Journal of Family and Reproductive Health最新文献

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Recurrent Dermatofibrosarcoma Protuberans of the Vulva: A Rare Occurrence and Review of Literature. 外阴隆突性皮肤纤维肉瘤复发:罕见病例及文献回顾。
Journal of Family and Reproductive Health Pub Date : 2021-06-01 DOI: 10.18502/jfrh.v15i2.6456
Lajya Devi Goyal, Priyanka Garg, Manmeet Kaur, Diksha Sharma
{"title":"Recurrent Dermatofibrosarcoma Protuberans of the Vulva: A Rare Occurrence and Review of Literature.","authors":"Lajya Devi Goyal,&nbsp;Priyanka Garg,&nbsp;Manmeet Kaur,&nbsp;Diksha Sharma","doi":"10.18502/jfrh.v15i2.6456","DOIUrl":"https://doi.org/10.18502/jfrh.v15i2.6456","url":null,"abstract":"<p><p><b>Objective:</b> Dermatofibrosarcoma protuberans (DFSP) of the vulva is an uncommon soft tissue tumor with fewer than 60 cases reported previously. Distant metastasis is rare with a high propensity for local invasion. Surgical management is the gold standard with adequate margin excision to prevent future recurrences. We report a case of vulvar DFSP requiring three resections to achieve primary clearance. To the best of our knowledge, this is the first case report from India. <b>Case report</b> <b>:</b> A 35-years-old female, presented with nodular vulvar mass for the third time arising from the upper part of right labia majora for the last year. She had a history of two similar episodes in the past for which excision was done and histopathology confirmed DFSP. The third wide local resection was performed with 3 cm margins and the margins were sent for intra-operative frozen section analysis, which was confirmed clear by the pathologist. The patient has been free of recurrence for two years. <b>Conclusion:</b> DFSP is a challenging condition presenting as a non-tender nodular mass characterized by local invasion and recurrence. Early diagnosis and appropriate management using wide local excision with accurate margin assessment can achieve optimal results and prevent future recurrences.</p>","PeriodicalId":15845,"journal":{"name":"Journal of Family and Reproductive Health","volume":"15 2","pages":"136-140"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f2/43/JFRH-15-136.PMC8520659.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39832634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Endometrial Serous Carcinoma Arising From Adenomyosis: A Clinico-Pathological Insight. 子宫腺肌病引起的子宫内膜浆液性癌:临床病理观察。
Journal of Family and Reproductive Health Pub Date : 2021-06-01 DOI: 10.18502/jfrh.v15i2.6454
Amrita Talwar, Pushpanjali Behera, Arvind Ahuja, Bani Sarkar, Ravi Hari Phulware
{"title":"Endometrial Serous Carcinoma Arising From Adenomyosis: A Clinico-Pathological Insight.","authors":"Amrita Talwar,&nbsp;Pushpanjali Behera,&nbsp;Arvind Ahuja,&nbsp;Bani Sarkar,&nbsp;Ravi Hari Phulware","doi":"10.18502/jfrh.v15i2.6454","DOIUrl":"https://doi.org/10.18502/jfrh.v15i2.6454","url":null,"abstract":"<p><p><b>Objective:</b> Endometrial cancer (EC) is the most commonly diagnosed malignancy and has the second-highest mortality rate among gynecological cancers. Adenomyosis is well-known for abnormal uterine bleeding and is a widely reported entity; however, an EC arising from the adenomyosis is a rare event; even rarer is the occurrence of serous endometrial carcinoma. <b>Case report</b> <b>:</b> A 60-year post-menopausal female presented with post-menopausal bleeding. Subsequently, she underwent a hysterectomy, which showed atrophic and cystic endometrium with extensive adenomyosis and atypical endometrial glands, which are diffusely P53 positive with intervening negative benign and focally positive dysplastic endometrial glands. A final diagnosis of serous endometrial carcinoma arising from adenomyosis was rendered. In a table format, previously reported serous endometrial carcinoma Arising cases from adenomyosis using PubMed search had been described. <b>Conclusion:</b> Serous endometrial carcinoma arising from adenomyosis (<20 cases reported) and has a slightly more dismal prognosis than those deriving from the endometrial cavity. Hence, this case report highlights the occurrence, rarity, and importance of such an entity.</p>","PeriodicalId":15845,"journal":{"name":"Journal of Family and Reproductive Health","volume":"15 2","pages":"125-129"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/55/3b/JFRH-15-125.PMC8520663.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39832632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Systematic Review on Use of Medicinal Plants for Male Infertility Treatment. 药用植物治疗男性不育症的系统综述。
Journal of Family and Reproductive Health Pub Date : 2021-06-01 DOI: 10.18502/jfrh.v15i2.6447
Nasibeh Roozbeh, Azam Amirian, Fatemeh Abdi, Simin Haghdoost
{"title":"A Systematic Review on Use of Medicinal Plants for Male Infertility Treatment.","authors":"Nasibeh Roozbeh,&nbsp;Azam Amirian,&nbsp;Fatemeh Abdi,&nbsp;Simin Haghdoost","doi":"10.18502/jfrh.v15i2.6447","DOIUrl":"https://doi.org/10.18502/jfrh.v15i2.6447","url":null,"abstract":"<p><p><b>Objective:</b> Male infertility is involved in about half of the casess of infertility and the only sole reason for infertility in 20%-30% of the cases. Following the recent interest in the use of medicinal plants, scientists have sought to clarify their effects on male fertility. This review aimed to summarize the results of studies available to determine the effectiveness, safety and mechanism of herbal treatments in the improvement of male fertility. <b>Materials and methods:</b> Medline/PubMed, Scopus, Science Direct, and the Cochrane Central Register of Controlled Trials (Central) databases were searched for randomized controlled trials (RCTs) published during 2000-2020. Studies were only included if they adhered to the CONSORT checklist. The methodological quality of the selected studies was assessed using the Cochrane risk of bias tool. <b>Results:</b> Finally, 20 studies recruiting a total of 1519 individuals were reviewed. These studies compared the effects of eleven different medicinal plants, i.e. ginseng, saffron, <i>Nigella sativa</i>, palm pollen, ADOFON, TOPALAF, sesame, and <i>Mucuna pruriens</i>, on male fertility with those of placebo. All studies (except one) confirmed the beneficial effects of medicinal plants on the improvement of sperm and reproductive parameters and thus male infertility. <b>Conclusion:</b> The existing RCTs indicated the positive effects of medicinal plants on male fertility. Therefore, in order to develop a novel approach to the treatment of male infertility, further clinical trials are warranted to determine the maximum dosage and duration of treatment with herbal medicines and evaluate any potential side effects of such interventions.</p>","PeriodicalId":15845,"journal":{"name":"Journal of Family and Reproductive Health","volume":"15 2","pages":"74-81"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4e/77/JFRH-15-74.PMC8520662.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39579763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Comparison of the Effect of Nifedipine Alone and the Combination of Nifedipine and Sildenafil in Delaying Preterm Labor: A Randomized Clinical Trial. 硝苯地平单用与硝苯地平联合西地那非延缓早产的随机临床试验比较。
Journal of Family and Reproductive Health Pub Date : 2021-06-01 DOI: 10.18502/jfrh.v15i2.6452
Elham Mohammadi, Somayyeh Noei Teymoordash, Ali Reza Norouzi, Fatemeh Norouzi, Hamid Reza Norouzi
{"title":"Comparison of the Effect of Nifedipine Alone and the Combination of Nifedipine and Sildenafil in Delaying Preterm Labor: A Randomized Clinical Trial.","authors":"Elham Mohammadi,&nbsp;Somayyeh Noei Teymoordash,&nbsp;Ali Reza Norouzi,&nbsp;Fatemeh Norouzi,&nbsp;Hamid Reza Norouzi","doi":"10.18502/jfrh.v15i2.6452","DOIUrl":"https://doi.org/10.18502/jfrh.v15i2.6452","url":null,"abstract":"<p><p><b>Objective:</b> Recently, sildenafil as a drug effective in relaxing smooth muscles can be used as an adjunct to delay the onset of uterine contractions and therefore the occurrence of preterm labor. The aim of this study was to evaluate the effect of nifedipine combination with sildenafil on preterm delivery compared with nifedipine alone. <b>Materials and methods:</b> This randomized double-blinded clinical trial was performed on pregnant women with a gestational age of 26-34 weeks with singleton pregnancy and symptoms of preterm delivery. The mothers were randomly assigned into two groups receiving nifedipine plus sildenafil or those receiving nifedipine alone. The time of delivery, maternal and neonatal complications were compared between the two groups. <b>Results:</b> Mothers who received the combination therapy experienced significantly lower preterm delivery within 72 hours of intervention compared to nifedipine alone (4.5% versus 27.3%, p = 0.002). The rate of delivery during the first 7 days after discharge was 7.6% and 31.8% in nifedipine plus sildenafil and nifedipine alone, respectively (P = 0.001). The prevalence of neonatal respiratory distress syndrome (RDS) as well as mean birth weight was higher in the nifedipine group alone. Treatment protocol with nifedipine and sildenafil compared with nifedipine alone was associated with a significant increase in preterm delivery delay (beta =-5.819, p = 0.001). <b>Conclusion:</b> The use of sildenafil in addition to nifedipine causes more delay in delivery in cases of preterm labor, followed by lower risk for RDS, reduces neonatal intensive care unit (NICU) admission, and preserves neonatal birth weight.</p>","PeriodicalId":15845,"journal":{"name":"Journal of Family and Reproductive Health","volume":"15 2","pages":"112-117"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2a/f7/JFRH-15-112.PMC8520666.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39579768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
The Effect of Twisted Uterus Caused by Endometriosis or Myomatosis on Reproductive Treatment Outcomes. 子宫内膜异位症或肌瘤所致扭曲子宫对生殖治疗效果的影响。
Journal of Family and Reproductive Health Pub Date : 2021-06-01 DOI: 10.18502/jfrh.v15i2.6451
Belen Moliner, Francisco Sellers, Andrea Bernabeu, Ana Fuentes, Juan Carlos Castillo, Joaquin Llacer, Rafael Bernabeu
{"title":"The Effect of Twisted Uterus Caused by Endometriosis or Myomatosis on Reproductive Treatment Outcomes.","authors":"Belen Moliner,&nbsp;Francisco Sellers,&nbsp;Andrea Bernabeu,&nbsp;Ana Fuentes,&nbsp;Juan Carlos Castillo,&nbsp;Joaquin Llacer,&nbsp;Rafael Bernabeu","doi":"10.18502/jfrh.v15i2.6451","DOIUrl":"https://doi.org/10.18502/jfrh.v15i2.6451","url":null,"abstract":"<p><p><b>Objective:</b> Twisted uterus is detected when the body of the uterus is rotated from the cervical canal. This anomaly may be due to different causes, such as uterine fibroids, endometriosis or the presence of both. The study has aimed to compare the effect of the twisted uterus cause in terms of reproductive treatment outcomes. <b>Materials and methods:</b> It consisted of a retrospective study of twisted uterus cases with repeated implantation failure (more than three embryo transfers or four blastocysts transferred unsuccessfully) in our ultrasound department. The twisted uterus was defined when the vaginal probe needed to be rotated to assess the endometrial line thoroughly or when the coronal view was seen by 2D scan. From 2017 to 2020, 879 gynecological ultrasounds were performed. For statistical analysis, we carried out a logistical regression analysis adjusted by confounding factors. <b>Results:</b> From 145 patients included only 92 patients underwent reproductive treatments. With the known cause of uterine torsion. 56 patients with endometriosis, 18 with uterine myoma and the remaining 18 suffered from both. After assisted reproductive treatment, the endometriosis group showed the highest clinical pregnancy rate (53.57%) compared to myoma (22.22%) and endometriosis and myoma (38.89%) groups. <b>Conclusion:</b> Uterine myoma capable of causing uterine torsion may affect embryo implantation more than endometriosis. Prospective randomized studies with a larger number of patients would be needed to confirm these findings.</p>","PeriodicalId":15845,"journal":{"name":"Journal of Family and Reproductive Health","volume":"15 2","pages":"106-111"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ee/7c/JFRH-15-106.PMC8520668.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39579767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Lysophosphatidic Acid on the Vascular Endothelial Growth Factor Expression in Autotransplanted Mouse Ovaries Encapsulated in Sodium Alginate. 溶血磷脂酸对海藻酸钠包埋小鼠卵巢自体移植血管内皮生长因子表达的影响。
Journal of Family and Reproductive Health Pub Date : 2021-06-01 DOI: 10.18502/jfrh.v15i2.6449
Maryam Dehghan, Shirin Shahbazi, Mojdeh Salehnia
{"title":"Effect of Lysophosphatidic Acid on the Vascular Endothelial Growth Factor Expression in Autotransplanted Mouse Ovaries Encapsulated in Sodium Alginate.","authors":"Maryam Dehghan,&nbsp;Shirin Shahbazi,&nbsp;Mojdeh Salehnia","doi":"10.18502/jfrh.v15i2.6449","DOIUrl":"https://doi.org/10.18502/jfrh.v15i2.6449","url":null,"abstract":"<p><p><b>Objective:</b> The aim of this study was to evaluate the effect of lysophosphatidic acid (LPA) supplementation during in vitro culture and transplantation of mouse ovaries on the follicular development and expression of vascular endothelial growth factor (VEGF) as an angiogenesis factor at the mRNA and protein levels. <b>Materials and methods:</b> Three weeks old mice ovaries were cultured in the presence and absence of LPA for 24 hours, then they were capsulated in sodium alginate in the presence and absence of LPA as four experimental groups. After transplantation the vaginal smears were performed daily to evaluate the initiation of the estrous cycle. The morphology and follicular distribution were analyzed at the first and fourth estrous cycles using hematoxylin and eosin staining. Then in the groups that showed higher and lower follicular development the immunohistochemistry assay was conducted to identify VEGF protein expression, and the real time RT-PCR was done to analyze the expression of <i>Vegf</i> gene at the first estrus cycle. <b>Results:</b> The large size follicles and also the corpus luteum were prominent in all transplanted groups at fourth estrus cycle in comparison with intact control groups. The statistically lowest percentage of small size follicles and the highest percentages of large size follicles were seen in LPA<sup>+</sup>/LPA<sup>-</sup> group (p<0.05). The expression ratio of <i>Vegf</i> to <i>β-actin</i> was significantly higher in this group in comparison with non-LPA treated and intact control groups (p <0.05). <b>Conclusion:</b> LPA as an angiogenesis factor increases the follicular development in transplanted ovaries but it causes early discharge of ovarian reserve.</p>","PeriodicalId":15845,"journal":{"name":"Journal of Family and Reproductive Health","volume":"15 2","pages":"91-98"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0a/61/JFRH-15-91.PMC8520664.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39579765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fragile X Syndrome Secondary to in Vitro Fertilization With a Family Egg Donor: A Case Report and Review of the Literature. 家庭卵子供体体外受精继发脆性X综合征1例报告及文献复习。
Journal of Family and Reproductive Health Pub Date : 2021-06-01 DOI: 10.18502/jfrh.v15i2.6455
Laura Yuriko González-Teshima, César Payán-Gómez, Wilmar Saldarriaga
{"title":"Fragile X Syndrome Secondary to in Vitro Fertilization With a Family Egg Donor: A Case Report and Review of the Literature.","authors":"Laura Yuriko González-Teshima,&nbsp;César Payán-Gómez,&nbsp;Wilmar Saldarriaga","doi":"10.18502/jfrh.v15i2.6455","DOIUrl":"https://doi.org/10.18502/jfrh.v15i2.6455","url":null,"abstract":"<p><p><b>Objective:</b> To evidence the need for screening fragile X syndrome (FXS) in egg donors in assisted reproduction protocols. <b>Case report</b> <b>:</b> This is the report of a boy with FXS who inherited the mutated allele from an ovule donated by the mother´s sister through an assisted reproduction protocol. Identifying premutation (PM) carriers of FXS amongst gamete donors isn't part of the obligatory genetic analysis for donors and is only considered by most of the in vitro fertility societies and guidelines as part of the extension screening tests. <b>Conclusion:</b> It is cost-effective to do pre-conceptional screening for the PM or full mutation (FM) of the <i>FMR1</i> gene affected in FXS in every woman undergoing assisted reproductive methods, including gamete donors even without a positive family history of intellectual disabilities. This case supports the need of rethinking the guidelines on the necessary gamete donor screening tests in assisted reproduction protocols.</p>","PeriodicalId":15845,"journal":{"name":"Journal of Family and Reproductive Health","volume":"15 2","pages":"130-135"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/47/72/JFRH-15-130.PMC8520665.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39832633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Multiple Logistic Regression Model for Determinants of Injectable Contraceptive Uptake Among Women of Reproductive Age in Kenya. 肯尼亚育龄妇女注射避孕药摄取决定因素的多元Logistic回归模型。
Journal of Family and Reproductive Health Pub Date : 2021-06-01 DOI: 10.18502/jfrh.v15i2.6448
Ernest Kiplangat Kirui, Joseph Kyalo Mung'atu, Peter Gichangi, Nicholas Odhiambo Onguto, Davis Kiruki Kamondo
{"title":"Multiple Logistic Regression Model for Determinants of Injectable Contraceptive Uptake Among Women of Reproductive Age in Kenya.","authors":"Ernest Kiplangat Kirui,&nbsp;Joseph Kyalo Mung'atu,&nbsp;Peter Gichangi,&nbsp;Nicholas Odhiambo Onguto,&nbsp;Davis Kiruki Kamondo","doi":"10.18502/jfrh.v15i2.6448","DOIUrl":"https://doi.org/10.18502/jfrh.v15i2.6448","url":null,"abstract":"<p><p><b>Objective:</b> The recent increase in the uptake of injectable contraceptives has occurred at the expense of the other modern contraceptive methods but the knowledge gap still exists on modeling dynamics and determinants associated with the use of the injectable. This study sought to model for injectable contraceptive usage to bridge the knowledge gap on the use of injectable contraceptives among women of childbearing age in Kenya. <b>Materials and methods:</b> Analytical cross-sectional study design was adopted. Secondary data for women collected during the (Performance Monitoring for Action) PMA2020 survey was used. PMA2020 survey used multistage stratified sampling with urban-rural representation. To establish the factors associated with the uptake of injectable contraceptives, a multiple logistic regression model was fitted using Stata version 13 and R version 3.5.3 statistical software. Hosmer-Lemeshow Test statistic was used to evaluate the goodness of model fit in predicting injectable contraceptive usage. <b>Results:</b> Multivariable analysis showed that women with post-primary/vocational levels of education were 54% less likely to use an injectable contraceptive compared to those who had no education at all. Hosmer-Lemeshow (HL) goodness of fit test statistic indicated that the model was a good fit for prediction. Education, marital status, wealth quintile, place of residence and number of births were significant predictors of the injectable contraceptive uptake among women of reproductive age in Kenya. <b>Conclusion:</b> The findings of this study will inform the design of targeted interventions aimed at addressing the increasing demand for injectable devices among women of reproductive age in Kenya.</p>","PeriodicalId":15845,"journal":{"name":"Journal of Family and Reproductive Health","volume":"15 2","pages":"82-90"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/80/73/JFRH-15-82.PMC8520661.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39579764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Maternal Urinary Tract Infection: Is It Associated With Neonatal Urinary Tract Infection? 产妇尿路感染:是否与新生儿尿路感染有关?
Journal of Family and Reproductive Health Pub Date : 2021-03-01 DOI: 10.18502/jfrh.v15i1.6067
Huseyin Bilgin, Emine Esin Yalinbas, Ilknur Elifoglu, Sahinde Atlanoglu
{"title":"Maternal Urinary Tract Infection: Is It Associated With Neonatal Urinary Tract Infection?","authors":"Huseyin Bilgin,&nbsp;Emine Esin Yalinbas,&nbsp;Ilknur Elifoglu,&nbsp;Sahinde Atlanoglu","doi":"10.18502/jfrh.v15i1.6067","DOIUrl":"https://doi.org/10.18502/jfrh.v15i1.6067","url":null,"abstract":"<p><p><b>Objective:</b> Maternal urinary tract infection is associated with intrauterine growth restriction, preterm delivery and low birth weight. The purpose of this study was to evaluate whether maternal urinary tract infection is related to neonatal urinary tract infection. <b>Materials and methods:</b> The present prospective study included 230 singleton neonates. The participants were divided into two groups based on in utero exposure to maternal urinary tract infections. The study group (exposure to maternal urinary tract infection) included 115 neonates and the control group (without exposure to maternal urinary tract infection) included 115 healthy neonates. Physical examination, urinalysis, urine culture and urinary system ultrasonography were carried out for all neonates. <b>Results:</b> There were 153 deliveries by cesarean section and 77 vaginal births. There was no statistically significant difference between the groups in terms of gender distribution, maternal age, birth weight, mode of delivery, gravida and gestational age. Although the difference was not significant, the incidence of low birth weight and preterm delivery were higher in the study group in comparison to that in the control group. There was a statistically significant higher rate of neonatal urinary tract infection in the study group compared with control group (25.2% vs. 7.8%, p<0.001). The most commonly discovered pathogens were Escherichia coli, followed by Klebsiella spp., Proteus spp., and Serratia spp. in the study group. <b>Conclusion:</b> The results of this study showed that the presence of maternal urinary tract infection may contribute to increased urinary tract infection frequency in the neonatal period. Neonates at risk for a urinary tract infection should be regularly monitored due to nonspecific clinical presentation.</p>","PeriodicalId":15845,"journal":{"name":"Journal of Family and Reproductive Health","volume":"15 1","pages":"8-12"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bf/7b/JFRH-15-8.PMC8346740.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39340623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
An Unusual Case of Genital Lesion: A Vulvar Syringoma. 一个不寻常的生殖器病变病例:外阴注射器瘤。
Journal of Family and Reproductive Health Pub Date : 2021-03-01 DOI: 10.18502/jfrh.v15i1.6080
Paola Algeri, Rosita Rodella, Cinzia Manfredini, Maurizio Algeri
{"title":"An Unusual Case of Genital Lesion: A Vulvar Syringoma.","authors":"Paola Algeri,&nbsp;Rosita Rodella,&nbsp;Cinzia Manfredini,&nbsp;Maurizio Algeri","doi":"10.18502/jfrh.v15i1.6080","DOIUrl":"https://doi.org/10.18502/jfrh.v15i1.6080","url":null,"abstract":"<p><p><b>Objective:</b> Syringoma is a benign adnexal neoplasm of sweat gland, usually presenting as extra-genital lesions, while vulvar localization is rare. Moreover, syringoma is an uncommon vulvar neoplasms. <b>Case report</b> <b>:</b> A 44-year-old woman with previous diagnosis of duodenal gastrointestinal stromal tumour, underwent a local surgical excision for an isolated, painful, vulvar lesion. The specimen was submitted for histological examination. A vulvar syringoma was diagnosed. <b>Conclusion:</b> We describe this case according on its rarity and atypical presentation as well; therefore, vulvar neoplasms encompass many differential diagnoses, among which the incidence rate of syringoma is very low. Although its rarity, syringoma should be included among the differential diagnosis for vulvar neoplasm.</p>","PeriodicalId":15845,"journal":{"name":"Journal of Family and Reproductive Health","volume":"15 1","pages":"70-73"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f2/42/JFRH-15-70.PMC8346743.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39341054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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