Journal of Marmara University Institute of Health Sciences最新文献

Elektro Çekim Yöntemi ile Çörek Otu ve Yün Yağı Takviyeli Yara Örtüsü Geliştirilmesi

Journal of Marmara University Institute of Health Sciences Pub Date : 2020-04-30 DOI: 10.35333/porta.2020.208

Erdem Şahin, Canberk Elmalı, Derya Saltık Çirkin, Muhammet Uzun

{"title":"Elektro Çekim Yöntemi ile Çörek Otu ve Yün Yağı Takviyeli Yara Örtüsü Geliştirilmesi","authors":"Erdem Şahin, Canberk Elmalı, Derya Saltık Çirkin, Muhammet Uzun","doi":"10.35333/porta.2020.208","DOIUrl":"https://doi.org/10.35333/porta.2020.208","url":null,"abstract":"Wool, which is the most important of animal fibers, is used as 100% or as a blend in textile protection. Thanks to its structural features, there are technical textile applications as well as used in daily life. Within the scope of this study, wool oil (lanolin), a by-product occurs during the wool processing, was used in the production of medical textiles with high added value. Black seed oil was used as a supplement to add further properties to the developed wound dressings. As clearly stated in the literature, Nigella Sativa seeds and Nigella Sativa oil have been tested on humans and their positive effect on human health has been well established. It has been observed that black seed has a wound-healing effect apart from the treatment and prevention of diseases. The wound healing process is a successive mixed process, and the use of wound dressing which has a correct content and feature will shorten this process. There are various types of wound dressings, these are; antibacterial, alginate, composite, hydrogel etc. Recent researches show the importance of nanofiber wound dressings produced with the electrospinning technique. The electrospinning technique generally enables the formation of nanoscale fibers from the polymer solution by applying an electric force at the kV level under small flow rates to the polymer solution formed at certain concentrations. In this study, a nanofiber the formed solutions were measured with the viscosity meter and conductivity meter before starting production. As a result, a nano-fiber-based structure was successfully obtained from the blend of wool and black seed oil by using the electrospinning method.","PeriodicalId":16169,"journal":{"name":"Journal of Marmara University Institute of Health Sciences","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87443022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Carbon Nanotube-Phosphorus Based Flame Retardant Combinations on Flammability of Polypropylene 碳纳米管-磷基复合阻燃剂对聚丙烯可燃性的影响

Journal of Marmara University Institute of Health Sciences Pub Date : 2019-04-30 DOI: 10.35333/PORTA.2019.21

Ayfer İrem Koca, M. E. Üreyen, G. Yuksel, F. Karaer

{"title":"Effects of Carbon Nanotube-Phosphorus Based Flame Retardant Combinations on Flammability of Polypropylene","authors":"Ayfer İrem Koca, M. E. Üreyen, G. Yuksel, F. Karaer","doi":"10.35333/PORTA.2019.21","DOIUrl":"https://doi.org/10.35333/PORTA.2019.21","url":null,"abstract":"The effects of multi-walled carbon nanotubes (MWCNTs) on fire behavior of phosphorus-based flame retardant (PBFR)/polypropylene (PP) were investigated. Two different type phosphorus-based flame retardant that commercially available; ammonium polyphosphate-based (Exolit AP 760) and organic phosphorous-based (Aflammit PCO 900) powders were studied to enhance the flammability of polypropylene . Phosphorus-based flame retardant content was fixed at 8 wt% of total flame retardant (FR) formulation. MWCNTs was incorporated into FR formulation at four different concentrations (0.5 wt% , 1.0 wt% , 1.5 wt% and 2.0 wt%). All composites were prepared by melt compounding in a twin-screw extruder followed by injection molding technique. Thermal properties and flammability of the prepared samples were determined by thermogravimetric analysis (TGA), limiting oxygen index (LOI) and micro combustion calorimetry (MCC). Incorporation of organic phosphorous-based powder into PP matrix showed a better fire performance compared to ammonium polyphosphate-based flame retardant by resulting in an 11.6 % higher LOI value. The LOI values decreased with the incorporation of MWCNTs into PP/ PBFR combinations; however, they still increased the thermal stability of each respective system. The addition of 2.0 wt% MWCNTs decreased the LOI value of PP/organic phosphorous-based FR system 5.2% higher than PP/ammonium polyphosphate-based FR system. The heat release rate of PP reduced in the presence of both PBFRs, but; increased with the introduction of MWCNTs.","PeriodicalId":16169,"journal":{"name":"Journal of Marmara University Institute of Health Sciences","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84631803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nano-akışkan Aşındırıcı Toz Miktarının Yüzey Kalitesine Etkilerinin İncelenmesi

Journal of Marmara University Institute of Health Sciences Pub Date : 2019-04-30 DOI: 10.35333/PORTA.2019.17

A. Özcan, M. Ay, Ayhan Etyemez

{"title":"Nano-akışkan Aşındırıcı Toz Miktarının Yüzey Kalitesine Etkilerinin İncelenmesi","authors":"A. Özcan, M. Ay, Ayhan Etyemez","doi":"10.35333/PORTA.2019.17","DOIUrl":"https://doi.org/10.35333/PORTA.2019.17","url":null,"abstract":"Bu calismada Minimum Miktarda Yaglama (MMY) sistemine katilan asindirici toz miktari ve kesme hizina bagli olarak islenmis yuzeylerdeki yuzey puruzlulugundeki degisimler incelenmistir. Kesme hizi olarak (V:100, 120, 140 ve 160 m/dk) ve kesme yontemi olarak (kuru, MMY, MMY+%1 Al 2 O 3 , MMY+%2 Al 2 O 3 , MMY+%4 Al 2 O 3 ve MMY+%6 Al 2 O 3 ) kesme parametreleri secilmistir. Deney malzemesi olarak yuksek sertlige ulasabilmek adina 59 HRC sertliginde sertlestirilmis 1.2379 soguk is takim celigi secilmis olup, kesici uc olarak ise yuksek sertlikte tornalama islemlerine dayanikli olan CBN kesici uc secilmistir. Kesme sivisina katilan asindirici toz olarak Al 2 O 3 nanopartikuller kullanilmis, deney sonrasinda yuzey kalitesindeki degisimleri gormek adina MAHR Perthometer M1 yuzey puruzluluk olcum aleti kullanilmistir. Deney sonuclari incelendiginde en iyi ortalama yuzey puruzlulugune, kesme hizinin 160 m/dk ve hacimsel nano-akiskan konsantrasyonunun %4 olarak uygulandigi deneyde 0,888 μm ile ulasilmistir. Ortalama yuzey puruzluluk degerinin en yuksek oldugu deney ise 100 m/dk kesme hizinda kuru kesme isleminde ortaya cikmistir. Farkli parametreler ile yapilan deneyler karsilastirildiginda kesme hizi ve nano-akiskan konsantrasyonundaki artisin yuzey kalitesine olumlu yonde etkisi oldugu sonucu ortaya cikmistir.","PeriodicalId":16169,"journal":{"name":"Journal of Marmara University Institute of Health Sciences","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90771344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

İnsan Odaklı Aydınlatma

Journal of Marmara University Institute of Health Sciences Pub Date : 2019-04-30 DOI: 10.35333/PORTA.2019.23

Özge Memiş

{"title":"İnsan Odaklı Aydınlatma","authors":"Özge Memiş","doi":"10.35333/PORTA.2019.23","DOIUrl":"https://doi.org/10.35333/PORTA.2019.23","url":null,"abstract":"Ozet Gecmis zamanlarda insanlar vakitlerinin cogunu dis ortamlarda ve gunes isigi altinda gecirmekteydi. Gunumuzde ise insanlar vakitlerinin cogunu ev, ofis, hastane, okul gibi kapali ortamlarda ve yapay aydinlatma kaynaklarinin olusturdugu isiklar altinda gecirmektedir. Gun isigi, gunesin konumundaki degisime gore gun icerisinde renk sicakligi, isik siddeti, isik rengi gibi parametrelerde degisim gosterdiginden dolayi dinamik yapilidir. Buna karsin yapay isik kaynaklari ile saglanan aydinlatma gun boyu sabittir. Insan sirkadiyen ritmi ve buna bagli biyolojik saati dunyanin aydinlik karanlik dongusu ile senkronizedir. Dolayisiyla kapali ortamlarda maruz kalinan aydinlatmaya bagli olarak insanlarin sirkadiyen ritimlerinin bozulmasindan kaynakli sorunlar olusabilir. Insanlarin yasam ve calisma alanlarina gunes isiginin dinamik atmosferinin tasinmasi ve biyolojik saat ile sirkadiyen ritimlerinin bozulmasinin onlenmesi amacindan “insan odakli aydinlatma” fikri dogmustur. Yapilan calismada insan odakli aydinlatma ve etkileri ele alinmistir. Abstract In the past, people have spent most of their time in an outdoors and in the sunlight. Nowadays, people spend most of their time in an indoors such as home, office, hospital, school and under the lights of artificial lighting sources. Daylight is dynamic due to changes in parameters such as color temperature, light intensity, light color during the day according to the change in the position of the sun. In contrast, lighting provided by artificial light sources is constant throughout the day. The human circadian rhythm and its associated biological clock are synchronized with the light dark cycle of the world. Therefore, depending on the lighting that is exposed in indoor environments, problems may arise due to the deterioration of the circadian rhythm of people. The idea of human centric lighting emerged in order to create a dynamic atmosphere of sunlight in people's life and working areas and to prevent the deterioration of the biological clock and circadian rhythms. In this study, human centric lighting and its effects are discussed.","PeriodicalId":16169,"journal":{"name":"Journal of Marmara University Institute of Health Sciences","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87432769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Nikel Alaşımlarının Farklı Soğutma/Yağlama Koşulları Altında Talaşlı İmalatının Kesme Kuvvetlerine Etkisi: Bir Derleme Çalışması

Journal of Marmara University Institute of Health Sciences Pub Date : 2019-04-30 DOI: 10.35333/PORTA.2019.20

M. Taşbaşi, M. Ay

{"title":"Nikel Alaşımlarının Farklı Soğutma/Yağlama Koşulları Altında Talaşlı İmalatının Kesme Kuvvetlerine Etkisi: Bir Derleme Çalışması","authors":"M. Taşbaşi, M. Ay","doi":"10.35333/PORTA.2019.20","DOIUrl":"https://doi.org/10.35333/PORTA.2019.20","url":null,"abstract":"Nikel alasimlari yuksek sicakliklarda mekanik ozelliklerini koruyabilme ve korozyona karsi yuksek direnc ozellikleri nedeniyle, yuksek sicaklik ve korozyona maruz kalan, havacilik ve uzay, nukleer enerji, petro-kimya endustrisi gibi guvenlik ve surdurulebilirligin hayati onem tasidigi kritik endustri uygulamalarinda onemli yer tutar. Nikel alasimlarinin gelismis ozellikleri, bu alasimlarin talasli imalati sirasinda yuksek kesme kuvvetleri, kesme bolgesi sicakligi ve sonrasinda birtakim problemlerin olusmasina neden olmaktadir. Birbirleriyle oldukca iliskili bu problemlere cozum olarak bazi yaklasimlar gelistirilmistir. Bu calisma, literaturde nikel alasimlarinin farkli sogutma/yaglama kosullarinda farkli talasli imalat yontemleriyle islenmesi ile ilgili calismalarin talasli imalat sirasinda olusan kesme kuvvetleri uzerindeki etkilerinin bir incelemesini sunar. Yapilan deneysel calismalarin cogunda, karakteristiklerine gore kuru, konvansiyonel, MQL(Minimum miktarda yaglama) ve kriyojenik kosullarda isleme metodlari uygulanmistir. Ancak bu metodlarin yanisira, etkin bir uygulama icin kesme parametreleri, takim kaplamasi, nozul konumlari gibi bircok unsurun goz onune alinmasi gerekmektedir. Calismalar, kesme kuvvetlerini azaltma konusunda kriyojenik metodun yuksek hizlarda diger metodlarin coguna gore oldukca etkili oldugunu gostermistir. Ancak kriyojenik metod tek basina yeterli olmamakta ve alternatif olarak kriyojenik ve MQL metodlarinin birlesimi olan hibrid KriyoMQL sogutma/yaglama metodunun kullanimi yayginlasmaya baslamistir. Literaturdeki arastirmalarinda isigina bu metodun nikel alasimlarinin talasli imalatinda kesme kuvvetlerinin ve kesme bolgesi sicakliklarinin azaltilmasinda gelecekte etkin bir metod olabilecegi sonucuna varilmistir.","PeriodicalId":16169,"journal":{"name":"Journal of Marmara University Institute of Health Sciences","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81321460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation On The Effect Of Garment Fit On Thermal Transfer Performance Of Clothing By Combining Non-Contact Measuring Tools 结合非接触式测量工具研究服装合身对服装传热性能的影响

Journal of Marmara University Institute of Health Sciences Pub Date : 2019-04-30 DOI: 10.35333/PORTA.2019.18

Sertaç Güney

{"title":"Investigation On The Effect Of Garment Fit On Thermal Transfer Performance Of Clothing By Combining Non-Contact Measuring Tools","authors":"Sertaç Güney","doi":"10.35333/PORTA.2019.18","DOIUrl":"https://doi.org/10.35333/PORTA.2019.18","url":null,"abstract":"Vucuda tam oturan spor kiyafetleri genellikle, orme kumaslardan uretilir ve giyildiginde uzar ve uzamis halde vucut yuzeyinde kalirlar. Vucut yuzeyiyle dogrudan temas ettikleri icin termal konfor ozellikleri genel giysi konforunda etkilidir. Bu calismada, vucuda oturma durumunun ve kumas uzamasinin, giysinin termal transfer performansi uzerindeki etkileri arastirilmistir. Kizilotesi termal kamera ve ucboyutlu sanal giysi simulasyonunun birlesimini kullanan bu yontem, farkli vucut bolgeleri uzerindeki kumas uzamalari ve giysi yuzey sicakliklari dikkate alinarak gelistirilmistir. Gogus ve bel olcumleri degistirilerek iki tip tisort uretilmis ve farkli beden olculerindeki katilimcilarla giyim denemeleriyle isi transfer performanslari incelenmistir. Kumas uzama degerleri, katilimcilarla ayni vucut olculerine sahip olan ucboyutlu simulasyondaki sanal mankenler uzerinden elde edilmistir. Termal kamera yazilimiyla (Flir Tools) giyim denemesi protokolune gore farkli vucut bolgelerindeki sicaklik degisiklikleri incelenmistir. Deneysel sonuclar, giysinin vucuda oturma durumunun ve kumas uzamasinin, isi transferini ve giysi yuzey sicakliklarini etkiledigini gostermektedir. Spor giyim endustrisinde, ozellikle performans spor kiyafetlerinin tasariminda en uygun vucuda oturma orani tanimlanmalidir.","PeriodicalId":16169,"journal":{"name":"Journal of Marmara University Institute of Health Sciences","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85952722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of Water Permeability of Ultrasonic Seaming on PU Coated Fabrics 聚氨酯涂层织物超声缝的透水性研究

Journal of Marmara University Institute of Health Sciences Pub Date : 2019-04-30 DOI: 10.35333/PORTA.2019.22

Ayşe Şevkan Macit, Bahar Tiber

{"title":"Investigation of Water Permeability of Ultrasonic Seaming on PU Coated Fabrics","authors":"Ayşe Şevkan Macit, Bahar Tiber","doi":"10.35333/PORTA.2019.22","DOIUrl":"https://doi.org/10.35333/PORTA.2019.22","url":null,"abstract":"Teknik tekstiller, tekstil ve konfeksiyon sektorunde onemli bir yer tutmaktadir. Teknik tekstillerde, konvansiyonel dikis yontemlerinin yani sira ultrasonik dikis yontemi, fonksiyonel tekstillerin dikis islemlerinde kullanilan alternatif yontemlerden biridir. Bu calismada, igne ve iplik kullaniminin gerekmedigi ultrasonik dikis yonteminin PU kaplamali kumaslarin su gecirmezlik ozelligi uzerindeki etkileri konvansiyonel dikis yontemleri ile karsilastirmali olarak incelenmistir. Farkli dikis parametreleri ile elde edilen dikilmis kumaslar yikama islemine tabi tutulmus ve bu kumaslarin su gecirmezlik ozellikleri yikama islemlerinden once ve yikama islemlerinden sonra test edilmistir. Dikis tipi, kumas tipi, ultrasonik dikis hizi ve yikama islemi acisindan degerlendirilen sonuclar istatistiksel olarak analiz edilmistir. Test sonuclarina gore, ultrasonik olarak dikilmis kumaslarin su gecirmezlik ozellikleri, konvansiyonel olarak dikilmis kumaslardan daha yuksektir. Ultrasonik dikisle dikilmis kumaslar ile konvansiyonel olarak dikilmis kumaslarin su gecirmezlik degerleri arasindaki fark istatistiksel olarak anlamli bulunmustur. Kumaslarin su gecirmezlik ozelliginin diger parametrelerle iliskili oldugu belirlenmistir.","PeriodicalId":16169,"journal":{"name":"Journal of Marmara University Institute of Health Sciences","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80347985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Antibacterial Properties of Polyurethane / Benzalkonium Chloride Nanofibers 聚氨酯/苯扎氯铵纳米纤维的抗菌性能

Journal of Marmara University Institute of Health Sciences Pub Date : 2019-04-30 DOI: 10.35333/PORTA.2019.19

Ayşe Arslan

{"title":"Antibacterial Properties of Polyurethane / Benzalkonium Chloride Nanofibers","authors":"Ayşe Arslan","doi":"10.35333/PORTA.2019.19","DOIUrl":"https://doi.org/10.35333/PORTA.2019.19","url":null,"abstract":"The textile sector brings us different functional features besides our need for dressing. One of them is to give antibacterial properties to textile structures. Antibacterial property increases the quality of life by protecting people against bacterial attacks. It is possible to achieve antibacterial activity at different stages of textile production processes. One of these processes is the electrospinning method, which makes it possible to add antibacterial substances into a polymer containing solution to be processed to a nanofiber structure. In this study, nanofiber structures were obtained by electrospinning from polyurethane (PU)/benzalkonium chloride (BAC) solutions at different concentrations. Then, their morphological, mechanical and antibacterial characteristics were investigated. According to the results, the produced fiber membranes had nanometer size. The nanofiber surfaces were intensive and uniform when BAC concentration was 0.5% and 1.0%. But, the uniformity lost at the higher BAC concentrations. The thinnest fiber diameter of nanofibers was 423±80nm. The strongest (6,42MPa) nanofiber structure was observed when the electrospinning solution included 0.98% PU and 1% BAC. The antibacterial activities of the fabrics were tested against gram-negative ( E. coli and P. aeruginosa ) and gram-positive ( B. subtilis and S. aureus ) bacteria. The fabrics showed antibacterial activity with a dose dependent manner against all the tested bacteria by the order of B. subtilis > S. aureus > E. coli > P. aeruginosa .","PeriodicalId":16169,"journal":{"name":"Journal of Marmara University Institute of Health Sciences","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81328476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effects of acute hyperglycemia on oxidative stress and nitric oxide bioavailability in platelets 急性高血糖对血小板氧化应激和一氧化氮生物利用度的影响

Journal of Marmara University Institute of Health Sciences Pub Date : 2015-12-29 DOI: 10.5455/MUSBED.20150715121543

A. Şener, N. Altindiş, Ozge C. Dogan

{"title":"The effects of acute hyperglycemia on oxidative stress and nitric oxide bioavailability in platelets","authors":"A. Şener, N. Altindiş, Ozge C. Dogan","doi":"10.5455/MUSBED.20150715121543","DOIUrl":"https://doi.org/10.5455/MUSBED.20150715121543","url":null,"abstract":"Amac: Diyabette, trombositlerin aktivasyona ve trombus olusumuna egilimi artmaktadir. Nitrik oksit (NO), ozellikle trombositten zengin trom¬buslara yeni trombositlerin katilmasini sinirlandirarak trombosit fonksi¬yonlarinda onemli rol oynar. Ancak, NO hucrelerde oksidatif/nitrozatif stresi artirarak zararli etki de gosterebilir. Bu calismada, istirahat halinde ve kollajenle uyarilmis trombositlerde akut yuksek glikozun trombosit agregasyonuna, oksidatif stres parametrelerine ve NO biyoyararlanimina etkileri arastirilmistir. Ayrica, kuersetin (superoksit anyon supurucusu) kullanilarak yuksek glikozun NO biyoyararlanimi uzerindeki etkilerinde superoksit uretiminin rolu incelenmistir. Yontemler: Yikanmis trombositler 5 mM D-glukoz (fizyolojik konsant¬rasyon, n:7) veya 25 mM D-glukoz (patofizyolojik konsantrasyon, n:7) veya kuersetin (10 μM) + 25 mM D-glukoz (n:7) ile 1 saat inkube edildi. Inkubasyon sonrasi, trombositlerde superoksit uretimi, lipid peroksidas¬yonu (LPO), NO, nitrotirozin (NT) duzeyleri ve ilerlemis glikasyon son urunleri (AGE) olculdu. Ayrica trombosit agregasyonu da incelendi. Bulgular: Dinlenme halinde ve kollajenle aktive trombositlerin yuksek glukoz ile inkubasyonu LPO, NT ve AGE duzeylerinde 5mM glukoz konsantrasyonuna gore istatistiksel olarak anlamli artislara neden oldu (p<0.05). Yuksek glukoz kollajenle aktive trombositlerde trombosit agregasyonunu, superoksit olusumunu ve NO duzeylerini anlamli olarak artirdi (p<0.05). Yuksek glukoz ile inkube edilen trombositlerde, kuer¬setin anlamli olarak NO uretiminin ve NO biyoyararlaniminin artmasina neden olurken oksidatif stresi baskiladi (p<0.05). Sonuc: Yuksek glukoz istirahat halinde ve ozellikle kollajen ile aktive trombositlerde oksidatif stresi arttirir ve NO biyoyararlanimini azaltir. Yuksek glukoz aracili superoksit uretiminin bu etkiler uzerinde rolu olabi¬lir. Bulgularimiz, diyabette trombosit-iliskili komplikasyonlarin onlenme¬sinde kuersetinin yararli etkisi olabilecegini gostermektedir.","PeriodicalId":16169,"journal":{"name":"Journal of Marmara University Institute of Health Sciences","volume":"17 1","pages":"239-246"},"PeriodicalIF":0.0,"publicationDate":"2015-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78684399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Factors That Correlated with Back Pain in Physiotherapists 与物理治疗师背部疼痛相关的因素

Journal of Marmara University Institute of Health Sciences Pub Date : 2015-12-29 DOI: 10.5455/MUSBED.20150831012038

Özge Çınar-Medeni, B. Elbasan, I. Duzgun, M. Kılınç

{"title":"The Factors That Correlated with Back Pain in Physiotherapists","authors":"Özge Çınar-Medeni, B. Elbasan, I. Duzgun, M. Kılınç","doi":"10.5455/MUSBED.20150831012038","DOIUrl":"https://doi.org/10.5455/MUSBED.20150831012038","url":null,"abstract":"Amac: Fizyoterapistlerde mesleki yuklenmelere bagli olarak bel agrisi siklikla gorulen bir durumdur. Bu calismanin amaci fizyoterapistlerde yas, vucut kitle indeksi, calisma posturu ve calisma yilinin bel agrisi ile ilgili ozurluluk duzeyi uzerine etkisini incelemektir. Yontem: Yirmi dokuz fizyoterapist calismaya dahil edildi. Calisma yili ve gunluk calisma saatleri kaydedildi. Olgularin bel agrisi ile ilgili sikâyetleri “Quebec Bel Agrisi Kisitlilik Olcegi” (QUEBEC) ile, calisma posturleri “Owako Calisma Posturu Analiz Sistemi” (OWAS) ile degerlendirildi. Bel agrisi ile yas, vucut kitle indeksi (VKI) , calisma posturu, calisma yili ve gunluk calisma saati arasindaki iliski Spearman korelasyon katsayisi kullanilarak incelendi. Bel agrisi olan ve olmayan fizyoterapistlerin yas, VKI, calisma yili, gunluk calisma saati ve calisma posturleri arasindaki fark Mann-Whitney U test ile degerlendirildi. Bulgular: QUEBEC skoru ile yas arasinda pozitif yonde orta derecede istatistiksel olarak anlamli iliski bulundu (r=0.44, p=0.01). Calisma yili ile calisma posturu (r=0.38, p=0.04) ve VKI (r=0.41, p=0.027) arasinda iliski oldugu goruldu. Bel agrisi olan ve olmayan fizyoterapistlerin yaslari istatistiksel olarak birbirinden farkli bulundu (p<0.05). Sonuclar: Calismamizda fizyoterapistlerde ilerleyen yasin bel agrisi ile ilgili ozurluluk duzeyini etkiledigi goruldu. Ayrica calisma yili arttikca calisma posturunun bozulmasi ve VKI’nin artmasinin bel agrisini tetikleyebilecek faktorler oldugu goruldu.","PeriodicalId":16169,"journal":{"name":"Journal of Marmara University Institute of Health Sciences","volume":"142 1","pages":"215-219"},"PeriodicalIF":0.0,"publicationDate":"2015-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73144674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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