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Blood Pressure Lowering May Decrease Cognitive Decline; But Are We Ready to Lower Blood Pressure in the Real World? 降低血压可减少认知能力下降;但是我们准备好在现实世界中降低血压了吗?
Journal of Clinical Cardiology Pub Date : 2021-01-01 DOI: 10.33696/cardiology.2.014
Madhuri Ramakrishnan, Gary Gronseth, Aditi Gupta
{"title":"Blood Pressure Lowering May Decrease Cognitive Decline; But Are We Ready to Lower Blood Pressure in the Real World?","authors":"Madhuri Ramakrishnan, Gary Gronseth, Aditi Gupta","doi":"10.33696/cardiology.2.014","DOIUrl":"https://doi.org/10.33696/cardiology.2.014","url":null,"abstract":"Dementia and hypertension are highly prevalent, epidemiologically related chronic conditions disproportionately affecting older persons; approximately 97% of persons with dementia [1] and 66% with hypertension are over the age of 65 [2]. With increasing life expectancy, the prevalence of both dementia and hypertension is projected to increase further. Both conditions increase morbidity and mortality, and are among the largest contributors to healthcare expenditure – the total estimated expenditure on dementia in the United States in 2020 was $ 305 billion [3], and the annual expenditure on hypertension is estimated to be around $ 131 billion [4]. In addition, hypertension is an independent modifiable risk factor for dementia [5,6]. More recently, we analyzed data from randomized controlled trials (RCTs) to show that lowering blood pressure (BP) may slow decline in cognition [7]. Unfortunately, BP control has declined in the recent years, from 54% in 2013 to 44% in 2017 [8]. Here we will discuss some current logistical issues with hypertension management in older patients and future directions.","PeriodicalId":15510,"journal":{"name":"Journal of Clinical Cardiology","volume":"2 2","pages":"34-38"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40580249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentary on: Peptidylglycine α-amidating Monooxygenase is Required for Atrial Secretory Granule Formation. 评论:肽基甘氨酸α-酰胺化单加氧酶是心房分泌颗粒形成所必需的。
Journal of Clinical Cardiology Pub Date : 2021-01-01 DOI: 10.33696/cardiology.2.022
Emil Daniel Bartels, Jens Peter Gøtze, Richard E Mains, Betty A Eipper
{"title":"Commentary on: Peptidylglycine α-amidating Monooxygenase is Required for Atrial Secretory Granule Formation.","authors":"Emil Daniel Bartels,&nbsp;Jens Peter Gøtze,&nbsp;Richard E Mains,&nbsp;Betty A Eipper","doi":"10.33696/cardiology.2.022","DOIUrl":"https://doi.org/10.33696/cardiology.2.022","url":null,"abstract":"<p><p>The electron-dense spherical granules found in the perinuclear region of atrial myocytes store and release both proatrial and probrain natriuretic peptides (proANP and proBNP, respectively). Mature ANP and BNP produce vasodilation and natriuresis and inhibit the renin-angiotensin and sympathetic nervous systems. Although neither ANP nor BNP is a-amidated, Peptidylglycine a-Amidating Monooxygenase (PAM), an integral membrane enzyme known to catalyze the a-amidation of peptidylglycine precursors, is the major atrial granule membrane protein. Selective deletion of PAM from cardiomyocytes impairs their ability to store proANP, resulting in an increase in proANP secretion. Exogenous expression of active or inactive PAM protein restores the ability of atrial myocytes to store proANP, leading to the suggestion that PAM functions as a cargo receptor for newly synthesized proANP.</p>","PeriodicalId":15510,"journal":{"name":"Journal of Clinical Cardiology","volume":"2 4","pages":"75-80"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39573863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Cardiovascular Diseases in Acromegaly: Not Diagnosed What is Not Suspected 肢端肥大症的心血管疾病:未诊断，未怀疑
Journal of Clinical Cardiology Pub Date : 2020-12-31 DOI: 10.23937/2378-2951/1410207
Martinez Ivan Lozada, Llinás Daniela Torres, Nieves Andres Llamas
{"title":"Cardiovascular Diseases in Acromegaly: Not Diagnosed What is Not Suspected","authors":"Martinez Ivan Lozada, Llinás Daniela Torres, Nieves Andres Llamas","doi":"10.23937/2378-2951/1410207","DOIUrl":"https://doi.org/10.23937/2378-2951/1410207","url":null,"abstract":"Citation: Martinez IL, Llinás DT, Nieves AL (2020) Cardiovascular Diseases in Acromegaly: Not Diagnosed What is Not Suspected. Int J Clin Cardiol 7:207. doi.org/10.23937/2378-2951/1410207 Accepted: December 10, 2020: Published: December 12, 2020 Copyright: © 2020 Martinez IL, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.","PeriodicalId":15510,"journal":{"name":"Journal of Clinical Cardiology","volume":"115 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74759647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypertrabeculation with Infiltrative Features across Multiple Imaging Modalities - A Remnant of Prior Cardiac Sarcoid or Primary Noncompaction Cardiomyopathy 具有浸润性特征的小梁亢进在多种成像方式-先前心脏肉瘤或原发性非压实性心肌病的残余
Journal of Clinical Cardiology Pub Date : 2020-11-28 DOI: 10.23937/2378-2951/1410204
B. Liam, M. Joseph, W. David
{"title":"Hypertrabeculation with Infiltrative Features across Multiple Imaging Modalities - A Remnant of Prior Cardiac Sarcoid or Primary Noncompaction Cardiomyopathy","authors":"B. Liam, M. Joseph, W. David","doi":"10.23937/2378-2951/1410204","DOIUrl":"https://doi.org/10.23937/2378-2951/1410204","url":null,"abstract":"Citation: Back L, Magdy J, Wong D (2020) Hypertrabeculation with Infiltrative Features across Multiple Imaging Modalities A Remnant of Prior Cardiac Sarcoid or Primary Noncompaction Cardiomyopathy. Int J Clin Cardiol 7:204. doi.org/10.23937/2378-2951/1410204 Accepted: November 26, 2020: Published: November 28, 2020 Copyright: © 2020 Back L, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.","PeriodicalId":15510,"journal":{"name":"Journal of Clinical Cardiology","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78663491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unexpected Coronary Angiographic Findings in a Patient with Wellens' Sign 1例韦伦斯征患者冠状动脉造影的意外发现
Journal of Clinical Cardiology Pub Date : 2020-10-23 DOI: 10.23937/2378-2951/1410203
M. KimMorris, S. TaylorJonathan, S. AndersonJenna, G. ZarragaIgnatius
{"title":"Unexpected Coronary Angiographic Findings in a Patient with Wellens' Sign","authors":"M. KimMorris, S. TaylorJonathan, S. AndersonJenna, G. ZarragaIgnatius","doi":"10.23937/2378-2951/1410203","DOIUrl":"https://doi.org/10.23937/2378-2951/1410203","url":null,"abstract":"Citation: Kim MM, Taylor JS, Anderson JS, Zarraga IG (2020) Unexpected Coronary Angiographic Findings in a Patient with Wellens’ Sign. Int J Clin Cardiol 7:203. doi.org/10.23937/2378-2951/1410203 Accepted: October 21, 2020: Published: October 23, 2020 Copyright: © 2020 Kim MM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.","PeriodicalId":15510,"journal":{"name":"Journal of Clinical Cardiology","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85881638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Acute Success and Long-term Follow-up of Catheter Ablation of Isthmus-dependent Atrial Flutter; A Comparison of 10 mm Tip Standard, 6 mm Tip Irrigated Radiofrequency, and Cryotherapy Catheters 导管消融治疗峡部依赖性心房扑动的急性成功及长期随访10mm尖端标准导管、6mm尖端射频灌洗导管和冷冻治疗导管的比较
Journal of Clinical Cardiology Pub Date : 2020-10-15 DOI: 10.33696/cardiology.1.004
K. Okishige, Mitsumi Yamashita, Tomofumi Nakamura, Y. Yamauchi, K. Hirao, T. Sasano
{"title":"Acute Success and Long-term Follow-up of Catheter Ablation of Isthmus-dependent Atrial Flutter; A Comparison of 10 mm Tip Standard, 6 mm Tip Irrigated Radiofrequency, and Cryotherapy Catheters","authors":"K. Okishige, Mitsumi Yamashita, Tomofumi Nakamura, Y. Yamauchi, K. Hirao, T. Sasano","doi":"10.33696/cardiology.1.004","DOIUrl":"https://doi.org/10.33696/cardiology.1.004","url":null,"abstract":"Various catheter ablation technologies have evolved to improve the procedural success and safety of cavotricuspid isthmus (CTI) block. Numerous studies have compared the different energy types, catheter tip sizes, and energy settings [1-3]. Irrigated or large-tip catheters have a theoretical advantage of creating wider and deeper lesions than the conventional catheters [4,5]. Disadvantageous aspects of radiofrequency (RF) energy include pain, overheating with popping, char formation, and a risk to the coronary arteries [6]. Cryoablation (CRYO) is a relatively recent addition to the transvenous ablation armamentarium and has been shown to be comparable to RF. The development of 10 mm tip RF (10RF), 4.0 mm open-irrigated-tip RF (IRRF), and 8 mm tip cryothermy ablation catheter has increased the interest in this technology for atrial flutter (AFL) ablation. There have been no randomized comparative studies published comparing CRYO, 10RF and IRRF. Abstract","PeriodicalId":15510,"journal":{"name":"Journal of Clinical Cardiology","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75453445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipoprotein Apheresis: First FDA Indicated Treatment for Elevated Lipoprotein(a) 脂蛋白分离:首个FDA批准的治疗脂蛋白升高的方法(a)
Journal of Clinical Cardiology Pub Date : 2020-10-15 DOI: 10.33696/cardiology.1.002
Anne K. Nugent, Jessica V. Gray, L. Gorby, P. Moriarty
{"title":"Lipoprotein Apheresis: First FDA Indicated Treatment for Elevated Lipoprotein(a)","authors":"Anne K. Nugent, Jessica V. Gray, L. Gorby, P. Moriarty","doi":"10.33696/cardiology.1.002","DOIUrl":"https://doi.org/10.33696/cardiology.1.002","url":null,"abstract":"Lipoprotein(a) [Lp(a)] is a genetically determined lowdensity lipoprotein (LDL) particle that is comprised of apolipoprotein(a) [apo(a)] and apolipoprotein B-100 (apoB) moieties. It is well-established that elevated Lp(a) is an independent risk factor for cardiovascular disease (CVD). It is associated with an increased risk of myocardial infarction, aortic valve stenosis, ischemic stroke and peripheral vascular disease [1,2].","PeriodicalId":15510,"journal":{"name":"Journal of Clinical Cardiology","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79088821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Enterobacter Related İmplantable Cardiac Defibrillator Lead Endocarditis in Dialysis Patient 肠杆菌相关İmplantable透析患者心脏除颤器导联心内膜炎
Journal of Clinical Cardiology Pub Date : 2020-09-16 DOI: 10.23937/2378-2951/1410201
Duman Hakan, Bodur Oğuzhan, C. Yüksel
{"title":"Enterobacter Related İmplantable Cardiac Defibrillator Lead Endocarditis in Dialysis Patient","authors":"Duman Hakan, Bodur Oğuzhan, C. Yüksel","doi":"10.23937/2378-2951/1410201","DOIUrl":"https://doi.org/10.23937/2378-2951/1410201","url":null,"abstract":"Use of intracardiac devices for heart diseases is increasing Worldwide. One of the important complications of pacemakers is infective endocarditis from the leads as the source. In this case, we report a 61-years-old male patient who is on dialysis and presented with implantable cardioverter defibrillator (ICD) lead endocarditis caused by Enterobacter Cloacae four months following implantation. Learning objective: Intracardiac devices are one of the predisposing conditions for infective endocarditis. It is known that the immune system is weak in patients with chronic renal failure. Patients with dialysis should be careful for endocarditis following intracardiac pace implantation.","PeriodicalId":15510,"journal":{"name":"Journal of Clinical Cardiology","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88635417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multi-Modality Imaging of a Case of Multiple Intra-Cardiac Aneurysms Complicated by Mitral Valve Leaflet Perforation 多发性心内动脉瘤合并二尖瓣小叶穿孔1例多模态成像分析
Journal of Clinical Cardiology Pub Date : 2020-09-03 DOI: 10.23937/2378-2951/1410199
Meel Ruchika, L. Liam, G. Ricardo, Ngutshane Bongane, Mogaladi Shungu
{"title":"Multi-Modality Imaging of a Case of Multiple Intra-Cardiac Aneurysms Complicated by Mitral Valve Leaflet Perforation","authors":"Meel Ruchika, L. Liam, G. Ricardo, Ngutshane Bongane, Mogaladi Shungu","doi":"10.23937/2378-2951/1410199","DOIUrl":"https://doi.org/10.23937/2378-2951/1410199","url":null,"abstract":"• Page 1 of 7 • Meel et al. Int J Clin Cardiol 2020, 7:199 Citation: Meel R, Lorentz L, Goncalves R, Ngutshane B, Mogaladi S (2020) Multi-Modality Imaging of a Case of Multiple Intra-Cardiac Aneurysms Complicated by Mitral Valve Leaflet Perforation. Int J Clin Cardiol 7:199. doi.org/10.23937/2378-2951/1410199 Accepted: September 01, 2020; Published: September 03, 2020 Copyright: © 2020 Meel R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Multi-Modality Imaging of a Case of Multiple Intra-Cardiac Aneurysms Complicated by Mitral Valve Leaflet Perforation","PeriodicalId":15510,"journal":{"name":"Journal of Clinical Cardiology","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91162556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary Percutaneous Coronary Intervention (pPCI) Using Right Fossa Radialis (Dorsal Transradia) Approach 经皮冠状动脉介入治疗(pPCI)采用右桡骨窝(背侧经桡骨)入路
Journal of Clinical Cardiology Pub Date : 2020-08-31 DOI: 10.23937/2378-2951/1410198
Sinha Santosh Kumar, Aggarwal Puneet, P. Umeshwar
{"title":"Primary Percutaneous Coronary Intervention (pPCI) Using Right Fossa Radialis (Dorsal Transradia) Approach","authors":"Sinha Santosh Kumar, Aggarwal Puneet, P. Umeshwar","doi":"10.23937/2378-2951/1410198","DOIUrl":"https://doi.org/10.23937/2378-2951/1410198","url":null,"abstract":"Haematoma, dissection, local site granuloma, and persistent radial artery occlusion are few of the complications of conventional transradial access. The distal radial artery located in the “fossa radialis or anatomical snuffbox” on the dor¬sal side of the hand may be an attractive alternative to conventional radial stick. Here, we report a case of a 47-year-old diabetic male who presented with retrosternal chest pain and sweating of 2-hours duration, and diagnosed as acute inferior wall myocardial infarction. Primary percutaneous coronary intervention of culprit right coronary artery was performed through right transradial approach using fossa radialis (dorsal Transradial).","PeriodicalId":15510,"journal":{"name":"Journal of Clinical Cardiology","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81029950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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