R. Mohamed, E. Fawzy, R. Shehab, M. Abdel-Salam, Rawheya A. Salah El Din, Hesham M. Abd El Fatah
{"title":"Production, Characterization, and Cytotoxicity Effects of Silver Nanoparticles from Brown Alga (Cystoseira myrica)","authors":"R. Mohamed, E. Fawzy, R. Shehab, M. Abdel-Salam, Rawheya A. Salah El Din, Hesham M. Abd El Fatah","doi":"10.1155/2022/6469090","DOIUrl":"https://doi.org/10.1155/2022/6469090","url":null,"abstract":"A green, eco-friendly approach to biosynthesizing silver nanoparticles has been reported for marine macroalga (Cystoseira myrica) extract as a reducing agent. Different pH and temperature impact the green synthesis of silver nanoparticles suggesting that the synthesis depends greatly on pH and temperature. The structure and characters of synthesized nanoparticles were confirmed using HR-TEM, DLS, XRD, and FTIR. Cytotoxicity was indicated using provided cell lines of breast carcinoma cells (MCF-7) and human hepatocellular carcinoma cells (HepG2). Shape of silver nanoparticles at pH 9 and 75°C for 30 min was found to be suitable for the biosynthesis process and the AgNPs exhibited a characteristic absorption peak at 434 nm. High Resolution Electron Microscope Transmission reported polydisperse and spherical shapes ranging from 8 to 15 nm. High attractive and repulsive forces between each nanoparticle were recorded with an average zeta-potential value of approximately −29.3 mV. The X-ray diffraction study revealed the crystalline structure of silver nanoparticles. FTIR has shown the bioreduction of silver ions to silver nanoparticles through biomolecules found in algal extract. Silver nanoparticles have been found to have anticancer activity. The cytotoxicity assay was studied against MCF-7 and HepG2 at various concentrations (100, 50, 25, 12.5, 6.25, 3.125, 1.56, 0.78, 0.39, 0.2, and 0.1 μg/mL). By increasing the concentration of AgNPs from 0.1 to 100 μg/mL, the maximum percentage of viability against MCF-7 and HepG2 cell line decreased from 94.55 ± 7.55 to 19.879 ± 0.503 and from 78.56 ± 11.36 to 25.81 ± 2.66 after time exposure, respectively.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":"25 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81391700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sareh Bagheri-Josheghani, B. Bakhshi, Shahin Najar-Peerayeh
{"title":"The Influence of Nanoparticle on Vaccine Responses against Bacterial Infection","authors":"Sareh Bagheri-Josheghani, B. Bakhshi, Shahin Najar-Peerayeh","doi":"10.1155/2022/6856982","DOIUrl":"https://doi.org/10.1155/2022/6856982","url":null,"abstract":"Nowadays, nanovaccine is considered as an evolving method in the field of vaccination to induce immunity in the human body against various diseases, including bacterial or viral diseases as well as virulent tumors. Nanovaccines are more efficient than traditional vaccines since they could potentially induce both humoral and cellular immune reactions. Various studies have shown that nanoparticles with multiple compounds have been designed as delivery systems or as adjuvants for vaccines. Nanoparticles could function as a drug delivery tool, as an adjuvant to promote antigen processing, and as an immune modulator to induce immune responses. These nanoparticles generate immune responses through activating immune cells as well as through the production of antibody responses. Design engineering of nanoparticles (NPs) used to produce nanovaccines to induce immunity in the human body needs comprehensive information about the ways they interact with the component of immune system. Challenges remain due to the lack of sufficient and comprehensive information about the nanoparticles' mode of action. Several studies have described the interactions between various classes of nanoparticles and the immune system in the field of prevention of bacterial infections. The results of some studies conducted in recent years on the interaction between nanoparticles and biosystems have considerably affected the methods used to design nanoparticles for medical applications. In this review, NPs’ characteristics influencing their interplay with the immune system were discussed in vivo. The information obtained could lead to the development of strategies for rationalizing the design of nanovaccines in order to achieve optimum induction of immune response.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":"28 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2022-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74326662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Cortés-Camargo, Angélica Jiménez-Rosales, P. E. Acuña-Avila
{"title":"Green Synthesis of Ag NPs Using Ustilago maydis as Reducing and Stabilizing Agent","authors":"S. Cortés-Camargo, Angélica Jiménez-Rosales, P. E. Acuña-Avila","doi":"10.1155/2022/2494882","DOIUrl":"https://doi.org/10.1155/2022/2494882","url":null,"abstract":"Ustilago maydis (UM) is a fungus that grows naturally on Zea mays; it reduces the corn yields, and thus, it represents huge economic loss; however, it can be used as an exotic food, and in the present work, it is successfully used as a reducing and stabilizing agent for the preparation of silver nanoparticles (Ag NPs) due to its content of amino acids and biosurfactants. The effects of the concentration of UM aqueous extract, pH, and sunlight on the particle size, surface plasmon resonance, stability, and morphology of Ag NPs obtained by green synthesis were evaluated. A green reduction was observed only in presence of UM, and colloidal Ag NPs were obtained with or without the presence of sunlight; nevertheless, continuous sunlight exposure greatly increased the reaction rate. Ag NPs tend to increase in size from 153 nm to 1400 nm at a higher pH and a greater amount of UM, and also, UM tends to stabilize the Ag NPs preventing their agglomeration according to measurement of zeta potential (−10.75 ± 0.84 mV) and SEM observation; furthermore, surface plasmon resonances were more intense between 400 and 480 nm of wavelength adding greater amount of UM. This study concludes that UM not only reduces AgNO3 but also acts as stabilizer of Ag NPs.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":"121 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72580365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Perspective Review on Thermal Conductivity of Hybrid Nanofluids and Their Application in Automobile Radiator Cooling","authors":"W. E. Ukueje, F. Abam, A. Obi","doi":"10.1155/2022/2187932","DOIUrl":"https://doi.org/10.1155/2022/2187932","url":null,"abstract":"Hybrid nanofluids developed with the fusion or suspension of two or more different nanoparticles in a mixture as a novel heat transfer fluid are currently of interest to researchers due to their proven better measured thermal conductivities. Several reviewed articles exist on the thermal conductivity of hybrid nanofluids, a vital property for which the heat transfer rate is directly dependent. This review aims to understand the current developments in hybrid nanofluids and their applications. An extensive literature survey was carried out of heuristic-based articles published in the last 15 years. The review reiterates topical research on the preparation methods and ways to improve the stability of readied fluid, thermophysical properties of mixture nanofluids, and some empirical correlations developed for estimating thermal conductivity. Hybrid nanofluid studies on heat transfer performance in automobile radiator cooling systems were also obtained and discussed. The review’s significant findings include the following: (1) hybrid nanofluids produce a noticeable thermal conductivity enhancement and a relatively higher heat transfer coefficient than mono nanofluids and regular liquids. Furthermore, through the uniform dispersion and stable suspension of nanoparticles in the host liquids, the maximum possible thermal augmentation can be obtained at the lowest possible concentrations (by <0.1% by volume). (2) An automobile radiator’s overall heat transfer accomplishment can thus be boosted by using a mixture of nanofluids as conventional coolants. Up-to-date literature results on the thermal conductivity enhancement of mixture fluids are also presented in this study. Nonetheless, some of the barriers and challenges acknowledged in this work must be addressed for its complete deployment in modern applications.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":"85 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2022-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90676234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Nguyen, Tinh Ngoc Tran, A. C. Ha, Phu Dai Huynh
{"title":"Impact of Deacetylation Degree on Properties of Chitosan for Formation of Electrosprayed Nanoparticles","authors":"H. Nguyen, Tinh Ngoc Tran, A. C. Ha, Phu Dai Huynh","doi":"10.1155/2022/2288892","DOIUrl":"https://doi.org/10.1155/2022/2288892","url":null,"abstract":"Biopolymer of natural origin as chitosan has been studied and applied widely in practice. In the pharmaceutical field, especially, chitosan nanoparticles have been researched for a variety of drug delivery systems. There are many factors influencing the success of the chitosan nanoparticle delivery system. Therein, the specific parameters to the physicochemical nature of chitosan greatly determine the efficiency of its drugs carrier. The degree of deacetylation (DD) of chitosan is one of those parameters. In this study, the influence of DD on chitosan properties was clarified to facilitate the preparation of nanoparticles by the electrospraying method. DD can affect the solubility, crystallinity, and surface tension of chitosan, but it cannot strongly impact the viscosity of chitosan solution as much as the molecular weight (Mv). From these results, M3 chitosan, owning a high DD of 86.70%, and crystalline index of 44%, was dissolved in acetic acid for the collection of electrosprayed nanoparticles. The M3 solution having low viscosity of under 50 mm2/s displayed the easy adjustment of the stable Taylor-cone droplet at the nozzle tip. Particularly, the M3 chitosan solution with a concentration of 1.5 wt.% in acetic acid of 90 wt.% concentration operated at the working condition of 12 kV voltage, a distance between the two electrodes of 10 cm created spherical particles with an average diameter of 338 nm, narrow size distribution. These chitosan nanoparticles can obtain the initial requirement for application as injectable drugs carrier.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":"31 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2022-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78791188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Owida, Jamal I. Al-Nabulsi, Nidal M. Turab, Nawal Louzi
{"title":"Nanotechnology Role Development for COVID-19 Pandemic Management","authors":"H. Owida, Jamal I. Al-Nabulsi, Nidal M. Turab, Nawal Louzi","doi":"10.1155/2022/1872933","DOIUrl":"https://doi.org/10.1155/2022/1872933","url":null,"abstract":"The global outbreak of coronavirus disease has sent an ominous message to the field of innovative and advanced technology research and development (COVID-19). To accomplish this, convectional technology and recent discoveries can be combined, or new research directions can be opened up using nanotechnology. Nanotechnology can be used to prevent, diagnose, and treat SARS-CoV-2 infection. As the pandemic spreads, a thorough examination of nanomaterials' role in pandemic response is highly desirable. According to this comprehensive review article, nanotechnology can be used to prevent, diagnose, and treat COVID-19. This research will be extremely useful during the COVID-19 outbreak in terms of developing rules for designing nanostructure materials to combat the outbreak.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":"20 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2022-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84237423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. T. Tran, H. V. Tran, H. Cao, T. H. Tran, C. D. Huynh
{"title":"Electrochemically Effective Surface Area of a Polyaniline Nanowire-Based Platinum Microelectrode and Development of an Electrochemical DNA Sensor","authors":"L. T. Tran, H. V. Tran, H. Cao, T. H. Tran, C. D. Huynh","doi":"10.1155/2022/8947080","DOIUrl":"https://doi.org/10.1155/2022/8947080","url":null,"abstract":"Electrochemical DNA sensors based on nanocomposite materials of polyaniline nanowires (PANi NWs) have been published in the literature. However, it is interesting that there are very few research studies related to the development of electrochemical DNA sensors based on PANi NWs individually. In this study, PANi NWs were synthesized site-specifically on a Pt microelectrode with only 0.785 mm2 area using an electropolymerization procedure. The electrosynthesis allows direct deposition of PANi NWs onto the Pt microelectrode in a rapid and cost-effective way. The good properties of PANi NWs including uniform size, uniform distribution throughout the Pt working electrode, and H2SO4 doping which improved the conductivity of the PANi material were obtained. Especially, the electrochemically effective surface area of the PANi NW-based Pt microelectrode determined in this work is nearly 19 times larger than that of the Pt working electrode. The PANi NW layer with large electrochemically effective surface area and high biocompatibility is consistent with the application in electrochemical DNA sensors. The fabricated DNA sensors show advantages such as simple fabrication, direct detection, high sensitivity (with the detection limit of 2.48 × 10−14 M), good specificity, and low sample volume requirement. This study also contributes to confirm the role of PANi NWs in DNA probe immobilization as well as in electrochemical signal transmission in the development of electrochemical DNA sensors.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":"33 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2022-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89538919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Olawale, O. Oladimeji, M. Ariatti, Moganavelli Singh
{"title":"Emerging Roles of Green-Synthesized Chalcogen and Chalcogenide Nanoparticles in Cancer Theranostics","authors":"F. Olawale, O. Oladimeji, M. Ariatti, Moganavelli Singh","doi":"10.1155/2022/6176610","DOIUrl":"https://doi.org/10.1155/2022/6176610","url":null,"abstract":"The last few decades have seen an overwhelming increase in the amount of research carried out on the use of inorganic nanoparticles. More fascinating is the tremendous progress made in the use of chalcogen and chalcogenide nanoparticles in cancer theranostics. These nanomaterials, which were initially synthesized through chemical methods, have now been efficiently produced using different plant materials. The paradigm shift towards the biogenic route of nanoparticle synthesis stems from its superior advantages of biosafety, eco-friendliness, and simplicity, among others. Despite a large number of reviews available on inorganic nanoparticle synthesis through green chemistry, there is currently a dearth of information on the green synthesis of chalcogens and chalcogenides for cancer research. Nanoformulations involving chalcogens such as sulfur, selenium, and tellurium and their respective chalcogenides have recently emerged as promising tools in cancer therapeutics and diagnosis. Similar to other inorganic nanoparticles, chalcogens and chalcogenides have been synthesized using plant extracts and their purified biomolecules. In this review, we provide an up-to-date discussion of the recent progress that has been made in the plant-mediated synthesis of chalcogens and chalcogenides with a special focus on their application in cancer theranostics.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":"40 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2022-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90470696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of Nanobiotechnology Towards Agri-Food System","authors":"Niguse Hotessa Halake, Jara Muda Haro","doi":"10.1155/2022/6108610","DOIUrl":"https://doi.org/10.1155/2022/6108610","url":null,"abstract":"The major challenge of modern agriculture is to satisfy actual and future global food demands efficiently. This great challenge requires combined efforts to preserve natural resources to support intensive agriculture while limiting detrimental impacts on the environment. One of these efforts is using nanobiotechnology. Nanobiotechnology is the application of nanotechnology in biological science. Nanotechnology is the science of manipulating materials at the nanoscale (1 nm = 10ˉ⁹ m). This review summarizes the potential of nanobiotechnology for its importance in increasing yield in agriculture and providing consumers with quality and contamination-free food. In the agriculture sector, nanobiotechnology is necessarily used as fertilizers (nanofertilizers) for crop yield improvement, pesticides (nanopesticides) for crop protection, and nanobiosensors for the detection of crop pathogens, soil conditions, and vegetation conditions, Similarly, intelligent food packaging, and detection of pathogens, adulterants, and toxins in food are its importance in the food sector.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":"21 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2022-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83280301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Graphene Oxide Nanoadsorbent for the Removal of Fluoride Ion from Groundwater: Adsorbent Performance and Adsorption Mechanism","authors":"Bayisa Meka Chufa, B. Gonfa, T. Y. Anshebo","doi":"10.1155/2022/7371227","DOIUrl":"https://doi.org/10.1155/2022/7371227","url":null,"abstract":"The deterioration of the quality of groundwater by fluoride is the cause of shortage of drinking water supply in the rift valley region. Most people living in the rural areas are using groundwater as the source of their potable water; however, it is contaminated with high concentrations of fluoride ion above the permissible level. Hence, this study was designed to investigate the adsorption of fluoride from groundwater by graphene oxide (GO) under specific conditions, such as: agitation rate of 120 rpm, contact time of 90 minutes, adsorbent dosage of 0.42 mg/L, initial fluoride concentration of 10 mg/L, and pH of 6.8. The result obtained showed 99.3% fluoride removal from the NaF prepared solution and 91.6% fluoride removal from the real sample. The retained properties of GO after adsorption observed on UV–Vis analysis confirmed that the adsorbent can be recyclable. The result obtained also showed that the adsorption kinetics with the coefficient of determination (R2) for pseudo-second order (SSO) and pseudo-first order (SFO) were 0.99 and 0.96, respectively. Based on these results, the adsorption of fluoride onto GO is a pseudo-second-order kinetics type. According to the result, the Freundlich isotherm model showed a good fit to the experiment with R2 (0.99). The adsorption capacity of the adsorbent was found to be 301.43 mg/g. Hence, this study showed that GO is the preferred adsorbent for the removal of fluoride from groundwater.","PeriodicalId":16378,"journal":{"name":"Journal of Nanotechnology","volume":"44 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2022-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84997543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}