Journal of Education Science最新文献

{"title":"Indirect Spectrophotometric Determination of Cefalexin monohydrate, Ceftriaxone Sodium and Cefotaxim Sodium in Pharmaceuticals Using N-Bromosuccinimde and Evans Blue Dye","authors":"mohamed thamer aghwan, Elham Sadullah Al-talibi","doi":"10.33899/edusj.2019.125959.1009","DOIUrl":"https://doi.org/10.33899/edusj.2019.125959.1009","url":null,"abstract":"An indirect sensitive and selective spectrophotometric method has been developed for the determination of cephalexin monohydrate (CEM) ceftriaxone sodium (CFX) and cefotaxim sodium (CEF) in bulk and pharmaceutical formulation. The method is based on the oxidation of (CEM), (CFX) and (CEF) in hydrochloric acid medium with known excess on N-Bromosuccinimde and subsequent determination of unreacted oxidant by decolorization of Evans blue dye (EB) and measure the absorbance of residual dye at 608 nm. Calibration curves of evans blue dye in the presence of drugs were rectilinear over the ranges 1.0-9.0 , 1.0-8.0 and 1.09.0 μg/ml with molar absorptivity 2.75×10 , 9.28×10 and 7.81×10 l.mol.cm and average recoveries 98.97, 102.08 and 100.08% for CEM, CFX and CEF respectively with RSD of less than 3.29%. The method was free from interference of many excipients and additives commonly found in pharmaceutical formulations. The developed method was successfully applied for determination of the studied drugs in their pharmaceutical formulation resulted in a good agreement with certified value and standard addition procedure.","PeriodicalId":15610,"journal":{"name":"Journal of Education Science","volume":"71 1","pages":"11-31"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84140172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of The Numerical Solution for One Dimensional Drift-Diffusion Model in Silicon in Steady State","authors":"M. Hussien, R. Noori","doi":"10.33899/EDUSJ.2020.127055.1067","DOIUrl":"https://doi.org/10.33899/EDUSJ.2020.127055.1067","url":null,"abstract":"The drift-diffusion model is considered as one of the most important models which is used to describe the characteristics of semiconductor devices and can be applied to wide range of applications started from micro up to nano scale devices after applying the suitable correction on it. The Poisson, continuity, and current equations are considered as the basic equations for semiconductor devices, these equations are partial differential equations, used in the drift diffusion model. These equations described the semiclassical electron and hole transport in semiconductor in the presence of uniformly applied electric field. In this paper a numerical method (finite difference method) has been used to find the solution of these equations depending on Gummel method and Scharfetter-Gummel scheme, the drift diffusion model is applied after many approximation and suitable boundary condition which has been considered for the pn diode in both equilibrium and non-equilibrium cases at room temperature, from this simulation model a MATLAB program has been prepared to obtained diode parameters as a function of distance at the junction region, these parameters are (conduction band, carrier concentration, electric field and charge density) two diode model has been tested with different doping concentration the first with NA = ND and the second with NA > ND also the diode characteristic in the forward biased is obtained. Keyword: simulation of pn diode, drift diffusion model, Gummel method. فا رجنلاا جذومنل يددعلا لحلا ءاصقتسا يئانث يف راشتنلاا pn ذ ي نوكيلسلا يف دحاو دعب را رقتسلاا ةلاح تباث يرون انا زور 1 و نيسح حلاص دمحم زاتمم * 2 1 , 2 ءايزيفلا مسق , ةفرصلا مولعلل ةيبرتلا ةيلك , لصوملا ةعماج قا رعلا ,لصوملا , صخلملا دعي فا رجنا جذومن راشتنا كميو تلاصوملا هابشا طئابن صئاصخ فصول ةمدختسملا جذامنلا مها نم ن نم عساو ىدم ىلع هقيبطت تاقيبطتلا داعبلاا ىلا )ةيوركياملا( ةقيقدلا داعبلاا نم دتمت .اهل ةبسانملا تاحيحصتلا لاخدا دعب ةيونانلا نوساوب ةلداعم ربتعت ، جذومن يف مدختست ةيئزج ةيلضافت تلاداعم يهو تلاصوملا هابشا يف ةيساسلاا تلاداعملا نم رايتلا ةلداعمو ةيرا رمتسلاا ةلداعمو فا رجنلاا هذه فصت .راشتنلاا يجراخ يئابرهك لاجم دوجو لاح يف تاوجفلاو تانورتكللإل يكيسلاكلا ةبش لاقتنلاا تلاداعملا نم .مظت لموك ةقيرط ىلع دامتعلااب تلاداعملا هذهل لولح داجيلإ )ةدودحملا قورفلا ةقيرط( ةيددع ةقيرط قيبطت ثحبلا اذه يف مت Journal of Education and Science (ISSN 1812-125X), Vol: 30, No: 1, 2021 (46-57) Downloaded from https://edusj.mosuljournals.com/ 47 رتفريش ططخمو .لموك فا رجنلاا جذومن قيبطت مت – اشتنلاا ر ، ةبسانم ةيدودح طورش مادختسابو لحلل تابيرقت ةدع ءا رجا دعب يئانث ىلع pn وتلا ةلاح يف اوتلا مدعو نزا .ةفرغلا ةرا رح ةجرد دنع نز ح جمانرب دادعإب ةاكاحم ءا رجا مت ا س و ةغلب يب MATLAB نوكيلسلا يئانثل تاملعم ىلع لوصحلاو pn نم لك ىلع لوصحلا مت ذا .ةفاسملل ةلادك ليصوتلا ةمزح ، تلاماحلا زيكرت ، لاجملا لا ةلاح يف ةفاسملل ةلادك ةنحشلا ةفاثكو يئابرهكلا امدنع يا نزاوت NA = ND امدنع يا نزاوتلا مدع ةلاح يفو NA > ND .نيتلاحلا نيب ةنراقملا تمتو :ةلادلا تاملكلا يئانث ةاكاحم pn نا جذومن ، فارج نا .لموك ةقيرط ","PeriodicalId":15610,"journal":{"name":"Journal of Education Science","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74035362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kinetic and inhibitory study of partially purified lipoxygenase from epilepsy patients serum","authors":"N. Al-lehebe, Ahmed Al-Fayyad","doi":"10.33899/EDUSJ.2020.127778.1093","DOIUrl":"https://doi.org/10.33899/EDUSJ.2020.127778.1093","url":null,"abstract":"This research was included partially purification of lipoxygenase (LOX) from serum of patients with epilepsy using ammonium sulfate precipitation, dialysis and ion-exchange chromatography with specific activity (0.751 U / mg), (0.935 U/mg) and (2.60 U/mg) respectively. Optimum conditions for enzyme activity were determined. The best enzyme activity was showed at 7 minutes of incubation time, 3 minutes of reaction time, pH = 7, temperature 40Co and finally substrate concentration (linoleic acid) was (1.2 mmol/L). By applying Michaelis-Menten and Lineweaver-Burk Equations, Michaelis-Menten constant (km) and Vmax values were found 0.3 (mM) and (0.9 U/ml) respectively. Also this study included the effect of some antiepileptic drugs such as valproic acid, carbamazepine and acetozolamide. Acetazolamide showed the highest inhibition of lipooxygenase activity ( 96.2 )٪ , valproic acid(95.6) and Carbamazapine ( 95.1 )٪ . Inhibition type was studied and the result showed noncompetitive inhibition by using Lineweaver-Burke plot for all above drugs. Keyword: Epilepsy, Lipoxygenase, inhibition, purification, antiepileptic drugs عرصلا ىضرم مد لصم نم ايئزج ىقنملا زينيجيسكواوبيللا ميزنلإ ةيطيبثتو ةيكرح ةسا رد ضايفلا حلاص يلع دمحا * 1 و نيهاش وبع ميها ربا ناوشن 2 1 * ةيبرتلا ةرا زو , ىونين ةظفاحم ةيبرت ةيريدم 2 ءايميكلا مسق , ةفرصلا مولعلل ةيبرتلا ةيلك , لصوملا ةعماج ةصلاخلا موينوملاا تاتيربكب بيسرتلا ةينقت مادختساب عرصلاب نيباصملا ىضرملا مد لصم نم ايئزج زينجيسكواوبيللا ميزنإ ةيقنت ةسا ردلا تنمضت ةيعونلا ةيلاعفلا تناك , ينويلاا لدابتلا ايفا ركوتوموركو يئاشغلا زرفلاو ( 0.751 U/mg ( ) 0.935 U/mg ( ) 2.60 U/mg ) ىلع ظلا تددح .يلاوتلا ناو , نضحلا نمز نم ةعباسلا ةقيقدلا دنع ميزنلال ةيلاعف ىلعا نا جئاتنلا ترهظاو ميزنلاا ةيلاعفل ىلثملا فور ينيجورديهلا سلاا ،قئاقد ثلاث للاخ لعافتلا نمز pH =7.4 ةرا رح ةجرد, 40 oC ( )كيلونيللا ضماح( ساسلاا ةداملا زيكرتو 1.2 سليكيم يتلداعم قيبطتب ,)رتل/لوم يلم رفيونيلاو نتنيم – ىوصقلا ةعرسلاو نوتنيم سلكيم تباث ،كريب 0.3mM و 0.9 U/ ml Journal of Education and Science (ISSN 1812-125X), Vol: 30, No: 1, 2021 (58-71) Downloaded from https://edusj.mosuljournals.com/ 59 .ديملاوزوتيسلاا , نيبا زامابراك , كيوربلاف ضماح لثم عرصلل ةداضملا ريقاقعلا ضعب ريثأت ةسا رد ةسا ردلا تنمضت كلذك . يلاوتلا ىلع ذإ طيبثت ةبسن ىلعا ديملاوزوتيسا راقع رهظا ( 96.2 )٪ اعفل كيوربلاف ضماح ،زينجيسكواوبيللا ميزنا ةيل ( 95.6 )٪ نيبا زامابراكلاو ( 95.1 )٪ ةلداعم مادختساب جئاتنلا ترهظأو طيبثتلا عون ةسا رد تمت . رفيونيل كرب ريقاقعلا عيمجلو يسفانت ريغ طيبثتلا نا هلاعأ . صلل ةداضم ةيودأ ،طيبثت ،ةيقنت , زينجيسكواوبيل , عرصلا : ةلادلا تاملكلا .عر ةمدقملا Introduction رابكو رافطلاا يف اعويش رثكاو رامعلاا عيمجب ثانلااو روكذلا بيصي يزكرملا يبصعلا زاهجلا يف عئاش با رطضا وه عرصلا نسلا [1] )ممعملا(ماعلا عرصلا نيعون ىلا عرصلا فينصت نكميو . Generalized ) يرؤبلا( يئزجلا عرصلاو Focal تابون رثؤت ذإ ايلاخلا نم ةعومجم ىلع ماعلا عرصلا بناج ىلع ايلاخ ةعومجم يف أدبت ام ةداع يرؤبلا عرصلا ةبون اما , غامدلا يبناج لاك يف ابا رطضا ببسي امم غامدلا يف يبصعلا طاشنلا يف طا رفلاا وا نما زتلا وا ذوذشلا قيرط ن","PeriodicalId":15610,"journal":{"name":"Journal of Education Science","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82274675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\" بناء مقياس التبدل الوجداني لطلاب كلية التربية البدنية وعلوم الرياضة في جامعة الموصل\"","authors":"أنوار غانم يحيى الطائي","doi":"10.31185/eduj.vol2.iss40.1621","DOIUrl":"https://doi.org/10.31185/eduj.vol2.iss40.1621","url":null,"abstract":"\u0000بناء مقياس التبدل الوجداني لطلاب كلية التربية البدنية وعلوم الرياضة في جامعة الموصل . \u0000التعرف على مستوى ( درجة ) التبدل الوجداني لطلاب كلية التربية البدنية وعلوم الرياضة في جامعة الموصل . \u0000 \u0000وضع مستويات معيارية لطلاب كلية التربية البدنية وعلوم الرياضة في جامعة الموصل بمقياس التبدل الوجداني . يتم استخدام المنهج الوصفي بالأسلوب المسحي \u0000           يتكون مجتمع البحث من (420) طالب في كلية التربية البدنية وعلوم الرياضة ، أما عينة البناء تشمل (252) طالب يمثلون تقريباً نسبة (60٪) ، إذ تم اختيار (45) طالب من عينة البناء لإجراء التجارب الاستطلاعية للمقياس ويتم استبعادهم من عينة البحث ، و(162) طالب لإجراء صدق البناء (التحليل ألإحصائي للفقرات) (عينة التمييز) ، و(45) طالب لاستخراج معامل الثبات ، ويتم استبعادهم من عينة البحث ، أما عينة التطبيق تتكون من (168) طالب يمثلون نسبة (40٪) من عينة البحث . \u0000يتم استخدام مقياس التبدل الوجداني كأداة لجمع البيانات \u0000  أما إجراءات البناء فهي : ( تحديد أبعاد المقياس ، تحديد أسلوب صياغة فقرات المقياس، صياغة فقرات كل بعد بصورتها الأولية ، فضلاً عن اعتماد الخطوات والإجراءات العلمية في بناء المقاييس والمتضمنة بصدق المحتوى والصدق الظاهري للمقياس وصدق البناء المتمثل (بالتحليل الإحصائي للفقرات ) بأسلوبي المجموعتين المتضادتين والاتساق الداخلي ,  ويتم استخدام طريقة التجزئة النصفية في الثبات . \u0000الوسائل الإحصائية المستخدمة ( المتوسط الحسابي،المنوال،الانحراف المعياري معادلة معامل الالتواء لـ( كارل بيرسون)،معامل الارتباط البسيط،اختبار(t)،المتوسط الفرضي للمقياس، النسبة المئوية ) .","PeriodicalId":15610,"journal":{"name":"Journal of Education Science","volume":"29 1","pages":"293-312"},"PeriodicalIF":0.0,"publicationDate":"2020-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80517703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathophysiological consequences of SARS CoV-2","authors":"H. Hameed, Hiyam N. Maty, F. Isihak","doi":"10.33899/EDUSJ.2020.127225.1089","DOIUrl":"https://doi.org/10.33899/EDUSJ.2020.127225.1089","url":null,"abstract":"","PeriodicalId":15610,"journal":{"name":"Journal of Education Science","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79594797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histopathological changes that induced by Monsodium glutamate and Sodium nitrite on the eyes of white mice Mus musculus and the protective role of Grape seeds oil","authors":"S. Al-Thanoon, A. Ashgar","doi":"10.33899/EDUSJ.2020.127648.1091","DOIUrl":"https://doi.org/10.33899/EDUSJ.2020.127648.1091","url":null,"abstract":"","PeriodicalId":15610,"journal":{"name":"Journal of Education Science","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83996072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spectrophotometric Determination of Salbutamol Sulphate and Mefenamic Acid Using Azur-A Dye in Presence of Oxidizing Agent N-bromosuccinimide","authors":"Subhi Jarullah, Asmaa Hamza Abbas Al-Hashemi","doi":"10.33899/edusj.2020.127113.1072","DOIUrl":"https://doi.org/10.33899/edusj.2020.127113.1072","url":null,"abstract":"A simple, accurate and sensitive indirect spectrophotometric method has been developed for the determination of salbutamol sulphate and mefenamic acid in pure forms and in pharmaceutical preparations (capsule, syrup, tablet). This method based on the bromination of the drug with Nbromosuccinimide in acidic medium and the unreacted oxidizing agent react with constant amount of Azur-A dye solution due to bleach their colour and measured the absorbance of the residual colour dye at 606.5 nm.The molar absorptivity for salbutamol sulphate and mefenamic acid are 2.3 × 10 L.mol .cm and 8.1× 10 L.mol.cm respectively. Beer's Law was obeyed over the concentration range of 1.6 -12.8 μg/ml for salbutamol sulphate and1.6 -13.6 μg/ml for mefenamic acid. The limit of detection (LOD) were 0.0367μg/ml and limit of quantitation (LOQ) were 0.1226 μg/ml for both drugs. In addition, the recovery levels of the drugs were in the range 100.56% and 100.74%. The method was created to be simple, cost-effective and rapid because it does not involve any solvent extraction. The developed method was successfully applied for the determination of the studied drugs.","PeriodicalId":15610,"journal":{"name":"Journal of Education Science","volume":"29 1","pages":"222-244"},"PeriodicalIF":0.0,"publicationDate":"2020-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75502314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Some Antioxidants Compounds on Enzymatic and Nonenzymic Browning of Quince Juice During Thermal Treatment","authors":"A. I. Rashan, O. Al-Abbasy","doi":"10.33899/edusj.2020.127190.1078","DOIUrl":"https://doi.org/10.33899/edusj.2020.127190.1078","url":null,"abstract":"Enzymatic browning by tyrosinase and nonenzymatic browning (Maillard reaction) are responsible for producing new compounds which contributes considerably to the undesirable of aroma, taste and colour in food . In this study, tyrosinase activity and browning intensity in quince juice were inhibited by treating them with antioxidant compounds vanillin, glutathione and melatonin as compared to the control. The maximum inhibition percentage of Tyrosinase were 83, 68.8 and 90.3 % and the maximum inhibitory effect of browning intensity were 13.9, 9.7 and 29.8% respectively. For untreated quince juice which heated to 5 hours at 100 C, the results showed increasing in A294, Browning intensity (A420) and reducing power, as well as decreasing in reducing sugar, free amino group, phenolic compounds contents and inhibition percentage of lipid peroxidation. The decreasing of A294, browning intensity and increasing in reducing power were showed after treating with (10mM) vanillin and (8mM) glutathione compared to control. Conversely to glutathione, the addition of vanillin to quince juice revealed increasing in inhibition percentage of lipid peroxidation, reducing sugar and phenolic contents and decreasing in free amino acid content compared to control. Inhibition Mode of tyrosinase by melatonin was noncompetitive. The Km value remained constant (1.96mM), while Vmax reduced from 228.13 to 114.06 U.ml.min. Inhibition constant Ki value was 6.9 mM.","PeriodicalId":15610,"journal":{"name":"Journal of Education Science","volume":"84 1","pages":"206-221"},"PeriodicalIF":0.0,"publicationDate":"2020-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73546329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study of Optical Properties of Tetraborate Glasses Containing CaO, MgO & BaO","authors":"A. Kamal, Manaf A.Hassan al-azzawi","doi":"10.33899/EDUSJ.2020.127127.1076","DOIUrl":"https://doi.org/10.33899/EDUSJ.2020.127127.1076","url":null,"abstract":"Abstract Glasses with compositions (100-x) % Na2B4O7–x % MO (X=10,20,30,40) where (M) is Ba, Mg and Ca, are prepared using conventional melt quenching method. X-rays diffractions are performed. The result of (XRD) confirm the amorphous nature of the samples. The measured density increases with increasing content of BaO, MgO & CaO in glass network. The position and shifting rate of absorption edge, optical band energy (Eopt) and band tails energy (Eo) were investigated. The Eopt and Eo values of all glasses studied in this work were found to be comparable with the values corresponding to some semiconductors. The structure of the glasses was investigated by means of IR spectroscopy. It found from the experimental results of IR spectra that the groups (BO3) and (B2O7) are dominant the structure of these glasses. Also It is found that the shifting in band position is small with increasing of (Ba, Mg, Ca) oxide in the glass network.","PeriodicalId":15610,"journal":{"name":"Journal of Education Science","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84190483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of Some Heterocyclic Compounds Derived From 2-Amino Benzothiazole","authors":"Zainab Muataz Mahmood, A. K. Ahmad","doi":"10.33899/edusj.2020.127562.1087","DOIUrl":"https://doi.org/10.33899/edusj.2020.127562.1087","url":null,"abstract":"In this paper , number of heterocyclic compound with five and six membered, Such as substituted imidazole, triazin and thiazolidine. The compound N-(1,3benzothiazol-2-yl)-2-chloro acetamide was prepared from the reaction of the 2-amino benzothiazole with chloroacetyl chloride. The product N-(1,3-benzothiazol -2-yl) -2chloro acetamide was reacted with thiourea and urea to prepare both 4-(1.3benzothiazol -2-yl amino) -1,5-dihydro -2H-imidazole -2-thione and 4-(1,3benzothiazol -2-yl amino) -1,5-dihydro -2H-imidazol -2-one, respectively. As did compound N-(1,3-benzothiazol -2-yl) -2-chloro acetamide with thiosemicarbazide and semicarbazide to prepared the two compounds 5-(1,3-benzothiazol -2-yl amino) 1,6-dihydro -1,2,4-triazine -3(2H)-thione and 5-(1,3-benzothiazol -2-yl amino) -1,6dihydro -1,2,4-triazine -3(2H)-one, respectively. Also compound N-(1,3-benzothiazol -2-yl) -2-chloro acetamide with ammonium thiocyanate to prepare the compound 3(1,3-benzothiazol -2-yl amino) thiazolidin -4-one. From the reaction of compound N(1,3-benzothiazol -2-yl) -2-chloro acetamide with phenyl thiourea attended 4-(1,3benzothiazol -2-yl amino) -1-phenyl -1,5 -dihydro 2H-imidazole -2-thio. Also from the reaction of 2-amino benzothiazole with phthalic anhydride or malic anhydride attended compounds2(1,3-benzothiazol -2-yl carbonyl) benzoic acid and 4-(1,3benzothiazol -2-yl amino) -4-oxobut-2-enoic acid and 2-(1H-benzoimidazol -2-yl) –N-(1,3-benzothiazol -2-yl) benzamide and 3-(1Hbenzoimidazol -2-yl) –N-(1,3-benzothiazol -2-yl) acrylamide, respectively. And by reaction compound 2(1,3-benzothiazol -2-yl carbonyl) benzoic acid and 4-(1,3benzothiazol -2-yl amino) -4-oxobut-2-enoic acid or 2-(1H-benzoimidazol -2-yl) –N(1,3-benzothiazol -2-yl) benzamide and 3-(1H-benzoimidazol -2-yl) –N-(1,3benzothiazol -2-yl) acrylamide with o-phenylene diamine attended compounds 2(1H-benzoimidazol -2-yl) –N-(1,3-benzothiazol -2-yl) benzamide and 3-(1Hbenzoimidazol -2-yl) –N-(1,3-benzothiazol -2-yl) acrylamide, respectively. The synthesized compounds are identified by physical melting points, color change and spectroscopic methods such as IR, proton-NMR.","PeriodicalId":15610,"journal":{"name":"Journal of Education Science","volume":"10 1","pages":"193-205"},"PeriodicalIF":0.0,"publicationDate":"2020-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80122555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}