Journal of critical care最新文献

{"title":"Conservative versus liberal fluid resuscitation for septic patients at risk for fluid overload: A systematic review with meta-analysis","authors":"Aadil Bharwani ,&nbsp;Joanna C. Dionne ,&nbsp;María L. Pérez ,&nbsp;Marina Englesakis ,&nbsp;Tine Sylvest Meyhoff ,&nbsp;Praleene Sivapalan ,&nbsp;Fernando G. Zampieri ,&nbsp;M. Elizabeth Wilcox","doi":"10.1016/j.jcrc.2025.155045","DOIUrl":"10.1016/j.jcrc.2025.155045","url":null,"abstract":"<div><h3>Background</h3><div>Intravenous fluid resuscitation forms a crucial part of the sepsis bundle. However, the perception is that patients with comorbidities such as congestive heart failure, chronic kidney disease, and cirrhosis receive lower volumes due to concerns regarding potential for fluid overload. We review outcomes relating to resuscitation with conservative versus liberal volumes in specific patient populations.</div></div><div><h3>Methods</h3><div>We searched MEDLINE, Embase+Embase Classic, Cochrane library, Web of Science, CINAHL Complete, and <span><span>ClinicalTrials.gov</span><svg><path></path></svg></span> for studies that compared outcomes related to different volumes of resuscitation in adult patients with sepsis, along with congestive heart failure, chronic kidney disease, cirrhosis. The primary outcome was all-cause mortality up to 30 days post-discharge. Secondary outcomes included length of stay, intubation rates and duration, and use of vasopressors.</div></div><div><h3>Results</h3><div>A total of 37 observational studies were included. We found no statistically significant difference in all-cause mortality (Odds Ratio [OR] 1.01; 95 % Confidence Interval [CI] 0.86–1.19), rates of ICU admission (Risk Ratio [RR] 0.89; 95 % CI 0.70–1.11), hospital length of stay (Mean Difference [MD] -0.01; 95 % -0.18-0.15), ICU length of stay (MD -0.06; 95 % CI -0.30-0.18), intubation rates (OR 1.00; 95 % 0.76–1.32), duration of mechanical ventilation (MD 0.01; 95 % CI -0.31-0.32) or use of vasopressors (RR 0.81; 95 % CI 0.64–1.02).</div></div><div><h3>Conclusions</h3><div>Among patients with comorbid conditions presenting with sepsis, we found no differences in outcomes related to the volume of fluid administered. Further evidence is needed to guide decisions regarding volume of fluid to administer in these patient populations given the lack of high certainty evidence.</div></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"87 ","pages":"Article 155045"},"PeriodicalIF":3.2,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143512143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Data-driven modeling of inflammation in a canine model of volumetric muscle loss injury suggests distinct type 17 immune responses in response to hydrogel extracellular matrix alone or in combination with topical electrical stimulation","authors":"Ruben Zamora ,&nbsp;Jinling Yin ,&nbsp;Fayten El-Dehaibi ,&nbsp;Derek A. Barclay ,&nbsp;Scott A. Johnson ,&nbsp;Gary An ,&nbsp;Stephen F. Badylak ,&nbsp;Yoram Vodovotz","doi":"10.1016/j.jcrc.2024.154962","DOIUrl":"10.1016/j.jcrc.2024.154962","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"86 ","pages":"Article 154962"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143509028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early dynamic prediction of organ system deterioration in intensive care unit (ICU) patients using machine learning","authors":"Nidhi Soley ,&nbsp;Siqi Zhang ,&nbsp;Jiashan Zong ,&nbsp;Joseph Greenstein ,&nbsp;Casey Overby Taylor ,&nbsp;Timothy Ruchti ,&nbsp;Pedro Alejandro Mendez-Tellez","doi":"10.1016/j.jcrc.2024.154954","DOIUrl":"10.1016/j.jcrc.2024.154954","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"86 ","pages":"Article 154954"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143509418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Network analysis of single-nucleotide polymorphisms (SNPs) associated with aberrant inflammation in trauma patients suggests a role for programs involving CD55 and delineates novel SNPs associated with a Type 17 immune phenotype","authors":"Fayten El-Dehaibi ,&nbsp;Ruben Zamora ,&nbsp;Jinling Yin ,&nbsp;Timthy R. Billiar ,&nbsp;Yoram Vodovotz","doi":"10.1016/j.jcrc.2024.154963","DOIUrl":"10.1016/j.jcrc.2024.154963","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"86 ","pages":"Article 154963"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143509525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative modeling for personalized tranexamic acid dosing in trauma care","authors":"Guanyun Liu ,&nbsp;Amanda E. Shick ,&nbsp;Caroline M. Cook ,&nbsp;Valeria Urrego-Hernandez ,&nbsp;Maya Shamash ,&nbsp;Pranav Kulkarni ,&nbsp;Mitchell J. Cohen ,&nbsp;Amor A. Menezes","doi":"10.1016/j.jcrc.2024.154967","DOIUrl":"10.1016/j.jcrc.2024.154967","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"86 ","pages":"Article 154967"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143509031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Limitations of remarkable human brains demand decision-support","authors":"Alan Morris ,&nbsp;Christopher Horvat ,&nbsp;R. Scott Evans ,&nbsp;Stephen Rees","doi":"10.1016/j.jcrc.2024.154969","DOIUrl":"10.1016/j.jcrc.2024.154969","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"86 ","pages":"Article 154969"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical experimental method compliance quantification challenges","authors":"Alan Morris ,&nbsp;Kang Hoe Lee ,&nbsp;Christopher Horvat ,&nbsp;R. Scott Evans ,&nbsp;Stephen Rees","doi":"10.1016/j.jcrc.2024.154968","DOIUrl":"10.1016/j.jcrc.2024.154968","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"86 ","pages":"Article 154968"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143509032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamic prediction of major adverse kidney events in sepsis-associated acute kidney injury using deep learning","authors":"Kullaya Takkavatakarn ,&nbsp;Wonsuk Oh ,&nbsp;Hernando Gomez ,&nbsp;Umesh Gidwani ,&nbsp;John Oropello ,&nbsp;Roopa Kohli-Seth ,&nbsp;John Kellum ,&nbsp;Girish Nadkarni ,&nbsp;Ankit Sakhuja","doi":"10.1016/j.jcrc.2024.154971","DOIUrl":"10.1016/j.jcrc.2024.154971","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"86 ","pages":"Article 154971"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modeling organ crosstalk and cellular adaptation in response to clinical intervention during multiple organ dysfunction syndrome","authors":"Stefanos Papadopoulos,&nbsp;Robert S. Parker,&nbsp;Gilles Clermont","doi":"10.1016/j.jcrc.2024.154965","DOIUrl":"10.1016/j.jcrc.2024.154965","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"86 ","pages":"Article 154965"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143509029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wave power analysis to assess cardiovascular alterations in sepsis","authors":"Marta Carrara ,&nbsp;Diletta Guberti ,&nbsp;Riccardo Asnaghi ,&nbsp;Manuela Ferrario","doi":"10.1016/j.jcrc.2024.154956","DOIUrl":"10.1016/j.jcrc.2024.154956","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"86 ","pages":"Article 154956"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}