Journal of Guilan University of Medical Sciences最新文献_第4页

Post-Traumatic Stress Disorder, Anxiety Sensitivity, and Resilience Among Hospital Medical Staff in Rasht, During the COVID-19 Pandemic 2019冠状病毒病大流行期间拉什特医院医务人员的创伤后应激障碍、焦虑敏感性和复原力

Journal of Guilan University of Medical Sciences Pub Date : 2023-01-01 DOI: 10.32598/jgums.31.3.1673.3

M. Baradaran, Maedeh Mirzaei Malati, Roghayeh Etemadifar, Samaneh Kouchak Asaadi, Nasrin Parsamehr

{"title":"Post-Traumatic Stress Disorder, Anxiety Sensitivity, and Resilience Among Hospital Medical Staff in Rasht, During the COVID-19 Pandemic","authors":"M. Baradaran, Maedeh Mirzaei Malati, Roghayeh Etemadifar, Samaneh Kouchak Asaadi, Nasrin Parsamehr","doi":"10.32598/jgums.31.3.1673.3","DOIUrl":"https://doi.org/10.32598/jgums.31.3.1673.3","url":null,"abstract":"Background The coronavirus disease 2019 (COVID-19) pandemic has extensively affected the public physical and mental health, especially the medical staff working in the COVID-19 wards of hospitals. Objective This study aims to evaluate the relationship between post-traumatic stress disorder (PTSD), anxiety sensitivity (AS), and resilience among hospital medical staff in Rasht, during the COVID-19 pandemic. Methods This is an analytical cross-sectional study. The study population consists of all medical staff working in the COVID-19 wards of Poursina and Razi hospitals in Rasht, Iran. Of these, 94 participated who were selected using a convenience sampling method. Weathers et al.’s post-traumatic stress disorder checklist, Reiss et al.’s AS index, and Connor-Davidson resilience scale were used for data collection. The data were analyzed using Pearson correlation test and multiple linear regression analysis. Results There was a significant negative correlation between PTSD and resilience (r‌=‌-0.405, P‌=‌0.001). and a significant positive correlation between PTSD and AS (r=0.633, P=0.001). The results of multiple analyses showed that resilience (B=-0.208, P=0.004) and AS (B=0.574, P=0.001) could significantly explain the PTSD in medical staff. Conclusion Resilience can be an important protective factor against PTSD in hospital medical staff during the COVID-19 pandemic. The medial staff with AS may experience the symptoms of PTSD more.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"116 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80646989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fabrication of Clotrimazole Microparticles Using Polyethylene Glycol 6000 and Beeswax 聚乙二醇6000和蜂蜡制备氯霉唑微粒

Journal of Guilan University of Medical Sciences Pub Date : 2023-01-01 DOI: 10.32598/jgums.31.3.1928.1

Kobra Najafzadeh Mahvizani, Marjan Daeihamed, Gita Alkan Saberi, Z. Hesari

{"title":"Fabrication of Clotrimazole Microparticles Using Polyethylene Glycol 6000 and Beeswax","authors":"Kobra Najafzadeh Mahvizani, Marjan Daeihamed, Gita Alkan Saberi, Z. Hesari","doi":"10.32598/jgums.31.3.1928.1","DOIUrl":"https://doi.org/10.32598/jgums.31.3.1928.1","url":null,"abstract":"Background Microparticles are one of drug delivery systems designed for sustained and controlled release of drugs for a long period of time. Clotrimazole is a broad-spectrum antifungal agent, which is generally used for treatment of Candida albicans and others fungal infections. Objective The present study aims to fabricate Clotrimazole microparticles using beeswax (lipophilic coating) and polyethylene glycol (hydrophilic coating). Methods In this study, Clotrimazole microparticles by polyethylene glycol (PEG 6000) and beeswax were prepared using spray drying technique. Morphology and size of the microparticles were assessed using optical microscopy and scanning electron microscopy. Particle size analyses were performed using Zetasizer technique. The drug release rate was measured using ultraviolet-visible spectroscopy. To study the interactions between microparticles and carriers, Fourier transform infrared spectroscopy (FTIR) was used. Results Size of the microparticles was below 1000 µm. The microparticles prepared from beeswax and PEG 6000 had quasicrystalline and crystalline morphologies, respectively. The maximum drug release rate in 6 hours was 80.53% in formulation F3 (microparticles prepared by beeswax) and 79.29 in formulation F6 (microparticles prepared by PEG 6000). The FTIR results showed probable interactions between clotrimazole microparticles and beeswax. Conclusion Both beeswax and PEG 6000 polymers result in similar rate of drug release; however, since beeswax has interactions with clotrimazole, PEG 600 formulation seems to be more appropriate for fabrication of clotrimazole microparticles.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80726881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimization of Xanthan Gum and Sorbitol Levels in the Mycophenolate Mofetil Powder for Oral Suspension 口腔混悬剂霉酚酸酯粉末中黄原胶和山梨醇含量的优化

Journal of Guilan University of Medical Sciences Pub Date : 2023-01-01 DOI: 10.32598/jgums.31.3.2014.2

Amin Umrani, H. Faghihi, Z. Mohammadi, P. Mirzabeigi, Hamed Montazeri Ghods, A. Rastegari

{"title":"Optimization of Xanthan Gum and Sorbitol Levels in the Mycophenolate Mofetil Powder for Oral Suspension","authors":"Amin Umrani, H. Faghihi, Z. Mohammadi, P. Mirzabeigi, Hamed Montazeri Ghods, A. Rastegari","doi":"10.32598/jgums.31.3.2014.2","DOIUrl":"https://doi.org/10.32598/jgums.31.3.2014.2","url":null,"abstract":"Background Mycophenolate mofetil as an immunosuppressive agent is widely administered in patients with kidney disorders and following organ transplantation. The amounts of xanthan gum and sorbitol, as two excipients of mycophenolate mofetil, are influential on the final quality and stability of the suspension. Objective In this experimental study, we aim to optimize the levels of xanthan gum and sorbitol in the Mycophenolate mofetil powder. Methods A Central composite design was used to prepare the formulations. The amounts of xanthan gum and sorbitol were considered as independent variables while the sedimentation volume (F value) and concentration of active pharmaceutical ingredient (API) after preparation and after 3 months of storage at 45 ͦC were considered as dependent variables. The samples were prepared through wet granulation process. Chromatography analysis and determination of F value and API were then performed. Results Analysis of variance showed that the increase in the amounts of xanthan up to 75 mg provided higher F value and better protection of API after 3 months by 98%, while the increase of sorbitol from 10 to 25 g had no significant effect on these variables. Optimized sample composed of 16.69 g sorbitol and 68.81 mg xanthan gum. Predicted error was desirably less than 5%. Conclusion The proposed formulation of mycophenolate mofetil powder for oral suspension with optimum amounts of xanthan gum and sorbitol has good stability. High level of xanthan gum and moderate level of sorbitol are recommended for preparing an optimal product.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82152932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and Type of Dental Abnormalities Among Patients With Different Skeletal Malocclusion Classes in Northern Iran 伊朗北部不同骨骼错颌患者牙畸形的患病率和类型

Journal of Guilan University of Medical Sciences Pub Date : 2023-01-01 DOI: 10.32598/jgums.31.3.1942.1

Negar Khosravifard, F. Gholinia, Farzaneh Ostovarrad, Zahra Dalili Kajan, Hamideh Mohammadi, Parmida Farzam

{"title":"Prevalence and Type of Dental Abnormalities Among Patients With Different Skeletal Malocclusion Classes in Northern Iran","authors":"Negar Khosravifard, F. Gholinia, Farzaneh Ostovarrad, Zahra Dalili Kajan, Hamideh Mohammadi, Parmida Farzam","doi":"10.32598/jgums.31.3.1942.1","DOIUrl":"https://doi.org/10.32598/jgums.31.3.1942.1","url":null,"abstract":"Background Dental abnormalities are considered important, since they cause aesthetic and functional problems for people. Orthodontic treatment becomes more complicated when craniofacial abnormalities are accompanied with dental abnormalities. Objective This study aims to compare the frequency and type of dental abnormalities among patients with different skeletal malocclusion classes in northern Iran in terms of age and gender. Methods Participants were 310 patients (32.9% Class I, 33.9% Class II, and 33.2% Class III). They were evaluated with respect to hypodontia, hyperdontia, impaction, microdontia, macrodontia, and dens invaginatus/evaginatus. Association of the prevalence of dental abnormalities with the type of malocclusion and gender was assessed by chi-square test and Fisher’s exact test, while independent t-test was used to determine its association with age. Results The overall frequency of dental abnormalities was 33%. Class III patients had the highest rate of dental abnormalities (40.8%); however, the difference was not statistically significant (P=0.105). Hypodontia and impacted teeth were the most frequent abnormalities in all malocclusion groups. Occurrence of tooth impaction differed significantly among the three malocclusion groups (P<0.001), where the highest rate belonged to the class III group. Hypodontia was more frequent in males (P=0.040). Tooth impaction and microdontia were the two abnormalities that showed significant association with age (P<0.05). Conclusion Dental abnormalities in northern Iran is more prevalent among people with the skeletal class III malocclusion. The prevalence of some dental abnormalities is associated with gender and age.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80453905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing the Mean Platelet Volume and the Neutrophil-to-Lymphocyte Ratio in Children With Bacterial Pneumonia Associated With or Without Pleural Empyema 合并或不合并胸膜脓胸的细菌性肺炎患儿平均血小板体积和中性粒细胞/淋巴细胞比值的比较

Journal of Guilan University of Medical Sciences Pub Date : 2023-01-01 DOI: 10.32598/jgums.31.3.1813.1

H. Hashemian, Fina Sanati

{"title":"Comparing the Mean Platelet Volume and the Neutrophil-to-Lymphocyte Ratio in Children With Bacterial Pneumonia Associated With or Without Pleural Empyema","authors":"H. Hashemian, Fina Sanati","doi":"10.32598/jgums.31.3.1813.1","DOIUrl":"https://doi.org/10.32598/jgums.31.3.1813.1","url":null,"abstract":"Background Pneumonia is one of the severe infections in children, and empyema is one of its essential complications which causes more risk in affected children. Therefore, its early diagnosis is of great importance. Objective This study aims to compare the value of two inflammatory markers including mean platelet volume (MPV) and neutrophil-to-lymphocyte ratio (NLR) in children with pneumonia associated with and without pleural empyema. Methods This study was conducted on the data of 128 children aged 3 months to 14 years with bacterial pneumonia associated with pleural empyema and 128 children without pleural empyema. The MPV and NLR values and the patients’ demographic and clinical characteristics were analyzed in SPSS software version 18 software. The confidence interval for the area under the ROC curve was calculated using binomial exact method. The significance level was set at 0.05. Results Of 256 children, 42.2% were girls, and most of children had ages <3 years (35.2%). Children with empyema had significantly higher NLR, platelet count, and MPV than children without empyema (P=0.040, 0.005, and 0.021, respectively). The MPV (P=0.020) and NLR (P=0.039) were significant predictors of empyema. Conclusion The use of NLR and MPV may be useful in the early diagnosis of empyema in children with pneumonia.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84582928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiological Study of Different Types of Cancers Among Adults PERSIAN Guilan Cohort Study 成人不同类型癌症的流行病学研究波斯桂兰队列研究

Journal of Guilan University of Medical Sciences Pub Date : 2023-01-01 DOI: 10.32598/jgums.31.3.1748.5

H. A. Balou, F. Joukar, S. Yeganeh, Soheil Hassanipour, M. Naghipour, Massood Baghaee, G. Sadeghi, Golsa Hayadokht, Hossein-Ali Nikbakht, F. Mansour-Ghanaei

{"title":"Epidemiological Study of Different Types of Cancers Among Adults PERSIAN Guilan Cohort Study","authors":"H. A. Balou, F. Joukar, S. Yeganeh, Soheil Hassanipour, M. Naghipour, Massood Baghaee, G. Sadeghi, Golsa Hayadokht, Hossein-Ali Nikbakht, F. Mansour-Ghanaei","doi":"10.32598/jgums.31.3.1748.5","DOIUrl":"https://doi.org/10.32598/jgums.31.3.1748.5","url":null,"abstract":"Background Cancer is the leading cause of death in the world after cardiovascular disease, and is the third leading cause of death in Iran. Objective This epidemiological study aims to investigate different types of cancers in Sowme’e Sara County, Guilan, Iran. Methods This analytical cross-sectional study is a part of the PERSIAN Guilan cohort study that was conducted on 10520 adult men and women in Sowme’e Sara County. The prevalence rate was determined per 100,000 people. Descriptive statistics (mean, standard deviation, frequency, and percentage) were used for describing data. Statistical analyzes were performed in STATA version 13 software. Results In this study, 94 patients with cancer and 98 types of cancer were recorded. Most of patients were female (n=65, 68.4%). The mean age at diagnosis in men and women was 47.61±11.23 and 44.30±7.87 years, respectively (Total=45.58±10.09 years). The most common cancers were breast cancer, brain & central nervous system cancer, and prostate cancer. The minimum age for diagnosis in men and women were 23 and 19 years, respectively,. Conclusion Screening for breast cancer in women and prostate cancer in men living in Sowme’e Sara County should be done which is currently underway using mammography and prostate specific antigen tests.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83290924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vascular Endothelial Growth Factor Level in Patients With Oral Lichen Planus: A Systematic Review and Meta-Analysis 口腔扁平苔藓患者血管内皮生长因子水平:系统回顾和荟萃分析

Journal of Guilan University of Medical Sciences Pub Date : 2022-10-01 DOI: 10.32598/jgums.31.3.1947.1

M. Jazaeri, H. Abdolsamadi, S. Khazaie, L. Shahabi

{"title":"Vascular Endothelial Growth Factor Level in Patients With Oral Lichen Planus: A Systematic Review and Meta-Analysis","authors":"M. Jazaeri, H. Abdolsamadi, S. Khazaie, L. Shahabi","doi":"10.32598/jgums.31.3.1947.1","DOIUrl":"https://doi.org/10.32598/jgums.31.3.1947.1","url":null,"abstract":"Background According to the possible role of vascular endothelial growth factor (VEGF) in the incidence of oral lichen planus (OLP) lesions, it seems necessary to evaluate this factor in patients with OLP. Objective The present study aims to investigate the level of VEGF in patients with OLP. Methods In this systematic review and meta-analysis, the search was conducted in online databases, including PubMed, Web of Science, and Scopus. The data were analyzed in the Stata v. 14 software at a 95% confidence interval (CI) and using a random effect model. The standardized mean difference was used to measure the difference in VEGF level between the two groups of control and OLP. The data heterogeneity was quantified by the I2 index. Results There was no significant difference between the two groups in terms of VEGF (SD=0.46, 95% CI: -2.13, -3.05, P=0.730) and the I2 index showed significant heterogeneity among the results of the studies (I2=97.9%). Based on the results of the immunohistochemistry, there was a significant difference in the VEGF level between the two groups (SD=3.30, 95% CI: 6.25, -0.36); however, the difference between the two groups was not statistically significant via the ELISA method (P=0.530). Conclusion The VEGF level in patients with OLP is higher compared to healthy people. Therefore, the serum factors which indicate VEGF should be considered an effective risk factor for OLP.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84457011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Resistance Aerobic Training on the Expression of SEMA3A and NCAM Genes and Proteins in the Soleus Muscle of Male Rats in Different Age Groups 阻力有氧训练对不同年龄组雄性大鼠比目鱼肌SEMA3A和NCAM基因及蛋白表达的影响

Journal of Guilan University of Medical Sciences Pub Date : 2022-10-01 DOI: 10.32598/jgums.31.3.1846.1

Mohammad Mahdi Bagherpour Tabalvandani, M. F. Fadaei Chafy, A. Elmieh

{"title":"Effects of Resistance Aerobic Training on the Expression of SEMA3A and NCAM Genes and Proteins in the Soleus Muscle of Male Rats in Different Age Groups","authors":"Mohammad Mahdi Bagherpour Tabalvandani, M. F. Fadaei Chafy, A. Elmieh","doi":"10.32598/jgums.31.3.1846.1","DOIUrl":"https://doi.org/10.32598/jgums.31.3.1846.1","url":null,"abstract":"Background Exercise and physical activity improve damage and destructive changes in the peripheral nervous system. Objective This study aims to investigate the effects of resistance aerobic training on the expression of SEMA3A and NCAM genes and proteins of soleus muscle in male rats of different age groups. Methods A total of 30 male Wistar rats in three groups of 2-week-old (infant) (n=10), 6-week-old (young) (n=10), and 96-week-old (elderly) (n=10) were divided into two groups of training and control. The training program included 6 days of resistance and aerobic training one day in between. The rats were euthanized and the soleus muscle was extracted 48 h after the last training session. A fluorescent microscope was used to measure SEMA3A and NCAM proteins in muscle fibers. Gene expressions were measured by real-time polymerase chain reaction. Results The results showed that SEMA3A gene expression was not significantly different between exercise and control groups in all three age groups; however, SEMA3A protein expression was significantly reduced in infant and young exercise groups (P≤0.001). Also, NCAM gene expression was not significantly different between training and control groups in all three age groups; while there was a significant decrease in NCAM protein expression in young and old training groups compared to the control group (P≤0.001). Conclusion The results showed that resistance aerobic training can inhibit the process of peripheral nerve damage in infant and young rats, as well as the growth and strength of the neuromuscular junction in young and elderly rats.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86480991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hemodynamic Status in Electroconvulsive Therapy Patients 电休克治疗患者的血流动力学状态

Journal of Guilan University of Medical Sciences Pub Date : 2022-10-01 DOI: 10.32598/jgums.31.3.1329.4

R. Soleimani, Samaneh Ghazanfar Tehran, Habib Eslami Kenarsari, Batul Montazery, Samin Khoshnoud Speily, Samira Mirzababaei, Fatemeh Baghernezhad, Ebrahim Haddad Komleh, Gelareh Biazar, Sahar Erabi

{"title":"Hemodynamic Status in Electroconvulsive Therapy Patients","authors":"R. Soleimani, Samaneh Ghazanfar Tehran, Habib Eslami Kenarsari, Batul Montazery, Samin Khoshnoud Speily, Samira Mirzababaei, Fatemeh Baghernezhad, Ebrahim Haddad Komleh, Gelareh Biazar, Sahar Erabi","doi":"10.32598/jgums.31.3.1329.4","DOIUrl":"https://doi.org/10.32598/jgums.31.3.1329.4","url":null,"abstract":"Background Electroconvulsive therapy (ECT) is a safe and practical treatment method for patients with severe, refractory, or emergency psychiatric disorders. However, ECT is often associated with hemodynamic fluctuations. Objective This study aims to investigate the patterns of hemodynamic changes in patients undergoing ECT. Methods This longitudinal study was conducted in Shafa Hospital, a referral and academic center in Rasht City, Iran, in 2020. The hemodynamic parameters, including heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP) were recorded before the induction of anesthesia (T0), 1 min after the induction of anesthesia (T1), 1 min after the seizure (T2), and 15 min after the wakefulness (T3). The trend of changes of these parameters was compared in the above-mentioned time intervals. Results The data from 126 patients were analyzed. Most of the cases were diagnosed with a psychotic disorder of schizophrenia (59.5%) and a minority had major depression (14.3%). Meanwhile, 15.9% of the patients suffered from comorbidities. In terms of SBP, DBP, and MAP, the trend of changes was significant (P=0.0001) at four measurement point times, but this was not true for HR (P=0.74). However, all changes in the hemodynamic parameters were kept in the normal range. Conclusion Our study showed that despite the fluctuations in the hemodynamic parameters during ECT, patient management was acceptable as a result of the teamwork and appropriate interaction of psychiatric and anesthesia teams.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89706557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Repeatability and Reproducibility of Macular Thickness Measurements Using Optical Coherence Tomography (OCT) in Normal Eyes Before and After Pupil Dilation 光学相干断层扫描(OCT)在瞳孔扩张前后正常眼黄斑厚度测量的可重复性和再现性

Journal of Guilan University of Medical Sciences Pub Date : 2022-10-01 DOI: 10.32598/jgums.31.3.1911.1

Yousef Alizadeh, Maryam Dourandeesh, Hassan Behboudi, S. Kianmehr, Ehsan Kazemnezhad Leyli, Nooshin Nimasa

{"title":"Repeatability and Reproducibility of Macular Thickness Measurements Using Optical Coherence Tomography (OCT) in Normal Eyes Before and After Pupil Dilation","authors":"Yousef Alizadeh, Maryam Dourandeesh, Hassan Behboudi, S. Kianmehr, Ehsan Kazemnezhad Leyli, Nooshin Nimasa","doi":"10.32598/jgums.31.3.1911.1","DOIUrl":"https://doi.org/10.32598/jgums.31.3.1911.1","url":null,"abstract":"Background Optical coherence tomography (OCT) is one of the most valuable imaging techniques in the evaluation of macula. The repeatability and reproducibility of OCT are of crucial importance in reassuring this tool’s efficacy in evaluating the structure of the retina. Objective This study aims to investigate the repeatability and reproducibility of OCT in measuring the macular thickness in normal eyes before and after pupil dilation. Methods A total of 44 eyes of healthy individuals in the age range of 20 to 50 years were employed for the measurement of macular thickness in the central 6 mm using the Cirrus SD-OCT tool. Results According to ICC, the repeatability of macular thickness was 0.95 (95% CI, 0.95 - 0.96). The mean macular thickness before and after pupil dilation was statistically significant in the nasal quadrant of the outer 6 mm ring (N2) and the inferior quadrant of the outer 6 mm ring (I2) (P=0.0001). The highest repeatability before and after pupil dilation was seen in the nasal quadrant of the inner 3 mm ring (N1) and the central ring (C), respectively. Conclusion This study shows that measuring the macular thickness using the Spectral domain cirrus OCT (SD-OCT) has acceptable repeatability and reproducibility. Since the absolute value of the mean difference between the three measurements in the N2 and I2 regions was statistically significant, using a single method (i.e., whether to apply the eye drop) is preferable for follow-ups in cases where the measurements are needed within 3 to 6 mm in center of the macula.","PeriodicalId":15994,"journal":{"name":"Journal of Guilan University of Medical Sciences","volume":"164 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74317891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0