Journal of critical care最新文献

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Authors reply: “An economic model for different anticoagulation strategies in continuous renal replacement therapy” 作者回复:“持续肾替代治疗中不同抗凝策略的经济模型”。
IF 2.9 3区 医学
Journal of critical care Pub Date : 2025-10-14 DOI: 10.1016/j.jcrc.2025.155293
Olivier Ethgen , Alexander Zarbock , Jorge Echeverri , Kai Harenski , Ashita Tolwani
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引用次数: 0
Hospital-acquired pneumonia: Past, present, and perspectives 医院获得性肺炎:过去、现在和前景。
IF 2.9 3区 医学
Journal of critical care Pub Date : 2025-10-14 DOI: 10.1016/j.jcrc.2025.155306
Ignacio Martin-Loeches , Antoni Torres , Antoine Roquilly
{"title":"Hospital-acquired pneumonia: Past, present, and perspectives","authors":"Ignacio Martin-Loeches ,&nbsp;Antoni Torres ,&nbsp;Antoine Roquilly","doi":"10.1016/j.jcrc.2025.155306","DOIUrl":"10.1016/j.jcrc.2025.155306","url":null,"abstract":"<div><div>Hospital-acquired pneumonia (HAP) remains the most frequent and lethal hospital acquired infection, driving ICU mortality, prolonged length of stay, and resource use. Ventilator-associated pneumonia (VAP), the archetypal form of HAP, has long defined both the risks and unintended costs of intensive care. Historically, management was shaped by timelines, culture-based diagnostics, and the central role of the endotracheal tube as both lifesaving and pathogenic. This paradigm promoted rigid definitions and empiric antibiotic strategies but also generated enduring lessons on airway care, aspiration, and biofilm biology.</div><div>Contemporary perspectives have shifted toward ecology and host response. The binary early–late VAP model has been replaced by a continuum of ventilatorassociated lower respiratory tract infections (VA-LRTI), from ventilator-associated tracheobronchitis to VAP. Colonisation, biofilm formation, and microbial–host interactions are now recognised as dynamic drivers of infection. Novel diagnostics—including multiplex PCR and next-generation sequencing—offer rapid pathogen and resistance detection, while biomarkers such as procalcitonin support stewardship and shorter antibiotic courses. Recognition of ventilated HAP (VHAP) has blurred traditional boundaries.</div><div>Looking forward, precision diagnostics, immune monitoring, and artificial intelligence promise to integrate ecology and immunity into personalised management. The future of HAP care lies not in faster antibiotics, but in tailored, ecology-informed, host-guided strategies that improve outcomes and preserve resilience in the critically ill.</div></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"91 ","pages":"Article 155306"},"PeriodicalIF":2.9,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145300962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the editor: “An economic model for different anticoagulation strategies in continuous renal replacement therapy” 致编辑的信:“持续肾替代治疗中不同抗凝策略的经济模型”。
IF 2.9 3区 医学
Journal of critical care Pub Date : 2025-10-13 DOI: 10.1016/j.jcrc.2025.155292
XiRui Yang , KaiFeng Qin , YingJian Wang
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引用次数: 0
Letter to the editor: “New prognostic score for mortality in critically ill patients. Development and validation” 致编辑的信:“危重病人死亡率的新预后评分。开发和验证”。
IF 2.9 3区 医学
Journal of critical care Pub Date : 2025-10-13 DOI: 10.1016/j.jcrc.2025.155301
Yifan Shi , Shuwen Zhang
{"title":"Letter to the editor: “New prognostic score for mortality in critically ill patients. Development and validation”","authors":"Yifan Shi ,&nbsp;Shuwen Zhang","doi":"10.1016/j.jcrc.2025.155301","DOIUrl":"10.1016/j.jcrc.2025.155301","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"91 ","pages":"Article 155301"},"PeriodicalIF":2.9,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145292341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the editor: “Erythropoietin in ICU patients receiving early red blood cell transfusions: a retrospective study of the impact on transfusion requirements” 致编辑的信:“接受早期红细胞输注的ICU患者的促红细胞生成素:对输血需求影响的回顾性研究”。
IF 2.9 3区 医学
Journal of critical care Pub Date : 2025-10-13 DOI: 10.1016/j.jcrc.2025.155295
Faisal A. Shaikh, Eric J. Charles, Zoltan H. Nemeth
{"title":"Letter to the editor: “Erythropoietin in ICU patients receiving early red blood cell transfusions: a retrospective study of the impact on transfusion requirements”","authors":"Faisal A. Shaikh,&nbsp;Eric J. Charles,&nbsp;Zoltan H. Nemeth","doi":"10.1016/j.jcrc.2025.155295","DOIUrl":"10.1016/j.jcrc.2025.155295","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"91 ","pages":"Article 155295"},"PeriodicalIF":2.9,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145292330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence and predictors of adverse events during intra-hospital transport of critically ill patients in a tertiary ICU in Ethiopia: A prospective observational study 埃塞俄比亚三级ICU重症患者院内转运期间不良事件的发生率和预测因素:一项前瞻性观察研究
IF 2.9 3区 医学
Journal of critical care Pub Date : 2025-10-13 DOI: 10.1016/j.jcrc.2025.155309
Addisu G. Ayalew , Mikiyas G. Teferi , Nanati J. Aliye , Kassahun A. Dinku , Getaw W. Hassen , Fetiya Alferid
{"title":"Incidence and predictors of adverse events during intra-hospital transport of critically ill patients in a tertiary ICU in Ethiopia: A prospective observational study","authors":"Addisu G. Ayalew ,&nbsp;Mikiyas G. Teferi ,&nbsp;Nanati J. Aliye ,&nbsp;Kassahun A. Dinku ,&nbsp;Getaw W. Hassen ,&nbsp;Fetiya Alferid","doi":"10.1016/j.jcrc.2025.155309","DOIUrl":"10.1016/j.jcrc.2025.155309","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"91 ","pages":"Article 155309"},"PeriodicalIF":2.9,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145292373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of body mass index on 90-day survival in patients in cardiogenic shock treated with V-A ECMO: A propensity weighted analysis 体重指数对V-A ECMO治疗心源性休克患者90天生存率的影响:倾向加权分析
IF 2.9 3区 医学
Journal of critical care Pub Date : 2025-10-11 DOI: 10.1016/j.jcrc.2025.155284
Quentin Moyon , Jules Stern , Marc Pineton de Chambrun , Guillaume Lebreton , Marylou Para , Juliette Chommeloux , Guillaume Hékimian , Charles Edouard Luyt , Alain Combes , Romain Sonneville , Matthieu Schmidt
{"title":"Impact of body mass index on 90-day survival in patients in cardiogenic shock treated with V-A ECMO: A propensity weighted analysis","authors":"Quentin Moyon ,&nbsp;Jules Stern ,&nbsp;Marc Pineton de Chambrun ,&nbsp;Guillaume Lebreton ,&nbsp;Marylou Para ,&nbsp;Juliette Chommeloux ,&nbsp;Guillaume Hékimian ,&nbsp;Charles Edouard Luyt ,&nbsp;Alain Combes ,&nbsp;Romain Sonneville ,&nbsp;Matthieu Schmidt","doi":"10.1016/j.jcrc.2025.155284","DOIUrl":"10.1016/j.jcrc.2025.155284","url":null,"abstract":"<div><h3>Objective</h3><div>The impact of body mass index (BMI) on outcomes in refractory cardiogenic shock requiring extracorporeal membrane oxygenation (ECMO) is not well understood. We aimed to assess: (i) whether BMI is independently associated with outcomes, and (ii) whether patients with obesity (BMI &gt; 30 kg/m<sup>2</sup>) have worse outcomes than lean counterparts.</div></div><div><h3>Methods</h3><div>We conducted a retrospective analysis of a prospectively maintained database from two French ECMO centers (2006–2022). The impact of BMI was evaluated using inverse propensity-score weighted (IPSW), propensity-score (PS) matching, and multivariable (MV) models, adjusting for predefined confounders. The primary outcome was 90-day mortality. The relationship between BMI and outcomes was examined using generalized additive models. Outcomes were compared across three BMI categories (&lt;25 kg/m<sup>2</sup>, 25-30 kg/m<sup>2</sup>, and &gt; 30 kg/m<sup>2</sup>). Patients treated with extracorporeal cardiopulmonary resuscitation (<em>E</em>-CPR) were analyzed separately.</div></div><div><h3>Results</h3><div>Among 921 patients, BMI was not significantly associated with 90-day mortality (HR 0.99, 95 % CI 0.97–1.01, <em>p</em> = 0.2), despite more ECMO-related complications. This was consistent across PS-matched, IPSW, and MV models. No significant non-linear relationship between BMI and 90-day mortality was found. Among the 204 patients with ECMO during cardiopulmonary resuscitation, those with BMI &lt; or ≥ 30 kg/m<sup>2</sup> had 90-day mortality rates of 76 % and 71 %, respectively (<em>p</em> = 0.5).</div></div><div><h3>Conclusion</h3><div>Patients with obesity treated with ECMO for refractory cardiogenic shock have similar 90-day outcomes to their lean counterparts, despite higher respiratory, renal, and device-related complications.</div></div>","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"91 ","pages":"Article 155284"},"PeriodicalIF":2.9,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145265024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the editor: New prognostic score for mortality in critically ill patients. Development and validation 致编辑的信:危重病人死亡率的新预后评分。开发和验证
IF 2.9 3区 医学
Journal of critical care Pub Date : 2025-10-11 DOI: 10.1016/j.jcrc.2025.155303
Song Zhou , Yunlai Zhao , Hongying Wang
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引用次数: 0
Response to the Letters to the Editor regarding: “New prognostic score for mortality in critically ill patients. Development and validation” 对致编辑的信的回应:“危重病人死亡率的新预后评分。开发和验证”
IF 2.9 3区 医学
Journal of critical care Pub Date : 2025-10-11 DOI: 10.1016/j.jcrc.2025.155304
M.P. Gracia Arnillas , F. Alvarez Lerma , X. Nuvials Casals , R. Gimeno Costa , N. Mas Bilbao , J. Lobo Palanco , A. Escribá Bárcena , M. Catalán González , M. Martinez Alonso
{"title":"Response to the Letters to the Editor regarding: “New prognostic score for mortality in critically ill patients. Development and validation”","authors":"M.P. Gracia Arnillas ,&nbsp;F. Alvarez Lerma ,&nbsp;X. Nuvials Casals ,&nbsp;R. Gimeno Costa ,&nbsp;N. Mas Bilbao ,&nbsp;J. Lobo Palanco ,&nbsp;A. Escribá Bárcena ,&nbsp;M. Catalán González ,&nbsp;M. Martinez Alonso","doi":"10.1016/j.jcrc.2025.155304","DOIUrl":"10.1016/j.jcrc.2025.155304","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"91 ","pages":"Article 155304"},"PeriodicalIF":2.9,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145265701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the editor: Immediate “sipping” vs. delayed oral fluid intake after extubation: A randomized controlled trial 给编辑的信:拔管后立即“啜饮”vs.延迟口服液体摄入:一项随机对照试验
IF 2.9 3区 医学
Journal of critical care Pub Date : 2025-10-11 DOI: 10.1016/j.jcrc.2025.155297
Song Zhou , Yunlai Zhao , Huaiyu Mao , Guoying Wang
{"title":"Letter to the editor: Immediate “sipping” vs. delayed oral fluid intake after extubation: A randomized controlled trial","authors":"Song Zhou ,&nbsp;Yunlai Zhao ,&nbsp;Huaiyu Mao ,&nbsp;Guoying Wang","doi":"10.1016/j.jcrc.2025.155297","DOIUrl":"10.1016/j.jcrc.2025.155297","url":null,"abstract":"","PeriodicalId":15451,"journal":{"name":"Journal of critical care","volume":"91 ","pages":"Article 155297"},"PeriodicalIF":2.9,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145265702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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