{"title":"Microbiota research in Iran; current knowledge and future perspective.","authors":"Hanieh-Sadat Ejtahed, Shirin Hasani-Ranjbar, Ahmad-Reza Soroush, Seyed-Davar Siadat, Bagher Larijani","doi":"10.1007/s40200-020-00703-0","DOIUrl":"10.1007/s40200-020-00703-0","url":null,"abstract":"<p><strong>Objective: </strong>As the gut microbiota has attracted considerable attention in recent years, the aim of the present study is introducing a new microbiota research group at Endocrinology and Metabolism Research Institute (EMRI) that collaborates with national and international research centers for microbiome research projects management.</p><p><strong>Methods: </strong>All the documents from EMRI focused on the microbiota field were collected using PubMed, Scopus, and Web of Science electronic databases from the inception up to June 2020.</p><p><strong>Results: </strong>Findings of the EMRI research projects on the microbiota field were reviewed in this study and we highlighted some specific primary results of gut microbiota composition in the Iranian population. Moreover, applications of the developed Microbiota Database are introduced.</p><p><strong>Conclusion: </strong>Enhancement of investment in this field and interdisciplinary collaborations are needed to progress our knowledge about the Iranian gut microbiota composition and develop microbiota modulating interventions over the next decade.</p>","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"3 1","pages":"1479-1484"},"PeriodicalIF":0.0,"publicationDate":"2021-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11599682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90913076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hilda Samimi, Nooshin Shirzad, Sayed Mahmoud Sajjadi-Jazi, Ramin Heshmat, Mahsa M Amoli, Mohammad Reza Mohajeri-Tehrani, Seyed Mohammad Tavangar, Bagher Larijani, Vahid Haghpanah
{"title":"Thyroid Cancer research at endocrinology and metabolism research institute (EMRI): a report of scientific activities between 2005 and 2020.","authors":"Hilda Samimi, Nooshin Shirzad, Sayed Mahmoud Sajjadi-Jazi, Ramin Heshmat, Mahsa M Amoli, Mohammad Reza Mohajeri-Tehrani, Seyed Mohammad Tavangar, Bagher Larijani, Vahid Haghpanah","doi":"10.1007/s40200-020-00702-1","DOIUrl":"10.1007/s40200-020-00702-1","url":null,"abstract":"<p><strong>Purpose: </strong>Endocrinology and Metabolism Research Institute (EMRI), Tehran University of Medical Sciences, has achieved many advances in the understanding of epidemiology, pathology, and molecular biology of thyroid cancer (TC). This paper will focus on published literature in the field of TC research at EMRI since its inception.</p><p><strong>Methods: </strong>A comprehensive literature search of \"Scopus\", \"Web of Science (ISI)\", \"PubMed\", and \"SID\" databases was done to identify TC-based studies in EMRI since 2005, using the predefined keywords.</p><p><strong>Results: </strong>All the records were reviewed. Eventually, 46 articles that met the inclusion and exclusion criteria were considered. Timeline, characteristics, and summarized findings of the included most studies have been briefly described.</p><p><strong>Conclusion: </strong>The main focus of the TC research at EMRI is to investigate genetic and epigenetic changes as well as the cellular and molecular aspects seen more frequently in TC patients, and find out how exactly these alterations lead to more aggressive TC behavior and resistance to the conventional treatment approaches in those patients.</p>","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"88 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2021-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11599522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85631556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gita Shafiee, Azadeh Aletaha, Saba Maleki Birjandi, Mohammad Jabbari, Ramin Heshmat, Bagher Larijani
{"title":"Past, present and future trends of sarcopenia research in endocrinology & metabolism research institute:a scientometric study.","authors":"Gita Shafiee, Azadeh Aletaha, Saba Maleki Birjandi, Mohammad Jabbari, Ramin Heshmat, Bagher Larijani","doi":"10.1007/s40200-020-00691-1","DOIUrl":"10.1007/s40200-020-00691-1","url":null,"abstract":"<p><strong>Background: </strong>Sarcopenia is an important disease that needs attention in the world. The aim of this paper was to quantify the trend of sarcopenia's scientific publications of EMRI (Endocrinology & Metabolism Research Institute, Iran).</p><p><strong>Methods: </strong>All studies and scientific articles on sarcopenia which were affiliated to EMRI and its research centers have been recruited in this review through an inclusive search in web of science until 20th December 2019. The number of documents, publication year, main journals, citations, subject area and co-authorship network of authors were assessed.</p><p><strong>Results: </strong>Totally, 28 documents from EMRI were related to sarcopenia and indexed in the web of science. The number of documents showed an increasing trend. Most publications were \"meeting abstract\" at prestigious congresses. The top subject area were \"epidemiology\" and \"association with other diseases\". The highest cited article was a systematic review study, and the top source was \"Diabetes & Metabolic Disorders\" Journal.</p><p><strong>Conclusion: </strong>EMRI provides an appropriate face of sarcopenia publications in the world. However, there is a need for more effort in other subject areas of sarcopenia, this study would be helpful for Iranian researchers to conduct better research in this field.</p>","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"72 11 1","pages":"1801-1807"},"PeriodicalIF":0.0,"publicationDate":"2021-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11599543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90258329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antibody-Mediated Immune Response And COVID-19","authors":"Z. Najafi","doi":"10.24966/dmd-201x/100035","DOIUrl":"https://doi.org/10.24966/dmd-201x/100035","url":null,"abstract":"This work presents a Mini- review of the literature on COVID-19 antibody tests. Severe Acute Respiratory Syndrome of Corona Virus 2 (SARS-CoV-2) and the resulting COVID-19 pandemic are important diagnostic challenges. There are several diagnostic tools available to identify a current infection, rule out an infection, identify people in need of intensive care, or test for a previous infection and immune response.","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81764783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diabetes And Obesity - Inextricable Diseases","authors":"Juliana Simonetti","doi":"10.24966/dmd-201x/100036","DOIUrl":"https://doi.org/10.24966/dmd-201x/100036","url":null,"abstract":"Diabetes and obesity are global epidemics and the prevalence of both has increased in parallel. The relationship between obesity and diabetes is clear as nearly 90% of people with diabetes have obesity. Multiple factors contribute to obesity and include dietary, environmental and iatrogenic causes all of which can affect metabolism directly and independently of caloric intake alone. Studies focused on the pathophysiology of the relationship between diabetes and obesity has led to innovations in diabetes care with a focus on obesity.","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90541177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Antidiabetic and Histopathological Activities of Embelia robusta Seeds Extract against Alloxan-Induced Diabetic Wistar Rats","authors":"Sharada Seekondaa","doi":"10.24966/dmd-201x/100037","DOIUrl":"https://doi.org/10.24966/dmd-201x/100037","url":null,"abstract":"To investigate the anti-diabetic activity of methanolic seed extract of Embelia robusta (E.robusta) on Alloxan (130 mg/kg body weight) induced diabetic rats.","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85369375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Burden of non-communicable diseases in Iran: past, present, and future.","authors":"Arya Aminorroaya, Nima Fattahi, Sina Azadnajafabad, Esmaeil Mohammadi, Kosar Jamshidi, Mahtab Rouhifard Khalilabad, Sahar Mohammadi Fateh, Shohreh Naderimagham, Negar Rezaei, Bagher Larijani, Farshad Farzadfar","doi":"10.1007/s40200-020-00669-z","DOIUrl":"10.1007/s40200-020-00669-z","url":null,"abstract":"<p><p>Iran, as an in-transition country, tackled communicable diseases and now is confronting emerging challenges of non-communicable diseases (NCDs) in the path to reach health for everyone at all ages by 2030. Across Iran, death-averting treatments of NCDs have been expanded recently which might cause a shift toward a greater share of years lived with disability (YLDs) compared to years of life lost (YLLs) in the disability-adjusted life years of NCDs. Since the management of disability differs from the reduction of mortality in terms of public health policies, depicting the current picture of the burden of NCDs is principal for policymakers in achieving health for all. In this communication, we briefly reviewed our current knowledge about the burden of NCDs in Iran and found that burdens of cardiovascular diseases and asthma are shifting toward greater YLDs than YLLs. In addition to expanding preventive measures and maintenance of the current system, this profile calls policymakers for the development of more rehabilitation centers for patients with ischemic heart disease, stroke, and respiratory diseases to mitigate their disabilities. The consistent increase in the age-standardized YLD rate of neoplasms necessitates providing rehabilitation centers as well. Morbidity and mortality of diabetes have increased robustly which warrant extensive preventive and control measures. It should be noted that the estimates of the Global Burden of Disease study offer us invaluable insights on the burden of diseases in Iran; nonetheless, efforts for gathering nationally-representative data, e.g., National and Subnational Burden of Diseases, Injuries, and Risk Factors study, are strongly encouraged in the future.</p>","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"70 1","pages":"1793-1799"},"PeriodicalIF":0.0,"publicationDate":"2020-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11599516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79049000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ozra Tabatabaei-Malazy, Rasha Atlasi, Shirin Hasani-Ranjbar, Mohammad Abdollahi, Marzieh Vahid Dastjerdi, Bagher Larijani
{"title":"Scientometric study of academic publications on herbal medicines in Endocrinology & Metabolism Research Institute (EMRI) of Tehran University of Medical Sciences.","authors":"Ozra Tabatabaei-Malazy, Rasha Atlasi, Shirin Hasani-Ranjbar, Mohammad Abdollahi, Marzieh Vahid Dastjerdi, Bagher Larijani","doi":"10.1007/s40200-020-00622-0","DOIUrl":"10.1007/s40200-020-00622-0","url":null,"abstract":"<p><strong>Background: </strong>After the emphasis of the World Health Organization (WHO) on herbal medicines as the primary source for the care and treatment of some diseases, scientific publications increased in this regard. A significant body of basic and clinical researches in the field of herbal medicines are conducted in Endocrinology and Metabolism Research Institute (EMRI). This scientometric study is investigated to assess the global scientific production of EMRI in field of herbal medicines and endocrine disorders.</p><p><strong>Methods: </strong>Some of our search terms were \"herbal medicine\", \"Chinese medicine\", \"traditional medicine\", \"endocrine\", \"metabolism\", and \"emri\" from Scopus, Web of Science (WOS), and PubMed databases until June 20, 2020. Extracted data including first author, journal name, publication year, type of paper and number of citations were analyzed using analysis tools provided by Scopus, WOS databases, and SPSS version 15.</p><p><strong>Results: </strong>Overall, 126 studies affiliated to EMRI were published on this topic. The number of these publications showed a non-significant increasing time trend. Majority of the published papers were original articles (>60%) and the two top subject areas were medicine and drug. The documents were cited totally 2900, and 2377 times with an average citation/article 29.59, and 24.76 in Scopus and WOS, respectively. The h-index of documents were 28 and 25, in Scopus and WOS, respectively. The highest cited article was a systematic review study in field of diabetes, and top source was \"Daru Journal of Pharmaceutical Sciences\". Top author was affiliated to EMRI, followed by an author from pharmaceutical reserachers as national co-authorship. The highest international co-authorship was with the US.</p><p><strong>Conclusions: </strong>A promising scientific productivity is shown in the studied field. However, the number of publications is insufficient, and more evidence-based publications are required on this topic.</p>","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"21 1","pages":"1783-1791"},"PeriodicalIF":0.0,"publicationDate":"2020-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11599494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84429762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Iranian Multicenter Osteoporosis Studies (IMOS) during last decade: rationale, main findings, lessons learned and the way forward.","authors":"Noushin Fahimfar, Safoora Gharibzadeh, Patricia Khashayar, Reza Rajabian, Gholamhossein Ranjbar Omrani, Amir Bahrami, Iraj Nabipour, Afshin Ostovar, Bagher Larijani","doi":"10.1007/s40200-020-00600-6","DOIUrl":"10.1007/s40200-020-00600-6","url":null,"abstract":"<p><strong>Purpose: </strong>Osteoporosis remains a major public health concern, considering its high prevalence along with its association with osteoporotic fractures. It imposes a heavy burden on the society worldwide as the population ages. This paper aims to provide a brief review on Iranian multicenter osteoporosis studies (IMOS) studies and provide some recommendations for improvement.</p><p><strong>Methods: </strong>IMOS studies were conducted to investigate the prevalence of osteoporosis and related risk factors. This paper provides a general view on the Iranian multicenter osteoporosis studies (IMOS), conducted during last decades.</p><p><strong>Results: </strong>The results showed a high prevalence of osteoporosis and vitamin D deficiency in the Iranian population. Although the study protocols were mainly similar, some differences were observed in terms of the study population and design. The protocol of IMOS-3 was modified to overcome the setbacks noted in the previous studies; however, it was implemented in two cities with noticeably different socioeconomic and geographical characteristics from five cities where the first phase was conducted, resulting in different lifestyles and habits. Although previous IMOS studies have raised major concerns regarding the high prevalence of osteoporosis and vitamin D deficiency, interpretation should be made with caution given the differences, especially in the surveyed cities. Such discrepancies cause problems in trend analysis, and nationally representative samplings are preferably needed to correctly compare the prevalence of osteoporosis and related risk factors.</p><p><strong>Conclusions: </strong>Considering the aging population and the importance of osteoporosis and its complication, developing a standard surveillance system to obtain valid and nationally representative estimates is recommended.</p>","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"20 1","pages":"1449-1454"},"PeriodicalIF":0.0,"publicationDate":"2020-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11599673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87174554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Osteoporosis researches in Endocrinology & Metabolism Research Institute (EMRI) of Tehran University of Medical Sciences; a Scientometrics study.","authors":"Mohammad Javad Mansourzadeh, Kazem Khalagi, Hossein Yarmohammadi, Arash Ghazbani, Noushin Fahimfar, Firoozeh Hajipour, Mahnaz Sanjari, Safoora Gharibzadeh, Neda Mehrdad, Bagher Larijani, Afshin Ostovar","doi":"10.1007/s40200-020-00599-w","DOIUrl":"10.1007/s40200-020-00599-w","url":null,"abstract":"<p><strong>Purpose: </strong>We investigated the research conducted on osteoporosis at EMRI to provide practical implications and suggestions for the development of future research.</p><p><strong>Methods: </strong>We searched osteoporosis and related concepts, as well as various forms of affiliations to EMRI to find published documents indexed in Web of Science, PubMed, and Scopus databases until January 27, 2020. The main purpose and scopes of the studies were classified into seven main study areas. Co-authorship relations were examined using the VOSviewer and keyword analysis was carried out by the ScientoPy.</p><p><strong>Results: </strong>A total 201 papers on the subject of osteoporosis with organizational affiliation to EMRI were found after initial screening and removing duplicates. A time trend analysis of publications showed a growing trend of EMRI's publication in the field of osteoporosis since 2014. A total of 558 independent authors participated in osteoporosis-related research at EMRI, and the average contribution of authors was 6.72 per papers. The Co-authorship network for authors contributing in at least five publications, showed 4 main clusters of independent authors. The co-occurrence network of keywords included three large and intertwined clusters including the epidemiology of osteoporosis and its resulting fractures and risk factors, bone markers and monitoring the effectiveness of treatment with them, and nutrition and supplements in the field of osteoporosis and fractures.</p><p><strong>Conclusion: </strong>EMRI has significantly contributed in osteoporosis science and related subjects during recent years, especially in public health aspects of osteoporosis and its risk factors and consequences. More attention should be paid to other areas such clinical and basic science studies.</p>","PeriodicalId":15604,"journal":{"name":"Journal of Diabetes & Metabolic Disorders","volume":"27 1","pages":"1773-1781"},"PeriodicalIF":0.0,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11599666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83341861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}