8.35). Implementation of spine ERAS resulted in reductions in LOS in both LMIC (-2.06; 95% CI, -2.47 to -1.64 d) and HIC (-0.99; 95% CI, -1.28 to -0.70 d) hospitals. However, spine ERAS implementation did result in a significant reduction in costs. This review highlights the global landscape of ERAS implementation in spine surgery, demonstrating its effectiveness in reducing LOS across diverse settings. Further research with standardized reporting of ERAS elements and outcomes is warranted to explore the impact of spine ERAS on cost-effectiveness and other patient-centered outcomes.</p>","PeriodicalId":16550,"journal":{"name":"Journal of neurosurgical anesthesiology","volume":" ","pages":"242-254"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142289495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reducing Cerebrospinal Fluid Sampling Frequency and Costs in Patients With Ventriculostomy for Aneurysmal Subarachnoid Hemorrhage: A Quality Improvement Initiative. 减少脑室造瘘治疗动脉瘤性蛛网膜下腔出血患者的脑脊液采样频率和成本:质量改进倡议。
IF 2.3 2区 医学
Journal of neurosurgical anesthesiology Pub Date : 2025-07-01 Epub Date: 2025-01-03 DOI: 10.1097/ANA.0000000000001020
Victor Lin, Michael R Levitt, Joseph Zunt, Abhijit V Lele
{"title":"Reducing Cerebrospinal Fluid Sampling Frequency and Costs in Patients With Ventriculostomy for Aneurysmal Subarachnoid Hemorrhage: A Quality Improvement Initiative.","authors":"Victor Lin, Michael R Levitt, Joseph Zunt, Abhijit V Lele","doi":"10.1097/ANA.0000000000001020","DOIUrl":"10.1097/ANA.0000000000001020","url":null,"abstract":"<p><strong>Background: </strong>We implemented a quality improvement project to transition from routine cerebrospinal fluid (CSF) sampling to indication-based sampling in aneurysmal subarachnoid hemorrhage (aSAH) patients with an external ventricular drain (EVD).</p><p><strong>Methods: </strong>Forty-seven patients were assessed across 2 epochs: routine (n=22) and indication-based (n=25) CSF sampling. The primary outcome was the number of CSF samples, and secondary outcomes included cost reductions and ventriculostomy-associated infections.</p><p><strong>Results: </strong>Patient characteristics were similar in the routine and indication-based sampling groups, as was the mean (SD) EVD duration (13.86 [5.28] days vs. 12.44 [4.78] days, respectively; P =0.936). One hundred eight CSF samples were collected during the quality improvement project; 81 in the routine sampling period and 27 in the indication-based sampling period. The median (interquartile range) CSF sampling rate reduced from 4 (3 to 4) per patient during routine sampling to 1 (0 to 2) during indication-based sampling (odds ratio: 0.19; 95% CI: 0.08-0.46; P <0.001), representing a 73% reduction in the number of samples after the transition to indication-based sampling. Each CSF sample cost $723, resulting in total sampling costs in the routine and indication-based sampling periods of $58,571 and $19,524, respectively. Therefore, the mean cost per patient was significantly higher in the routine sampling period than in the indication-based period ($2772 [$615] vs. $889 [$165], respectively; P =0.007). There were no ventriculostomy-associated infections in either period.</p><p><strong>Conclusion: </strong>Transitioning from routine to indication-based CSF sampling in aSAH patients with an EVD reduced sampling frequency and associated costs without increasing infection rates.</p>","PeriodicalId":16550,"journal":{"name":"Journal of neurosurgical anesthesiology","volume":" ","pages":"313-318"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142921866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidural Blood Patch for the Treatment of Spontaneous Intracranial Hypotension: A Case Series. 硬膜外血贴治疗自发性颅内低血压:病例系列。
IF 2.3 2区 医学
Journal of neurosurgical anesthesiology Pub Date : 2025-07-01 Epub Date: 2024-07-19 DOI: 10.1097/ANA.0000000000000981
Maria Gomez, Manas Sharma, Tommy Lik Hang Chan, Geoff Bellingham, Jason Chui
{"title":"Epidural Blood Patch for the Treatment of Spontaneous Intracranial Hypotension: A Case Series.","authors":"Maria Gomez, Manas Sharma, Tommy Lik Hang Chan, Geoff Bellingham, Jason Chui","doi":"10.1097/ANA.0000000000000981","DOIUrl":"10.1097/ANA.0000000000000981","url":null,"abstract":"<p><strong>Background: </strong>Epidural blood patch (EBP) is frequently used for the treatment of spontaneous intracranial hypotension (SIH) and anesthesiologists are often involved in performing such procedures. However, the optimal technique and approach of EBP remains uncertain.</p><p><strong>Methods: </strong>This case series included adult patients with SIH who underwent EBPs at London Health Science Centre, Ontario, Canada between 2010 and 2022. Demographics, clinical presentations, investigations, and EBP treatment details were collected and analyzed. Univariate analysis was used to investigate the association of the variables with the likelihood of EBP 1-month efficacy and the efficacy duration of EBP.</p><p><strong>Results: </strong>The study included 36 patients with SIH who received at least 1 EBP. EBPs provided immediate relief in almost all patients, albeit with diminishing effects over time. The 1-month efficacy improved with increasing number of EBP attempts ( P =0.032, Fisher exact test), though no particular EBP technique or volume of injectate was associated with better efficacy ( P =0.38, Fisher exact test). Though permanent resolution of symptoms was observed in only 24 of 82 EBPs (29%), 24 of 36 patients (67%) had permanent symptom resolution following repeated EBPs.</p><p><strong>Conclusions: </strong>EBP is a promising treatment and symptomatic relief option in patients suffering from the debilitating symptoms of SIH. Tailored EBP techniques, including use of targeted higher volume EBP and a multi-level catheter guided technique for refractory cases, showed efficacy in our institutional setting. Despite its limitations, this study contributes valuable insights and experiences into the use of EBP for treatment of SIH.</p>","PeriodicalId":16550,"journal":{"name":"Journal of neurosurgical anesthesiology","volume":" ","pages":"271-278"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141723781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcome of Aneurysmal Subarachnoid Hemorrhage Not Altered With Transatlantic Airplane Transfer: A Bicentric Matched Case-control Study. 跨大西洋飞机转运不会改变动脉瘤性蛛网膜下腔出血的预后:一项双中心匹配病例对照研究。
IF 2.3 2区 医学
Journal of neurosurgical anesthesiology Pub Date : 2025-07-01 Epub Date: 2024-07-24 DOI: 10.1097/ANA.0000000000000984
Frédéric Martino, Milan Trainel, Jessica Guillaume, Aurélien Schaffar, Simon Escalard, Adrien Pons, Nicolas Engrand
{"title":"Outcome of Aneurysmal Subarachnoid Hemorrhage Not Altered With Transatlantic Airplane Transfer: A Bicentric Matched Case-control Study.","authors":"Frédéric Martino, Milan Trainel, Jessica Guillaume, Aurélien Schaffar, Simon Escalard, Adrien Pons, Nicolas Engrand","doi":"10.1097/ANA.0000000000000984","DOIUrl":"10.1097/ANA.0000000000000984","url":null,"abstract":"<p><strong>Objective: </strong>It is recommended that ruptured cerebral aneurysms are treated in a high-volume center within 72 hours of ictus. We assessed the impact of long-distance aeromedical evacuation in patients presenting aSAH.</p><p><strong>Methods: </strong>This case-control study compared patients with aneurysmal subarachnoid hemorrhage (aSAH) who had a 6750 km air transfer from Guadeloupe (a Caribbean island) to Paris, France, for neurointerventional management in a tertiary center with a matched cohort from Paris region treated in the same center over a 10-year period (2010 to 2019). The 2 populations were matched on age, sex, World Federation of Neurological Surgeons score, and Fisher score. The primary outcome was a 1-year modified Rankin Scale score ≤3. Secondary outcomes included time from diagnosis to securing aneurysm, 1-year mortality, and a cost analysis.</p><p><strong>Results: </strong>Among 128 consecutive aSAH transferred from Guadeloupe, 93 were matched with 93 patients from the Paris area. The proportion of patients with 1-year modified Rankin Scale ≤3 (75% vs 82%, respectively; P = 0.5) and 1-year mortality (18% vs 14%, respectively; P = 0.2) was similar in the Guadeloupe and Paris groups. The median (interquartile range: Q1, Q3) time from diagnosis to securing the aneurysm was higher in the patients from Guadeloupe than those from Paris (48 [30, 63] h vs 23 [12, 24] h, respectively; P < 0.001). Guadeloupean patients received mechanical ventilation (58% vs 38%; P < 0.001) and external ventricular drainage (55% vs 39%; P = 0.005) more often than those from Paris. The additional cost of treating a Guadeloupe patient in Paris was estimated at 7580 Euros or 17% of the estimated cost in Guadeloupe.</p><p><strong>Conclusions: </strong>Long-distance aeromedical evacuation of patients with aSAH from Guadeloupe to Paris resulted in a 25-hour increase in time to aneurysm coiling embolization time but did not impact 1-year functional outcomes or mortality.</p>","PeriodicalId":16550,"journal":{"name":"Journal of neurosurgical anesthesiology","volume":" ","pages":"279-287"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12147728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141759199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bridging the Global Divide: Amplifying Voices of Low and Middle Income Countries in Perioperative Neuroscience Research. 弥合全球鸿沟:扩大中低收入国家在围手术期神经科学研究中的声音。
IF 2.3 2区 医学
Journal of neurosurgical anesthesiology Pub Date : 2025-07-01 Epub Date: 2025-06-09 DOI: 10.1097/ANA.0000000000001040
Alana M Flexman
{"title":"Bridging the Global Divide: Amplifying Voices of Low and Middle Income Countries in Perioperative Neuroscience Research.","authors":"Alana M Flexman","doi":"10.1097/ANA.0000000000001040","DOIUrl":"https://doi.org/10.1097/ANA.0000000000001040","url":null,"abstract":"","PeriodicalId":16550,"journal":{"name":"Journal of neurosurgical anesthesiology","volume":"37 3","pages":"241"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid Ventricular Pacing for Clipping of Intracranial Aneurysms: A Single-centre Retrospective Case Series. 夹闭颅内动脉瘤时的快速心室起搏:单中心回顾性病例系列。
IF 2.3 2区 医学
Journal of neurosurgical anesthesiology Pub Date : 2025-07-01 Epub Date: 2024-08-27 DOI: 10.1097/ANA.0000000000000988
Malavan Ragulojan, Gregory Krolczyk, Safa Al Aufi, Alick P Wang, Daniel I McIsaac, Shawn Hicks, John Sinclair, Adele S Budiansky
{"title":"Rapid Ventricular Pacing for Clipping of Intracranial Aneurysms: A Single-centre Retrospective Case Series.","authors":"Malavan Ragulojan, Gregory Krolczyk, Safa Al Aufi, Alick P Wang, Daniel I McIsaac, Shawn Hicks, John Sinclair, Adele S Budiansky","doi":"10.1097/ANA.0000000000000988","DOIUrl":"10.1097/ANA.0000000000000988","url":null,"abstract":"<p><strong>Objective: </strong>Multiple strategies exist to facilitate microdissection and obliteration of intracranial aneurysms during microsurgical clipping. Rapid ventricular pacing (RVP) can be used to induce controlled transient hypotension to facilitate aneurysm manipulation. We report the indications and outcomes of intraoperative RVP for clipping of ruptured and unruptured complex aneurysms.</p><p><strong>Methods: </strong>We completed a retrospective review of adult patients who underwent RVP-facilitated elective and emergent microsurgical aneurysm clipping by a single senior neurosurgeon between 2016 and 2023. Intraoperative RVP was performed at a rate of 150 to 200 beats per minute through a transvenous pacing wire and repeated as needed based on surgical requirements. Intraoperative procedural and pacing data and perioperative cardiac and neurosurgical variables were collected.</p><p><strong>Results: </strong>Forty patients were included in this study. The median (interquartile range) number of pacing episodes per patient was 8 (5 to 14), resulting in a median mean arterial pressure of 37 (30 to 40) mm Hg during RVP. One patient developed wide complex tachycardia intraoperatively, which resolved after cardioversion. Fifteen out of 36 (42%) patients who had postoperative troponin measurements had at least one troponin value above the 99th percentile upper reference limit. One patient had markedly elevated troponin with anterolateral ischemia in the context of massive postoperative intracranial hemorrhage. There were no other documented intraoperative or postoperative cardiac events.</p><p><strong>Conclusions: </strong>This retrospective case series suggests that RVP could be an effective adjunct for clipping of complex ruptured and unruptured aneurysms, associated with transient troponin rise but rare postoperative cardiac complications.</p>","PeriodicalId":16550,"journal":{"name":"Journal of neurosurgical anesthesiology","volume":" ","pages":"288-295"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142073099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transfusion Thresholds in Patients With Neurological Injury: Balancing Oxygen Delivery and Risk. 神经损伤患者的输血阈值:平衡氧输送和风险。
IF 2.3 2区 医学
Journal of neurosurgical anesthesiology Pub Date : 2025-07-01 Epub Date: 2025-05-01 DOI: 10.1097/ANA.0000000000001039
Cara Rathmell, Susana Vacas
{"title":"Transfusion Thresholds in Patients With Neurological Injury: Balancing Oxygen Delivery and Risk.","authors":"Cara Rathmell, Susana Vacas","doi":"10.1097/ANA.0000000000001039","DOIUrl":"10.1097/ANA.0000000000001039","url":null,"abstract":"<p><p>Transfusion strategies in neurocritical care require a delicate and nuanced balance between optimizing oxygen delivery to the injured brain and minimizing transfusion-associated risks. Although restrictive transfusion protocols are widely adopted in critical care, their applicability to patients with neurological injury remains the subject of debate. Anemia may exacerbate cerebral hypoxia, potentially worsening neurological outcomes, yet transfusion carries risks such as thrombosis, immune modulation, and increased intracranial pressure. Studies comparing liberal and restrictive transfusion strategies in neurocritical care have yielded mixed results, with most settling on the noninferiority of a restrictive approach while still considering a higher threshold for particular subgroups. This focused review will examine the current evidence on transfusion strategies in neurocritically ill patients and highlight key areas for future research.</p>","PeriodicalId":16550,"journal":{"name":"Journal of neurosurgical anesthesiology","volume":" ","pages":"265-270"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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