Journal of NeuroInterventional Surgery最新文献

{"title":"Multicenter early United States feasibility study and periprocedural safety of LVIS EVO for the treatment of unruptured intracranial aneurysms.","authors":"Yasha Kayan, Josser E Delgado Almandoz, Alexander Copelan, Charles Matouk, M Imran Chaudry, David Altschul, Muhammed Amir Essibayi, Oded Goren, Benjamin Yim, Sam Tsappidi, Yi Jonathan Zhang, Ferdinand K Hui, Edgar A Samaniego, Andres Gudino, Adnan Siddiqui, Vinay Jaikumar, Ajit S Puri, Anna Luisa Kühn, Jasmeet Singh, Andrew Ringer, Ricardo A Hanel, Otavio Frederico De Toledo, Guilherme Dabus, M Reid Gooch, Saman Sizdahkhani, Nicholas C Field, Alexandra R Paul","doi":"10.1136/jnis-2024-021900","DOIUrl":"10.1136/jnis-2024-021900","url":null,"abstract":"<p><strong>Background: </strong>Stent development has focused recently on low-profile, self-expandable stents compatible with 0.0165 inch microcatheters. The LVIS EVO is the second-generation version of the Low-Profile Visualized Intraluminal Support (LVIS) with improved visibility and resheathability. The LVIS EVO underwent a limited premarket release (PMR) in December 2023. This study aims to report the early safety and feasibility experience with the LVIS EVO stent for the treatment of intracranial aneurysms in the United States (US).</p><p><strong>Methods: </strong>This was a multicenter, retrospective, observational study evaluating patients who underwent treatment of an intracranial aneurysm with an LVIS EVO stent after the limited PMR. All physicians who had placed an LVIS EVO stent were asked to input their cases after institutional review board approval was obtained. The data were then sent to a single center for analysis. Any patient aged 18 years or older who underwent treatment of an intracranial aneurysm with a LVIS EVO stent in the US was included from the initial PMR in December 2023 until April 2024. Patient age (or ≤90 years old), sex, preoperative modified Rankin Scale (mRS), aneurysm location, aneurysm measurements, and information about preoperative antiplatelet management were all collected. Data on periprocedural complications, 30-day mortality, discharge mRS, and length of stay were also collected.</p><p><strong>Results: </strong>Some 53 patients with 55 aneurysms underwent treatment with the LVIS EVO stent at 15 institutions. All aneurysms were unruptured. The most common location was the anterior communicating artery (35%) followed by the middle cerebral artery bifurcation (31%). All patients were on dual antiplatelet therapy. The average aneurysm size was 5.2 mm with a neck size of 3.7 mm. The smallest distal parent vessel size was 1.2 mm and 36% of stents were deployed in distal parent vessels <2 mm. All (100%) cases had successful deployment and the stent was repositioned in 10% of cases. A single stent was utilized in 91% of cases. Coils were placed in 48 cases (87.2%) and a microcatheter was jailed in 98% of those cases. Immediate Raymond Roy (RR) Class I occlusion was obtained in 33%, Class II in 22%, Class IIIa in 37%, and Class IIIb in 8% of cases. There were no delayed thromboembolic or hemorrhagic complications.</p><p><strong>Conclusions: </strong>The LVIS EVO is a braided, self-expanding, retrievable stent with enhanced visibility and smaller cell size. The drawn filled tube (DFT) technology results in improved visibility of the stent, allowing for more controlled stent positioning and visualization of vessel wall apposition. All cases in our series had complete neck coverage and good wall apposition. There were no thromboembolic or hemorrhagic complications.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":"405-409"},"PeriodicalIF":4.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141436978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contour Neurovascular System for endovascular embolization of cerebral aneurysms: a multicenter cohort study of 10 European neurovascular centers.","authors":"Christoph J Griessenauer, Sherief Ghozy, Alessandra Biondi, Constantin Hecker, Fritz Wodarg, Thomas Liebig, Tufail Patankar, Saleh Lamin, Mario Martínez-Galdámez, Christophe Cognard, Jens Fiehler, Franziska Dorn, Adam A Dmytriw, Monika Killer-Oberpfalzer","doi":"10.1136/jnis-2023-021378","DOIUrl":"10.1136/jnis-2023-021378","url":null,"abstract":"<p><strong>Background: </strong>Intrasaccular devices have become increasingly popular in the treatment of cerebral aneurysms, particularly at the bifurcation. Here we evaluate the Contour Neurovascular System, an intrasaccular device for the endovascular treatment of cerebral aneurysms, in a multicenter cohort study, the largest to the best of our knowledge.</p><p><strong>Methods: </strong>Consecutive patients with intracranial aneurysms treated with the Contour Neurovascular System between February 2017 and October 2022 at 10 European neurovascular centers were prospectively collected and retrospectively reviewed. Patient and aneurysm characteristics, procedural details, and angiographic and clinical outcomes were evaluated.</p><p><strong>Results: </strong>During the study period, 279 aneurysms (median age of patients 60 years, IQR 52-68) were treated with Contour. In 83.2% of patients the device was placed electively, whereas the remaining patients were treated in the setting of acute subarachnoid hemorrhage. The most common locations were the middle cerebral artery (26.5%) followed by the anterior communicating region (26.2%). Median aneurysm dome and neck size were 5.2 mm (IQR 4.2-7) and 3.9 mm (IQR 3-5). Contour size 7 (39%) and 9 (25%) were most used. Thromboembolic and hemorrhagic complications occurred in 6.8% and 0.4% of aneurysms, respectively. Raymond-Roy 1 and 2 occlusions at last follow-up were achieved in 63.2% and 28.3%, respectively, resulting in adequate occlusion of 91.5% of aneurysms.</p><p><strong>Conclusion: </strong>This is the largest multicenter study reporting the outcome on the Contour Neurovascular System. At 1 year, the self-evaluated data on safety and efficacy are comparable to data of existing intrasaccular devices. Contour is a promising technology in the treatment of cerebral aneurysms.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":"399-404"},"PeriodicalIF":4.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140957590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of rescue intracranial stenting versus best medical treatment alone in acute refractory large vessel occlusion: study protocol for the PISTAR multicenter randomized trial.","authors":"Kévin Premat, Agnès Dechartres, Amandine Baptiste, Alexis Guedon, Mikael Mazighi, Laurent Spelle, Christian Denier, Titien Tuilier, Hassan Hosseini, Bertrand Lapergue, Federico Di Maria, Nicolas Bricout, Hilde Henon, Benjamin Gory, Sébastien Richard, Cyril Chivot, Audrey Courselle, Stéphane Velasco, Mathias Lamy, Vincent Costalat, Caroline Arquizan, Gaultier Marnat, Igor Sibon, Stephanie Lenck, Eimad Shotar, Julien Allard, Nader Sourour, Vincent Degos, Sonia Alamowitch, Frédéric Clarençon","doi":"10.1136/jnis-2024-021502","DOIUrl":"10.1136/jnis-2024-021502","url":null,"abstract":"<p><strong>Background: </strong>Mechanical thrombectomy (MT) has become a standard treatment for acute ischemic strokes (AIS). However, MT failure occurs in approximately 10-30% of cases, leading to severe repercussions (with mortality rates up to 40% according to observational data). Among the available rescue techniques, rescue intracranial stenting (RIS) appears as a promising option.</p><p><strong>Objective: </strong>This trial is poised to demonstrate the superiority of RIS in addition to the best medical treatment (BMT) in comparison with BMT alone, in improving the functional outcomes at 3 months for patients experiencing an AIS due to a large vessel occlusion refractory to MT (rLVO).</p><p><strong>Methods: </strong>Permanent Intracranial STenting for Acute Refractory large vessel occlusions (PISTAR) is a multicenter prospective randomized open, blinded endpoint trial conducted across 11 French University hospitals. Adult patients (≥18 years) with an acute intracranial occlusion refractory to standard MT techniques will be randomized 1:1 during the procedure to receive either RIS+BMT (intervention arm) or BMT alone (control arm).</p><p><strong>Results: </strong>The primary outcome is the rate of good clinical outcome at 3 months defined as a modified Rankin Scale score ≤2 and evaluated by an independent assessor blinded to the randomization arm. Secondary outcomes include hemorrhagic complications, all adverse events, and death. The number of patients to be included is 346. Two interim analyses are planned with predefined stopping rules.</p><p><strong>Conclusion: </strong>The PISTAR trial is the first randomized controlled trial focusing on the benefit of RIS in rLVOs. If positive, this study will open new insights into the management of AIS.</p><p><strong>Trial registration number: </strong>NCT06071091.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":"360-367"},"PeriodicalIF":4.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140305832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thrombectomy for medium vessel occlusions: too far too soon?","authors":"Michael Chen, Edgar A Samaniego, Mario Martínez-Galdámez, Reade Andrew De Leacy, Joshua A Hirsch, David Fiorella, Felipe C Albuquerque","doi":"10.1136/jnis-2025-023248","DOIUrl":"10.1136/jnis-2025-023248","url":null,"abstract":"","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":"337-339"},"PeriodicalIF":4.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Onyx cast thrombectomy: bailout during thalamic AVM embolization.","authors":"Marco Colasurdo, Huanwen Chen, Gautam Edhayan, Hashem Shaltoni, Peter Kan","doi":"10.1136/jnis-2023-020832","DOIUrl":"10.1136/jnis-2023-020832","url":null,"abstract":"<p><p>Microsurgical resection, radiosurgery, and endovascular embolization are the three different treatment approaches to cerebral arteriovenous malformations (AVMs). Although microsurgical resection remains the most desirable curative option and radiosurgery is often first choice in deep located/eloquent unruptured AVMs, transarterial or transvenous embolization may be pursued for ruptured AVMs not amenable to surgical resection. Most complications during endovascular treatment are related to hemorrhage; however, liquid embolic fragment migration or parent vessel occlusion are also possible and can lead to ischemic events. We present a case of endovascular Onyx (Medtronic, Minnesota, USA) embolization of a ruptured thalamic AVM complicated by Onyx reflux into the proximal posterior cerebral artery causing complete vascular occlusion. We demonstrate a bailout technique1-4 using combined stent-retriever and aspiration catheter to dislodge and retrieve the refluxed Onyx cast while maintaining total occlusion of the initially targeted arterial AVM feeder (video 1). neurintsurg;17/4/444/V1F1V1Video 1.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":"444"},"PeriodicalIF":4.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41147987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical thrombectomy in basilar artery occlusions: impact of first-line strategy as a function of the occlusion level.","authors":"Louis Tournier, Jonathan Cortese, Arturo Consoli, Laurent Spelle, Gaultier Marnat, Mariana Sarov, Francois Zhu, Sebastien Soize, Julien Burel, Géraud Forestier, Simon Escalard, Raoul Pop, Baptiste Bonnet, Quentin Alias, Julien Ognard, Olivier Naggara, Maeva Kyheng, Bertrand Lapergue, Jildaz Caroff","doi":"10.1136/jnis-2024-021491","DOIUrl":"10.1136/jnis-2024-021491","url":null,"abstract":"<p><strong>Background: </strong>Retrospective studies suggest the superiority of first-line contact aspiration (CA) thrombectomy over stent-retriever (SR) in basilar artery occlusions (BAO). We aimed to investigate the impact of first-line mechanical thrombectomy per the occlusion level, considering differences in stroke etiology prevalence between proximal and distal BAO.</p><p><strong>Methods: </strong>A retrospective, multicentric analysis of the Endovascular Treatment in Ischemic Stroke Registry (ETIS) included consecutive BAO patients treated from January 2016 to May 2022. Patients were categorized into SR (±aspiration) and CA alone groups. Occlusion levels were determined through digital subtraction angiography. Favorable clinical outcome was defined as 90-day modified Rankin Scale (mRS) 0-3.</p><p><strong>Results: </strong>A total of 380 patients were analyzed (251 CA alone, 129 SR±aspiration). Globally, first-line SR showed lower recanalization rates (89.1% vs 94.8%, OR=0.29, 95% CI 0.16 to 0.53; p<0.001) and worse clinical outcomes (mRS 0-3: 46.0% vs 52.2%, OR=0.62, 95% CI 0.44 to 0.87; p=0.006) compared with CA. In proximal occlusions, SR was significantly associated with poorer clinical outcomes (mRS 0-3: 20.9% vs 37.1%; OR=0.40, 95% CI 0.19 to 0.83; p=0.014) despite similar recanalization rates. Conversely, in distal occlusions there was no difference in clinical outcomes although recanalization rates were higher with CA (modified Thrombolysis in Cerebral Infarction score (mTICI 2b/3): 97.7% vs 91.7%; OR=0.17, 95% CI 0.05 to 0.66; p=0.01).</p><p><strong>Conclusions: </strong>In our BAO population, CA demonstrated better angiographic outcomes in middle and distal occlusions and better clinical outcomes in proximal occlusions. This translated into better angiographic and clinical results in the global study population. Clinical results were particularly influenced by the negative impact of SR on 90-day mRS, independently of recanalization rates in proximal BAO.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":"346-353"},"PeriodicalIF":4.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140305833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to 'Critical appraisal of Gelfoam embolization technique in retinoblastoma treatment: a call for caution and further investigation'.","authors":"Fouad Georges Akkari, Guillaume Saliou, Bruno Bartolini","doi":"10.1136/jnis-2024-022989","DOIUrl":"10.1136/jnis-2024-022989","url":null,"abstract":"","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":"445"},"PeriodicalIF":4.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MR-VWI concentric ring sign: a potential imaging feature of internal carotid artery pseudo occlusion and predictive value for successful recanalization.","authors":"Wenxuan Lu, Wenhui Zhang, Dongxu Zhao, Yilin Zhang, Huili Gao, Tianxiao Li, Zhaoshuo Li","doi":"10.1136/jnis-2025-023051","DOIUrl":"https://doi.org/10.1136/jnis-2025-023051","url":null,"abstract":"<p><strong>Background: </strong>Predicting the success of endovascular recanalization in non-acute internal carotid artery occlusion (NICAO) remains a challenge.</p><p><strong>Objective: </strong>To examine the hypothesis that the concentric ring sign observed on high-resolution magnetic resonance vessel wall imaging (MR-VWI) could serve as a potential imaging biomarker to improve the accuracy of predicting recanalization success and guide treatment decisions.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on patients with NICAO who underwent endovascular treatment at our institution between January 2020 and December 2023. Baseline data and details of preoperative digital subtraction angiography (DSA) and MR-VWI, perioperative complications, technical success rates, and follow-up outcomes were collected. A nomogram model was constructed via stepwise regression based on statistically significant variables to predict recanalization success.</p><p><strong>Results: </strong>In total, 63 cases were included in this study. The overall recanalization success rate was 82.5% (52/63), and the periprocedural complication rate was 12.7% (8/63). Stepwise regression identified key predictors, including tapered stumps, occlusion segments ≤4, short occlusion duration, and the C2 concentric ring sign (P<0.05). The resulting nomogram demonstrated excellent predictive capabilities for successful recanalization (area under the curve 0.971).</p><p><strong>Conclusion: </strong>The predictive model, integrating MR-VWI and digital subtraction angiography features-including the newly identified 'concentric ring sign'-exhibited excellent predictive performance and clinical usefulness, providing a reliable tool for preoperative evaluation and treatment planning in patients with NICAO.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thrombogenicity assessment of surface-modified flow diverters: the impact of different surface modification strategies on thrombin generation in an acute <i>in vitro</i> test.","authors":"Guillaume Charbonnier, Nicole M Cancelliere, Alice B Brochu, Allison M Marley, Vitor M Pereira","doi":"10.1136/jnis-2024-022737","DOIUrl":"https://doi.org/10.1136/jnis-2024-022737","url":null,"abstract":"<p><strong>Background: </strong>New generation flow-diverting stents have benefited from recent technological advances to reduce their thrombogenicity. This in vitro study is the first of its kind to compare multiple surface modified flow diverters with their bare metal counterparts.</p><p><strong>Methods: </strong>A thrombin generation assay (TGA) was used to compare thrombin generation resulting from different stent types with glass beads (positive control) and plasma (negative control). Ten different stent types were studied, including a next-generation implant, Surpass Elite, with two different surface modifications. A thrombogram was generated from each of the 10 sample types, from which peak thrombin generation and time to peak (TTP) were obtained.</p><p><strong>Results: </strong>Compared with the positive control and their bare metal counterparts, lower peak thrombin and longer TTP were obtained with most of the surface modified devices tested. Only the stent with an active heparin drug coating demonstrated lower peak thrombin and TTP than the negative control plasma.</p><p><strong>Conclusion: </strong>Generally, surface modification resulted in lower thrombogenicity, as assessed by peak thrombin concentration and TTP, when compared with the unmodified version of the device. The device with an active heparin drug coating was significantly different from other surface modifications and plasma with respect to peak thrombin and TTP, though the implications of this should be investigated through future <i>in vitro</i> and <i>in vivo</i> studies.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of stent use on vasospasm occurrence after subarachnoid hemorrhage: a propensity score matching analysis.","authors":"Hyeong Jin Lee, Sunghan Kim, Seon Woong Choi, Hoon Kim, Seong-Rim Kim, Ik Seong Park","doi":"10.1136/jnis-2025-023112","DOIUrl":"https://doi.org/10.1136/jnis-2025-023112","url":null,"abstract":"<p><strong>Objective: </strong>We hypothesized that stents in stent-assisted coil embolization during endovascular treatment (EVT) may reduce the risk of symptomatic vasospasm following aneurysmal subarachnoid hemorrhage (aSAH) and its treatment. This study aimed to evaluate the impact of stent placement on the occurrence of symptomatic vasospasm, identify the associated risk factors, and analyze symptomatic vasospasm occurrence according to treatment modality and aneurysm location.</p><p><strong>Methods: </strong>We retrospectively analyzed 546 aSAH patients treated from 2013 to 2022. The primary outcome was symptomatic vasospasm occurrence. Potential risk factors for symptomatic vasospasm were evaluated using multivariate logistic regression. Propensity score matching was used to assess the impact of stent use during EVT, treatment modality (coiling vs clipping), and aneurysm location (anterior vs posterior circulation) on symptomatic vasospasm occurrence.</p><p><strong>Results: </strong>Multivariate analysis identified younger age (OR 0.954, 95% CI 0.934 to 0.974, P<0.001), external ventricular drainage (EVD) placement (OR 2.470, 95% CI 1.404 to 4.346, P=0.002), higher white blood cell (WBC) count (OR 1.057, 95% CI 1.006 to 1.109, P=0.027), and higher modified Fisher scale score (OR 4.303, 95% CI 1.725 to 10.736, P=0.002) as significant risk factors. Propensity score matched analysis revealed that stent use during EVT significantly reduced the risk of symptomatic vasospasm (OR 0.413, 95% CI 0.176 to 0.970, P=0.042); however, treatment modality and aneurysm location showed no significant influence.</p><p><strong>Conclusions: </strong>We found that stent placement during EVT significantly reduced the occurrence of symptomatic vasospasm after aSAH. Additional risk factors included younger age, EVD placement, higher WBC count, and higher modified Fisher scale score. Further studies are warranted to validate these findings and explore their implications for clinical practice.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}