{"title":"Retracted: Early Diagnosis of Breast Cancer Using Image Processing Techniques","authors":"Journal of Nanomaterials","doi":"10.1155/2023/9838616","DOIUrl":"https://doi.org/10.1155/2023/9838616","url":null,"abstract":"<jats:p />","PeriodicalId":16442,"journal":{"name":"Journal of Nanomaterials","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135271406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Md. Zobair Al Mahmud, Md. Didarul Islam, Md Hosne Mobarak
{"title":"The Development of Eco-Friendly Biopolymers for Use in Tissue Engineering and Drug Delivery","authors":"Md. Zobair Al Mahmud, Md. Didarul Islam, Md Hosne Mobarak","doi":"10.1155/2023/9270064","DOIUrl":"https://doi.org/10.1155/2023/9270064","url":null,"abstract":"Tissue engineering and drug delivery have emerged as promising fields that hold the potential to revolutionize modern healthcare. The widespread use of synthetic polymers in these applications raises concerns about their environmental impact and biocompatibility. In response, researchers have shifted their focus toward the development of eco-friendly biopolymers as viable alternatives. This review paper aims to comprehensively analyze the progress made in the utilization of biopolymers for tissue engineering and drug delivery, with an emphasis on their ecological advantages and biomedical performance. The review begins by exploring the diverse sources of biopolymers, such as proteins, polysaccharides, and nucleic acids, derived from renewable resources, agricultural waste, etc. The discussion then delves into the unique properties of these biopolymers, including their biodegradability, nontoxic nature, and potential for controlled drug release. The incorporation of biopolymers in tissue engineering scaffolds is critically examined. The review also explores the role of biopolymers in the drug delivery systems, with a focus on nanoparticles, microparticles, hydrogels, and films. The capability of biopolymers to encapsulate and protect therapeutic agents, as well as their controlled release, is discussed in the context of targeted drug delivery and improved therapeutic outcomes. This paper highlights the challenges and future perspectives in the field of eco-friendly biopolymers for tissue engineering and drug delivery. Promising advancements in biofabrication techniques, nanotechnology, and personalized medicine are identified as key drivers for the rapid translation of these materials into the clinical applications. The development of eco-friendly biopolymers offers a sustainable and bio-safe alternative to the traditional synthetic polymers in tissue engineering and drug delivery. This comprehensive review underscores the crucial role of biopolymers in fostering advancements in regenerative medicine and therapeutic interventions while prioritizing environmental preservation and human health.","PeriodicalId":16442,"journal":{"name":"Journal of Nanomaterials","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135928902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Silver Nanoparticles Biosynthesized Using Azadirachta indica Fruit and Leaf Extracts: Optimization, Characterization, and Anticancer Activity","authors":"Njud S. Alharbi, Nehad S. Alsubhi","doi":"10.1155/2023/9916777","DOIUrl":"https://doi.org/10.1155/2023/9916777","url":null,"abstract":"Silver nanoparticles (AgNPs) are becoming increasingly important for various crucial applications, including antimicrobial, anticancer, catalytic, and anti-inflammatory. AgNPs biosynthesized from plant extracts have attracted considerable attention because of their eco-friendliness, simplicity, cost-effectiveness, and stability. This study investigated the potential of using fruit and leaf extracts of the medicinal plant Azadirachta indica as a capping and reducing agent for the biosynthesis of AgNPs. The size, shape, and optical properties of AgNPs significantly affect their chemical, physical, and biological activity. Therefore, this study optimized the biosynthesis conditions as a first attempt for A. indica fruit extracts to produce AgNPs with precise morphology. Subsequently, the biologically manufactured AgNPs were characterized using suitable techniques. Their potential anticancer activities were examined against in vitro human lung and breast cancer (H1975 and MCF-7) cell lines. The AgNPs were stable, with a high yield and a spherical shape, ranging in size from 14 to 19 nm and exhibiting an absorption band between 420 and 440 nm. The AgNPs biosynthesized using A. indica fruit and leaf extracts were shown to be highly toxic against in vitro H1975, with IC50 of 62.2 and 91 µg/mL, respectively. The IC50 values were 67.5 and 68.7 µg/mL when testing against the MCF-7 cells. These findings suggest that plant-derived nanoparticles have enormous potential for future biomedical applications, which warrants further investigation.","PeriodicalId":16442,"journal":{"name":"Journal of Nanomaterials","volume":"133 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134907175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retracted: Evaluation of Physicothermal Properties of Silicone Oil Dispersed with Multiwalled Carbon Nanotubes and Data Prediction Using ANN","authors":"Journal of Nanomaterials","doi":"10.1155/2023/9813208","DOIUrl":"https://doi.org/10.1155/2023/9813208","url":null,"abstract":"<jats:p />","PeriodicalId":16442,"journal":{"name":"Journal of Nanomaterials","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136062729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retracted: Structural and Optical Properties of CdSe/CdTe Core-Shell Quantum Dots","authors":"Journal of Nanomaterials","doi":"10.1155/2023/9854379","DOIUrl":"https://doi.org/10.1155/2023/9854379","url":null,"abstract":"<jats:p />","PeriodicalId":16442,"journal":{"name":"Journal of Nanomaterials","volume":"246 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136062735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retracted: Experimental Investigation of Spirulina Microalgae Biodiesel with Metal Nanoadditive on Single-Cylinder Diesel Engine","authors":"Journal of Nanomaterials","doi":"10.1155/2023/9756721","DOIUrl":"https://doi.org/10.1155/2023/9756721","url":null,"abstract":"<jats:p />","PeriodicalId":16442,"journal":{"name":"Journal of Nanomaterials","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136062910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retracted: Nanometal-Based Magnesium Oxide Nanoparticle with C. vulgaris Algae Biodiesel in Diesel Engine","authors":"Journal of Nanomaterials","doi":"10.1155/2023/9861247","DOIUrl":"https://doi.org/10.1155/2023/9861247","url":null,"abstract":"<jats:p />","PeriodicalId":16442,"journal":{"name":"Journal of Nanomaterials","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136062718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariana Georgina Muñoz-Carrillo, Cristina Garcidueñas-Piña, Melannie Montserrat Pedroza-Jimenez, Roberto Carlos Valerio-García, Ana Laura Carbajal-Hernández, Galdino Andrade, José Francisco Morales-Dominguez
{"title":"Toxicity of Silver Nanoparticles Synthesized from Opuntia ficus-indica on Danio rerio and Arabidopsis thaliana and Their Antimicrobial Activity","authors":"Mariana Georgina Muñoz-Carrillo, Cristina Garcidueñas-Piña, Melannie Montserrat Pedroza-Jimenez, Roberto Carlos Valerio-García, Ana Laura Carbajal-Hernández, Galdino Andrade, José Francisco Morales-Dominguez","doi":"10.1155/2023/6903787","DOIUrl":"https://doi.org/10.1155/2023/6903787","url":null,"abstract":"Silver nanoparticles (AgNPs) usefulness has been widely demonstrated in fields such as agriculture, medicine, food, and pharmaceutical industries, primarily for their antibacterial properties. AgNPs synthesized from biological extracts are as effective as those obtained by chemical methods, with the advantage that in the former fewer toxic compounds are generated for the environment. In a previous work, we synthesized AgNPs from the aqueous extract of Opuntia ficus-indica fruit peel (OfAgNPs) and tested their activity against microorganisms from a wastewater treatment plant. OfAgNPs were proposed for use as tertiary wastewater treatment; however, more needs to be known about their antimicrobial activity and toxicological potential. In the present study, the antimicrobial effect of OfAgNPs was demonstrated against reference bacterial strains of Escherichia coli (DH5α), Pseudomonas aeruginosa (ATCC 27853), and Staphylococcus aureus (ATCC 29213), and against fungi isolated in the laboratory and identified as Aspergillus sp., Colletotrichum sp., and Cladosporium sp. In addition, in this work, we report the effects of OfAgNPs produced by exposure in two model organisms: a fish, Danio rerio, and a plant, Arabidopsis thaliana. OfAgNPs in A. thaliana caused negative effects on growth and photosynthetic pigment content only when the exposure was constant and greater than 6 mg/L. However, in D. rerio, impaired caudal fin development was observed at 0.15 mg/L from 24 hr of exposure. This is evidence of the toxicological potential of OfAgNPs, so their use should be carried out in a controlled manner.","PeriodicalId":16442,"journal":{"name":"Journal of Nanomaterials","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135482877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chellapan Justin, Antony V. Samrot, Nagarajan Shobana, Mahendran Sathiyasree, Subramanian Saigeetha, Rajan Renuka Remya, Deenadhayalan Rajalakshmi, S. Prasath
{"title":"Assessment on the Toxic Effects of Chemically Synthesized SPIONs against Model Organisms","authors":"Chellapan Justin, Antony V. Samrot, Nagarajan Shobana, Mahendran Sathiyasree, Subramanian Saigeetha, Rajan Renuka Remya, Deenadhayalan Rajalakshmi, S. Prasath","doi":"10.1155/2023/4235308","DOIUrl":"https://doi.org/10.1155/2023/4235308","url":null,"abstract":"The remarkable physicochemical properties of nanomaterials have attracted researchers due to the numerous applications in the field of chemistry, biology, and physics. Despite the various applications, superparamagnetic iron oxide nanoparticles (SPIONs) are harmful to living organisms and to the environment as they are released without any safety testing. In this study, SPIONs were synthesized and further characterized. The aim of the study was to examine the toxicity of synthesized SPIONs against animal models: Zebrafish—Danio rerio, Earthworm—Eudrilus eugeniae, and Drosophila—Drosophila melanogaster through histology using Hematoxylin–Eosin and Prussian Blue staining. The accumulation of SPIONs was further quantified by using Inductively Coupled Plasma Mass Spectrometry (ICP-MS). Through histology images, it was observed that the SPIONs had caused damages and a lower concentration of 0.001–0.002 μg/ml of metal accumulation was detected in the ICP-MS analysis.","PeriodicalId":16442,"journal":{"name":"Journal of Nanomaterials","volume":"174 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135059436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Balkrishna, Akansha Rohela, Ashwani Kumar, Shalini Mishra, V. Arya, Vandana Kala, Naveen Thakur, Nikesh Thakur, A. Kumari, N. Khan
{"title":"Elucidating the Role of Plant Extracts Mediated Gold Nanoparticles as Smart Antimicrobials: Two-Way Attack","authors":"A. Balkrishna, Akansha Rohela, Ashwani Kumar, Shalini Mishra, V. Arya, Vandana Kala, Naveen Thakur, Nikesh Thakur, A. Kumari, N. Khan","doi":"10.1155/2023/4085090","DOIUrl":"https://doi.org/10.1155/2023/4085090","url":null,"abstract":"Pathogenic bacteria remain the primary health concern even after developing a broad spectrum of antibiotics. The emergence of drug-resistant strains increased mortality, perhaps resulting in a never-ending future pandemic. The researchers are currently concentrating their efforts on nanotechnology-based therapies to counteract resistance. The present review focuses on the antimicrobial characteristics of plant-mediated gold nanoparticles (Au NPs). First, the methodology and importance of green synthesis are highlighted. Variability in NPs characterization methods was identified, with dynamic light scattering, zeta potential, and thermogravimetric analysis limited to a few investigations. Second, the Au NPs synthesized using different plant extracts were found to be broad-spectrum antimicrobial agents against Pseudomonas aeruginosa, Escherichia coli, Cryptococcus neoformans, Candida glabrata, Aspergillus niger, etc. The lowest minimum inhibitory concentrations range (1.95–15.62 µg/mL) was observed with Au NPs synthesized using Thymus vulgaris extract against Staphylococcus aureus, P. aeruginosa, Bacillus subtilis, and E. coli. The effect was more pronounced with smaller NPs (<10 nm). The activity of Au NPs might be mediated through a two-way attack which includes nanoparticles’ diverse mechanisms like reactive oxygen species generation, etc., and surface-attached phytocompounds such as flavonoids, alkaloids, phenolics, terpenoids, tannins, etc. The futuristic role of nanotechnology-based interventions in managing microbial infections is imperative. Synergistic interactions of Au NPs with antibiotics, toxicity profiling, stability, and bioavailability could be major areas of NPs research.","PeriodicalId":16442,"journal":{"name":"Journal of Nanomaterials","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78788551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}