{"title":"Comparative evaluation of intranasal midazolam-ketamine, dexmedetomidine-ketamine, midazolam-fentanyl, and dexmedetomidine-fentanyl combinations for procedural sedation and analgesia in pediatric dental patients: a randomized controlled trial.","authors":"Abhilasha Agarwal, Afroz Alam Ansari, Rajendra Nath, Rakesh Kumar Chak, Rajeev Kumar Singh, Richa Khanna, Prem Raj Singh","doi":"10.17245/jdapm.2023.23.2.69","DOIUrl":"https://doi.org/10.17245/jdapm.2023.23.2.69","url":null,"abstract":"<p><strong>Background: </strong>In order to assess the effectiveness of various analgesio-sedative combinations for pain relief and sedation in pediatric dental patients, a thorough evaluation of clinical studies and patient outcomes is necessary.</p><p><strong>Methods: </strong>A total of 128 healthy, uncooperative pediatric dental patients were randomly allocated to receive one of the four combinations of drugs via the intranasal (IN) route: Group I received midazolam-ketamine (MK), Group II received dexmedetomidine-ketamine (DK), Group III received midazolam-fentanyl (MF), and Group IV received dexmedetomidine-fentanyl (DF) in a parallel-arm study design. The efficacy and safety of the combinations were evaluated using different parameters.</p><p><strong>Results: </strong>The onset of sedation was significantly faster in the DF group than in the DK, MF, and MK groups (P < 0.001). The depth of sedation was significantly higher in the DK and DF groups than in the MK and MF groups (P < 0.01). DK and DF produced significant intra- and postoperative analgesia when compared with combinations of MK and MF. No significant adverse events were observed for any of the combinations.</p><p><strong>Conclusions: </strong>The DK and DF groups showed potential as analgesio-sedatives in view of their anxiolytic and analgesic effects.</p>","PeriodicalId":15634,"journal":{"name":"Journal of Dental Anesthesia and Pain Medicine","volume":"23 2","pages":"69-81"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/23/74/jdapm-23-69.PMC10079769.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9278969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum: Addendum: Comparative evaluation of efficacy of external vibrating device and counterstimulation on child's dental anxiety and pain perception during local anesthetic administration: a clinical trial.","authors":"Varada Sahithi, Kanamarlapudi Venkata Saikiran, Mahesh Nunna, Sainath Reddy Elicherla, Ramasubba Reddy Challa, Sivakumar Nuvvula","doi":"10.17245/jdapm.2023.23.2.121","DOIUrl":"https://doi.org/10.17245/jdapm.2023.23.2.121","url":null,"abstract":"<p><p>[This corrects the article on p. 345 in vol. 21, PMID: 34395902.].</p>","PeriodicalId":15634,"journal":{"name":"Journal of Dental Anesthesia and Pain Medicine","volume":"23 2","pages":"121"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/25/de/jdapm-23-121.PMC10079772.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9273605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful repair of a partially transected endotracheal tube with Dermabond surgical adhesive during a Lefort osteotomy: a case report.","authors":"Daniel Ahn, Tuan-Hsing Loh","doi":"10.17245/jdapm.2023.23.2.117","DOIUrl":"https://doi.org/10.17245/jdapm.2023.23.2.117","url":null,"abstract":"<p><p>Damage to the endotracheal tube (ETT) during oral and maxillofacial surgeries is a rare but serious intraoperative complication. Herein, we present a case of a partially damaged ETT that was repaired using Dermabond surgical adhesive (Ethicon, Sommerville, NJ, USA) during a Lefort osteotomy. Dermabond surgical adhesive can be a simple and viable tool to repair partially transected ETTs where ETT exchange carries a high risk of airway loss. Our case adds to one of the several techniques for managing damaged ETT in an intraoperative setting.</p>","PeriodicalId":15634,"journal":{"name":"Journal of Dental Anesthesia and Pain Medicine","volume":"23 2","pages":"117-119"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ae/15/jdapm-23-117.PMC10079768.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9278967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"General anesthesia with a transcutaneous pacemaker for a Noonan syndrome patient with advanced atrioventricular block discovered in the remote period after open-heart surgery: a case report.","authors":"Emi Ishikawa, Makiko Shibuya, Ayako Yokoyama, Takayuki Hojo, Yukifumi Kimura, Toshiaki Fujisawa","doi":"10.17245/jdapm.2023.23.2.111","DOIUrl":"https://doi.org/10.17245/jdapm.2023.23.2.111","url":null,"abstract":"We provided general anesthesia management to a patient with advanced atrioventricular block, which was discovered in the remote period after open-heart surgery. A 21-year-old man with Noonan syndrome was scheduled to undergo excision of a median intramandibular tumor. At 2 months of age, the patient underwent endocardial repair for congenital heart disease. During our preoperative examination, an atrioventricular block was detected, which had not been previously noted. Emergency drugs were administered, and a transcutaneous pacemaker was placed. During anesthesia induction, mask ventilation was easy, and intubation was performed smoothly using a video laryngoscope. The transcutaneous pacemaker was activated in demand mode at a pacing rate of 50 cycles/min approximately throughout the anesthesia time, and the hemodynamic status remained stable. The effect of intraoperatively administered atropine was brief, lasting only a few seconds. Although body movements due to thoracoabdominal muscle spasm were observed during pacemaker activation, they did not interfere with surgery. In postoperative patients with congenital heart disease, an atrioventricular block may be identified in the remote period, and preoperative evaluation should be based on this possibility. In addition, during anesthesia management, it is important to prepare multiple measures to maintain hemodynamic status.","PeriodicalId":15634,"journal":{"name":"Journal of Dental Anesthesia and Pain Medicine","volume":"23 2","pages":"111-116"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/20/30/jdapm-23-111.PMC10079770.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9278962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of the annual changes in dental institutions that claimed dental sedatives in Korea and the types of sedatives using health care big data.","authors":"Minjae Lee, Seong In Chi, Hyuk Kim, Kwang-Suk Seo","doi":"10.17245/jdapm.2023.23.2.101","DOIUrl":"https://doi.org/10.17245/jdapm.2023.23.2.101","url":null,"abstract":"<p><strong>Background: </strong>Dentists make various efforts to reduce patients' anxiety and fear associated with dental treatment. Dental sedation is an advanced method that dentists can perform to reduce patients' anxiety and fear and provide effective dental treatment. However, dental sedation is different from general dental treatment and requires separate learning, and if done incorrectly, can lead to serious complications. Therefore, sedation is performed by a limited number of dentists who have received specific training. This study aimed to investigate the proportion of dentists who practice sedation and the main sedatives they use in the context of the Republic of Korea.</p><p><strong>Methods: </strong>We used the customized health information data provided by the Korean National Health Insurance. We investigated the number of dental hospitals or clinics that claimed insurance for eight main sedatives commonly used in dental sedation from January, 2007 to September, 2019 at the Health Insurance Review and Assessment Service. We also identified the changes in the number of dental medical institutions by region and year and analyzed the number and proportion of dental medical institutions prescribing each sedative.</p><p><strong>Results: </strong>In 2007, 302 dental hospitals prescribed sedatives, and the number increased to 613 in 2019. In 2007, approximately 2.18% of the total 13,796 dental institutions prescribed sedatives, increasing to 3.31% in 2019. In 2007, 168 institutions (55.6%) prescribed N<sub>2</sub>O alone, and in 2019, 510 institutions (83.1%) made claims for it. In 2007, 76 (25.1%) hospitals made claims for chloral hydrate, but the number gradually decreased, with only 29 hospitals (4.7%) prescribing it in 2019. Hospitals that prescribed a combination of N<sub>2</sub>O, chloral hydrate, and hydroxyzine increased from 27 (8.9%) in 2007 to 51 (9%) in 2017 but decreased to 38 (6.1%) in 2019. The use of a combination of N<sub>2</sub>O and midazolam increased from 20 hospitals (6.6%) in 2007 to 51 hospitals (8.3%) in 2019.</p><p><strong>Conclusion: </strong>While there is a critical limitation to the investigation of dental hospitals performing sedation using insurance claims data, namely exclusion of dental clinics providing non-insured treatments, we found that in 2019, approximately 3.31% of the dental clinics were practicing sedation and that N<sub>2</sub>O was the most commonly prescribed sedative.</p>","PeriodicalId":15634,"journal":{"name":"Journal of Dental Anesthesia and Pain Medicine","volume":"23 2","pages":"101-110"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e7/fe/jdapm-23-101.PMC10079767.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9273461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Incidence of postoperative pain after using single continuous, single reciprocating, and full sequence continuous rotary file system: a prospective randomized clinical trial.","authors":"Umesh Kumar, Pragnesh Parmar, Ruchi Vashisht, Namita Tandon, Charan Kamal Kaur","doi":"10.17245/jdapm.2023.23.2.91","DOIUrl":"https://doi.org/10.17245/jdapm.2023.23.2.91","url":null,"abstract":"<p><strong>Background: </strong>Extrusion of debris is a major factor that results in postoperative pain during root canal treatment with various instruments and instrumentation techniques. Therefore, instrumentation techniques that extrude minimal debris into the periapical area while reducing pain are desirable. This study aimed to compare the incidence of postoperative pain and intake of analgesic medication (frequency and quantity) after endodontic treatment of mandibular posterior teeth using two single files and full-sequence continuous rotary systems with different kinematic motions.</p><p><strong>Methods: </strong>Thirty-five of 105 patients were assigned equally to three groups according to the instrumentation system used: ProTaper Next (PN) X2, 25/06 (Dentsply, Maillefer, Ballaigues, Switzerland), One Shape (OS), #0.25/06 (Micro Mega, Besancon, France), and Wave One Gold (WG), Red - #0.25, 0.07 (Dentsply, Maillefer, Ballaigues, Switzerland). Five specialists were included in this study design; each professional prepared 21 teeth, and randomly selected 7 per instrument system. The VAS sheet ranging from 0 to 10 was used to record the initial and postoperative pains at 24, 48, and 72 h, and 7<sup>th</sup> day after single visit endodontic treatment in mandibular premolars and molars with a diagnosis of asymptomatic irreversible pulpitis with or without apical periodontitis. Postoperatively, an analgesic, ibuprofen 400 mg was administered for intolerable pain at a dose of 1 tablet for 6 h. The patients were asked over the telephone regarding postoperative pain at intervals of 24, 48, and 72 h, and 7<sup>th</sup> day using a visual analogue scale.</p><p><strong>Result: </strong>There were no statistically significant differences among the PN, OS, and WG systems (P > 0.05) with regard to the incidence of postoperative pain at any of the four time points assessed.</p><p><strong>Conclusion: </strong>The intensity of postoperative pain, frequency, and analgesic intake were similar across all three types of instrument systems; however, the reciprocating single file (WG) was associated with less postoperative pain than the full sequence continuous rotary file.</p>","PeriodicalId":15634,"journal":{"name":"Journal of Dental Anesthesia and Pain Medicine","volume":"23 2","pages":"91-99"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a9/d4/jdapm-23-91.PMC10079766.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9278970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of general anesthesia on the postoperative sleep cycle in patients undergoing surgery and dental treatment: a scoping review on the incidence of postoperative sleep disturbance.","authors":"Terumi Ayuse, Shinji Kurata, Gaku Mishima, Mizuki Tachi, Erika Suzue, Kensuke Kiriishi, Yu Ozaki-Honda, Takao Ayuse","doi":"10.17245/jdapm.2023.23.2.59","DOIUrl":"10.17245/jdapm.2023.23.2.59","url":null,"abstract":"<p><p>General anesthesia may influence the postoperative sleep cycle; however, no clinical studies have fully evaluated whether anesthesia causes sleep disturbances during the postoperative period. In this scoping review, we explored the changes in postoperative sleep cycles during surgical procedures or dental treatment under general anesthesia. We compared and evaluated the influence of general anesthesia on sleep cycles and sleep disturbances during the postoperative period in adult and pediatric patients undergoing surgery and/or dental treatment. Literature was retrieved by searching eight public databases. Randomized clinical trials, observational studies, observational case-control studies, and cohort studies were included. Primary outcomes included the incidence of sleep, circadian cycle alterations, and/or sleep disturbances. The search strategy yielded six studies after duplicates were removed. Finally, six clinical trials with 1,044 patients were included. In conclusion, general anesthesia may cause sleep disturbances based on alterations in sleep or the circadian cycle in the postoperative period in patients scheduled for elective surgery.</p>","PeriodicalId":15634,"journal":{"name":"Journal of Dental Anesthesia and Pain Medicine","volume":"23 2","pages":"59-67"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/64/3a/jdapm-23-59.PMC10079771.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9273606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karpal Singh Sohal, Frank Bald, Samwel Mwalutambi, Paulo J Laizer, David K Deoglas, Jeremiah Robert Moshy, Baraka Kileo, Noah Joshua, Sospeter Sewangi
{"title":"Establishment of an intravenous conscious sedation service at a University Dental Clinic in Tanzania.","authors":"Karpal Singh Sohal, Frank Bald, Samwel Mwalutambi, Paulo J Laizer, David K Deoglas, Jeremiah Robert Moshy, Baraka Kileo, Noah Joshua, Sospeter Sewangi","doi":"10.17245/jdapm.2023.23.2.83","DOIUrl":"https://doi.org/10.17245/jdapm.2023.23.2.83","url":null,"abstract":"<p><strong>Background: </strong>With advances in safety measures for anesthesia, conscious sedation has gained popularity in the field of dentistry and has become essential in dental practice worldwide. However, in Tanzania, intravenous (IV) sedation is rarely practiced in the dental field. Therefore, we report the establishment of sustainable IV conscious sedation in dental practices and subsequently train local OMS residents in Tanzania.</p><p><strong>Methods: </strong>In 2019, intravenous conscious sedation was initiated at the University Dental Clinic of the Muhimbili University of Health and Allied Science (MUHAS), Tanzania. During the preparatory phase of the program, local oral and maxillofacial surgeons (OMSs) were given a series of lecture notes that concentrated on different aspects of IV conscious sedation in dentistry. During the on-site training phase, an oral surgeon from the United States joined the OMSs for case selection, IV-conscious sedation procedures, and patient follow-up. Patients were recruited from existing patient records at the MUHAS Dental Clinic.</p><p><strong>Results: </strong>The first conscious IV sedation program in dentistry was successfully launched at the University Dental Clinic in Tanzania. The local team of OMSs was trained on the safe administration of sedative agents (midazolam or ketamine) to perform various minor surgical procedures in a dental office. Nine patients with different ages, body masses, and medical conditions benefited from the training. No complications were associated with IV conscious sedation in the dental office.</p><p><strong>Conclusion: </strong>This was the first successful \"hands-on\" training on IV conscious sedation provided to OMSs in Tanzania. It laid the foundation for the sustainable care of patients with special needs requiring oral health-related care in the country.</p>","PeriodicalId":15634,"journal":{"name":"Journal of Dental Anesthesia and Pain Medicine","volume":"23 2","pages":"83-89"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ba/cc/jdapm-23-83.PMC10079765.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9278965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"‘LIFE-CHANGING BUBBLES’- How Carbonated Water Can Relieve Swallowing Problems for Many Dysphagia Sufferers Worldwide","authors":"","doi":"10.33140/japm.08.02.02","DOIUrl":"https://doi.org/10.33140/japm.08.02.02","url":null,"abstract":"Today, there are said to be some 590 million people of all ages around the world, who are suffering from a range of swallowing problems – probably about 4 million in the UK, either living at home or as residents in some 20,000 Care Homes, with perhaps another 25,000 as patients in hospital every day. Professor David Smithard, of the Lewisham and Greenwich NHS Trust, has been leading a national campaign for some years to raise the general awareness of Dysphagia and to improve the treatment of patients with varying conditions. He and his team at the Queen Elizabeth Hospital have now completed a detailed Review of the use of carbonated water (CW) in the treatment of Dysphagia, which has just been published and can be accessed here: https://www.mdpi.com/2308-3417/8/1/6 The Review concludes that further evidence-based research is essential before CW can be adopted as standard in clinical practice – but that although the amount of evidence is small, there is a suggestion that swallows are safer and that secretion management improves, and consequently, until further studies are undertaken, Carbonated Water should be limited to individual patient use. My experience as a Dysphagia sufferer is that the use of CW has resulted in life-changing benefits, and this paper is devoted to describing how CW worked for me, and what the practical requirements are, so that many others may be able to benefit as I have done. The paper has three sections: My Personal Experience, Practical Considerations and Conclusions","PeriodicalId":15634,"journal":{"name":"Journal of Dental Anesthesia and Pain Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135081080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Emil Adolf von Behring and his contribution to medicine in the reflection of collectibles","authors":"","doi":"10.33140/japm.08.01.08","DOIUrl":"https://doi.org/10.33140/japm.08.01.08","url":null,"abstract":"The article presents the materials of a study devoted to the scientific activities of the world-famous microbiologist and bacteriologist, the winner of the first Nobel Prize for medicine, Emil Adolf von Bering, presented in the reflection of the world philately and other means of collecting.","PeriodicalId":15634,"journal":{"name":"Journal of Dental Anesthesia and Pain Medicine","volume":"222 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136292971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}