{"title":"Letter to the editor: “Early energy delivery and 28-day mortality in critically ill patients with sepsis: Post hoc analysis of a multicenter cluster-randomised controlled trial”","authors":"Jinghuan Ye , Jinzhen Huang","doi":"10.1016/j.jcrc.2025.155285","DOIUrl":"10.1016/j.jcrc.2025.155285","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"91 ","pages":"Article 155285"},"PeriodicalIF":2.9,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nina Leggett , Yasmine Ali Abdelhamid , Nathan Eric Daniel , Christian Davey , Adam M. Deane , Rebekah Lim , Samuel Ricciardone , Mark Merolli , Kimberley J. Haines
{"title":"Digital health literacy of ICU survivors: A prospective cohort study","authors":"Nina Leggett , Yasmine Ali Abdelhamid , Nathan Eric Daniel , Christian Davey , Adam M. Deane , Rebekah Lim , Samuel Ricciardone , Mark Merolli , Kimberley J. Haines","doi":"10.1016/j.jcrc.2025.155277","DOIUrl":"10.1016/j.jcrc.2025.155277","url":null,"abstract":"<div><h3>Introduction</h3><div>Digital recovery programs for Intensive Care Unit (ICU) survivors have demonstrated feasibility, compared to hospital-based face-to-face delivery. However, limited data exist regarding which survivors can participate and if barriers to uptake exist in some survivor groups. This study aimed to evaluate the digital health literacy of ICU survivors, including their access to use digital health technologies.</div></div><div><h3>Methods</h3><div>A multi-site prospective observational cohort study was conducted. Adult ICU patients admitted for more than 48 h were recruited 4-weeks post-discharge. Participants were consecutively sampled across additional characteristics of interest: older adults (over 65 years of age), rural-residing, and culturally and linguistically diverse (CALD). Eligible patients were contacted via phone, and invited to participate in a single survey, using interpreters as required. The primary outcome measure was the Digital Health Readiness Questionnaire (DHRQ) general score, where greater scores indicate higher literacy. Secondary outcome measures included digital technology access (via the DHRQ digital usage score).</div></div><div><h3>Results</h3><div>60 participants were enrolled, including 23 characterised as older adults, 21 rural-residing and 13 CALD. The median (Q1-Q3) DHRQ general score for the cohort was 56 (43–63), with highest scores in the rural-residing characteristic survivors (60 (53–65)) compared to the older adult (45 (26–54)) and CALD (41 (25–48)). The median DHRQ digital usage domain score was 15 (12–16), with highest scores for the rural-residing characteristic survivors, compared to the older adult and CALD (12 (9–15)).</div></div><div><h3>Conclusions</h3><div>Digital health literacy scores were moderate for all ICU survivor participants, with higher scores reported in survivors with the rural-residing characteristic.</div></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"91 ","pages":"Article 155277"},"PeriodicalIF":2.9,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor: “Observational study of cefepime therapeutic drug monitoring in continuous venovenous hemodialysis”","authors":"Yuqing You , Jinyan Guo , Weifeng Yao","doi":"10.1016/j.jcrc.2025.155290","DOIUrl":"10.1016/j.jcrc.2025.155290","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"91 ","pages":"Article 155290"},"PeriodicalIF":2.9,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the editor: “Diaphragmatic ultrasound for extubation readiness: The role of thickening fraction”","authors":"Jianing Song, Song Peng","doi":"10.1016/j.jcrc.2025.155288","DOIUrl":"10.1016/j.jcrc.2025.155288","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"91 ","pages":"Article 155288"},"PeriodicalIF":2.9,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145219994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor: “An increase in skin blood flow after red blood cell transfusion is associated with an improvement in organ function in critically ill patients”","authors":"Shuai Fang, Meiyu Yang, Yuesong Shen, Wangying Jiang, Tiantian Zhang","doi":"10.1016/j.jcrc.2025.155282","DOIUrl":"10.1016/j.jcrc.2025.155282","url":null,"abstract":"<div><div>This letter praises a study for linking post-transfusion skin blood flow to organ function but identifies three critical weaknesses: the failure to separate the effects of volume expansion from increased oxygen capacity, a weak causal claim due to a long time gap between measurements, and a heterogeneous patient population. It concludes by calling for more rigorous future trials to validate these findings and advance toward a perfusion-guided transfusion strategy.</div></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"91 ","pages":"Article 155282"},"PeriodicalIF":2.9,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145219919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elaine Cavalcante dos Santos, Fabio Silvio Taccone
{"title":"Authors' reply: “An increase in skin blood flow after red blood cell transfusion is associated with an improvement in organ function in critically ill patients”","authors":"Elaine Cavalcante dos Santos, Fabio Silvio Taccone","doi":"10.1016/j.jcrc.2025.155283","DOIUrl":"10.1016/j.jcrc.2025.155283","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"91 ","pages":"Article 155283"},"PeriodicalIF":2.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Authors reply: “Diaphragmatic ultrasound for extubation readiness: The role of thickening fraction”","authors":"Wan Cley Rabuske , Antuani Rafael Baptistella","doi":"10.1016/j.jcrc.2025.155289","DOIUrl":"10.1016/j.jcrc.2025.155289","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"91 ","pages":"Article 155289"},"PeriodicalIF":2.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernando da Silveira , Luiz Henrique de Oliveira , Wagner Nedel , Thiago Costa Lisboa
{"title":"Effectiveness of prophylactic push-dose vasopressors for preventing arterial hypotension during elective orotracheal intubation: A systematic review and meta-analysis","authors":"Fernando da Silveira , Luiz Henrique de Oliveira , Wagner Nedel , Thiago Costa Lisboa","doi":"10.1016/j.jcrc.2025.155275","DOIUrl":"10.1016/j.jcrc.2025.155275","url":null,"abstract":"<div><h3>Background</h3><div>Orotracheal intubation is frequently associated with arterial hypotension, particularly during induction with agents such as propofol. The use of prophylactic push-dose vasopressors (<em>Push-Dose Pressor - PDP</em>) has been proposed to mitigate this drop in blood pressure. However, the effectiveness of PDPs remains uncertain.</div></div><div><h3>Methods</h3><div>We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) assessing the use of PDPs (epinephrine, ephedrine, phenylephrine, or metaraminol) during sedation for tracheal intubation in adult normotensive patients. Searches were performed in MEDLINE, Embase, and Cochrane Library from inception to September 2024. The primary outcome was the difference in mean arterial pressure (MAP) and systolic blood pressure (SBP) before and after intubation between patients who received PDPs and those who did not. Data were synthesized using an inverse variance method, with heterogeneity assessed using Cochran's Q and I<sup>2</sup>.</div></div><div><h3>Results</h3><div>Twenty-four RCTs involving 1915 patients were included. Most trials were conducted in operating rooms among ASA I–II patients undergoing elective procedures. PDP administration resulted in higher MAP (mean difference: 7.6 mmHg; 95 % CI: 4.3–10.8; I<sup>2</sup> = 82 %) and SBP (mean difference: 12.5 mmHg; 95 % CI: 6.4–18.5; I<sup>2</sup> = 92 %) compared with controls. Sensitivity analyses excluding phenylephrine or stratifying ephedrine doses yielded consistent findings. Overall certainty of evidence was low due to heterogeneity and indirectness.</div></div><div><h3>Conclusions</h3><div>Prophylactic push-dose vasopressors modestly increase arterial pressure during tracheal intubation in elective surgical patients. Given the low certainty of evidence and limited generalizability, routine use cannot be currently recommended.</div></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"91 ","pages":"Article 155275"},"PeriodicalIF":2.9,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}