Journal of NeuroInterventional Surgery最新文献

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Practical arterial atlas of the pig for neurointerventional simulation. 用于神经介入模拟的猪实用动脉图谱。
IF 4.3 1区 医学
Journal of NeuroInterventional Surgery Pub Date : 2025-10-05 DOI: 10.1136/jnis-2025-024149
Mirella Merlette, Aymeric Rouchaud, Charbel Mounayer, Eimad Shotar, Chrysanthi Papagiannaki, Claude Couquet, Géraud Forestier, Frederic Crampon, Elisabeth Garrido, Emmanuel Gerardin, Frédéric Clarençon, Julien Burel
{"title":"Practical arterial atlas of the pig for neurointerventional simulation.","authors":"Mirella Merlette, Aymeric Rouchaud, Charbel Mounayer, Eimad Shotar, Chrysanthi Papagiannaki, Claude Couquet, Géraud Forestier, Frederic Crampon, Elisabeth Garrido, Emmanuel Gerardin, Frédéric Clarençon, Julien Burel","doi":"10.1136/jnis-2025-024149","DOIUrl":"https://doi.org/10.1136/jnis-2025-024149","url":null,"abstract":"<p><p>This article presents a practical anatomical atlas of the arterial neuroanatomy of the swine, intended for training and research in neurointerventional surgery. The swine is a well-established large-animal model due to its anatomical similarities with humans. The atlas begins with a concise overview of the femoroiliac arterial tree and the aorta, followed by a focused description of the common carotid and subclavian arteries, and finally the cephalic arteries-both intracranial and extracranial. Average lengths and diameters of the cephalic arterial segments in pigs (30-80 kg) were retrospectively determined from 3D rotational angiographies acquired in five animals previously used in experimental studies. Anatomical descriptions are supported by schematic diagrams and volume rendering reconstructions. This reference tool is designed to standardize anatomical understanding, enhance the effective use of the pig model, and minimize animal distress in experimental procedures. It serves as a valuable resource for practitioners in neurointerventional surgery.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Supply cost and outcome comparison of nBCA, Onyx, and coils for middle meningeal artery embolizations: a single-center retrospective analysis. nBCA、Onyx和线圈用于脑膜中动脉栓塞的供应成本和结果比较:单中心回顾性分析。
IF 4.3 1区 医学
Journal of NeuroInterventional Surgery Pub Date : 2025-10-05 DOI: 10.1136/jnis-2025-024003
Kiernan Joseph Gunn, Eric Sleasman, Sajal Medha K Akkipeddi, Prasanth Romiyo, Eric Davis, Pablo Valdes Barrera, Santiago Mendoza-Ayus, Vidhya Dhar, Derrek Schartz, Vincent N Nguyen, Tarun Bhalla, Thomas Mattingly, Matthew T Bender
{"title":"Supply cost and outcome comparison of nBCA, Onyx, and coils for middle meningeal artery embolizations: a single-center retrospective analysis.","authors":"Kiernan Joseph Gunn, Eric Sleasman, Sajal Medha K Akkipeddi, Prasanth Romiyo, Eric Davis, Pablo Valdes Barrera, Santiago Mendoza-Ayus, Vidhya Dhar, Derrek Schartz, Vincent N Nguyen, Tarun Bhalla, Thomas Mattingly, Matthew T Bender","doi":"10.1136/jnis-2025-024003","DOIUrl":"https://doi.org/10.1136/jnis-2025-024003","url":null,"abstract":"<p><strong>Background: </strong>Middle meningeal artery (MMA) embolization is increasingly utilized in the treatment of chronic subdural hematoma (cSDH); however, supply cost variation between embolization agents remains unclear. We hypothesized that nBCA might be associated with lower costs, given the ability to use a single vial and treat multiple pedicles.</p><p><strong>Objective: </strong>To compare the supply costs of MMA embolizations using ethylene vinyl-alcohol copolymer-based Onyx (Onyx), n-butyl cyanoacrylate-based TRUFILL (nBCA), and/or coils.</p><p><strong>Methods: </strong>This retrospective study analyzed 100 consecutive MMA embolizations performed at a single institution before March 2025. The supplies (including catheters and embolic agents) used in each embolization, along with procedure time, laterality, and number of pedicles embolized, were documented. Radiographic and clinical patient outcomes were evaluated.</p><p><strong>Results: </strong>Of the 100 procedures: 63 used nBCA, 26 Onyx, 2 coils, 2 nBCA and coils, and 7 Onyx and coils. Supply costs ranged from approximately $5000 to $18 000. Onyx was significantly less expensive than nBCA in supply cost per patient ($7910 vs $10 241; P<0.0001), cost per side ($6467 vs $7857; P=0.010), and cost per pedicle ($4375 vs $5369; P=0.012). Mean cost per patient was highest for nBCA and coils ($13 541 ± $1331), Onyx and coils ($12 364 ± $3259), and coils alone ($11 058 ± $1144). There were no significant differences in short-term complications (stroke, seizure, cranial nerve palsy, retreatment, hospital readmissions; P>0.05), functional outcomes (modified Rankin Scale; P=0.813), or complete cSDH resolution (P=0.149) between embolic techniques.</p><p><strong>Conclusions: </strong>There is significant variation in supply cost associated with different MMA embolization techniques. In our institutional experience, Onyx was associated with the lowest supply cost per patient, hemisphere, and pedicle. Complication rates and functional status did not significantly differ across techniques.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Balloon-assisted retrieval of detached microwire tip during mechanical thrombectomy. 机械取栓时球囊辅助取离体微丝尖端。
IF 4.3 1区 医学
Journal of NeuroInterventional Surgery Pub Date : 2025-10-02 DOI: 10.1136/jnis-2025-024154
Ariharan K, Somasree Manna, Rasmiranjan Padhi, Vignesh S
{"title":"Balloon-assisted retrieval of detached microwire tip during mechanical thrombectomy.","authors":"Ariharan K, Somasree Manna, Rasmiranjan Padhi, Vignesh S","doi":"10.1136/jnis-2025-024154","DOIUrl":"https://doi.org/10.1136/jnis-2025-024154","url":null,"abstract":"<p><p>Mechanical thrombectomy is the standard of care for acute ischemic stroke due to large vessel occlusion.1 The reported intraprocedural complication rate is approximately 8%, including emboli to new territory, perforations and dissections.2 3 Rarely, technical device failures such as microwire tip detachment can occur during neurointerventional procedures. Previously reported cases of guidewire detachment have utilized microsnares or stent retrievers for retrieval.4 5 In this technical video 1, we describe one such complication of microwire tip detachment and its successful retrieval. In our case, the proximal end of the detached microwire was initially pinned within the aspiration catheter using a compliant balloon and retrieved up to the cervical segment of the internal carotid artery (ICA), where the detached tip slipped out of the aspiration catheter. From the cervical ICA, the detached tip was successfully retrieved using a stent retriever. This balloon-anchored retrieval (BAR) technique may also be useful in managing a detached microcatheter tip.neurintsurg;jnis-2025-024154v1/V1F1V1Video 1.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Broadway 8 system: a multicenter early evaluation of safety, performance, and clinical outcomes in mechanical thrombectomy. 百老汇8系统:多中心早期评估机械取栓的安全性、性能和临床结果。
IF 4.3 1区 医学
Journal of NeuroInterventional Surgery Pub Date : 2025-10-02 DOI: 10.1136/jnis-2025-024067
Rime Ezzeldin, Osman Mir, Adam Delora, SoHyun Boo, Santiago Ortega-Gutierrez, Jaydevsinh Dolia, Diogo C Haussen, Clemens Maria Schirmer, Fadi Alsaiegh, Justin Mascitelli, Ameer E Hassan, Muhammad Waqas Khan, Jan-Karl Burkhardt, Omar Malik, Daniel Diehl, Mario Zanaty, Ahmed Aljuboori, Samantha Miller, Visish M Srinivasan, Kyle Scott, Zuhair Ali, Mohamad Ezzeldin
{"title":"Broadway 8 system: a multicenter early evaluation of safety, performance, and clinical outcomes in mechanical thrombectomy.","authors":"Rime Ezzeldin, Osman Mir, Adam Delora, SoHyun Boo, Santiago Ortega-Gutierrez, Jaydevsinh Dolia, Diogo C Haussen, Clemens Maria Schirmer, Fadi Alsaiegh, Justin Mascitelli, Ameer E Hassan, Muhammad Waqas Khan, Jan-Karl Burkhardt, Omar Malik, Daniel Diehl, Mario Zanaty, Ahmed Aljuboori, Samantha Miller, Visish M Srinivasan, Kyle Scott, Zuhair Ali, Mohamad Ezzeldin","doi":"10.1136/jnis-2025-024067","DOIUrl":"https://doi.org/10.1136/jnis-2025-024067","url":null,"abstract":"<p><strong>Background: </strong>Large-bore aspiration catheters are integral to mechanical thrombectomy (MT) for large vessel occlusions (LVOs), offering potential for improved first pass success and faster recanalization.</p><p><strong>Objective: </strong>To assess the clinical performance, efficacy, and safety profile of the Broadway 8 system as a primary aspiration device in MT of LVOs.</p><p><strong>Methods: </strong>This is a multicenter observational study conducted across 8 US comprehensive stroke centers. Efficacy outcomes included first pass effect (FPE), defined as a single-pass modified Treatment In Cerebral Infarction (mTICI) score ≥2c, and successful reperfusion (final mTICI ≥2b). Safety outcomes included device-related complications, symptomatic intracranial hemorrhage (sICH), and inpatient mortality. Functional outcomes included modified Rankin Scale (mRS) at discharge and delta National Institutes of Health Stroke Scale (NIHSS) score. Logistic regression was used to assess predictors of thrombus access and intermediate catheter use.</p><p><strong>Results: </strong>49 patients were included. The Broadway 8 system reached the thrombus in 44 (89.8%). Median puncture-to-thrombus and puncture-to-reperfusion times were 11 min (IQR 9-18) and 20 min (14-31), respectively. FPE was achieved in 20 (40.8%). Successful reperfusion was achieved in 46/49 (93.8%), with 35 (71.4%) using Broadway 8. sICH occurred in 2 patients (4.1%). Median mRS at discharge was 3.0 (IQR 1.0-4.0); delta NIHSS was 8 (IQR 5-12). Regression analysis showed faster reperfusion when Broadway 8 was used without an intermediate catheter.</p><p><strong>Conclusion: </strong>The Broadway 8 system appears to be a safe and effective frontline aspiration device, demonstrating a safety and efficacy profile comparable to other large-bore aspiration systems that incorporate delivery-assist technology.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety and efficacy of selective and superselective intra-arterial cerebral infusion with blood-brain barrier disruption for glioma: a systematic review and meta-analysis. 选择性和超选择性脑动脉输注破坏血脑屏障治疗胶质瘤的安全性和有效性:一项系统综述和荟萃分析。
IF 4.3 1区 医学
Journal of NeuroInterventional Surgery Pub Date : 2025-10-02 DOI: 10.1136/jnis-2025-024057
Christian Ferreira, Márcio Yuri Ferreira, Leonardo Januario Campos Cardoso, João Paulo Liute Scarramal, Alleh Nogueira, Tamika Wong, Sanskruti Bokil, Faith Singh, Sara Massimo, Olivia Albers, Netanel Ben-Shalom, Randy D'Amico, David Langer, John Boockvar, Yafell Serulle
{"title":"Safety and efficacy of selective and superselective intra-arterial cerebral infusion with blood-brain barrier disruption for glioma: a systematic review and meta-analysis.","authors":"Christian Ferreira, Márcio Yuri Ferreira, Leonardo Januario Campos Cardoso, João Paulo Liute Scarramal, Alleh Nogueira, Tamika Wong, Sanskruti Bokil, Faith Singh, Sara Massimo, Olivia Albers, Netanel Ben-Shalom, Randy D'Amico, David Langer, John Boockvar, Yafell Serulle","doi":"10.1136/jnis-2025-024057","DOIUrl":"https://doi.org/10.1136/jnis-2025-024057","url":null,"abstract":"<p><strong>Background: </strong>Selective and superselective intra-arterial cerebral infusion (SIACI/SSIACI) delivers chemotherapy directly to tumor-supplying arteries, achieving high local drug levels with reduced systemic toxicity. Often combined with blood-brain barrier disruption (BBBd) to enhance penetration, these methods have been widely studied, yet a comprehensive evidence synthesis is lacking. This study systematically assesses the safety and efficacy of intra-arterial chemotherapy with BBBd for glioma treatment.</p><p><strong>Methods: </strong>We searched PubMed, Embase, and Web of Science for studies on SIACI with BBBd in glioma patients. Safety outcomes included rates of cases with complications, procedure-related complications (major/minor), stroke, intracranial and intratumoral hemorrhage, and mortality. Efficacy was based on tumor response (complete, partial, stable disease, progression). A subanalysis of SSIACI-only cases was also conducted.</p><p><strong>Results: </strong>Nine studies with 230 glioma patients were included. The pooled rate of cases with complications was 27.1% (95% CI 19.8% to 35.7%), with procedure-related complications occurring in 15.4% (95% CI 6.1% to 24.6%). Major and minor complication rates were 4.3% (95% CI 0.9% to 7.7%) and 9.7% (95% CI 1.0% to 18.7%), respectively. Stroke, intracranial hemorrhage, and intratumoral hemorrhage occurred in 3.1% (95% CI 0% to 6.1%), 0.5% (95% CI 0% to 3.2%), and 0.04% (95% CI 0% to 3%), respectively, with no procedure-related deaths reported. Pooled response rates were 10.4% complete (95% CI 0% to 21.5%), 24.2% partial (95% CI 14.3% to 34.1%), 38.2% stable disease (95% CI 21.5% to 54.9%), and 39.3% progression (95% CI 14.8% to 63.8%). Subanalysis of superselective infusions yielded comparable outcomes to the overall cohort.</p><p><strong>Conclusion: </strong>The findings indicate that SIACI/SSIACI chemotherapy following BBBd is a feasible and safe approach for glioma treatment, demonstrating a favorable procedural risk profile and preliminary signs of efficacy. Further studies are warranted to validate these results and refine procedural protocols.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a rabbit model of eccentric carotid atherosclerotic stenosis via localized cryoinjury. 局部冷冻损伤制备偏心颈动脉粥样硬化性狭窄兔模型。
IF 4.3 1区 医学
Journal of NeuroInterventional Surgery Pub Date : 2025-09-27 DOI: 10.1136/jnis-2025-023837
Yingkun He, Shikai Li, Yanyan He, Wenli Zhao, Yao Liu, Qianhao Ding, Yang Liu, Chenqing Li, Yukuan Pang, Zhengpeng Zhu, Yonghong Ding, Ferdinand Hui, Jia Liang, Tianxiao Li
{"title":"Development of a rabbit model of eccentric carotid atherosclerotic stenosis via localized cryoinjury.","authors":"Yingkun He, Shikai Li, Yanyan He, Wenli Zhao, Yao Liu, Qianhao Ding, Yang Liu, Chenqing Li, Yukuan Pang, Zhengpeng Zhu, Yonghong Ding, Ferdinand Hui, Jia Liang, Tianxiao Li","doi":"10.1136/jnis-2025-023837","DOIUrl":"https://doi.org/10.1136/jnis-2025-023837","url":null,"abstract":"<p><strong>Background: </strong>The eccentric stenosis morphology in patients with intracranial atherosclerotic stenosis (ICAS) has a critical impact on the efficacy of endovascular treatment. This study aimed to establish a rabbit model of eccentric carotid atherosclerotic stenosis that mimics the pathophysiological and morphological characteristics of eccentric plaques in humans.</p><p><strong>Methods: </strong>Rabbits received localized cryoinjury of the right carotid artery after 2 weeks of a high fat, high cholesterol diet, followed by an additional 8 weeks on the same diet. On the experimental endpoint, comprehensive analyses of the model's pathological changes were conducted using serum lipid analysis, DSA, optical coherence tomography (OCT), histopathological analysis, and immunohistochemistry.</p><p><strong>Results: </strong>The high fat, high cholesterol diet significantly elevated serum lipid levels in rabbits. Hematoxylin and eosin staining results at 24 hours postoperatively revealed focal intimal damage induced by 5 s of cryoinjury. After localized cryoinjury and high fat, high cholesterol diet feeding, DSA results demonstrated significant carotid stenosis, with a stenosis degree of 47±5% and a length of approximately 9 mm. OCT images revealed eccentric fibrous plaque formation at the stenotic site. Morphological analysis of the plaque samples demonstrated a plaque eccentricity index of 0.66±0.05 and a plaque burden of 60.68±7.41%. Histopathological analysis showed that atherosclerotic lesions developed in all rabbits of the model group. Among them, three rabbits had intermediate lesions, one rabbit had atheroma, and eight rabbits had fibroatheroma.</p><p><strong>Conclusions: </strong>This study successfully established a rabbit model of eccentric carotid atherosclerotic stenosis, providing a novel experimental platform for transformation research of neurointerventional devices.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness and outcomes of endovascular embolization on arteriovenous malformations with aneurysms: a nationwide multicenter prospective registry study. 血管内栓塞治疗动静脉畸形伴动脉瘤的疗效和结果:一项全国多中心前瞻性登记研究。
IF 4.3 1区 医学
Journal of NeuroInterventional Surgery Pub Date : 2025-09-27 DOI: 10.1136/jnis-2025-024007
Chengzhuo Wang, Heze Han, Li Ma, Ruinan Li, Zhipeng Li, Haibin Zhang, Kexin Yuan, Anqi Li, Qinghui Zhu, Yongenbo Su, Dezhi Gao, Hengwei Jin, Youxiang Li, Shibin Sun, Yuanli Zhao, Yu Chen, Xiaolin Chen, Jizong Zhao
{"title":"Effectiveness and outcomes of endovascular embolization on arteriovenous malformations with aneurysms: a nationwide multicenter prospective registry study.","authors":"Chengzhuo Wang, Heze Han, Li Ma, Ruinan Li, Zhipeng Li, Haibin Zhang, Kexin Yuan, Anqi Li, Qinghui Zhu, Yongenbo Su, Dezhi Gao, Hengwei Jin, Youxiang Li, Shibin Sun, Yuanli Zhao, Yu Chen, Xiaolin Chen, Jizong Zhao","doi":"10.1136/jnis-2025-024007","DOIUrl":"https://doi.org/10.1136/jnis-2025-024007","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to evaluate the long-term outcomes of cerebral arteriovenous malformations (AVMs) with associated aneurysms in patients who underwent exclusive endovascular embolization.</p><p><strong>Methods: </strong>Patients with aneurysmal AVMs were identified from China's nationwide MATCH registry. Propensity score matching balanced baseline differences between embolization and conservative management groups. The primary outcome was long-term hemorrhagic stroke or death; secondary outcomes included obliteration rate and neurological status. Subgroup and sensitivity analyses using various designs assessed the robustness of the results.</p><p><strong>Results: </strong>In the MATCH study, 230 patients with AVMs and associated aneurysms received embolization or conservative treatment. After screening, 83 patients received conservative management and 108 underwent embolization; 64 matched pairs were analyzed after propensity score matching. The embolization group had a mean follow-up of 6.88 years, with a post-procedure rupture risk of 2.75% per patient-year and a complete obliteration rate of 21.88%. Embolization was associated with a lower rate of hemorrhagic stroke or death (absolute risk reduction -3.50% per patient-year; HR 0.50) and a higher obliteration rate compared with conservative management. Neurological outcomes were similar between the two groups. Stratified analysis showed that curative and targeted embolization significantly reduced hemorrhagic stroke whereas palliative embolization did not. Subgroup and sensitivity analyses confirmed these trends, although the statistical power varied.</p><p><strong>Conclusion: </strong>This study suggests that embolization may reduce the risk of long-term hemorrhagic stroke or death in patients with aneurysmal AVMs. Curative and targeted approaches showed protective effects while palliative embolization had limited benefits.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subclavian loop catheterization technique (SLOT): novel transradial salvage technique for challenging vertebral artery ostial stenosis. 锁骨下环形置管技术(SLOT):一种新的经桡骨打捞技术,用于挑战椎动脉口狭窄。
IF 4.3 1区 医学
Journal of NeuroInterventional Surgery Pub Date : 2025-09-27 DOI: 10.1136/jnis-2025-023938
Meng Du, Dayong Qi, Jihu Zhao, Si Zhao Tang, Deyuan Zhu, Yibin Fang
{"title":"Subclavian loop catheterization technique (SLOT): novel transradial salvage technique for challenging vertebral artery ostial stenosis.","authors":"Meng Du, Dayong Qi, Jihu Zhao, Si Zhao Tang, Deyuan Zhu, Yibin Fang","doi":"10.1136/jnis-2025-023938","DOIUrl":"https://doi.org/10.1136/jnis-2025-023938","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy and safety of the subclavian loop catheter technique for endovascular stenting of vertebral artery ostial stenosis (VAOS).</p><p><strong>Methods: </strong>We retrospectively reviewed all patients who underwent vertebral artery stenting between January 2022 and April 2025. The analysis included only those in whom standard transradial access (TRA) failed and the subclavian artery loop technique was used. Outcomes assessed included vascular access and surgical complications, postoperative modified Rankin Scale (mRS) scores, and in-stent restenosis on follow-up.</p><p><strong>Results: </strong>Of 134 vertebral artery stenting procedures, 12 cases in which standard TRA failed were successfully completed using the subclavian loop catheter technique. Patients were aged 18-80 years, and VAOS was more frequent on the right side (n=11/12). Mean preoperative stenosis was 79%, reduced to 7.5% after stenting. No major periprocedural complications occurred. Median time from catheter loop formation to stent deployment was 33 min. Median follow-up was 3 months, during which 67% of patients were assessed and no in-stent restenosis was detected.</p><p><strong>Conclusions: </strong>The subclavian loop catheter technique via TRA was a safe, effective, and feasible option for VAOS stenting when conventional radial or transfemoral access was limited by vascular anatomy. The technique provided stable access, enabled precise stent deployment, and demonstrated a favorable safety profile in this series.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145181994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety and efficacy of stent-assisted coiling with the pEGASUS-HPC stent in wide-necked intracranial aneurysms: a multicenter retrospective analysis. pEGASUS-HPC支架辅助盘绕治疗颅内宽颈动脉瘤的安全性和有效性:一项多中心回顾性分析
IF 4.3 1区 医学
Journal of NeuroInterventional Surgery Pub Date : 2025-09-24 DOI: 10.1136/jnis-2025-023946
Mohammad Almohammad, Ali Khanafer, Mete Dadak, Christopher Nimsky, Alexander Grote, Bayan Alhaj Moustafa, Islam El Malky, Lisa Hekers, Abdallah Aburub, Zakarya Ali, Mariana Gurschi, Julia Korthäuer, Stephan Felber, Hans Henkes, André Kemmling
{"title":"Safety and efficacy of stent-assisted coiling with the pEGASUS-HPC stent in wide-necked intracranial aneurysms: a multicenter retrospective analysis.","authors":"Mohammad Almohammad, Ali Khanafer, Mete Dadak, Christopher Nimsky, Alexander Grote, Bayan Alhaj Moustafa, Islam El Malky, Lisa Hekers, Abdallah Aburub, Zakarya Ali, Mariana Gurschi, Julia Korthäuer, Stephan Felber, Hans Henkes, André Kemmling","doi":"10.1136/jnis-2025-023946","DOIUrl":"https://doi.org/10.1136/jnis-2025-023946","url":null,"abstract":"<p><strong>Background: </strong>Stent-assisted coiling is widely used for the treatment of wide-necked intracranial aneurysms. The pEGASUS-HPC stent features a hydrophilic polymer coating designed to reduce thrombogenicity, potentially improving safety, particularly in ruptured aneurysms and complex configurations.</p><p><strong>Objective: </strong>To evaluate the safety, efficacy, and technical feasibility of stent-assisted coiling using the pEGASUS-HPC stent in the treatment of wide-necked intracranial aneurysms.</p><p><strong>Methods: </strong>We retrospectively analyzed 223 patients with 251 wide-necked aneurysms treated at six centers between July 2021 and March 2025. Primary endpoints included angiographic occlusion (modified Raymond-Roy classification, MRRC), periprocedural complications, and clinical outcome (modified Rankin Scale, mRS) at discharge and follow-up. Subgroup analysis was performed for ruptured aneurysms and bifurcation cases requiring Y-stenting.</p><p><strong>Results: </strong>Stent deployment and coiling were technically successful in all cases. Immediate complete occlusion (MRRC I) was achieved in 92.4% of aneurysms, increasing to 96.8% at follow-up. The overall retreatment rate was 2.2%. Periprocedural complications occurred in 1.6% of cases, consisting of two minor perforations in unruptured aneurysms, both managed without clinical consequences. In ruptured cases a favorable outcome (mRS ≤2) was observed in 71.1%, with mortality confined to Hunt and Hess grade V or basilar artery aneurysms. Y-stenting was performed in 15.9% of cases without technical failure. No perforations occurred in ruptured cases.</p><p><strong>Conclusion: </strong>Stent-assisted coiling with the pEGASUS-HPC stent appears technically feasible and effective for wide-necked aneurysms, including acute ruptured cases and those requiring Y-stenting, with high occlusion rates and low complication rates.</p>","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correpondence on 'Updated classification with spinal dysraphism and treatment outcomes of arteriovenous shunts below conus: a retrospective cohort study' by Yuxiang et al. Yuxiang等人的“脊柱发育异常的最新分类和椎体下动静脉分流的治疗结果:一项回顾性队列研究”的对应。
IF 4.3 1区 医学
Journal of NeuroInterventional Surgery Pub Date : 2025-09-24 DOI: 10.1136/jnis-2024-022895
Xuefan Zeng
{"title":"Correpondence on 'Updated classification with spinal dysraphism and treatment outcomes of arteriovenous shunts below conus: a retrospective cohort study' by Yuxiang <i>et al</i>.","authors":"Xuefan Zeng","doi":"10.1136/jnis-2024-022895","DOIUrl":"10.1136/jnis-2024-022895","url":null,"abstract":"","PeriodicalId":16411,"journal":{"name":"Journal of NeuroInterventional Surgery","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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