Journal of interventional cardiology最新文献

{"title":"Clinical and Laboratory Predictors of Long-Term Outcomes after Catheter Ablation for a Ventricular Electrical Storm","authors":"Grzegorz Sławiński,&nbsp;Maja Hawryszko,&nbsp;Julia Dyda-Kristowska,&nbsp;Tomasz Królak,&nbsp;Maciej Kempa,&nbsp;Dariusz Świetlik,&nbsp;Dariusz Kozłowski,&nbsp;Ludmiła Daniłowicz-Szymanowicz,&nbsp;Ewa Lewicka","doi":"10.1155/2024/5524668","DOIUrl":"10.1155/2024/5524668","url":null,"abstract":"<p><i>Background</i>. Ventricular electrical storm (VES) is characterized by the occurrence of multiple episodes of sustained ventricular arrhythmias (VA) over a short period of time. Radiofrequency ablation (RFA) has been reported as an effective treatment in patients with ventricular tachycardia (VT). <i>Objective</i>. The aim of the present study was to indicate the short-term and long-term predictors of recurrent VA after RFA was performed due to VES. <i>Methods</i>. A retrospective, single-centre study included patients, who had undergone RFA due to VT between 2012 and 2021. In terms of the short-term (at the end of RFA) effectiveness of RFA, the following scenarios were distinguished: complete success: inability to induce any VT; partial success: absence of clinical VT; failure: inducible clinical VT. In terms of the long-term (12 months) effectiveness of RFA, the following scenarios were distinguished: effective ablation: no recurrence of any VT; partially successful ablation: VT recurrence; ineffective ablation: VES recurrence. <i>Results</i>. The study included 62 patients. Complete short-term RFA success was obtained in 77.4% of patients. The estimated cumulative VT-free survival and VES-free survival were, respectively, 28% and 33% at the 12-month follow-up. Ischemic cardiomyopathy and complete short-term RFA success were predictors of long-term RFA efficacy. Neutrophil to lymphocyte ratio (NLR) and GFR &lt;60 mL/min/1.73 m² were associated with VES recurrence. NLR ≥2.95 predicted VT and/or VES recurrence with a sensitivity of 66.7% and specificity of 72.2%. <i>Conclusion</i>. Ischemic cardiomyopathy and short-term complete success of RFA were predictors of no VES recurrence during the 12-month follow-up, while NLR and GFR &lt;60 ml/min/1.73 m² were associated with VES relapse.</p>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2024 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2024/5524668","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139688903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Ticagrelor and Clopidogrel in Elective Coronary Stenting: A Double Blind Randomized Clinical Trial","authors":"Mohammadjavad Mehdizadeh Parizi,&nbsp;Reza Golchin Vafa,&nbsp;Amin Ahmadi,&nbsp;Reza Heydarzade,&nbsp;Mehrdad Sadeghi,&nbsp;Amin Khademolhossseini,&nbsp;Farhang Amiri,&nbsp;Soroush Khoshnood Mansorkhani,&nbsp;Ali Tavan,&nbsp;Nazanin Hosseini,&nbsp;Mohammad Montaseri,&nbsp;Seyed Ali Hosseini,&nbsp;Javad Kojuri","doi":"10.1155/2023/5544440","DOIUrl":"10.1155/2023/5544440","url":null,"abstract":"<div>\u0000 <p><i>Background</i>. Dual antiplatelet therapy with a P2Y12 inhibitor (e.g., clopidogrel and ticagrelor) and aspirin is recommended for at least one year after percutaneous coronary intervention (PCI) to prevent further myocardial infarction and stent thrombosis as the major adverse effects of PCI. <i>Methods</i>. This randomized clinical trial was conducted from October 2022 to March 2023. Patients who had undergone elective PCI were included in the study. Patients were randomized into two different groups. One group took ASA 80 mg and clopidogrel 75 mg once daily, while the other took ASA 80 mg once daily and ticagrelor 90 mg twice daily. After six months of close follow-up, patients were asked to score their dyspnea on a 10-point Likert scale. They were also asked about dyspnea on exertion, paroxysmal nocturnal dyspnea (PND), bleeding, and the occurrence of major adverse cardiovascular events (MACEs). <i>Results</i>. 223 patients were allocated to the clopidogrel group and 214 to the ticagrelor group. In the ticagrelor group, 95 patients (44.3%) reported dyspnea at rest, compared with only 44 patients (19.7%) in the clopidogrel group (<i>P</i> &lt; 0.001). MACEs occurred in 7 patients (2.8%) in the ticagrelor group, compared with 16 (7.6%) in the clopidogrel group (<i>P</i> = 0.031). Eight patients (3.8%) reported bleeding with ticagrelor, as did seven (3.2%) with clopidogrel (<i>P</i> = 0.799). <i>Conclusions</i>. New-onset dyspnea was recorded more frequently with ticagrelor than clopidogrel, yet fewer MACEs occurred with ticagrelor (ClinicalTrials.gov number: NCT05858918).</p>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2023 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/5544440","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139052888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitral Valve Transcatheter Edge-to-Edge Repair Volumes and Trends","authors":"Kris Kumar,&nbsp;Timothy F. Simpson,&nbsp;Harsh Golwala,&nbsp;Adnan K. Chhatriwalla,&nbsp;Scott M. Chadderdon,&nbsp;Robert L. Smith,&nbsp;Howard K. Song,&nbsp;Ryan R. Reeves,&nbsp;Paul Sorajja,&nbsp;Firas E. Zahr","doi":"10.1155/2023/6617035","DOIUrl":"10.1155/2023/6617035","url":null,"abstract":"<div>\u0000 <p><i>Background</i>. Despite an association between operator volumes and procedural success, there remains an incomplete understanding of the contemporary utilization and procedural volumes for mitral valve transcatheter edge-to-edge repair (MTEER). We aimed to identify annual operator procedural volumes, temporal trends, and geographic variability for MTEER among Medicare patients in the United States (US). <i>Methods</i>. We queried the National Medicare Provider Utilization and Payment Database for a CPT code (33418) specific for MitraClip device from 2015 through 2019. We analyzed annual operator procedural volumes and incidence and identified longitudinal and geographic trends in MTEER utilization. <i>Results</i>. From 2015 through 2019, a total of 27,034 MTEER procedures were performed among Medicare patients in the US. The nationwide incidence increased from 6.2 per 100,000 patients in 2015 to 23.8 per 100,000 patients in 2019, a 283% increase over the study period (<i>P</i>_trend &lt; 0.001). The incidence of MTEER by state varied by nearly 900% (range 5.5 to 54.9 per 100,000 person-years). In 2019, the mean annual MTEER operator annual volume was 9.1 MTEER procedures and had grown from 6.2 per year in 2015. <i>Conclusions</i>. In this nationwide study of Medicare beneficiaries in the United States, we identified a significant and sustained increase in the utilization of MTEER devices and operators and growth in annual procedural volumes from 2015 through 2019 with considerable variability in utilization by state. Further studies are needed to understand the clinical impact of variability in utilization and the optimal procedural volumes to ensure high efficacy outcomes and maintain critical access to MTEER therapies.</p>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2023 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/6617035","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138745321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-Hospital and 1-Year Clinical Results from the French Registry Using Polymer-Free Sirolimus-Eluting Stents in Acute Coronary Syndrome and Stable Coronary Artery Disease","authors":"Quentin Landolff,&nbsp;Marine Quillot,&nbsp;Fabien Picard,&nbsp;Patrick Henry,&nbsp;Georgios Sideris,&nbsp;Olivier Bizeau,&nbsp;Christophe Piot,&nbsp;Bernard Jouve,&nbsp;Jérôme Rischner,&nbsp;Mourad Mejri,&nbsp;Claude Charmasson,&nbsp;Raphael Lasserre,&nbsp;Hervé Pouliquen,&nbsp;Thierry Joseph,&nbsp;Jacques Monsegu,&nbsp;Bernard Karsenty,&nbsp;Victoria Martin Yuste,&nbsp;Nicolas Richet,&nbsp;Guy Lapeyre,&nbsp;Fabrizio Beverelli,&nbsp;Farzin Beygui,&nbsp;René Koning","doi":"10.1155/2023/8907315","DOIUrl":"10.1155/2023/8907315","url":null,"abstract":"<div>\u0000 <p><i>Objectives</i>. The aim of this postmarket clinical study was to assess the safety and efficacy of the latest generation polymer-free sirolimus-eluting stents (PF-SES) in an all-comers population comparing outcomes in stable coronary artery disease (CAD) versus acute coronary syndrome (ACS) in France. <i>Background</i>. The efficacy and safety of the first-generation PF-SES have already been demonstrated by randomized controlled trials and “all-comers” observational studies. <i>Methods</i>. For this all-comers observational, prospective, multicenter study, 1456 patients were recruited in 22 French centers. The primary endpoint was target lesion revascularization (TLR) rate at 12 months and secondary endpoints included major adverse cardiac events (MACE) and bleeding. <i>Results</i>. 895 patients had stable CAD and 561 had ACS. At 12 months, 2% of patients had a TLR, with similar rates between stable CAD and ACS (1.9% vs 2.2%, <i>p</i> = 0.7). The overall MACE rate was 5.2% with an expected higher rate in patients with ACS as compared to those with stable CAD (7.3% vs 3.9%, <i>p</i> = 0.007). The overall bleeding event rate was 4.5%, with similar rates in stable CAD as compared to ACS patients (3.8% vs 5.6%, <i>p</i> = 0.3). Dual antiplatelet therapy (DAPT) interruptions prior to the recommended duration occurred in 41.7% of patients with no increase in MACE rates as compared to patients who did not prematurely interrupt DAPT (3.9% vs 6.1%, <i>p</i> = 0.073). <i>Conclusions</i>. The latest generation PF-SES is associated with low clinical event rates in these all-comers patients. There was a high rate of prematurely terminated DAPT, without any effect on MACE at 12 months. This trial is registered with NCT03809715.</p>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2023 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/8907315","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138580183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neo-Commissural Alignment by Withdrawing and Readvancing the Delivery System during Transcatheter Aortic Valve Replacement with Self-Expanding Prosthesis","authors":"Xian Liu,&nbsp;Yingdong Wang,&nbsp;Yuhe Sheng,&nbsp;Yaling Han,&nbsp;Quanmin Jing,&nbsp;Geng Wang,&nbsp;Zhenyang Liang,&nbsp;Yang Li,&nbsp;Bin Wang,&nbsp;Kai Xu,&nbsp;Li Yang,&nbsp;Gary S. Mintz","doi":"10.1155/2023/1060481","DOIUrl":"10.1155/2023/1060481","url":null,"abstract":"<div>\u0000 <p><i>Objective</i>. To investigate the feasibility of obtaining neo-commissural alignment by withdrawing and readvancing the delivery system during transcatheter aortic valve replacement (TAVR) with self-expanding prosthesis. <i>Methods</i>. TAVR was performed in five patients with severe aortic valve stenosis by the femoral approach. The delivery catheter was withdrawn and readvanced with the opposite orientation when the Venus-A plus transcatheter heart valve (THV) centre marker was found to be overlapped with or close to the left marker at the aortic annulus level on the fluoroscopic image at the projection of the right and left coronary cusps superimposing. Neo-commissural alignment was evaluated by comparing the aortic computed tomography before TAVR with it after TAVR. <i>Results</i>. The THV centre marker was overlapped with or close to the right marker at the aortic annulus level on the fluoroscopic image at the projection of the right and left coronary cusps superimposed in all the present five patients after withdrawing and readvancing the delivery system. The commissural angle deviation before vs. post TAVR was 12.3° ± 7.0°. Three of five patients had neo-commissural alignment. Two of the five patients had mild neo-commissural misalignment. <i>Conclusions</i>. It is possible to obtain the neo-commissural alignment by controlling delivery catheter insertion orientation using the markers on the inflow of the Venus-A plus valve.</p>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2023 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/1060481","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138568398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global Research Hotspots in Venous Thromboembolism Anticoagulation: A Knowledge-Map Analysis from 2012 to 2021","authors":"Jia Wang,&nbsp;Yang-Xi Liu,&nbsp;Yi-Dan Yan,&nbsp;Li Liu,&nbsp;Chi Zhang,&nbsp;Mang-Mang Pan,&nbsp;Hou-Wen Lin,&nbsp;Zhi-Chun Gu","doi":"10.1155/2023/4717271","DOIUrl":"10.1155/2023/4717271","url":null,"abstract":"<div>\u0000 <p><i>Background</i>. Venous thromboembolism (VTE) is a common cardiovascular disease that seriously threatens human lives. Anticoagulant therapy is considered to be the cornerstone of VTE treatment. An increasing number of studies has been updated in the VTE anticoagulation field. However, no bibliometric analyses have assessed these publications comprehensively. Therefore, our study aimed to analyze the global status, hotspots, and trends of anticoagulant therapy for VTE. <i>Methods</i>. The relevant literature on VTE anticoagulation published between 2012 and 2021 was retrieved and collected from the Web of Science Core Collection database. VOSviewer, Cooccurrence Matrix Builder, gCLUTO, and some online visualization tools were adopted for bibliometric analysis. <i>Results</i>. A total of 15,152 related articles were retrieved. In recent years, the research output of VTE anticoagulation gradually increased. The United States was the most productive country. International cooperation is concentrated in North America and Europe; the most influential documents, journals, authors, and organizations were also from these two continents. Research hotspots mainly focus on clinical guidelines, VTE in special populations, non-vitamin K oral anticoagulants (NOACs), and parenteral anticoagulation. The research frontiers and trends include the assessment of NOACs and the antithrombotic management of VTE complicated with coronavirus disease 2019 (COVID-19). <i>Conclusion</i>. This bibliometric analysis provides a systematic overview of the VTE anticoagulation research, which will facilitate researchers to better understand the situation of VTE anticoagulation. Future studies should be dedicated to NOACs application and VTE-combined COVID-19 patients.</p>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2023 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138460339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Center Volumes Correlate with Likelihood of Stent Implantation in German Coronary Angiography","authors":"Vera Oettinger,&nbsp;Philip Hehn,&nbsp;Christoph Bode,&nbsp;Manfred Zehender,&nbsp;Constantin von zur Mühlen,&nbsp;Dirk Westermann,&nbsp;Peter Stachon,&nbsp;Klaus Kaier","doi":"10.1155/2023/3723657","DOIUrl":"10.1155/2023/3723657","url":null,"abstract":"<div>\u0000 <p><i>Aims</i>. Literature on percutaneous coronary intervention (PCI) stated an inverse relationship between hospital volume and mortality, but the effects on other characteristics are unclear. <i>Methods</i>. Using German national records, all coronary angiographies with coronary artery disease in 2017 were identified. We applied risk-adjustment to account for differences in population characteristics. <i>Results</i>. Of overall 528,188 patients, 55.22% received at least one stent, with on average 1.01 stents implanted in all patients. Based on those patients who received at least one stent, this corresponds to an average number of 1.82 stents. In-hospital mortality across all patients was 2.93%, length of hospital stay was 6.46 days, and mean reimbursement was €5,531. There were comparatively more emergency admissions in low volume centers and more complex cases (3-vessel disease, left main stenosis, and in-stent stenosis) in high volume centers. In multivariable regression analysis, volume and likelihood of stent implantation (<i>p</i> = 0.003) as well as number of stents (<i>p</i> = 0.020) were positively correlated. No relationship was seen for in-hospital mortality (<i>p</i> = 0.105), length of stay (<i>p</i> = 0.201), and reimbursement (<i>p</i> = 0.108). Nonlinear influence of volume suggests a ceiling effect: In hospitals with ≤100 interventions, likelihood and number of implanted stents are lowest (∼34% and 0.6). After that, both rise steadily until a volume of 500 interventions. Finally, both remain stable in the categories of over 500 interventions (∼60% and 1.1). <i>Conclusion</i>. In PCI, lower volume centers contribute to emergency care. Higher volume centers treat more complex cases and show a higher likelihood of stent implantations, with a stable safety.</p>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2023 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/2023/3723657","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135192719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous Coronary Intervention versus Coronary Artery Bypass Grafting for Chronic Total Occlusion of Coronary Arteries: A Systematic Review and Meta-Analysis","authors":"Chenyang Wang,&nbsp;Sheng Liu,&nbsp;Raimov Kamronbek,&nbsp;Siyao Ni,&nbsp;Yunjiu Cheng,&nbsp;Huiyuan Yan,&nbsp;Ming Zhang","doi":"10.1155/2023/9928347","DOIUrl":"10.1155/2023/9928347","url":null,"abstract":"<div>\u0000 <p><i>Introduction</i>. Chronic total occlusion (CTO) of coronary arteries constitutes a substantial clinical challenge and has historically been managed through medical management and coronary artery bypass grafting (CABG). However, with the advancement in interventional technology, the success rate of percutaneous treatment has been significantly improved, and percutaneous coronary intervention (PCI) has emerged as a primary mode of treatment for CTOs, demonstrating remarkable clinical efficacy. The objective of this systematic review and meta-analysis is to evaluate and contrast the outcomes of PCI and CABG in patients with CTO. <i>Methods and Results</i>. A systematic search was conducted in the databases of PubMed, Embase, and Web of Science. The primary endpoints evaluated in this meta-analysis were the occurrence of major adverse cardiac events (MACE) and all-cause mortality. Secondary endpoints included myocardial infarction (MI), cardiac death, and the need for repeat revascularization. Nine studies, encompassing a total of 8,674 patients, were found to meet the criteria for inclusion and had a mean follow-up duration of 4.3 years. The results of the meta-analysis revealed that compared to CABG, PCI was associated with a lower incidence of all-cause mortality (RR: 0.78, 95% CI: 0.66–0.92; <i>P</i> = 0.003) and cardiac death (RR: 0.55; 95% CI: 0.31–0.96; <i>P</i> &lt; 0.05), but an increased risk of myocardial infarction (MI) (RR: 1.96; 95%CI: 1.07–3.62; <i>P</i> &lt; 0.05) and repeat revascularization (RR: 7.13; 95% CI: 5.69–8.94; <i>P</i> &lt; 0.00001). There was no statistically significant difference in MACE (RR: 1.11; 95% CI: 0.69–1.81; <i>P</i> = 0.66) between the PCI and CABG groups. <i>Conclusion</i>. In the present meta-analysis comparing PCI and CABG in patients with chronic total occlusion of the coronary arteries, the results indicated that PCI was superior to CABG in reducing all-cause mortality and cardiac death but inferior in decreasing myocardial infarction and repeat revascularization. There was no statistically significant difference in MACE between the two groups.</p>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2023 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643034/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107591496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapy Efficacy of Idiopathic Ventricular Extrasystoles: A Real Life Study","authors":"Aliisa Lönnrot,&nbsp;Jaakko Inkovaara,&nbsp;Olli Arola,&nbsp;Tero Penttilä,&nbsp;Heikki Mäkynen,&nbsp;Katriina Aalto-Setälä,&nbsp;Sinikka Yli-Mäyry","doi":"10.1155/2023/5590422","DOIUrl":"10.1155/2023/5590422","url":null,"abstract":"<div>\u0000 <p><i>Background</i>. Ventricular extrasystoles (VESs) are common and often harmless in a healthy heart, but they can significantly affect the quality of life. If changes in lifestyle and antiarrhythmic medication are not enough, invasive and often curative catheter ablation can be considered. Better understanding of the conformation of VESs with a 12-lead ECG, as well as their precise localization, have increased their treatment with catheter ablation. Our goal was to determine whether the anatomical site of VES had an effect on procedure success. We also analyzed the safety of the procedure and patient-related factors affecting the results. <i>Materials and Methods</i>. In this retrospective study, we analyzed the medical records of 63 consecutive patients with multiple idiopathic VESs treated by catheter ablation at Heart Hospital, Tampere University Hospital, during 2017 and 2018. Patients with structural heart disease were excluded. Ablation success was estimated with two endpoints, primary and follow-up success. <i>Results</i>. The majority of the patients received treatment on the right ventricular outflow tract (66.7%), others on the left ventricle (17.5%), or the aortic cusp (9.5%). The site of origin remained unknown in four procedures (6.3% of patients). Primary success was observed in 48 procedures (76.2%). During the follow-up period of three months, the procedure was successful in 70.3% of the cases. The anatomical site of VES had no significant effect on either primary or follow-up success. Those with a successful follow-up result had a lower body mass index (BMI = 26.4) than those who had an unsuccessful result (BMI = 28.7; <i>p</i> = 0.069); this did not reach statistical significance, potentially due to the small study population size. Complications were observed in three patients (4.5%). All of them were related to the catheter insertion site. <i>Conclusions</i>. For a symptomatic patient, catheter ablation is an effective and often fully curative treatment. The success rate was similar regardless of the site of VESs. This suggests that catheter ablation should also be assessed early on for other cases besides classic right ventricular outflow tract VESs. A high BMI was the only factor associated with a poor procedure success rate. The procedure itself is safe, and adverse effects are rare. The radiation dose is also low partly due to the current magnetic navigation method.</p>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2023 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71482528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Differences of Quantitative Flow Ratio in Coronary Artery Stenosis with or without Atrial Fibrillation","authors":"Wenbin Lu,&nbsp;Xiaoguo Zhang,&nbsp;Gaoliang Yan,&nbsp;Genshan Ma","doi":"10.1155/2023/7278343","DOIUrl":"10.1155/2023/7278343","url":null,"abstract":"<div>\u0000 <p>Quantitative flow ratio (QFR) is a new method for the assessment of the extent of coronary artery stenosis. But it may be obscured by the cardiac remodeling and abnormal blood flow of the coronary artery when encountering atrial fibrillation (AF). The present study aimed to examine the impact of these changed structures and blood flow of coronary arteries on QFR results in AF patients. <i>Methods and Results</i>. We evaluated QFR in 223 patients (112 patients with AF; 111 non-AF patients served as controls) who had undergone percutaneous coronary intervention (PCI) due to severe stenoses in coronary arteries. QFR of the target coronary was determined according to the flow rate of the contrast agent. Results showed that AF patients had significantly higher QFR values than control (0.792 ± 0.118 vs. 0.685 ± 0.167, <i>p</i> &lt; 0.001). We further analyzed local QFR around the stenoses (0.858 ± 0.304 vs. 0.756 ± 0.146, <i>p</i> = 0.002), residual QFR (0.958 ± 0.055 vs. 0.929 ± 0.093, <i>p</i> = 0.005), and index QFR (0.807 ± 0.108 vs. 0.713 ± 0.152, <i>p</i> &lt; 0.001) in these two groups of patients with and without AF. Further analysis revealed that QFR in AF patients was negatively correlated with coronary flow velocity (<i>R</i> = −0.22, <i>p</i> = 0.02) and area of stenosis (<i>R</i> = −0.70, <i>p</i> &lt; 0.001) but positively correlated with the minimum lumen area (MLA) (<i>R</i> = 0.47, <i>p</i> &lt; 0.001). <i>Conclusion</i>. AF patients with coronary artery stenosis have higher QFR values, which are associated with decreased blood flow velocity, smaller stenosis, and larger MLA in AF patients upon cardiac remodeling.</p>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2023 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49690942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}