journal of ilam university of medical sciences最新文献_第4页

The Effect of Acceptance and Commitment Therapy on Muscle Pain in Patients with Rheumatoid Arthritis 接受与承诺治疗对类风湿关节炎患者肌肉疼痛的影响

journal of ilam university of medical sciences Pub Date : 2022-06-01 DOI: 10.52547/sjimu.30.2.51

Soheyla Malek-Mohammadi-Memar, Mohammad Reza Zoghi Paydar

引用次数: 0

Effects of Eight Weeks of High-Intensity Interval Training on the Expression of the Nkx2.5 and Tbx5 Genes in the Heart Tissue of Type 2 Male Diabetic Rats 8周高强度间歇训练对2型雄性糖尿病大鼠心脏组织Nkx2.5和Tbx5基因表达的影响

journal of ilam university of medical sciences Pub Date : 2022-06-01 DOI: 10.52547/sjimu.30.2.71

M. Kousha, Hossein Abednatanzi, M. Gholami, F. Ghazalian

{"title":"Effects of Eight Weeks of High-Intensity Interval Training on the Expression of the Nkx2.5 and Tbx5 Genes in the Heart Tissue of Type 2 Male Diabetic Rats","authors":"M. Kousha, Hossein Abednatanzi, M. Gholami, F. Ghazalian","doi":"10.52547/sjimu.30.2.71","DOIUrl":"https://doi.org/10.52547/sjimu.30.2.71","url":null,"abstract":"Introduction: Exercise and antioxidants consumption are known as protective effect against the risk of diabetes. Therefore, the current study aimed to investigate the effects of eight weeks of high-intensity interval training (HIIT) and thyme honey on the expression of Nkx2.5 and Tbx5 genes in the heart tissue of male type 2 diabetic rats. Material & Methods: This experimental study was performed on 36 male diabetic rats which were randomly divided into four groups of control (n=8), HIIT (n=10), thyme honey (n=8), and HIIT+thyme honey (n=10). The HIIT training intervention was conducted in eight weeks (five sessions per week) and included 2 to 8 intervals with 2 min running at 80%-90% VO2max and 1 min at 50%-56% VO2max. Additionally, the supplement groups consumed 3 g/kg of thyme honey, 5 days/week. Both Nkx2.5 and Tbx5 gene expression in heart tissue were measured using real-time RT-PCR. To evaluate the differences among the groups, ANOVA and LSD post hoc tests were used at the significance level of P≤0.05. (Ethic code: IR.SSRC.REC.1399.080) Findings: The results revealed that the expression of the Nkx2.5 gene was significantly increased only in the HIIT group, compared to the control group (P=0.03); however, it was not observed in other intervention groups (P>0.05). The expression of the Tbx5 gene was significantly increased in both HIIT (P=0.02) and HIIT+thyme honey (P=0.02) groups, compared to the control group. Discussion & Conclusion: The HIIT is associated with increased expression of the Nkx2.5 and Tbx5 genes in the heart tissue of diabetic rats; however, it can not be said exactly that thyme honey has similar effects in diabetic rats.","PeriodicalId":16041,"journal":{"name":"journal of ilam university of medical sciences","volume":"211 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80662682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Effectiveness of Acceptance and Commitment Therapy (ACT) and Compassion-Focused Therapy (CFT) on Internalized Shame in Patients with Vitiligo 接受与承诺疗法(ACT)与同情疗法(CFT)治疗白癜风患者内化羞耻感的效果比较

journal of ilam university of medical sciences Pub Date : 2022-06-01 DOI: 10.52547/sjimu.30.2.82

M. Solimanpour, A. Pirkhaefi, K. Zahrakar

{"title":"Comparison of Effectiveness of Acceptance and Commitment Therapy (ACT) and Compassion-Focused Therapy (CFT) on Internalized Shame in Patients with Vitiligo","authors":"M. Solimanpour, A. Pirkhaefi, K. Zahrakar","doi":"10.52547/sjimu.30.2.82","DOIUrl":"https://doi.org/10.52547/sjimu.30.2.82","url":null,"abstract":"Introduction: Skin diseases, not only may have physical consequences but also costly psychological consequences in one’s life. The present study was conducted to compare the effect of group counseling with the approaches of Compassion-Focused Therapy (CFT) and Acceptance and Commitment Therapy (ACT) on the internalized shame of patients with vitiligo. Material & Methods: This was a quasi-experimental study with pre-test and post-test design and follow-up and control groups. The study population consisted of all women with vitiligo who were referred to Razi Hospital, in Tehran, in 1399. A total of 45 persons who met the inclusion criteria were purposefully selected and randomly divided into 3 groups of 15 people each (two experimental groups and one control group). The study tool included Cook's Internalized Shame Scale (1993). Descriptive statistics and repeated measures analysis of variance was used to test the research hypotheses. The data were analyzed using SPSS software (version 20). (Ethic code: R.IAU.SRB.REC.1399.125) Findings: Both CFT and ACT therapeutic approaches were effective in reducing internalized shame in patients with vitiligo, compared to the control group. A comparison of the two approaches showed no significant differences between the two experimental groups of CFT and ACT in terms of all components of shyness, self-esteem, and internalized shame. Discussion & Conclusion: Based on the obtained results, the above-mentioned treatments can be used to improve the psychological status of patients with vitiligo.","PeriodicalId":16041,"journal":{"name":"journal of ilam university of medical sciences","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84277549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Role of Experiential Avoidance and Alexithymia in the Prediction of Psychosomatic Disorder among the Employees at National Iranian South Oil Company 伊朗国家南方石油公司员工体验性回避和述情障碍在心身障碍预测中的作用

journal of ilam university of medical sciences Pub Date : 2022-06-01 DOI: 10.52547/sjimu.30.2.63

Ali Molaei pardh, J. Karami, Asieh Moradi

{"title":"Role of Experiential Avoidance and Alexithymia in the Prediction of Psychosomatic Disorder among the Employees at National Iranian South Oil Company","authors":"Ali Molaei pardh, J. Karami, Asieh Moradi","doi":"10.52547/sjimu.30.2.63","DOIUrl":"https://doi.org/10.52547/sjimu.30.2.63","url":null,"abstract":"Introduction: Psychosomatic disorder is one of the most common mental disorders in which meaningful psychological events play an effective role. This study aimed to investigate the role of experiential avoidance and alexithymia in the prediction of psychosomatics disorder among the employees at the national Iranian south oil company. Material & Methods: The statistical population of this descriptive correlational study included all employees at the national Iranian south oil company from 2020 to 2021. The sample size of the present study was obtained at 371 people based on Cochran's formula. Due to the possibility of incomplete questionnaires, 418 employees were selected by the available sampling method. They were then requested to complete the Symptom Checklist-90 (SCL-90), experiential avoidance (AAQ), and alexithymia (FTAS-20). (Ethic code: 140090) Findings: The results of the Pearson correlation coefficient showed a correlation coefficient of 0.39 between experiential avoidance and psychosomatic disorder which was significant at 0.001. Moreover, there was a correlation coefficient of 0.15 between alexithymia and psychosomatic disorder, which was significant at 0.003. In addition, the results of linear regression analysis showed that experiential avoidance could predict psychosomatic disorders. Discussion & Conclusion: Therefore, according to the findings, in order to reduce psychosomatic disorders, it is necessary to conduct interventions on psychological flexibility and emotional expression. Finally, it is suggested that other empirical and quasi-experimental studies be conducted to confirm these results.","PeriodicalId":16041,"journal":{"name":"journal of ilam university of medical sciences","volume":"147 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78133841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of Human Albumin Protein Interaction with Fluorouracil Anticancer Drug Using Molecular Docking Method 人白蛋白与氟尿嘧啶抗癌药物相互作用的分子对接研究

journal of ilam university of medical sciences Pub Date : 2022-06-01 DOI: 10.52547/sjimu.30.2.32

Mohammad Motaharinia, Mahdieh Sadeghpour, M. Shalbafan

引用次数: 0

Explaining the Effective Dimensions and Components for Community-Based Medical Education from the Perspective of Family Physicians of Ilam University of Medical Sciences: A Qualitative Study 从伊拉姆医科大学家庭医生的角度解释社区医学教育的有效维度和成分:一项定性研究

journal of ilam university of medical sciences Pub Date : 2022-06-01 DOI: 10.52547/sjimu.30.2.8

Zohreh sadat Mirmoghtadaaie, S. Ahmady, Hojjatolah Abdoullahi

引用次数: 0

Editing of the MALAT1 Gene in MDA-MB-361 Breast Cancer Cell Line using the Novel CRISPR Method 利用新型CRISPR方法编辑MDA-MB-361乳腺癌细胞系MALAT1基因

journal of ilam university of medical sciences Pub Date : 2022-06-01 DOI: 10.52547/sjimu.30.2.18

Soraya Ahmadi-Baloutaki, A. Doosti, Mojtaba Jaafarinia, H. Goudarzi

{"title":"Editing of the MALAT1 Gene in MDA-MB-361 Breast Cancer Cell Line using the Novel CRISPR Method","authors":"Soraya Ahmadi-Baloutaki, A. Doosti, Mojtaba Jaafarinia, H. Goudarzi","doi":"10.52547/sjimu.30.2.18","DOIUrl":"https://doi.org/10.52547/sjimu.30.2.18","url":null,"abstract":"The expression of genes related to apoptosis was analyzed by Real-Time PCR. Cell proliferation and apoptosis were assessed by MTT and flow cytometry methods, respectively. (Ethic code: IR.IAU.M.REC.1399.010) Findings: The MALAT1 gene was edited by the CRISPR method in MDA-MB-361 cells. The rate of cell proliferation in the cells of the treatment group, compared to the control groups, showed a significant decrease (P<0.05). Apoptosis levels were significantly increased in cancer cells the MALAT1 gene of which had been deleted. Moreover, the expression of BCL2 and survivin anti-apoptotic genes in treated (edited) cells was significantly reduced, compared to control cells (P<0.05). Increased expression of proapoptotic genes P53, BAK, BAX, and FAS was also observed in the edited cells (P<0.05). Discussion & Conclusion: The results of this study confirm that the deletion of the MALAT1 gene has a significant effect on increasing apoptosis and reducing cell proliferation. A reduction in the expression of the MALAT1 gene can prevent the growth and proliferation of breast cancer cell lines. Therefore, it seems that the control of MALAT1 oncogene expression is useful and effective for controlling tumors.","PeriodicalId":16041,"journal":{"name":"journal of ilam university of medical sciences","volume":"121 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80193756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Antimicrobial Effects of Aqueous-Alcoholic Extract of Artemisia Turanica against Methicillin-Resistant Staphylococcus aureus (MRSA): An in vitro Study 图兰蒿水醇提取物对耐甲氧西林金黄色葡萄球菌(MRSA)抗菌作用的体外研究

journal of ilam university of medical sciences Pub Date : 2022-06-01 DOI: 10.52547/sjimu.30.2.1

Hasan Bagheri yazdi, Hamed Norouzi taheri

引用次数: 1

Synergistic Effect of Silver Nanoparticles and Streptomycin Antibiotic on the MexX Gene Expression of Pump Efflux System in Drug-Resistant Pseudomonas aeruginosa Strains 纳米银与链霉素对耐药铜绿假单胞菌泵外系统MexX基因表达的协同作用

journal of ilam university of medical sciences Pub Date : 2022-06-01 DOI: 10.52547/sjimu.30.2.41

A. Mohammad, Farahnaz - Molavi, S. Dolatabadi

引用次数: 1

Relationship of Bacteria Isolated from Antral Gastric Biopsy with the Incidence of Dyspepsia in Patients Referred to Mehrad and Labbafinejad Hospitals, Tehran, Iran, in 2018 2018年伊朗德黑兰Mehrad和Labbafinejad医院转诊患者胃窦活检分离细菌与消化不良发生率的关系

journal of ilam university of medical sciences Pub Date : 2022-03-01 DOI: 10.52547/sjimu.30.1.85

Mahnaz Mohammadi, A. Talebi Bezmin abadi, F. Rahimi, M. Forootan

引用次数: 0