Jonathan J. Park , Dylan Richards , Po-He Tseng , Toshiya Ebata , Akihiko Ikoma , Paras P. Vakharia , Stephanie M. Rangel , Amy S. Paller , Shuai Xu
{"title":"Methods to Validate Digital Health Technologies for Dermatology","authors":"Jonathan J. Park , Dylan Richards , Po-He Tseng , Toshiya Ebata , Akihiko Ikoma , Paras P. Vakharia , Stephanie M. Rangel , Amy S. Paller , Shuai Xu","doi":"10.1016/j.jid.2025.08.013","DOIUrl":"10.1016/j.jid.2025.08.013","url":null,"abstract":"<div><div>The integration of wearable medical devices and digital health technologies (DHTs) in health care has grown significantly during the past 2 decades, particularly in dermatology, in which objective measurement of symptoms such as itch remains challenging. This review examines the evolution of DHTs in dermatology, focusing on the validation frameworks necessary for their implementation in clinical trials and research. We discuss the key stages of validation: hardware validation to ensure device reliability, analytical validation to transform raw sensor data into meaningful metrics, and clinical validation to demonstrate utility in specific patient populations. We also address challenges in real-world implementation, including skin tolerance and device adherence issues that affect long-term wearability. Using the example of sensors for measuring nocturnal scratching in patients with atopic dermatitis, we illustrate how these validation frameworks are being applied to dermatological DHTs. As the field continues to advance, transparent reporting of validation protocols and results will be essential for establishing trust and ensuring effective integration of dermatological DHTs into clinical practice.</div></div>","PeriodicalId":16311,"journal":{"name":"Journal of Investigative Dermatology","volume":"145 11","pages":"Pages 2668-2675"},"PeriodicalIF":5.7,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145017081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editor's Picks September 2025","authors":"","doi":"10.1016/j.jid.2025.06.1580","DOIUrl":"10.1016/j.jid.2025.06.1580","url":null,"abstract":"","PeriodicalId":16311,"journal":{"name":"Journal of Investigative Dermatology","volume":"145 9","pages":"Page 2119"},"PeriodicalIF":5.7,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144887177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Facing Our FAERS: Disproportionality Analyses, Signal Detection, and Interpretation","authors":"Ravi Ramessur, Joel M. Gelfand","doi":"10.1016/j.jid.2025.06.1579","DOIUrl":"10.1016/j.jid.2025.06.1579","url":null,"abstract":"","PeriodicalId":16311,"journal":{"name":"Journal of Investigative Dermatology","volume":"145 9","pages":"Pages 2115-2117"},"PeriodicalIF":5.7,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144887075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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