Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)最新文献
Chih-lung Lin, W. Kang, C. Hu, S. Young, J. Lai, Maw-huei Lee, T. Kuo
{"title":"Improved EMG pattern recognition using the distribution plot of cepstrum","authors":"Chih-lung Lin, W. Kang, C. Hu, S. Young, J. Lai, Maw-huei Lee, T. Kuo","doi":"10.1109/IEMBS.1998.744996","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.744996","url":null,"abstract":"In this paper, a real-time on-line plot is developed which recognizes user motion using the first and second cepstral coefficients for pattern recognition of the electromyogram (EMG). The cepstral coefficients, derived from autoregressive coefficients and estimated by a recursive least square algorithm, are used as the recognition features. The features are then discriminated using a modified maximum likelihood distance classifier. The cross distribution of the first and second cepstral coefficients can be plotted real-time and on-line. The physician or user can adjust the specific motions to attain optimal recognition results using this information. Subjects can be trained to contract muscles in specified and easily achievable patterns by the distribution plot. The recognition results can be used as myoelectric prosthetic control, or providing commands for the human-computer interface.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"148 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134402743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Detection sensitivity enhancements for fluorescence imaging with multi-photon excitation microscopy","authors":"D. Wokosin, W. Amos, J. G. White","doi":"10.1109/IEMBS.1998.746913","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.746913","url":null,"abstract":"Multiphoton excitation microscopy (MPEM) offers several distinct advantages over laser scanning confocal microscopy (LSCM). One is that the resolution and the thickness of the optical section are determined by the excitation beam; a confocal detection aperture is therefore unnecessary. This feature allows the photodetector to be relocated from its usual location in the descanned emission beam within a confocal scan head so as to directly intercept the emitted fluorescent signal emerging from the microscope. The enhancement in signal gained by changing from internal to whole area (external) detection in this way has been evaluated quantitatively. In particular, longitudinal chromatic aberration has been shown to reduce the efficiency of internal detection relative to external. Also, a novel optical design is described, which allows increased collection efficiency with MPEM by capturing light emitted away from the objective lens. Together, these two enhancements typically provide an improvement in efficiency of at least 4.5 times, and even greater inside thick and scattering specimens. Such improvements are crucial for extending the longevity of living preparations by minimizing phototoxic exposure during observation. They also enable deeper imaging inside specimens where signal loss by scattering has previously limited the obtainable sectioning depth.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"299 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127563532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Magnetoencephalography and functional MRI: a quantitative study of speech perception","authors":"T. Roberts, D. Poeppel, H. Rowley","doi":"10.1109/IEMBS.1998.747027","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.747027","url":null,"abstract":"Magnetoencephalography (MEG), sensitive to evoked neuronal activity, and functional magnetic resonance imaging (fMRI), sensitive to hemodynamic consequences of cortical activation, were compared in normal subjects, presented with simple speech elements (vowels). The subjects were instructed either to listen passively or to perform phonetic or pitch discrimination tasks. Sources of activation detected using the two technologies were found to co-localize in the superior temporal gyrus. Furthermore quantification of the evoked responses, using both techniques, revealed a task-induced bilateral increase in activation, with the greatest increases observed in the left hemisphere, during performance of the phonetic discrimination task. It is concluded that not only do fMRI and MEG indicate similar underlying cortical activation areas, but that they offer quantitative indices of hemispheric lateralization induced by performance of a linguistic task. Their co-variance with respect to hemisphere and task performance suggests that despite their different neurophysiological sensitivities (hemodynamic changes vs. neuronal electrical activity), both techniques offer quantitative approaches to the study of speech perception, and by extension, to the processing of language.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133627956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Calhoun, T. Adalı, M. Kraut, P. Rivkin, G. Pearlson
{"title":"Visualizing spatially distributed hemodynamic lag times in event-related functional MRI: estimation of a characteristic visual \"impulse response\"","authors":"V. Calhoun, T. Adalı, M. Kraut, P. Rivkin, G. Pearlson","doi":"10.1109/IEMBS.1998.747028","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.747028","url":null,"abstract":"Functional MRI is a technique capable of providing spatial and temporal information about the brain's hemodynamics. It has been observed that the onset of observed signal changes can vary across regions exhibiting activation. The authors have developed a method for extracting information about these timing differences and for observing the temporal-spatial distribution of the blood response by, characterizing a typical hemodynamic response (HR) to a single flash of light repeated at 30 s intervals. They anatomically locate voxels in the primary visual cortex, a region located along the calcarine sulcus, which is the main terminus of the geniculocortical visual pathways. This average response profile is correlated with the data, producing a map of \"active\" voxels. Next, the authors explore the distribution of lags by shifting the HR, correlating this signal with the data, and producing another map. They observed increased activation in non-primary visual cortex as the lag was increased to 2-3 s. These results can be most effectively displayed in a time lapse movie. The described technique provides a way of determining varying hemodynamic lag times and partitioning \"activated\" regions in time. It also clearly demonstrates that these time lags do differ spatially.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129989446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cortical source modeling and imaging","authors":"Bin He","doi":"10.1109/IEMBS.1998.746907","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.746907","url":null,"abstract":"It is of importance to non-invasively image dynamic brain electrical activity from scalp electric measurements. Models of cortical equivalent sources have been developed in the past decade to account for the distributed brain electrical activity. Such cortical equivalent source models provide a means to circumvent the non-uniqueness of the brain inverse problem and to enable non-invasive imaging of brain electric activity over the epicortical surface. This paper reviews the authors' recent work on cortical source modeling and cortical imaging from scalp EEG measurements.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132560870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Ishihara, T. Arai, M. Kikuchi, H. Nakano, M. Obara
{"title":"Temperature measurements by thermal radiation during ArF excimer laser ablation with gelatin gel","authors":"M. Ishihara, T. Arai, M. Kikuchi, H. Nakano, M. Obara","doi":"10.1109/IEMBS.1998.746960","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.746960","url":null,"abstract":"We measured temperature elevation during photorefractive keratectomy (PRK) by thermal radiation. The thermal radiation from ablating surface of gelatin gel (15%wt) by ArF excimer laser was detected by a MCT detector with 1 /spl mu/s rise time. The measured signal increased sharply just after the laser pulse and decreased quasi-exponentially. We calculated the temperature elevation using Stefan-Boltzmann radiation law. The maximum temperature elevation was 97/spl deg/C at 208 mJ/cm/sup 2/ in laser fluence. The temperature elevation over 60/spl deg/C was kept for 85 /spl mu/s. These temperature elevation might induce possible heat damage on ablated surface. Our high temporal resolution temperature monitoring may be available to achieve safety and precise PRK.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126828847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Automatic body temperature control system for small animal studies using dual mode PI control","authors":"Hyung Il Kim, Hee Chan Kim, Byoung Woo Yoon","doi":"10.1109/IEMBS.1998.746987","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.746987","url":null,"abstract":"Body temperature regulation of an experimental animal is important because anesthesia reduces the body temperature and deteriorates the physiological condition of the animal. We have developed an automatic body temperature control system based on a microcontroller (80C196KC) with a dual mode proportional integral (PI) control algorithm where two different sets of PI gain coefficients were used depending on the response state. The developed system also provides user interface through an LCD display and two push button inputs and PC interface through RS-232 serial communication protocol. Through in-vitro and in-vivo tests, we were able to maintain the temperature of the target object within the range /spl plusmn/0.3/spl deg/C of the set point temperature.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130767222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"3-D spatial sensitivity profiles of head model in near-infrared spectroscopy","authors":"E. Okada","doi":"10.1109/IEMBS.1998.746958","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.746958","url":null,"abstract":"The heterogeneity of tissue scattering makes determination of sampling volume of near infrared spectroscopy (NIRS) instruments difficult. The 3-D spatial sensitivity profiles, which indicate the volume of tissue sampled by an NIRS instrument, in the head models are predicted by the Monte Carlo method. The spatial sensitivity profile is strongly affected by the clear cerebrospinal fluid (CSF) surrounding the brain. In the model with the CSF, the spatial sensitivity profile spreads over an extensive area in the brain surface between the source and detector but it is confined to a shallow region in the brain.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125955762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A guided acoustic wave method for characterization of medical ultrasound transducers","authors":"Rui Zhang, M. Wan, W. Cao","doi":"10.1109/IEMBS.1998.746943","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.746943","url":null,"abstract":"A guided acoustic wave technique for nondestructive evaluation (NDE) of the medical ultrasound transducers is presented. A revised reflection coefficient measurement technique is used to obtain the dispersion curves of the Lamb waves by finding the local minimum of the broad band reflection spectrum. A set of specimens with controlled interface conditions between the matching layer and the piezoelectric layer are tested. The results of experiment show there is strong relation between the position of the turning point in the lowest order mode dispersion curve and bond quality of transducers.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131786407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Hutten, H. Scharfetter, W. Ninaus, Bernhard Puswald, G. I. Petrova, D. Kovachev
{"title":"Inductively coupled wideband transceiver for bioimpedance spectroscopy (IBIS)","authors":"H. Hutten, H. Scharfetter, W. Ninaus, Bernhard Puswald, G. I. Petrova, D. Kovachev","doi":"10.1109/IEMBS.1998.746936","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.746936","url":null,"abstract":"Most measurement devices for bioimpedance spectroscopy are coupled to the measured object (tissue) via electrodes. At frequencies >500 kHz they suffer from artifacts due to stray capacitances between electrode leads as well as between ground and object. The non-invasive measurement of the brain conductivity is hardly possible with surface electrodes. These disadvantages can be obviated by inductive coupling. The aim of this work was the development of a wideband transceiver. In order to define its specifications a feasibility study has been carried out with a simulation model for two different coil systems above a homogeneous conducting plate. According to simulation results both systems render possible to resolve conductivity changes down to 10/sup -3/(/spl Omega/m)/sup -1/ at 50 kHz. The sensitivity increases with the square of the frequency. The receiver electronics must then resolve voltages >=1 /spl mu/V at an excitation current of 1 A. We have realized a transceiver which matches these specifications with a S/N-ratio of 22 dB at 1 /spl mu/V. The frequency range is 50 kHz-5 MHz.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124401199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}