Alzheimer's Disease [Working Title]最新文献

筛选

英文中文

An Innovative Framework for Integrative Rehabilitation in Dementia 痴呆综合康复的创新框架

Alzheimer's Disease [Working Title] Pub Date : 2022-01-21 DOI: 10.5772/intechopen.101863

V. Bragin, Ilya Bragin

{"title":"An Innovative Framework for Integrative Rehabilitation in Dementia","authors":"V. Bragin, Ilya Bragin","doi":"10.5772/intechopen.101863","DOIUrl":"https://doi.org/10.5772/intechopen.101863","url":null,"abstract":"Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with multiple pathophysiological mechanisms affecting every organ and system in the body. Cerebral hypoperfusion, hypoxia, mitochondrial failure, abnormal protein deposition, multiple neurotransmitters and synaptic failures, white matter lesions, and inflammation, along with sensory-motor system dysfunctions, hypodynamia, sarcopenia, muscle spasticity, muscle hypoxia, digestive problems, weight loss, and immune system alterations. Rehabilitation of AD patients is an emerging concept aimed at achieving optimum levels of physical and psychological functioning in the presence of aging, neurodegenerative processes, and progression of chronic medical illnesses. We hypothesize that the simultaneous implementation of multiple rehabilitation modalities can delay the progression of mild into moderate dementia. This chapter highlights recent research related to a novel treatment model aimed at modifying the natural course of AD and delaying cognitive decline for medically ill community-dwelling patients with dementia. For practical implementation of rehabilitation in AD, the standardized treatment protocols are warranted.","PeriodicalId":158101,"journal":{"name":"Alzheimer's Disease [Working Title]","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132873472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alzheimer: A Complex Genetic Background 阿尔茨海默病:复杂的遗传背景

Alzheimer's Disease [Working Title] Pub Date : 2021-12-28 DOI: 10.5772/intechopen.101455

M. Calabrò, C. Crisafulli

引用次数: 0