Journal of Diabetes & Metabolic Disorders最新文献_第4页

Long-term effects of a telemedically-assisted lifestyle intervention on glycemic control in patients with type 2 diabetes – A two-armed randomised controlled trial in Germany 远程医疗辅助生活方式干预对2型糖尿病患者血糖控制的长期影响——德国的一项双臂随机对照试验

Journal of Diabetes & Metabolic Disorders Pub Date : 2023-10-25 DOI: 10.1007/s40200-023-01290-6

Annalena Dunkel, Katja von Storch, Martin Hochheim, Susanne Zank, M. Cristina Polidori, Christiane Woopen

{"title":"Long-term effects of a telemedically-assisted lifestyle intervention on glycemic control in patients with type 2 diabetes – A two-armed randomised controlled trial in Germany","authors":"Annalena Dunkel, Katja von Storch, Martin Hochheim, Susanne Zank, M. Cristina Polidori, Christiane Woopen","doi":"10.1007/s40200-023-01290-6","DOIUrl":"https://doi.org/10.1007/s40200-023-01290-6","url":null,"abstract":"Abstract Purpose Diabetes is considered one of the fastest growing diseases worldwide. Especially in the treatment of type 2 diabetes, lifestyle interventions have proven to be effective. However, long-term studies in real-world contexts are rare, which is why further research is needed. The aim of the present study is to investigate whether effects achieved in the context of a long-term lifestyle intervention can be sustained by patients in the long term. Methods In a two-arm randomized trial we compared diabetes care as usual to a lifestyle intervention combining telemedically support and individual needs-based telephone coaching. The study included 151 patients with type 2 diabetes randomized to either the intervention or control group. Intervention Group (IG; N = 86, 80.2% male, mean age: 59.7) received telemedical devices and telephone coaching over a period of 12 months, Control Group (CG; N = 65, 83.1% male, mean age: 58,8) received care as usual. The primary outcome was chance in Hb A1c . A follow-up survey was conducted after 24 months. Results The intervention group showed significantly better HbA1c- values compared to the control group at both 12 and 24 months (12 M: − 0.52 (-0.73; − 0.32), p < .000; 24 M: − 0.38 (-0.61; − 0.15), p = .001). The strongest change was seen in the first three months, with the best value obtained at 6 months and stable thereafter. Conclusion Combined telephone coaching with telemedicine support could lead to better long-term glycemic control in people with type 2 diabetes. In the future, more long-term studies should be conducted in real-world settings and lifestyle interventions should be offered more widely.","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"2 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134973192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A methodological quality review of citations of randomized controlled trials of diabetes type2 in leading clinical practice guidelines and systematic reviews 主要临床实践指南和系统评价中2型糖尿病随机对照试验引用的方法学质量评价

Journal of Diabetes & Metabolic Disorders Pub Date : 2023-10-19 DOI: 10.1007/s40200-023-01328-9

Azadeh Aletaha, Mohammad-Reza Malekpour, Abbas Ali Keshtkar, Hamid Reza Baradaran, Shahram Sedghi, Yasaman Mansoori, Mehdi Hajiani, Somayeh Delavari, Farzaneh Habibi, Maryam Razmgir, Saeedeh Saeedi, Akbar Soltani, Leila Nemati-Anaraki

引用次数: 0

Polyphenols mediated attenuation of diabetes associated cardiovascular complications: A comprehensive review 多酚介导的糖尿病相关心血管并发症的衰减:一项全面的综述

Journal of Diabetes & Metabolic Disorders Pub Date : 2023-10-18 DOI: 10.1007/s40200-023-01326-x

Navdeep Kour, Gulshan Bhagat, Simran Singh, Sandip Singh Bhatti, Saroj Arora, Balbir Singh, Astha Bhatia

引用次数: 0

Association between pre-diabetes or diabetes and cognitive impairment in a community-dwelling older population: Bushehr Elderly Health (BEH) program 社区居住老年人糖尿病前期或糖尿病与认知障碍的关系:布什尔老年健康(BEH)项目

Journal of Diabetes & Metabolic Disorders Pub Date : 2023-10-18 DOI: 10.1007/s40200-023-01325-y

Sara Farkhani, Moloud Payab, Farshad Sharifi, Yasaman Sharifi, Sammy Mohammadi, Zhaleh Shadman, Noushin Fahimfar, Ramin Heshmat, Alireza Hadizadeh, Gita Shafiee, Iraj Nabipour, Farnaz Tavakoli, Bagher Larijani, Mahbube Ebrahimpur, Afshin Ostovar

引用次数: 0

Electrospun skin dressings for diabetic wound treatment: a systematic review 电纺敷料用于糖尿病伤口治疗:系统综述

Journal of Diabetes & Metabolic Disorders Pub Date : 2023-10-17 DOI: 10.1007/s40200-023-01324-z

Amanda de Souza, Giovanna E. Santo, Gustavo O. Amaral, Karolyne S. J. Sousa, Julia R. Parisi, Rodrigo B. Achilles, Daniel A. Ribeiro, Ana C. M. Renno

引用次数: 0

Identification of rare variants in candidate genes associated with monogenic diabetes in polish mody-x patients 波兰mody-x患者中与单基因糖尿病相关的候选基因罕见变异的鉴定

Journal of Diabetes & Metabolic Disorders Pub Date : 2023-10-13 DOI: 10.1007/s40200-023-01312-3

Paulina Jakiel, K. Gadzalska, E. Juścińska, M. Gorządek, T. Płoszaj, S. Skoczylas, M. Borowiec, A. Zmysłowska

{"title":"Identification of rare variants in candidate genes associated with monogenic diabetes in polish mody-x patients","authors":"Paulina Jakiel, K. Gadzalska, E. Juścińska, M. Gorządek, T. Płoszaj, S. Skoczylas, M. Borowiec, A. Zmysłowska","doi":"10.1007/s40200-023-01312-3","DOIUrl":"https://doi.org/10.1007/s40200-023-01312-3","url":null,"abstract":"Abstract Purpose Monogenic diabetes (MD) is caused by a mutation in a single gene and accounts for approximately 2.5–6% of all diabetes cases. Maturity-onset diabetes of the young (MODY) is the most common form of MD. To date, 14 different genes have been identified and associated with the presence of MODY phenotype. However, the number of potential candidate genes with relevance to beta cell function and glucose metabolism is increasing as more research is published. The aim of the study was to identify potentially causative variants in selected candidate genes in patients with a clinical diagnosis of MD. Methods Targeted Next-Generation Sequencing (tNGS) on Illumina NextSeq 550 platform involving Agilent SureSelectQXT Target Enrichment protocol for 994 patients with suspected MD was performed. In the next step, the sequencing data of 617 patients with no pathogenic variants in main MD-related genes were reanalysed for the presence of causative variants in six candidate genes ( MTOR, TBC1D4, CACNA1E, MNX1, SLC19A2, KCNH6 ). The presence of the selected variants was confirmed by Sanger sequencing. Results Seven heterozygous possibly damaging variants were identified in four candidate genes ( MTOR, TBC1D4, CACNA1E, MNX1 ). Five changes were assessed as novel variants, not previously described in available databases. None of the described variants were present among patients previously diagnosed with MODY diabetes due to causative, pathogenic variants in known MODY-related genes. Conclusions The results obtained seem to confirm the effectiveness of the NGS method in identifying potentially causative variants in novel candidate genes associated with MODY diabetes.","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135856246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Impact of diabetes on healthcare utilization and expenditure among older adults in India 糖尿病对印度老年人医疗保健利用和支出的影响

Journal of Diabetes & Metabolic Disorders Pub Date : 2023-10-13 DOI: 10.1007/s40200-023-01319-w

Puja Goswami, Abhishek Anand

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The association of osteoporosis and cardiovascular disease risk score based on the Framingham and ACC/AHA risk prediction models: a cross-sectional analysis of Bushehr Elderly Health Program 基于Framingham和ACC/AHA风险预测模型的骨质疏松症与心血管疾病风险评分的关联:Bushehr老年健康计划的横断面分析

Journal of Diabetes & Metabolic Disorders Pub Date : 2023-10-12 DOI: 10.1007/s40200-023-01313-2

Mona Azarakhshi, Bagher Larijani, Noushin Fahimfar, Mohammad Reza Mohajeri Tehrani, Kazem Khalagi, Mohammad Javad Mansourzadeh, Mohammad Amin Khadembashiri, Mahnaz Sanjari, Iraj Nabipour, Afshin Ostovar

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The role of miR-143/miR-145 in the development, diagnosis, and treatment of diabetes miR-143/miR-145在糖尿病的发生、诊断和治疗中的作用

Journal of Diabetes & Metabolic Disorders Pub Date : 2023-10-11 DOI: 10.1007/s40200-023-01317-y

Yousef Rasmi, Yara Ahmed Mohamed, Shahriar Alipour, Salma Ahmed, Samar Samir Abdelmajed

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Effect of metformin (vs. placebo or sulfonylurea) on all-cause and cardiovascular mortality and incident cardiovascular events in patients with diabetes: an umbrella review of systematic reviews with meta-analysis 二甲双胍(与安慰剂或磺脲相比)对糖尿病患者全因死亡率和心血管死亡率以及心血管事件的影响:一项综合系统评价和荟萃分析

Journal of Diabetes & Metabolic Disorders Pub Date : 2023-10-11 DOI: 10.1007/s40200-023-01309-y

Mansour Bahardoust, Sepideh Mousavi, Mohsen Yariali, Meisam Haghmoradi, Farzad Hadaegh, Davood Khalili, Ali Delpisheh

引用次数: 0