Journal of clinical & experimental dermatology research最新文献_第8页

A Retrospective Study Comparing Patient Self Reported Percepts using aValidated Sensitive Scale Questionnaire between Dermatologist Diagnosed SkinConditions in a Private Clinic Setting including Sensitive Skin Syndrome 一项回顾性研究比较患者自我报告的感知使用有效的敏感量表问卷在私人诊所皮肤科医生诊断的皮肤状况，包括敏感皮肤综合征

Journal of clinical & experimental dermatology research Pub Date : 2020-01-01 DOI: 10.35248/2155-9554.20.11.518

K. Chan

{"title":"A Retrospective Study Comparing Patient Self Reported Percepts using aValidated Sensitive Scale Questionnaire between Dermatologist Diagnosed SkinConditions in a Private Clinic Setting including Sensitive Skin Syndrome","authors":"K. Chan","doi":"10.35248/2155-9554.20.11.518","DOIUrl":"https://doi.org/10.35248/2155-9554.20.11.518","url":null,"abstract":"Sensitive skin syndrome; albeit reported in many countries worldwide; remained a condition of unknown etiology and pathogenesis. Some authorities speculate it as a skin condition continuum from mild to severe, its severity is difficult to assess. Our retrospective study aimed to draw a one- year new patient’s attendee clinical data comparing the patient self -reported percepts using a validated sensitive scale questionnaire between dermatologist diagnosed skin conditions in a private clinic setting including sensitive skin syndrome. The results suggested that allergic contact dermatitis, herpes zoster and sensitive skin syndrome diagnosed patients reported a similar mean Sensitive Scale-10 scores {46.07 (N= 91), 40.72 (N=35) and 41.38 (N=84); p >0.05} respectively. The mean SS 10 score was statistically significantly different from other skin conditions like atopic dermatitis and seborrhea dermatitis and control. The patterns of percepts distribution in terms of skin irritation, general discomfort, skin itchiness, tautness and pain between allergic contact dermatitis, herpes zoster and sensitive skin syndrome were similar. Though pain is more commonly reported it herpes zoster than itch. As how a patient perceives their somatic symptoms is one of the major reasons for their dermatology health seeking behavior, our study suggested that extreme acute form of sensitive skin syndrome may have a patient percepts similar to allergic contact dermatitis, herpes zoster psychosocially significantly affecting quality of life of the sufferers.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"82 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74319139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sensitivity of Hyaluronic Acid Fillers to Hyaluronidase: An in vitro Analysis 透明质酸填充剂对透明质酸酶的敏感性:体外分析

Journal of clinical & experimental dermatology research Pub Date : 2020-01-01 DOI: 10.35248/2155-9554.20.11.517

M. Cavallini, M. Papagni, G. Trocchi

引用次数: 11

A Double Blinded, Randomized, Controlled Split-Face Study to Investigate the Efficacy of a Tailor-made Anti-Ageing Skin Care Regimen Adapted to a Genetic Skin Ageing Risk Profile 一项双盲、随机、对照的裂脸研究，旨在研究适合遗传皮肤衰老风险概况的量身定制的抗衰老护肤方案的疗效

Journal of clinical & experimental dermatology research Pub Date : 2020-01-01 DOI: 10.35248/2155-9554.20.11.527

Barbara Geusen, L. Rodrigues, Rita Matias, Bárbara Tavares, A. L. Fonseca, A. M. Silva, P. Oliveira, Marta Ferreira, Dea Zhilivoda, Géraldine Lagast

{"title":"A Double Blinded, Randomized, Controlled Split-Face Study to Investigate the Efficacy of a Tailor-made Anti-Ageing Skin Care Regimen Adapted to a Genetic Skin Ageing Risk Profile","authors":"Barbara Geusen, L. Rodrigues, Rita Matias, Bárbara Tavares, A. L. Fonseca, A. M. Silva, P. Oliveira, Marta Ferreira, Dea Zhilivoda, Géraldine Lagast","doi":"10.35248/2155-9554.20.11.527","DOIUrl":"https://doi.org/10.35248/2155-9554.20.11.527","url":null,"abstract":"Background: Available data suggests that the manifestation of aging has a strong genetic basis, which can modify an individual ‘ s susceptibility to specific skin aging signs. Proteins such as matrix metalloproteinases, aquaporins, filaggrin, superoxide dismutase and glutathione peroxidase have specific roles. Their encoding genes present single nucleotide polymorphisms resulting in different responses to skin aging for elasticity, hydration, barrier function and wrinkles. Aim: This study aimed to investigate the anti-ageing and anti-oxidant efficacy of a skin care regimen designed to address the specific needs of a certain genetic risk profile: high risk for collagen breakdown, medium risk for antioxidant production and low risk for dehydration and impaired barrier function. Methods: DNA samples of 100 participants were collected for genetic profile analysis. Of these, 24 participants presenting the most abundant genetic risk profile were enrolled on a 56 days anti-aging efficacy study of a combined treatment. The antioxidant efficacy of one investigational product was assessed for 14 participants. Results: Significant wrinkle’s depth and skin roughness improvements were found for the investigational treatment in comparison to the comparator and baseline. No variations were observed for the skin hydration and barrier function when compared to the comparator. The skin serum provided a significant antioxidant efficacy up to 24 h. Conclusion: A skin care regimen designed to address the specific needs of a genetic risk profile characterized by high risk for collagen breakdown and medium risk for low anti- oxidant production was effective on decreasing wrinkles, improving skin roughness and protecting the skin from UV oxidative damage.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"14 9","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91440792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 and the Dermatology COVID-19和皮肤病学

Journal of clinical & experimental dermatology research Pub Date : 2020-01-01 DOI: 10.35248/2155-9554.20.11.E110

Reszko Ae

引用次数: 0

Atypical Fibroxanthoma of the Scalp in a Young Woman: A Case Report 年轻女性头皮非典型纤维黄色瘤1例报告

Journal of clinical & experimental dermatology research Pub Date : 2020-01-01 DOI: 10.46889/jdr.2020.1203

K. Elboukhari, M. Bennani, S. Elloudi, Z. Douhi, H. Baybay, F. Mernissi, A. Amarti

引用次数: 0

Evaluation of Efficacy and Safety of AHPL/AYCAP/0413 Capsule and AHPL/ AYTOP/0213 Cream in Patients Suffering from Acne Vulgaris AHPL/AYCAP/0413胶囊与AHPL/ AYTOP/0213乳膏治疗寻常性痤疮的疗效及安全性评价

Journal of clinical & experimental dermatology research Pub Date : 2020-01-01 DOI: 10.35248/2155-9554.20.11.525

S. Nipanikar, V. Deshp, Cho Hs

{"title":"Evaluation of Efficacy and Safety of AHPL/AYCAP/0413 Capsule and AHPL/ AYTOP/0213 Cream in Patients Suffering from Acne Vulgaris","authors":"S. Nipanikar, V. Deshp, Cho Hs","doi":"10.35248/2155-9554.20.11.525","DOIUrl":"https://doi.org/10.35248/2155-9554.20.11.525","url":null,"abstract":"Background: Available treatments for acne vulgaris are associated with various adverse effects, which necessitate patients to opt for alternative treatment options. Objectives: To evaluate efficacy and safety of AHPL/AYCAP/0413 capsule and AHPL/AYTOP/0213 cream in subjects suffering from Acne Vulgaris. Method: A total of 62 subjects completed the study. Subjects were advised to take 2 capsules of AHPL/AYCAP/0413 twice daily orally after meals with water and apply AHPL/AYTOP/0213 cream all over the face twice a day for two months or complete resolution of acne whichever was earlier. The primary objective was to assess changes in total number of inflammatory acne lesions on face. Secondary objectives were to assess changes in total numbers of noninflammatory acne lesions, total lesion count (inflammatory and non-inflammatory), acne severity, acne scarring, signs and symptoms, skin lightening effect, post acne dark spots, adverse events and laboratory investigations. Results: The mean inflammatory acne lesion count reduced significantly from 7.94 ± 5.91 (baseline visit) to 1.89 ± 3.06 (p=0.001) at the end of treatment. Significant reduction in total numbers of non-inflammatory acne lesions, total lesion count, acne severity and signs and symptoms of acne were observed at the end of treatment. Also improvement in skin colour, severity of post acne dark spot and reduction in numbers of post acne dark spots were observed at the end of treatment. Laboratory parameters were within normal limits both at pre and post treatment. Conclusion: AHPL/AYCAP/0413 capsule and AHPL/AYTOP/0213 cream is safe and significantly effective for treatment of acne vulgaris.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"55 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89113759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Indeterminate Cells Histiocytosis 组织细胞增多症

Journal of clinical & experimental dermatology research Pub Date : 2020-01-01 DOI: 10.35248/2155-9554.11.S7.E111

Mina Haghighiabyaneh

{"title":"Indeterminate Cells Histiocytosis","authors":"Mina Haghighiabyaneh","doi":"10.35248/2155-9554.11.S7.E111","DOIUrl":"https://doi.org/10.35248/2155-9554.11.S7.E111","url":null,"abstract":"Dendritic cells comprise a large family of antigen-presenting cells whose cutaneous subset includes Langerhans cells, indeterminate cells, and dermal dendritic cells. These cells present antigens to lymphocytes, with whom they interact through specific surface receptors. The prototypical dendritic cell of the skin is the Langerhans cell [1]. Langerhans cells are derived from the bone marrow, are thought to locally renew in the skin, and express CD1a, S100, CD45, HLA-DR, and Langerin. A unique feature of Langerhans cells is the presence of Birbeck granules. Birbeck granules are recognized by the monoclonal antibody targeting Langerin (CD207), which acts as an endocytic receptor to translocate ligands from the cell surface into the Birbeck granule [1,2]. Indeterminate cells are morphologically and immunophenotypically similar to Langerhans cells. Various hypotheses regarding the origin of indeterminate cells have been published, but the most accepted theory is that indeterminate cells represent some variant of Langerhans cells with the lack of Birbeck granules and Langerin expression being reflective of Birbeck granules either not having developed yet in an immature precursor or having been lost after activation [2,3].","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"3 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90387651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of Secret on your Skin 研究皮肤上的秘密

Journal of clinical & experimental dermatology research Pub Date : 2020-01-01 DOI: 10.35248/2155-9554.11.S7.543

Saba Shahrosv

{"title":"Study of Secret on your Skin","authors":"Saba Shahrosv","doi":"10.35248/2155-9554.11.S7.543","DOIUrl":"https://doi.org/10.35248/2155-9554.11.S7.543","url":null,"abstract":"Introduction: Keratosis Pilaris (KP) is a harmless condition of the skin.it is may be a secret on your skin for a few times. There are several types of keratosis pilaris and it has been associated with pregnancy, type 1 diabetes mellitus, obesity, dry skin, allergic diseases (e.g., Atopic dermatitis) and rarely cancer. Often the lesions can appear on the face, which may be mistaken for acne. Aim: The aim of this review was to present this condition of the skin and increase information about keratosis pilaris. Methods: A detailed electronic search was carried out on the authentic databases. Review authentic data on websites/ following patients comments for correct realization their belief form keratosis pilaris and study journals about this common skin condition. Results: In most cases, the condition gradually improves before age 30. However, it can persist longer. Physician can often diagnose keratosis pilaris simply by examining the skin; tests are not needed. Physicians will often consider family history and the presence of symptoms when making the diagnosis. Conclusion: This review suggests that • Use the soaps with suitable pH • Limit your time in the water • Avoid tight clothes You should follow the suggestions above and be patient.","PeriodicalId":15448,"journal":{"name":"Journal of clinical & experimental dermatology research","volume":"40 6","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91462168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Xeroderma Pigmentosum with Acute Myeloid Leukemia and Meningiomas: Review of Literature 色素性干皮病合并急性髓性白血病和脑膜瘤:文献回顾

Journal of clinical & experimental dermatology research Pub Date : 2020-01-01 DOI: 10.35248/2155-9554.20.11.524

N. Mian, P. Kushwaha

引用次数: 0

Idiopathic Pyoderma Gangrenosum in a Toddler: Case Report 幼儿特发性坏疽性脓皮病1例报告

Journal of clinical & experimental dermatology research Pub Date : 2020-01-01 DOI: 10.35248/2155-9554.20.11.516

Waleed Alajroush, Nouf Alqahtani, A. Alfaleh

引用次数: 0