Journal of Drugs in Dermatology最新文献

{"title":"Decoding Sensitive Skin Syndrome: International Expert Advisory Insights on Management From India and the United States of America.","authors":"Adam Friedman, Anurag Tiwari, Sushil Tahiliani, Krupa Shankar, Arun Inamdar, Maleeka Sachdev, Kashish Kalra, Geetanjali Shetty, Rajesh Nair, Shraddha M, Debjit Kar, Dyotona Sen, Sanjay Choudhary","doi":"10.36849/JDD.9575","DOIUrl":"10.36849/JDD.9575","url":null,"abstract":"<p><strong>Background: </strong>Sensitive skin syndrome (SSS) is a common self-reported condition, more prevalent in women, characterized by redness, irritation, and discomfort in response to various triggers. SSS remains a multifactorial condition with overlapping symptoms and no clear correlation between sensory complaints and observable signs, complicating both diagnosis and management. This study aimed to establish expert-driven recommendations for the diagnosis, treatment, and holistic care of SSS.</p><p><strong>Methods: </strong>In May 2024, a panel of 11 international dermatologists reviewed literature, answered questionnaires, and convened to integrate clinical experience and emerging evidence into expert recommendations on SSS diagnosis, treatment, and holistic care.</p><p><strong>Results: </strong>Experts determined that SSS is a distinct medical condition requiring systematic evaluation. Recommended diagnostic approaches included patient history, physical examination, validated self-assessment tools such as Sensitive Scale-10, dermoscopy, and sensory reactivity testing to exclude other conditions. Key findings included overlap between SSS and hyperhidrosis, supporting cross-screening, and management strategies recommending low- to medium-potency topical corticosteroids for flares and pimecrolimus as a steroid-free long-term option. Dermocosmetics with panthenol, glycerin, ceramides, hyaluronic acid, and niacinamide were recommended for barrier repair, and the Cleanse, Treat, Moisturize, Protect (CTMP&reg;) regimen was emphasized as a cornerstone of holistic skincare.</p><p><strong>Discussion: </strong>The advisory board highlighted that underdiagnosis and low awareness hinder effective management. Combining pharmacological and dermocosmetic strategies improves outcomes, but education of both clinicians and patients remains a challenge.</p><p><strong>Conclusions: </strong>SSS is a clinically relevant condition requiring structured diagnostics, recognition of comorbidities, and integrated treatment. Greater awareness and education are essential to improve care. &nbsp.</p>","PeriodicalId":15566,"journal":{"name":"Journal of Drugs in Dermatology","volume":"25 7","pages":"632-640"},"PeriodicalIF":2.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148390920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitiligo Successfully Treated With Roflumilast Cream 0.3.","authors":"Maninder Longowal, Sofia O Maruschak-Love","doi":"10.36849/JDD.9990","DOIUrl":"10.36849/JDD.9990","url":null,"abstract":"<p><p>Vitiligo is an autoimmune cutaneous depigmenting disorder that can have significant psychological impacts on affected patients, posing a burden to daily life, which can be even more apparent in patients with deeper Fitzpatrick skin tones. Here we report the case of an adult patient with skin of color treated with roflumilast cream 0.3% following an unsatisfactory response to typical treatments. Treatment resulted in almost full repigmentation on the forehead and cheeks. This case suggests that roflumilast cream 0.3% may have a positive therapeutic effect for patients with vitiligo who are unresponsive to other conventional therapies. &nbsp.</p>","PeriodicalId":15566,"journal":{"name":"Journal of Drugs in Dermatology","volume":"25 7","pages":"662-663"},"PeriodicalIF":2.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148391036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative Analysis of 8 Facial Cleansers Using Corneosurfametry Reveals Differentiated Irritation Potential.","authors":"Sindhu Garimella, Thu Q Nguyen, Christine Emesiani, Matthew Meckfessel","doi":"10.36849/JDD.10028","DOIUrl":"https://doi.org/10.36849/JDD.10028","url":null,"abstract":"<p><strong>Background: </strong>Facial cleansers can disrupt the stratum corneum and cause irritation. Selecting a cleanser that is both effective and gentle is foundational to a tailored skincare routine, particularly for individuals with sensitive skin. This project assessed the relative mildness of Cetaphil&reg; Gentle Skin Cleanser (GSC; Galderma Laboratories, LP, Fort Worth, TX) vs 7 other commercially available gentle cleansers using corneosurfametry.</p><p><strong>Methods: </strong>Surface skin cells were collected from the volar forearms of 18 volunteer participants using D‑Squame&reg; standard sampling discs. Discs were then incubated for 10 minutes in a 10% aqueous solution of one of the 8 cleansers, 5% sodium lauryl sulfate (positive control), or water (negative control). Samples were stained with toluidine blue&ndash;basic fuchsin and measured by chromameter. Colorimetric index of mildness (CIM) least-squares means were compared pairwise versus GSC, and photographs provided qualitative corroboration. A higher CIM indicated a milder cleanser, while a lower CIM indicated a harsher cleanser.</p><p><strong>Results: </strong>The mean CIM for GSC was 63.87; pairwise comparisons indicated statistically significant differences between GSC and the mean CIM of the 7 comparators, which ranged from 46.95 to 53.32. Photographic tape appearance was concordant with CIM rankings.</p><p><strong>Conclusion: </strong>GSC was significantly milder than the comparator cleansers as assessed by CIM and photographic analysis of the tape strips. These data suggest that there are differences in irritation potential among commercially available facial cleansers, which may help ensure patients and providers select a sufficiently mild cleanser for those with sensitive skin.</p>","PeriodicalId":15566,"journal":{"name":"Journal of Drugs in Dermatology","volume":"25 7","pages":"655-658"},"PeriodicalIF":2.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148390891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ChatGPT Exhibits Reduced Sensitivity in Identifying Concern for Malignancy in Darker Skin Tones.","authors":"Nicholas Schell, Simona A Alomary, Nicole Baker, Jina Chung, Temitayo Ogunleye, Susan C Taylor","doi":"10.36849/JDD.10083","DOIUrl":"https://doi.org/10.36849/JDD.10083","url":null,"abstract":"","PeriodicalId":15566,"journal":{"name":"Journal of Drugs in Dermatology","volume":"25 7","pages":"e64-e65"},"PeriodicalIF":2.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148390931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Update on Common Genodermatoses Not to be Missed.","authors":"Mina Farah, Nikkia Zarabian, Robin Picavia, Anna Yasmine Kirkorian, Adam Friedman","doi":"10.36849/JDD.0726","DOIUrl":"https://doi.org/10.36849/JDD.0726","url":null,"abstract":"","PeriodicalId":15566,"journal":{"name":"Journal of Drugs in Dermatology","volume":"25 7","pages":"673-674"},"PeriodicalIF":2.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148390927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Dermatology Procedure Perceptions and Seeking in LGBTQ+ Patients.","authors":"Vincent Pecora, Sara Abdel Azim, Cleo Whiting, Sahar Heidari, Joung Min Choi, Erika McCormick, Liqing Zhang, Angelo Landriscina, Pooja Sodha, Adam Friedman","doi":"10.36849/JDD.9200","DOIUrl":"https://doi.org/10.36849/JDD.9200","url":null,"abstract":"","PeriodicalId":15566,"journal":{"name":"Journal of Drugs in Dermatology","volume":"25 7","pages":"e59-e60"},"PeriodicalIF":2.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148390995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Skin of Color Representation Among Common Search Engine Images.","authors":"Robert Adler, Kateryna Karpoff, Manan Mehta, Emily Cowen, Katerina Svigos, Justin Wu Marson, Jessica Lori Feig","doi":"10.36849/JDD.9527","DOIUrl":"https://doi.org/10.36849/JDD.9527","url":null,"abstract":"","PeriodicalId":15566,"journal":{"name":"Journal of Drugs in Dermatology","volume":"25 7","pages":"670-671"},"PeriodicalIF":2.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148391006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Racial Differences in Secondary Skin Complications and Timing of Topical Therapy Initiation for Pseudofolliculitis Barbae: A Multicenter Retrospective Database Cohort Study.","authors":"Simona A Alomary, Nicole J Baker, Andrew Z Li, Temitayo Ogunleye, Susan C Taylor","doi":"10.36849/JDD.9835","DOIUrl":"https://doi.org/10.36849/JDD.9835","url":null,"abstract":"","PeriodicalId":15566,"journal":{"name":"Journal of Drugs in Dermatology","volume":"25 7","pages":"e69-e70"},"PeriodicalIF":2.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148390932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hidden Harms of Hair Relaxers: A Call to Action.","authors":"Rebecca Fliorent, Lisa Huang, Jiwoo Kim, Victoria Youssef, Anna Terzain, Mark Hanna, Marium Rashid, Mohammad Fardos, Richard Miller","doi":"10.36849/JDD.9419","DOIUrl":"https://doi.org/10.36849/JDD.9419","url":null,"abstract":"","PeriodicalId":15566,"journal":{"name":"Journal of Drugs in Dermatology","volume":"25 7","pages":"672"},"PeriodicalIF":2.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148390979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Public Interest in Hyperpigmentation: Insights From a Google Trends Analysis.","authors":"Grace Ugwueke, Nada Elbuluk","doi":"10.36849/JDD.10055","DOIUrl":"https://doi.org/10.36849/JDD.10055","url":null,"abstract":"<p><strong>Background: </strong>Pigmentary disorders, particularly hyperpigmentation, disproportionately affect individuals with skin of color and are associated with significant psychosocial burden. Despite their global prevalence, real-time data on public awareness and interest remain limited. Digital tools such as Google Trends offer a novel approach to assessing public interest in dermatologic conditions.</p><p><strong>Methods: </strong>Google Trends was used to evaluate public interest in hyperpigmentation-related terms such as \"hyperpigmentation\", \"pigmentation\", \"skin brightening\", \"brown spots\", and \"dark spot treatment\" from January 2004 to October 2025. Data were analyzed for the United States (US) and globally using relative search volume (RSV), a normalized scale from 0-100 representing peak popularity within a defined region and time frame. Temporal trends, seasonal variation, and geographical distribution were assessed.</p><p><strong>Results: </strong>Across all terms, RSV demonstrated a sustained increase over time both domestically and globally. \"Pigmentation\" and \"hyperpigmentation\" consistently showed the highest search interest, with a marked spike in \"hyperpigmentation\" in early 2025. \"Brown spots\" exhibited seasonal peaks during the summer months. In the US, the highest relative search interest for \"brown spots\" was observed in southern states, including South Carolina, Alabama, and Tennessee. Globally, countries such as Ghana, Nigeria, and Mauritius frequently ranked highly across multiple terms.</p><p><strong>Conclusion: </strong>Public interest in pigmentary disorders has increased significantly over the past two decades. Google Trends provides valuable insight into consumer awareness and information-seeking behavior, highlighting potential gaps in education and access to dermatologic care. These findings may inform targeted public health initiatives and culturally responsive interventions for populations disproportionately affected by pigmentary conditions. &nbsp.</p>","PeriodicalId":15566,"journal":{"name":"Journal of Drugs in Dermatology","volume":"25 7","pages":"629-631"},"PeriodicalIF":2.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148391000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}