Journal of Cutaneous and Aesthetic Surgery最新文献

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Potential execution of vitiligo surgery by the most conceivable technique - which, where, and why?
Journal of Cutaneous and Aesthetic Surgery Pub Date : 2024-10-01 Epub Date: 2024-10-21 DOI: 10.25259/jcas_128_23
Sushil S Savant, Satish S Savant
{"title":"Potential execution of vitiligo surgery by the most conceivable technique - which, where, and why?","authors":"Sushil S Savant, Satish S Savant","doi":"10.25259/jcas_128_23","DOIUrl":"10.25259/jcas_128_23","url":null,"abstract":"<p><p>While various treatment options exist for vitiligo, surgical interventions have gained significant attention due to their potential for long-lasting repigmentation. Several surgical procedures have been developed, including miniature punch grafting, thin Theirsch's split-thickness skin grafting (STSG), suction blister technique, and ultrathin STSG. The decision-making process should also consider the potential risks and benefits associated with each technique. Factors such as graft survival, color match, post-operative complications, and long-term stability of repigmentation should be evaluated. In addition, patient factors such as comorbidities, skin type, and psychological impact should be carefully considered to ensure optimal surgical outcomes. We, hereby, aim to explore the potential execution of vitiligo surgery using the most conceivable technique, considering factors such as efficacy, safety, and patient-specific characteristics.</p>","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"17 4","pages":"282-291"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11621564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Smart PDOs™ and the Cartesian Technique™: A milestone in facial rejuvenation with bioactive scaffolds.
Journal of Cutaneous and Aesthetic Surgery Pub Date : 2024-10-01 Epub Date: 2024-10-21 DOI: 10.25259/jcas_191_22
Gladys Josefina Velazco de Maldonado, Dubraska Violeta Suarez-Vega, Blanca Miller-Kobisher, García-Guevara Víctor
{"title":"Smart PDOs™ and the Cartesian Technique™: A milestone in facial rejuvenation with bioactive scaffolds.","authors":"Gladys Josefina Velazco de Maldonado, Dubraska Violeta Suarez-Vega, Blanca Miller-Kobisher, García-Guevara Víctor","doi":"10.25259/jcas_191_22","DOIUrl":"10.25259/jcas_191_22","url":null,"abstract":"<p><strong>Objectives: </strong>Evaluate the controlled release of silicon from smart polydioxanone suture (Smart PDOs™) and the clinical effect of the Cartesian Technique™ in face lifting.</p><p><strong>Material and methods: </strong>This study was preclinical and clinical trials randomized, uncontrolled, and phase I carried out. Preclinical trials included instrumental analysis of silicon-enriched sutures by light microscopy, electron microscopy, and Ultraviolet-visible (UV-vis) spectroscopy. The clinical trial included 35 patients with primary and secondary rhytides, grade I lipomatosis, and grade I deflation. Polydioxanone (PDO) sutures are inserted following the Cartesian Technique™, a vectorial lift from the intersection of the Cartesian planes of the face. Once the cannulas were inserted with the PDO thread, 0.1 mL of organic silicon was dosed. Turgidity was examined by the pinch test of skin turgor. To measure the position of flaccid or deflated tissues, the scale used was the deflation scale.</p><p><strong>Results: </strong>The controlled release of organic silicon from the PDO sutures was verified. Its clinical application revealed that after 8 days the improvement in turgidity, wrinkle reversal, and flaccidity tightening was maintained in 100% of the sample. At 15 days, reversal of rhytides was observed, softening of deep furrows in 80%, and the initial turgor and skin tightening maintained without deflation in 90% of cases. Histopathological findings reveal that silicon synergistically potentiates the tissue effect of the PDO suture, generating greater biostimulation of fibroblasts with better quality collagen fibers, greater restructuring and redensification of the skin, and avoiding the late inflammatory response.</p><p><strong>Conclusion: </strong>The Cartesian Technique™ with Smart PDOs™ is an effective protocol for skin replenishment that enhances cell biostimulation through the release of bioactive drugs.</p>","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"17 4","pages":"292-306"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eyebrow reconstruction by simple elliptical excision with beveled incision - A case series of twelve patients.
Journal of Cutaneous and Aesthetic Surgery Pub Date : 2024-10-01 Epub Date: 2024-10-11 DOI: 10.25259/jcas_189_22
Yogesh M Bhingradia, Akshay Arun Vetal, Heena Singdia, Aarushi Kinjalk
{"title":"Eyebrow reconstruction by simple elliptical excision with beveled incision - A case series of twelve patients.","authors":"Yogesh M Bhingradia, Akshay Arun Vetal, Heena Singdia, Aarushi Kinjalk","doi":"10.25259/jcas_189_22","DOIUrl":"10.25259/jcas_189_22","url":null,"abstract":"<p><p>Patients seeking reconstructive facial surgery desire aesthetically pleasing outcomes with minimal visible scarring. For scalp incisions, beveled angle of 45° is typically preferred to preserve hair follicles. However, no consensus exists regarding the ideal incision angle for the brow area. This observational study analyzed the surgical outcomes of 12 patients with eyebrow defects treated using a simple elliptical excision with a beveled incision, addressing various indications such as posttraumatic scars, post-burn scars, and tumors. Outcomes were evaluated using the Physician Global Esthetic Improvement Scale at 7 days and 3 months post-surgery. At 7 days, 50% of patients showed very good improvement, and the other 50%showed moderate improvement. By 3 months, 33% of patients exhibited exceptional improvement, 50% showed very good improvement, and 17% demonstrated moderate improvement. This study concludes that direct excision and approximation with an angled incision along the hair follicle direction provide favorable aesthetic results for eyebrow reconstruction.</p>","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"17 4","pages":"325-329"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619161/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acne scars impact on the quality of life and the willingness to pay for treatments among adults in Riyadh, Saudi Arabia: A cross-sectional study. 痤疮疤痕对沙特阿拉伯利雅得成年人生活质量和治疗费用支付意愿的影响:横断面研究。
Journal of Cutaneous and Aesthetic Surgery Pub Date : 2024-07-01 Epub Date: 2024-08-29 DOI: 10.25259/jcas_154_23
Salim Alkeraye, Khalid Alosaimi, Hamad F Alrabiah, Rema Alkahtani, Naif Ahmed Alshehri, Bander Ahmed Alharbi
{"title":"Acne scars impact on the quality of life and the willingness to pay for treatments among adults in Riyadh, Saudi Arabia: A cross-sectional study.","authors":"Salim Alkeraye, Khalid Alosaimi, Hamad F Alrabiah, Rema Alkahtani, Naif Ahmed Alshehri, Bander Ahmed Alharbi","doi":"10.25259/jcas_154_23","DOIUrl":"10.25259/jcas_154_23","url":null,"abstract":"<p><strong>Objectives: </strong>Acne scarring occurs from skin damage following acne healing. Treatments such as chemical peels, dermabrasion, and laser therapy can effectively enhance scars' appearance but could be expensive. This study aimed to reflect participants' awareness of treatment options and their willingness to pay (WTP), evaluating their association with sociodemographics, severity, and quality of life (QoL).</p><p><strong>Material and methods: </strong>A cross-sectional study was conducted in Riyadh, Saudi Arabia, from June to July of 2023. Study participants were chosen using a non-probability sampling technique. Participants were aged 18 or older, had acne scarring, and resided in Riyadh. Data analysis was performed using RStudio, with <i>P</i> < 0.05 indicating statistical significance.</p><p><strong>Results: </strong>A total of 401 adult participants were included in the study. The prevalence of acne scarring among the participants was 63.4%. About 45.8% of the participants expressed a WTP of <1000 Saudi Riyals (SAR), while 42.2% were willing to pay 1000-6000 SAR. The most well-recognized acne scar management modalities were laser resurfacing (66.3%) and chemical peels (64.1%), while the least recognized were collagen/fat filler injections (23.9%) and radiofrequency microneedling (27.7%).</p><p><strong>Conclusion: </strong>The most recognized acne scar treatment modalities were laser resurfacing and chemical peels. Participants were willing to pay for reasons such as psychological impact, income levels, and awareness of treatment modalities. The findings could influence dermatologists to start awareness campaigns to debunk misconceptions about acne scar treatment modalities and their efficacy in improving QoL.</p>","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"17 3","pages":"205-213"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11497542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum interleukin-6 and high sensitivity C-reactive protein levels and their correlation with the vitiligo disease activity and extent: A cross-sectional study of 58 patients. 58例白癜风患者血清白介素-6和高敏c反应蛋白水平及其与疾病活动性和程度的相关性研究
Journal of Cutaneous and Aesthetic Surgery Pub Date : 2024-07-01 Epub Date: 2023-08-04 DOI: 10.4103/JCAS.JCAS_12_23
Bhargavi M Uttmani, Keshavmurthy A Adya, Arun C Inamadar
{"title":"Serum interleukin-6 and high sensitivity C-reactive protein levels and their correlation with the vitiligo disease activity and extent: A cross-sectional study of 58 patients.","authors":"Bhargavi M Uttmani, Keshavmurthy A Adya, Arun C Inamadar","doi":"10.4103/JCAS.JCAS_12_23","DOIUrl":"10.4103/JCAS.JCAS_12_23","url":null,"abstract":"<p><p>Vitiligo is an acquired depigmenting disorder due to the destructive loss of melanocytes, clinically presenting as hypopigmented or depigmented macules and/or patches. Many theories have been proposed to explain its etiopathogenesis among which cell-mediated immunity is one of the crucial links. Estimation of vitiligo activity and extent in a patient is important in tailoring an optimal treatment regimen. Interleukin-6 (IL-6) and high-sensitivity C-reactive protein (HsCRP) are sensitive indicators for systemic inflammation and are found to be relevant in determining vitiligo disease activity. This study was conducted to estimate serum levels of IL-6 and HsCRP in vitiligo patients and to correlate them with the disease activity and extent in order to assess if these serum markers serve as objective indicators of vitiligo disease activity. This was a hospital-based cross-sectional study of 58 vitiligo patients diagnosed clinically irrespective of age, gender, and any ongoing or past treatment. Disease activity and extent were calculated using the vitiligo disease activity (VIDA) score and vitiligo area severity index (VASI), respectively. Serum levels of IL-6 and HsCRP were obtained and their correlation with VIDA and VASI values were statistically analyzed. A weak negative statistically insignificant correlation was found between IL-6 and VIDA (P = 0.092). No correlation was found between VIDA and HsCRP (P = 0.998). A weak positive, statistically insignificant correlation was found between VASI and IL-6 as well as between VASI and HsCRP (P = 0.175 and P = 0.238, respectively). Although statistically insignificant, the patients who were not on immunosuppressive therapy showed higher mean values of IL-6 and HsCRP compared to those who were on immunosuppressive therapy. In contrast to the findings of previous studies, our study found a weak negative correlation between VIDA and IL-6 levels possibly attributable to the difference between the mean levels of IL-6 among the subgroups of patients who were, and were not on immunosuppressive therapy. The VIDA score and HsCRP levels did not show any statistical correlation. However, patients who were not on immunosuppressive therapy showed a higher albeit statistically insignificant mean value of HsCRP. Our observations suggest that any ongoing and/or treatment in the recent past, especially immunosuppressive therapy, and any co-morbidities should be essentially considered while investigating for sensitive serum markers of inflammation as determinants of vitiligo disease activity.</p>","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":" ","pages":"266-271"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11497559/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49063532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A customized syringe for separating ingrown toe nail from the gutter. 专门定制的注射器,用于将嵌甲从趾沟中分离出来。
Journal of Cutaneous and Aesthetic Surgery Pub Date : 2024-07-01 Epub Date: 2022-12-02 DOI: 10.4103/JCAS.JCAS_48_22
Muhammed Mukhtar, Nadia Mukhtar
{"title":"A customized syringe for separating ingrown toe nail from the gutter.","authors":"Muhammed Mukhtar, Nadia Mukhtar","doi":"10.4103/JCAS.JCAS_48_22","DOIUrl":"10.4103/JCAS.JCAS_48_22","url":null,"abstract":"<p><p>Ingrown toenails is a painful foot problem seen in primary care among young men. To provide immediate pain relief, some types of splints are placed in the gutter to separate it from the ingrown lateral nail. There are time-consuming and effort-intensive procedures that use available nail separators and elevators to separate the nail plate. Here, the hub of the syringe is cut obliquely to create a beveled or slant edge to create a custom nail separator which is a useful device for the easy and less painful separation of the ingrown nail plate from its gutter, which is an important stage of nail splinting.</p>","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"17 3","pages":"259-261"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11497537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative trichoscopic analysis of hair density in people attending tertiary care hospital - A cross-sectional study. 三级医院就诊者毛发密度的三镜面定量分析--一项横断面研究。
Journal of Cutaneous and Aesthetic Surgery Pub Date : 2024-07-01 Epub Date: 2024-08-29 DOI: 10.25259/jcas_66_23
Shraddha Uday Katruwar, Swapnil Shah
{"title":"Quantitative trichoscopic analysis of hair density in people attending tertiary care hospital - A cross-sectional study.","authors":"Shraddha Uday Katruwar, Swapnil Shah","doi":"10.25259/jcas_66_23","DOIUrl":"10.25259/jcas_66_23","url":null,"abstract":"<p><strong>Objectives: </strong>Hair is important to trace evidence commonly encountered in almost all criminal cases. Forensic anthropologists routinely compare the morphological characteristics of the hair samples to determine a transfer. Assessment of parameters such as hair density, hair diameter, follicular units, and empty hair follicle/yellow dots are useful for the diagnosis of various hair disorders, monitoring treatment outcomes, and research purposes. The study aimed to analyze the relationship between age and hair density.</p><p><strong>Material and methods: </strong>The present cross-sectional observational study was carried out at the Department of Dermatology at a tertiary care center. All the subjects attending the Dermatology Outpatient Department fulfilling inclusion criteria were studied. Data were collected after the approval from the Institutional Ethical Committee. The procedure was explained and a written consent was taken. Each patient's hair was parted in the middle and images from a point of roughly 5 inches from the patient's glabella were taken. The parameters such as hair thickness, hair density, hair count, follicular units, and empty hair follicles/yellow dots were noted.</p><p><strong>Results: </strong>In the present study, the majority of the study subjects belonged to the age group 26-35 years (38%), followed by 18-25 years (34.7%), 36-45 years (20.7%), and least in the age group of 46-55 years (6.7%). In the present study, the mean unit density in males was 104.78 ± 14.33 and that of females was 108.36 ± 17.60.</p><p><strong>Conclusion: </strong>Mean hair density varies concerning age group in the study population.</p>","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"17 3","pages":"194-197"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11497558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of topical application of Aloe Vera for accelerated wound healing of cutaneous burns Wound: A case report. 局部涂抹芦荟对加速皮肤烧伤伤口愈合的作用:病例报告。
Journal of Cutaneous and Aesthetic Surgery Pub Date : 2024-07-01 Epub Date: 2022-12-02 DOI: 10.4103/JCAS.JCAS_8_22
K SriHarsha Reddy, Ravi Kumar Chittoria, Nishad Kerakada, Neljo Thomas, R Srinath, T C Indushekar, V S Sriram
{"title":"Role of topical application of Aloe Vera for accelerated wound healing of cutaneous burns Wound: A case report.","authors":"K SriHarsha Reddy, Ravi Kumar Chittoria, Nishad Kerakada, Neljo Thomas, R Srinath, T C Indushekar, V S Sriram","doi":"10.4103/JCAS.JCAS_8_22","DOIUrl":"10.4103/JCAS.JCAS_8_22","url":null,"abstract":"<p><p>Aloe vera is a cactus plant that thrives in warm areas. Since ancient times, it has been used to treat acute wounds. However, the efficacy of aloe vera for burns and split-thickness skin graft (STSG) donor sites is inconclusive. In this study, we have applied pure aloe vera gel extract as an adjunct to dressing second-degree (superficial) burn wounds and assessed the time for complete epithelialization. The time taken for complete epithelialization of the wound was 11 days when compared to the normal (evidence-based) time of 14 days.</p>","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"17 3","pages":"246-248"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11497533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating the future: Ensuring quality research with open access. 引领未来:通过开放式获取确保研究质量。
Journal of Cutaneous and Aesthetic Surgery Pub Date : 2024-07-01 Epub Date: 2024-08-29 DOI: 10.25259/JCAS_58_2024
Sandeep Arora
{"title":"Navigating the future: Ensuring quality research with open access.","authors":"Sandeep Arora","doi":"10.25259/JCAS_58_2024","DOIUrl":"10.25259/JCAS_58_2024","url":null,"abstract":"","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"17 3","pages":"163-164"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11494846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study to compare the efficacy of 50% glycolic acid with 65% trichloroacetic acid in the treatment of atrophic acne scar by CROSS technique. 研究比较 50%乙醇酸和 65%三氯乙酸通过 CROSS 技术治疗萎缩性痤疮疤痕的疗效。
Journal of Cutaneous and Aesthetic Surgery Pub Date : 2024-07-01 Epub Date: 2024-08-29 DOI: 10.25259/jcas_18_21
Gourab Roy, Tirthankar Gayen, Sumit Sen, Olympia Rudra
{"title":"Study to compare the efficacy of 50% glycolic acid with 65% trichloroacetic acid in the treatment of atrophic acne scar by CROSS technique.","authors":"Gourab Roy, Tirthankar Gayen, Sumit Sen, Olympia Rudra","doi":"10.25259/jcas_18_21","DOIUrl":"10.25259/jcas_18_21","url":null,"abstract":"<p><strong>Objectives: </strong>Acne scars often become challenging to treat with satisfactory results. The chemical reconstruction of skin scars (CROSS) technique has been used with high concentrations of trichloroacetic acid (TCA) which often produces unacceptable side effects. There is a dearth of data, with 50% glycolic acid (GA) for the same indication in the management of acne scars in the Indian population. This study aimed to assess the clinical response of acne scars after the application of 50% GA with that after the use of 65% TCA in a similar manner.</p><p><strong>Material and methods: </strong>An institution-based prospective comparative study was performed with patients aged 16-45 years of either sex with acne scars and not been treated within the past 1 year. Subjects were assigned to receive one of the formulations (50% GA [Group A] and 65% TCA [Group B]). Grading of scars was done on day 1 and day 35 based on patients' assessment on a four-point visual scale and physicians' assessment by the Goodman-Baron qualitative global acne scar grading scale. The procedure was repeated every fortnightly for three such. Data were analyzed by Statistica version 6 (Tulsa, Oklahoma: StatSoft Inc. 2001).</p><p><strong>Results: </strong>The visual improvement scale of patients showed 41.38% (<i>n</i> = 12) fair improvement in group A, whereas 58.06% (<i>n</i> = 18) showed good improvement in group B. Grading by the Goodman-Baron scale showed 9.68% (<i>n</i> = 3) showed four grade changes in group B.</p><p><strong>Conclusion: </strong>Improvement is best observed with 65% TCA. Adverse effects were noted more with 65% TCA, especially acneiform eruption which was lacking in the previous studies. GA can be a safer alternative to TCA with acceptable results. Our study opens the scientific window for future research on different concentrations of GA as a CROSS agent.</p>","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"17 3","pages":"198-204"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11497540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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