Journal of electrocardiology最新文献

{"title":"Can the efficacy of a medical treatment be predicted based on the type of idiopathic premature ventricular contraction?","authors":"Adem Atici M.D. ,&nbsp;Irfan Sahin M.D. ,&nbsp;Ömer Doğan M.D. ,&nbsp;Hasan Ali Barman M.D. ,&nbsp;Ayhan Kup M.D. ,&nbsp;Mehmet Celik M.D. ,&nbsp;Ahmet Demirkiran M.D. ,&nbsp;Yusuf Yilmaz M.D. ,&nbsp;Fatma Betul Ozcan M.D. ,&nbsp;Erdem Cevik M.D. ,&nbsp;Hüseyin Orta M.D. ,&nbsp;Mustafa Yılmaz M.D. ,&nbsp;Ali Ugur Soysal M.D. ,&nbsp;Mehmet Tugay Yumuk M.D. ,&nbsp;Sevil Tugrul Yavuz M.D. ,&nbsp;Fatih Öztürk M.D. ,&nbsp;Medeni Karaduman M.D. ,&nbsp;İshak Yilmaz M.D. ,&nbsp;Mustafa Caliskan","doi":"10.1016/j.jelectrocard.2024.153782","DOIUrl":"10.1016/j.jelectrocard.2024.153782","url":null,"abstract":"<div><h3>Background</h3><p>Premature ventricular contractions (PVCs) are common arrhythmias with diverse clinical implications. This retrospective study aimed to evaluate the efficacy of medical treatments using various clinical, imaging, and electrocardiographic parameters in patients with idiopathic PVCs.</p></div><div><h3>Methods</h3><p>A total of 1051 patients with idiopathic PVCs were retrospectively analyzed. Patients were categorized into three groups based on treatment response: beta-blocker (BB) responders (479 patients), calcium-channel blocker (CCB) responders (335 patients), and class 1c antiarrhythmic (AA) responders (237 patients). Clinical, imaging, and electrocardiographic data were collected and analyzed to assess the factors influencing treatment response.</p></div><div><h3>Results</h3><p>Age, left ventricular ejection fraction (LVEF), PVC QRS duration, CI variability, and multiple PVC morphologies were identified as significant factors affecting treatment response. Older age and lower LVEF were associated with better response to BB treatment, whereas CCB responders showed narrower QRS complexes. BB responders also exhibited higher CI variability, possibly linked to automaticity mechanisms. Moreover, the BB responder group had a higher frequency of multiple PVC morphologies.</p></div><div><h3>Conclusion</h3><p>These findings emphasize the importance of tailored treatment approaches based on individual patient characteristics.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"86 ","pages":"Article 153782"},"PeriodicalIF":1.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142097434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The assessment of adolescent obesity's effects on ventricular repolarization","authors":"","doi":"10.1016/j.jelectrocard.2024.06.045","DOIUrl":"10.1016/j.jelectrocard.2024.06.045","url":null,"abstract":"<div><h3>Background</h3><p>Currently, there is a lack of research on the Tp-Te interval and Tp-e/QT ratio in obese adolescents who have metabolic syndrome.</p></div><div><h3>Aim</h3><p>Our study aims to compare established ventricular repolarization<span><span> parameters with these intervals and ratios in obese adolescents with or without metabolic syndrome, alongside a healthy control group, while exploring the association of these </span>repolarization parameters with cardiovascular risk factors and echocardiographic variables.</span></p></div><div><h3>Methods</h3><p>The study included 100 obese adolescents and 50 lean subjects, with the obese participants categorized into two subgroups. The Tp-Te interval was identified as the duration from the peak to the end of the T wave.</p></div><div><h3>Results</h3><p>The metabolic and non-metabolic syndrome obese groups exhibited significantly elevated QTc and TpTe values compared to the control group, with no statistically significant differences observed in minimum QT, maximum QT, QT dispersion<span>, QTc dispersion, TpTe dispersion, and TpTe/QT ratio values among obese subjects with metabolic or non-metabolic syndrome and controls. Specifically, TpTe values were significantly elevated in the non-metabolic syndrome obese groups compared to controls, while minimum TpTe values were significantly elevated in the metabolic syndrome obese groups compared to controls, and the prolongation of the QTc interval was notably elevated in the obese groups than in controls.</span></p></div><div><h3>Conclusions</h3><p>Obese adolescents demonstrated an elevated TpTe interval compared to healthy controls, without any significant differences observed in TpTe dispersion, and TpTe/QT ratio values between the two groups. Results of our study showed that a negative correlation between TpTe and HDL-cholesterol and a positive correlation between the TpTe/QT ratio and insulin sensitivity indices in adolescents with metabolic syndrome.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"86 ","pages":"Article 153755"},"PeriodicalIF":1.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141600178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of parametric B-spline and Hermite cubic spline based methods for accurate ECG signal modeling","authors":"Alka Mishra,&nbsp;Surekha Bhusnur,&nbsp;Santosh Kumar Mishra,&nbsp;Pushpendra Singh","doi":"10.1016/j.jelectrocard.2024.153783","DOIUrl":"10.1016/j.jelectrocard.2024.153783","url":null,"abstract":"<div><p>Analyzing Electrocardiogram (ECG) signals is imperative for diagnosing cardiovascular diseases. However, evaluating ECG analysis techniques faces challenges due to noise and artifacts in actual signals. Machine learning for automatic diagnosis encounters data acquisition hurdles due to medical data privacy constraints. Addressing these issues, ECG modeling assumes a crucial role in biomedical and parametric spline-based methods have garnered significant attention for their ability to accurately represent the complex temporal dynamics of ECG signals. This study conducts a comparative analysis of two parametric spline-based methods—B-spline and Hermite cubic spline—for ECG modeling, aiming to identify the most effective approach for accurate and reliable ECG representation. The Hermite cubic spline serves as one of the most effective interpolation methods, while B-spline is an approximation method. The comparative analysis includes both qualitative and quantitative evaluations. Qualitative assessment involves visually inspecting the generated spline-based models, comparing their resemblance to the original ECG signals, and employing power spectrum analysis. Quantitative analysis incorporates metrics such as root mean square error (RMSE), Percentage Root Mean Square Difference (PRD) and cross correlation, offering a more objective measure of the model's performance. Preliminary results indicate promising capabilities for both spline-based methods in representing ECG signals. However, the analysis unveils specific strengths and weaknesses for each method. The B-spline method offers greater flexibility and smoothness, while the cubic spline method demonstrates superior waveform capturing abilities with the preservation of control points, a critical aspect in the medical field. Presented research provides valuable insights for researchers and practitioners in selecting the most appropriate method for their specific ECG modeling requirements. Adjustments to control points and parameterization enable the generation of diverse ECG waveforms, enhancing the versatility of this modeling technique. This approach has the potential to extend its utility to other medical signals, presenting a promising avenue for advancing biomedical research.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"86 ","pages":"Article 153783"},"PeriodicalIF":1.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142097524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atypical Aslanger pattern in inferolateral myocardial infarction – A new variant to look out for?","authors":"Ashok Victor,&nbsp;Nageshwaran P.M.,&nbsp;Tamilselvan K.,&nbsp;Nihal Sheriff","doi":"10.1016/j.jelectrocard.2024.153786","DOIUrl":"10.1016/j.jelectrocard.2024.153786","url":null,"abstract":"<div><p>We report a case of a 53-year-old male with inferolateral myocardial infarction, presenting an atypical Aslanger pattern on electrocardiogram (ECG). The ECG showed ST elevation in leads III, aVR, aVF, and posterior leads, with ST depression in II and V2-V6 with terminal positive T waves. Coronary angiography revealed total occlusion of the left circumflex artery (LCx) with significant stenosis of the left anterior descending (LAD) and right coronary artery (RCA). The LCx was successfully revascularized. This case highlights the importance of recognizing atypical Aslanger patterns, which may indicate multivessel coronary artery disease.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"87 ","pages":"Article 153786"},"PeriodicalIF":1.3,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142150757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accelerated idioventricular rhythm after left bundle branch pacing lead implantation","authors":"Yoji Iida ,&nbsp;Junzo Inamura","doi":"10.1016/j.jelectrocard.2024.153788","DOIUrl":"10.1016/j.jelectrocard.2024.153788","url":null,"abstract":"<div><p>Premature ventricular contractions with right bundle branch block morphology induced during left bundle branch (LBB) pacing (LBBP) lead implantation serve as a marker indicating that the lead is close to or has reached the LBB region. However, no reports to date have described accelerated idioventricular rhythm (AIVR) induced by LBBP lead deployment.</p><p>We herein describe a patient who underwent LBBP for complete atrioventricular block. The patient's intrinsic escape rhythm was overtaken by AIVR induced immediately after LBBP lead deployment.</p><p>AIVR is another marker indicating that the lead has reached the LBB region.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"87 ","pages":"Article 153788"},"PeriodicalIF":1.3,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relevance of accurate QT correction in the assessment of long QT syndrome","authors":"Matias Kanniainen ,&nbsp;Teemu Pukkila ,&nbsp;Katriina Aalto-Setälä ,&nbsp;Esa Räsänen","doi":"10.1016/j.jelectrocard.2024.153790","DOIUrl":"10.1016/j.jelectrocard.2024.153790","url":null,"abstract":"<div><h3>Background</h3><p>Long QT syndrome (LQTS) is a genetic cardiac disease, where the corrected QT (QTc) interval is prolonged. It can cause arrhythmias and lead to a sudden cardiac death. Duration of the QT interval depends on the heart rate and this dependency is treated with QT correction. However, the current QT correction methods have well known problems and limitations.</p></div><div><h3>Objective</h3><p>We study the relevance of QT correction method in evaluating the risk of LQTS. We evaluate the reliability of the present and recently developed QT correction methods to discriminate LQTS subjects from healthy controls.</p></div><div><h3>Methods</h3><p>We use the clinically prevalent QT correction methods, particularly Bazett and Fridericia, in comparison with the recently developed AccuQT method. The data of healthy controls and LQTS subjects is extracted from the Rochester THEW database. The analysis accounts for sex, major LQTS subtypes, and beta-blocker treatment.</p></div><div><h3>Results</h3><p>QT values corrected with AccuQT discriminate the healthy and LQTS samples with the best accuracy, leading to (TP, TN) = (0.87, 0.65) with the conventional 450 ms threshold for LQTS. Fridericia correction yields lower sensitivity (0.71), but comparable balanced accuracy, whereas Bazett shows significantly less accurate results due to overcorrection at lower heart rates.</p></div><div><h3>Conclusion</h3><p>The selected QT correction method is important in the identification of LQTS. In particular, the use of Bazett correction should be questioned. Fridericia correction yields good results with respect to its simplicity. AccuQT has the best accuracy out of all the methods for LQTS discrimination. For practical applicability, however, AccuQT needs further validation in realistic clinical conditions.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"87 ","pages":"Article 153790"},"PeriodicalIF":1.3,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0022073624002607/pdfft?md5=9d58db9cf66077320d62f5c225845794&pid=1-s2.0-S0022073624002607-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142130183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genesis of ischemic ST segment changes: A study using precordial bipolar leads and regional vectorcardiograms","authors":"Mario J. Mc Loughlin MD","doi":"10.1016/j.jelectrocard.2024.153789","DOIUrl":"10.1016/j.jelectrocard.2024.153789","url":null,"abstract":"<div><h3>Background</h3><p>Precordial Bipolar Leads (PBLs), Weighted Unipolar Leads (WUL), and Regional Vectorcardiograms (RVCGs) are constructed using the same data recorded by a standard 12‑lead ECG, but they provide additional information not visible in the standard 12‑lead ECG (ECG) tracings.</p></div><div><h3>Objectives</h3><p>In previous studies during balloon occlusion of the LAD and RCA, we observed a complete ischemic inversion of the QRS waves, with folding of the loop and ST segment shift. In the present study, we aim to investigate this abnormality using new ECG methods. We hypothesize that utilizing PBL, WUL, and RVCG in patients with ischemia caused by total acute coronary artery occlusion enables the detection of specific abnormalities—such as changes in waveform time/amplitude, the presence of the omega sign, distortion and folding of RVCG loops, and alterations in loop direction in both the transverse and frontal planes—that are not easily discernible with a standard 12‑lead ECG. This enhanced detection aids in understanding the mechanisms underlying electrocardiographic changes and may assist in managing patients when diagnostic uncertainties arise.</p></div><div><h3>Methods</h3><p>Thirty-three patients undergoing elective PTCA were studied before and after acute LAD (16 patients) or RCA (17 patients) occlusion, and their data were processed with new methods based on PBLs, WULs, and RVCGs.</p></div><div><h3>Results</h3><p>1. In acute ischemia due to occlusion of the LAD and RCA, the most important current of injury occurs in the right to left axis. This axis is underestimated by the standard 12‑lead ECG and only partially complemented by leads V3R and V4R. 2. The two-dimensional presentation detects a new sign (the omega sign), not detectable in the classic ECG, but almost always present in ischemia. It also allows for an accurate identification of the J point. 3. Ischemic R wave peak delay results in distortion and folding of the RVCG loop and causes displacement of the J point and the ST segment. 4. Wave inversion changes the loop direction in the transverse and frontal plane.</p></div><div><h3>Conclusions</h3><p>Precordial bipolar leads, weighted unipolar leads, and regional vectorcardiograms provide essential information omitted by the standard 12‑lead ECG.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"87 ","pages":"Article 153789"},"PeriodicalIF":1.3,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142122666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of electrocardiographic criteria for predicting left ventricular hypertrophy and dilation in presence of left bundle branch block","authors":"Ashley DeBauge ,&nbsp;Christopher J. Harvey ,&nbsp;Amulya Gupta ,&nbsp;Tyan Fairbank ,&nbsp;Sagar Ranka ,&nbsp;Sania Jiwani ,&nbsp;Madhu Reddy ,&nbsp;Seth H. Sheldon ,&nbsp;Amit Noheria","doi":"10.1016/j.jelectrocard.2024.153787","DOIUrl":"10.1016/j.jelectrocard.2024.153787","url":null,"abstract":"<div><h3>Background</h3><div>The utility of standard published electrocardiographic (ECG) criteria for left ventricular hypertrophy (LVH) in patients with left bundle branch block (LBBB) is not established. We have previously shown that in ECGs demonstrating LBBB, QRS duration outperforms vectorcardiographic X, Y, Z lead and root-mean-squared (3D) amplitudes and voltage-time-integrals in diagnosing LVH and dilation. We sought to evaluate diagnostic yields of published LVH criteria versus QRS duration for ECG based diagnosis of LVH and dilation in presence of LBBB.</div></div><div><h3>Methods</h3><div>We included adult patients with typical LBBB having ECG and transthoracic echocardiogram performed within 3 months of each other in 2010–2020. We obtained area under receiver-operator characteristic curve (AUC) for QRS duration and each of the published ECG LVH criteria to predict increased LV mass indexed (↑LVMi, women &gt;95 g/m², men &gt;115 g/m²) and LV end diastolic volume indexed (↑LVEDVi, women &gt;61 mL/m², men &gt;74 mL/m²).</div></div><div><h3>Results</h3><div>Among 413 adults (53 % women, age 73 ± 12 yr) with LBBB, the traditional LVH criteria performed poorly to detect ↑LVMi or ↑LVEDVi. Cornell voltage-duration product had the highest AUCs (↑LVMi 0.634, ↑LVEDVi 0.580). QRS duration had a higher AUC for diagnosing ↑LVMi (women 0.657, men 0.703) and ↑LVEDVi (women 0.668, men 0.699) compared to any other criteria.</div></div><div><h3>Conclusions</h3><div>In patients with LBBB, prolonged QRS duration (women ≥150 ms, men ≥160 ms) is a superior predictor of LVH and dilation than traditional ECG-based LVH criteria.</div></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"87 ","pages":"Article 153787"},"PeriodicalIF":1.3,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142347925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abnormal QRS-T angles in 5796 women and men aged 50–64: an electrocardiographic analysis providing mechanistic insights","authors":"Lennart Bergfeldt ,&nbsp;Rut Hellsing ,&nbsp;David Molnar ,&nbsp;Amar Taha ,&nbsp;Gunilla Lundahl ,&nbsp;Lennart Gransberg ,&nbsp;Göran Bergström","doi":"10.1016/j.jelectrocard.2024.153784","DOIUrl":"10.1016/j.jelectrocard.2024.153784","url":null,"abstract":"<div><h3>Introduction</h3><p>Abnormal QRS-T angles are prognostic markers for cardiovascular deaths including sudden cardiac death. They occur in ∼5–6% of population-based cohorts but in ∼20% of patients with diabetes. The mechanistic background, electrical activation and/or recovery disturbances, is not known and the topic of this study.</p></div><div><h3>Methods</h3><p>Applying Frank vectorcardiography (VCG) and simultaneously recorded scalar 12‑lead ECG, electrical activation and recovery of abnormal QRS-T angles were studied in 311 participants (5.4%) from a population-based cohort of 5796 women and men in the main Swedish CArdio-Pulmonary bio-Imaging Study (SCAPIS) in Gothenburg. Cut-off values for the peak and mean QRS-T angles were &gt; 124° and &gt; 119°, based on the &gt;95th percentile among all 1080 participants in the pilot SCAPIS and reference values for normal directions (Q1-Q3) from 319 apparently healthy (30%) of them.</p></div><div><h3>Results</h3><p>Of 311 cases 17% had known cardiac disease. Deviations of QRS and QRSarea-vectors from reference limits (90%) were significantly more common than deviations of T- and Tarea-vectors (65%). Standard ECG signs suggested pathophysiology in 20%; left bundle branch block (LBBB) and voltage criteria for left ventricular hypertrophy being most frequent (9–10%) each. Sub-group analysis of the 30 with LBBB showed very large variability in vector directions.</p></div><div><h3>Conclusions</h3><p>Our observations provide mechanistic insights about abnormal QRS-T angles of potential value for future prognostic and interventional studies. The results also have potential implications for LBB area pacing and the approach to left ventricular hypertrophy.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"86 ","pages":"Article 153784"},"PeriodicalIF":1.3,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0022073624002541/pdfft?md5=f5c71d666db9c85a4e70485ea8a0b707&pid=1-s2.0-S0022073624002541-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142080508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The syndrome of inferior non-infarctional Q-waves due to segmental basal left ventricular hypertrophy","authors":"John E. Madias","doi":"10.1016/j.jelectrocard.2024.153785","DOIUrl":"10.1016/j.jelectrocard.2024.153785","url":null,"abstract":"<div><p>Non-infarctional Q-waves in general are often recorded in the ECG, and are attributed to anatomical and electrical ECG axis shifts, presence of accessory pathways, pregnancy, HCM, and other HCM-like segmental LV myocardial hypertrophic states, that are currently not fully characterized, as to their nosological nature. The present focused review concerns in particular inferior Q-waves and their association with segmental basal anterior and/or septal LV hypertophies due to HCM, and other not yet fully characterized basal segmental LV hypertophies. Insights from the currently available literature on the topic are reviewed, and varying opinions about the nature of such hypertophic states are discussed, with some suggestions, for what is needed to be done, for their further pathlogenetic characterization.</p></div>","PeriodicalId":15606,"journal":{"name":"Journal of electrocardiology","volume":"86 ","pages":"Article 153785"},"PeriodicalIF":1.3,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142083789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}