{"title":"Comparison of Jigsaw and Traditional Teaching Methods on Learning and Motivation of Laboratory Science Students of North Khorasan University of Medical Sciences in Parasitology Course in 2022","authors":"","doi":"10.32592/nkums.15.3.25","DOIUrl":"https://doi.org/10.32592/nkums.15.3.25","url":null,"abstract":"Introduction: The jigsaw method of learning is a student-centered educational method, and one of its approaches is students' active participation in the class. Therefore, the present study aimed to compare teaching with two methods of jigsaw and lectures on the learning and motivation of laboratory science students in parasitology courses. Method: This study was carried out based on a cross-sectional descriptive-analytical design. In this study, 25 laboratory science students participated and were assigned to two groups: jigsaw and traditional. In each session, the teacher assigned a topic for each member of the jigsaw groups, and the students were given a week to study the topic. Thereafter, in the educational method of jigsaw, each student explained the presented material to other members. In the traditional method, each session was conducted by a teacher. At the end, the lecture and jigsaw groups were tested with the same questions and the scores of the two groups were compared. Results: In the examination of the difference between the total score in the jigsaw and lecture groups using the non-parametric Mann-Whitney U test, the mean and median of the total scores in the jigsaw method were higher than the traditional method, and this difference was statistically significant at the 95% confidence level. Conclusion: Considering the many names of the parasitology course, hard learning, and students' complaints about the amount of content in this course, jigsaw can be a suitable method for teaching this course.","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139350684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Two Types of Aerobic Exercise Programs on NT4 Gene Expression and Motor Performance in Spinally Injured Rats","authors":"","doi":"10.32592/nkums.15.3.11","DOIUrl":"https://doi.org/10.32592/nkums.15.3.11","url":null,"abstract":"Introduction: The present research aimed to investigate the effect of four weeks of selective training on motor performance and neurotrophin4 (NT4) gene expression in the hippocampus of rats with spinal cord injury (SCI). Method: This experimental study was conducted on adult and young male Wistar rats. The animals were randomly divided into six groups (control group, healthy group with the first exercise protocol, healthy group with the second exercise protocol, SCI group, SCI group with the first exercise protocol, and SCI group with the second exercise protocol; 7 animals in each group). Firstly, animals were subjected to general anesthesia and SCI. After two weeks of recovery, two types of aerobic exercise programs were performed for four weeks. After performing the exercises, Basso Beattie Bresnahan (BBB) test and molecular tests were used to measure the expression of the NT4 gene from the hippocampus of the animals using the qRT-PCR method. Results: The BBB score in the exercise group compared to the injury group increased significantly. The expression of NT4 in the SCI group was significantly decreased compared to the control group. While, NT4 expression was increased in the SCI + exercise 1 group and in the SCI + exercise 2 group compared to the SCI group, this increased expression was not significantly different between the two groups of SCI + exercise. Conclusion: The exercise protocols of this study are effective on NT4 gene expression, as well as improving movement in animals with SCI, and could be a factor for axonal growth and neuronal survival in spinal cord injury recovery.","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139350866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of Social Health and its Relationship with Quality of Life in Medical Students of Golestan University of Medical Sciences","authors":"","doi":"10.32592/nkums.15.3.55","DOIUrl":"https://doi.org/10.32592/nkums.15.3.55","url":null,"abstract":"Introduction: Social health is the most complex aspect of health that plays a key role in the quality of social life and can be the cause of suffering or aggravation of psycho-social and physical problems. Therefore, the present study was conducted with the aim of investigating social health and its relationship with quality of life among medical students at Golestan University of Medical Sciences in 2018. Method: This descriptive-analytical and cross-sectional study was conducted using stratified random sampling. A total of 190 people were selected for non-clinical and clinical stages. Data were collected using a questionnaire to determine social health and quality of life and then analyzed with SPSS software (version 16) using the t-test, ANOVA, Mann-Whitney U test, Kruskal-Wallis test, X2, as well as Pearson and Spearman correlation analyses. The significance level was considered to be 0.05. Results: The mean age of the students was 23.06±2.28 years, and the majority (58.9%) were female. The average scores of social health and quality of life of the students were 104.16±8.47 and 90.9±13.01, respectively. Social health had a direct and significant relationship with quality of life (r=0.0482, P=0.001). Age showed an inverse relationship with social health (r=-0.17, P=0.8) and a direct relationship with quality of life (r=0.14, P=0.07). Variables of gender, ethnicity, marital status, and place of residence had no relationship with social health indicators or quality of life. Conclusion: Social health is directly related to the quality-of-life index of students. Moreover, an increase in age improves the quality of life but decreases social health.","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139354422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Emergence and Dimension of Medicalization Phenomenon in the Socio-Historical Context: With a Glance at the Dimensions of Medicalization in Iran","authors":"","doi":"10.32592/nkums.15.3.72","DOIUrl":"https://doi.org/10.32592/nkums.15.3.72","url":null,"abstract":"Introduction: Medicalization can be defined as the process by which some aspects of human life come to be recognized as medical problems, while before that, they were not considered pathological. Considering the importance of an awareness of the dimensions and consequences of medicalization, the present study aimed to securitize the historical aspects, emergence, and dimensions of medicalization with a glance at this phenomenon in Iran. Method: This descriptive-analytical study tried to address the dimensions and process of medicalization in a historical context and finally discuss the motor engines, aspects, and effects of medicalization in Iran. Results: Modern medicine and capitalism use three motor engines, including consumers, technology, and controlled medical care, to dominate and govern societies. During the last few decades, especially in the post-war period, medicalization has found its place in Iran's society with the change of cultural and consumer patterns. Conclusion: Due to the keen dependence on technology and the capitalistic paradigm, modern medicine has been affected by the discourse and capitalist view in some areas. Therefore, some aspects of human life have been redefined under the label of disease and put in the cycle of supply and demand.","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139361362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of the Effect of Aerobic and Combined Upper Body Exercises on Cardiovascular Risk Factors in Disabled Veterans with Lower Limb Amputation","authors":"","doi":"10.32592/nkums.15.3.63","DOIUrl":"https://doi.org/10.32592/nkums.15.3.63","url":null,"abstract":"Introduction: Disabled veterans with lower limb amputation are at risk of cardiovascular disease 2 to 3 times more than healthy counterparts due to physical problems and immobility. Exercise is an effective intervention in reducing cardiovascular diseases in different groups. The purpose of this research was to investigate the effect of 12 weeks of aerobic and combined upper-body exercises on cardiovascular risk factors of disabled veterans with lower limb amputation. Method: In this clinical trial, 45 disabled veterans with lower limb amputation were randomly divided into 3 groups of aerobic exercise, combined exercise, and control. The exercise groups received the desired intervention 3 sessions every week for 12 weeks by observing the overload principle in the duration, volume, and intensity. Measurements of body composition, metabolic indices, and inflammatory indices (C-reactive protein [CRP], interleukin 6 [IL-6], and vascular cell adhesion molecule [V-CAM]) were performed before and after the interventions. All statistical analyses were performed using SPSS-25 software at a significance level of P≤0.05. One-way analysis of variance, Tukey's post hoc test, and paired-sample t-test were used for intragroup and intergroup comparisons. Results: A significant improvement was observed in weight, body mass index, blood sugar, cholesterol, triglyceride, high-density lipoprotein, low-density lipoprotein, CRP, and IL-6 in the aerobic and combined training groups, compared to the control group (P≤0.05). A significant improvement was observed in the V-CAM only in the combined training group, compared to the control group (P=0.018). No significant changes were seen in aspartate transaminase and alanine transaminase after any of the interventions (P≥0.05). Conclusion: For disabled veterans with lower limb amputation, aerobic and combined upper-body exercises can have numerous benefits for the prevention of cardiovascular diseases through the improvement of cardiovascular risk factors.","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"122 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139368176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preparation and Physicochemical Evaluation of Injectable Sustained-Release Risperidone by Lipid Liquid Crystal Vehicle","authors":"","doi":"10.32592/nkums.15.3.43","DOIUrl":"https://doi.org/10.32592/nkums.15.3.43","url":null,"abstract":"Introduction: Risperidone is a highly effective medicine in patients with mental disorders. Since maintaining blood concentrations of risperidone within the therapeutic index is pivotal during treatment, these patients should receive medication daily and continuously. Method: In this study, an optimal lipid liquid crystal was designed according to the maximum release for 60 days based on different ratios of phosphatidylcholine (PC) to sorbitan monooleate (PC:SMO), tween 80 (w/w%), and tocopherol acetate (w/w%) using Design Expert software with the Central Composite Design (CCD) method. Release evaluations were conducted in vitro to compare the effects of lipid liquid crystal and Risperdal CONSTA®. The structure evaluation was also tested using polarized electron microscopy and in vitro assessment via cell culture. Results: The optimal formulation was selected based on the maximum release (100%) of the drug obtained within 2 months with a PC: SMO ratio of 58.6%, tween 0.82% (w/w), and tocopherol acetate 3.6% (w/w). A hexagonal mesophase with a dihedral structure was observed in the liquid crystal structure. No toxicity was observed in the cell culture test. Conclusion: The comparison of the results of in vitro studies of the liquid crystal formulation containing risperidone and the commercial formulation, Risperdal CONSTA®, showed that the liquid crystal system provides better and more uniform drug release for 60 days. Therefore, it can increase patient compliance and ease the problems of oral administration","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139368699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between Polymorphism in XRCC7 Gene (G6721T) and Risk of Multiple Sclerosis: A Case-control Study","authors":"","doi":"10.32592/nkums.15.2.87","DOIUrl":"https://doi.org/10.32592/nkums.15.2.87","url":null,"abstract":"Introduction: The XRCC7 gene, encoding the catalytic subunit of DNA-activated protein kinase (DNA-PKcs), is one of the most important genes in the DNA double-strand break (DSBs) repair. It is supposed that DNA repair gene malfunction is the main risk factor in various neurodegenerative diseases. The impact of XRCC7 G6721T (rs7003908) polymorphism on the splicing regulation cause mRNA instability. Therefore, the current study aimed to assess the possible association between XRCC7 G6721T polymorphism and MS susceptibility in a sample of Iranian population.\u0000Method: This case-control study was performed on 113 MS patients versus 122 healthy controls. The genotype analysis of the XRCC7 G6721T polymorphism was performed using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique.\u0000Results: A significant statistical difference in the genotypic frequencies of TT between cases and controls was found (P=0.003). The genotypic frequencies of the XRCC7 G6721T polymorphism were not significantly different in MS patients compared to the control group under the dominant and recessive genetic models. Moreover, the T allele was the risk factor for MS (P=0.002).\u0000Conclusion: Our results provide evidence for a possible link between XRCC7 and the development of MS in the Iranian population. Therefore, further studies with larger sample sizes are required to support the findings of this research.","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84311858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparing the Efficacy of Mobile Application vs. Educational Pamphlets in Awareness of Dental Trauma among Mothers Referring to Bojnourd Dental School and Private Clinics","authors":"","doi":"10.32592/nkums.15.2.22","DOIUrl":"https://doi.org/10.32592/nkums.15.2.22","url":null,"abstract":"Introduction: One of the issues that have always occupied the minds of dentists is the fate of teeth that are subjected to traumatic injuries. Parents are the primary source of timely management. Therefore, the final prognosis of an affected tooth mainly depends on the knowledge of parents, especially mothers. The present study aimed to investigate awareness of dental injuries among mothers referring to Bojnourd Dental School and private pediatric dental offices and compare the effect of two educational interventions, pamphlet and application, on dental injury management.\u0000Method: A total of 150 mothers were randomly assigned to two groups: pamphlet intervention and application intervention (n=75 in each group). After completing the informed consent forms, the questionnaires were provided to mothers. After collecting the questionnaires, pamphlets and applications with similar content regarding the management of dental injuries were provided to the two groups. One month after the interventions, the same questionnaire was completed by mothers. Therefore, pre-test and post-test results were compared.\u0000Results: A total of 146 mothers participated in this study. The mean awareness score in both the pamphlet and application groups increased significantly after the intervention (P<0.05), while there was no significant difference in the mean awareness score between the two intervention groups (P>0.05).\u0000Conclusion: As evidenced by the obtained results, parents have insufficient information about dental trauma; therefore, practical steps should be taken to raise this awareness. In our study, both pamphlets and applications were equally effective in increasing mothers' awareness of dental injuries. Of note, finding a more efficient method needs further studies","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"28 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87657338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Examining the Prevalence of Iron-deficiency Anemia in Children with Cyanotic Congenital Heart Disease Admitted to the Pediatric Heart Department of Imam Reza Hospital in Mashhad between 2011 and 2019: A Cross-sectional Observational Study","authors":"","doi":"10.32592/nkums.15.2.80","DOIUrl":"https://doi.org/10.32592/nkums.15.2.80","url":null,"abstract":"Introduction: This study was performed to investigate the frequency of iron-deficiency anemia and some related factors in children with cyanotic congenital heart disease between 2011 and 2019 in Mashhad City, Iran.\u0000Method: This cross-sectional observational study was conducted with a consensus method on children under 14 years of age. The samples were diagnosed with cyanotic congenital heart disease in the pediatric heart department of Imam Reza Hospital in Mashhad and had an oxygen saturation of less than 94%. The information from the patients' files was recorded in the questionnaire. The studied children were divided into five age groups to evaluate iron-deficiency anemia. The mean and lower limit of normal erythrocyte indices were determined, and the patients with anemia were identified based on mean corpuscular hemoglobin (MCH), mean corpuscular volume (MCV), and red blood cell distribution width (RDW). The data were statistically analyzed in SPSS23 software using Chi-square and Mann-Whitney statistical tests. A significance level of 0.05 was considered.\u0000Results: Among 250 examined patients, 90 cases were included in the study (54 boys and 36 girls). Angiography was the reason for half of these patients' referral to the hospital. The highest frequency was related to patients with tetralogy of Fallot (40%). The frequency rates of iron-deficiency anemia based on MCV and MCH erythrocyte indices were 10% and 17.8%, respectively. Moreover, 64.4% of patients had increased RDW levels. Cyanosis attacks were reported positive in 85.4% of the studied population. Of note, the frequency of cyanosis attacks was not significantly different in the two gender groups (P<0.494).\u0000Conclusion: Considering the high prevalence of iron-deficiency anemia, especially in children with congenital heart disease, the treatment of this disorder is necessary for all such children and should not be neglected","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"267 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79012840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of Models and Theories of Health Education and Health Promotion in the Prevention of Substance Abuse in Adolescents: A Systematic Review","authors":"","doi":"10.32592/nkums.15.2.71","DOIUrl":"https://doi.org/10.32592/nkums.15.2.71","url":null,"abstract":"Introduction: The purpose of this study was to investigate the effectiveness of interventions based on models and theories of health education and promotion in preventing substance abuse in adolescents.\u0000Method: A detailed search was performed in Magiran, SID, Web of Science, Scopus, Pubmed, and Google Scholar databases using related keywords to extract all studies published in this field with the time limit of January 1, 2011 to December 21, 2021. After screening the studies, 11 articles that met the inclusion criteria were examined.\u0000Results: In this research, there were 7 semi-experimental studies, 3 clinical trials, and 1 unclear study, which were conducted on first- and second-grade high school students. Educational interventions were conducted in 6 articles based on the theory of planned behavior, 2 articles based on the health belief model, 1 article based on the developed theory of rational action, 1 article based on the trans theoretical model, and 1 article based on the family interaction theory.\u0000Conclusion: The results showed that the use of different models/theories could have a positive effect on preventing substance abuse and subsequently performing health behaviors. Based on the findings, the structure of attitude and self-efficacy were introduced as the most important and strongest variables in most studies and played a crucial role in preventing substance abuse and health behavior in students","PeriodicalId":16423,"journal":{"name":"journal of north khorasan university of medical sciences","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80178046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}