Journal of Clinical Apheresis最新文献

Enhancing Apheresis Knowledge: An Educational Intervention for Non-Apheresis Medical Providers

IF 1.4 4区医学

Journal of Clinical Apheresis Pub Date : 2024-12-16 DOI: 10.1002/jca.70001

Robert Achram, E. Alexander Dent, Marianne Yee, John D. Roback, Jeannette Guarner, H. Cliff Sullivan

引用次数: 0

What's in a Name: Your PLEX or PEX Is Our TPE 名字的含义：您的 PLEX 或 PEX 就是我们的 TPE。

IF 1.4 4区医学

Journal of Clinical Apheresis Pub Date : 2024-12-16 DOI: 10.1002/jca.70000

Ziver Sahin, Aaron Christensen, Juliana Guarente, Angelica Vivero, Julie Katz Karp

引用次数: 0

Clotted Apheresis Hematopoietic Stem Cell Product

IF 1.4 4区医学

Journal of Clinical Apheresis Pub Date : 2024-12-05 DOI: 10.1002/jca.70002

Lefan Zhuang, Jennifer Woo, Franchesca Francisco, Rickey Bertram, Shirong Wang, Ryan Jackson, Shan Yuan

引用次数: 0

I-JAMM (II)-Therapeutic Apheresis Practices in Preconditioning of ABO-Incompatible Kidney and Liver Transplants in India.

IF 1.4 4区医学

Journal of Clinical Apheresis Pub Date : 2024-12-01 DOI: 10.1002/jca.70003

Prashant Pandey, Arghyadeep Marik, Aseem Tiwari, Sudipta Shekhar Das, Shamee Shastry, Vivek Kute, Mohit Chowdhry, Supriya Kumari, Divya Setya

{"title":"I-JAMM (II)-Therapeutic Apheresis Practices in Preconditioning of ABO-Incompatible Kidney and Liver Transplants in India.","authors":"Prashant Pandey, Arghyadeep Marik, Aseem Tiwari, Sudipta Shekhar Das, Shamee Shastry, Vivek Kute, Mohit Chowdhry, Supriya Kumari, Divya Setya","doi":"10.1002/jca.70003","DOIUrl":"https://doi.org/10.1002/jca.70003","url":null,"abstract":"ABO-incompatible transplantations are increasingly gaining relevance with advancements in therapeutic modalities, thus allowing patients to receive timely solid organ transplants. Therapeutic apheresis (TA) procedures remain instrumental as a preconditioning measure to enable such transplants. This survey was undertaken to find out current trends and practices of TA across major transplant centers in India. The survey was drafted by a working group of transfusion and transplant immunology specialists from six different centers in India. Data were obtained via the use of an online questionnaire. Results were categorized into eight categories: hospital information, range of titers for preconditioning, considerations prior to starting TA, TA procedure details, role of pharmacotherapy in TA, policy for reuse of columns, risk of rebound, and the role of transfusion medicine specialists. The survey highlighted the modalities as well as the methodologies of various TA procedures used across different major transplant centers in India. With the increase in ABO-incompatible kidney and liver transplants across the country, the role of transfusion medicine and transplant immunology specialists have become vital in preconditioning regimes enabling the viability and success of such transplants. This was a unique survey that provided us a snapshot of current trends and practices of TA in preconditioning of patients for ABO-incompatible transplants in India.","PeriodicalId":15390,"journal":{"name":"Journal of Clinical Apheresis","volume":"39 6","pages":"e70003"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Annual Review of Important Apheresis Articles From the American Society for Apheresis Attending Physician Subcommittee 美国血液净化学会主治医师小组委员会重要血液净化文章年度回顾。

IF 1.4 4区医学

Journal of Clinical Apheresis Pub Date : 2024-11-20 DOI: 10.1002/jca.22152

Yvette C. Tanhehco, Mohamed Alsammak, Ding Wen Wu, Victoria Costa, Vishesh Chhibber, Yosef Levenbrown, Yanhua Li, Wen Lu, Adela D. Mattiazzi, Laura D. Stephens, Daniel K. Noland, Marisa C. Saint Martin, Nirupama Singh, Nicole D. Zantek, Joanne Becker, Gay Wehrli

{"title":"An Annual Review of Important Apheresis Articles From the American Society for Apheresis Attending Physician Subcommittee","authors":"Yvette C. Tanhehco, Mohamed Alsammak, Ding Wen Wu, Victoria Costa, Vishesh Chhibber, Yosef Levenbrown, Yanhua Li, Wen Lu, Adela D. Mattiazzi, Laura D. Stephens, Daniel K. Noland, Marisa C. Saint Martin, Nirupama Singh, Nicole D. Zantek, Joanne Becker, Gay Wehrli","doi":"10.1002/jca.22152","DOIUrl":"10.1002/jca.22152","url":null,"abstract":"<div>\u0000 \u0000 In this first annual review article, the American Society for Apheresis (ASFA) Attending Physician Subcommittee (APSc) of the Physicians' Committee (PC) curated key apheresis literature in 2023 and presented their choices for the 10 most seminal apheresis articles. PubMed and OVID search engines were used to identify manuscripts from four topic areas: donor apheresis, therapeutic apheresis, education, and cellular therapy. To further identify seminal criteria, they had to present at least one of the following: novel findings, practice-altering outcomes, international scope, randomized controlled trial, relevant to current clinical practice, and/or provide evidence for category III or IV indications based on the ASFA ninth special issue of the Guidelines on the Use of Therapeutic Apheresis in Clinical Practice-Evidence-Based Approach. Inclusion criteria included: full-length, peer-reviewed, English language, and human subjects. Case reports, review articles, and meta-analyses were excluded.\u0000 </div>","PeriodicalId":15390,"journal":{"name":"Journal of Clinical Apheresis","volume":"39 6","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mystery Solved: Acquired Hemoglobin After Red Cell Exchange on Sickle Cell Patient 谜团解开：镰状细胞患者红细胞置换后获得性血红蛋白。

IF 1.4 4区医学

Journal of Clinical Apheresis Pub Date : 2024-11-13 DOI: 10.1002/jca.22148

Nada Naiyer, David Keren, Chisa Yamada

引用次数: 0

Therapeutic Plasma Exchange for the Symptomatic Treatment of Scleromyxedema: A Case Report and Literature Review 血浆置换治疗性硬肿症：病例报告与文献综述

IF 1.4 4区医学

Journal of Clinical Apheresis Pub Date : 2024-11-11 DOI: 10.1002/jca.22153

Matthew H. Lanehart, Erika S. Johnson, Nicole A. Aqui

{"title":"Therapeutic Plasma Exchange for the Symptomatic Treatment of Scleromyxedema: A Case Report and Literature Review","authors":"Matthew H. Lanehart, Erika S. Johnson, Nicole A. Aqui","doi":"10.1002/jca.22153","DOIUrl":"10.1002/jca.22153","url":null,"abstract":"Scleromyxedema is a rare skin mucinosis often associated with systemic involvement and monoclonal gammopathy (MG). No formal recommendation for management with therapeutic plasma exchange (TPE) has been published due to rarity. This paper reports a 42-year-old male with progressive scleromyxedema. The patient was treated with glucocorticoids, immunosuppressants, and intravenous immunoglobulin (IVIG) therapy, but the disease progressed. Ultimately, the patient was referred for TPE, which resulted in decreased skin stiffness, improved extremity range of motion, and decreased visibility of papules on the hands. The patient's debilitating dysphagia gradually improved. A review of the literature focusing on clinical response identified five cases of scleromyxedema patients treated with TPE. Three of the five cases reported significant improvement in cutaneous symptoms and range of motion for at least 12 months. Overall, we propose that TPE should be considered an effective supportive treatment for symptomatic relief in severe or refractory scleromyxedema.","PeriodicalId":15390,"journal":{"name":"Journal of Clinical Apheresis","volume":"39 6","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jca.22153","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142621416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Therapeutic Plasma Exchange Management for a Pediatric Patient Presenting With Immune Thrombotic Thrombocytopenic Purpura in a Setting of Common Variable Immunodeficiency 对一名患有免疫性血小板减少性紫癜的常见变异性免疫缺陷儿进行治疗性血浆置换。

IF 1.4 4区医学

Journal of Clinical Apheresis Pub Date : 2024-11-07 DOI: 10.1002/jca.22154

Albert Budhipramono, Ruchika Sharma, Christian Allen Wysocki, Ayesha N. Zia, Brian D. Adkins

{"title":"Therapeutic Plasma Exchange Management for a Pediatric Patient Presenting With Immune Thrombotic Thrombocytopenic Purpura in a Setting of Common Variable Immunodeficiency","authors":"Albert Budhipramono, Ruchika Sharma, Christian Allen Wysocki, Ayesha N. Zia, Brian D. Adkins","doi":"10.1002/jca.22154","DOIUrl":"10.1002/jca.22154","url":null,"abstract":"Common variable immunodeficiency (CVID) is a disorder characterized by hypogammaglobulinemia resulting in recurrent infections. While autoimmune disorders are common in patients with CVID, no association has been reported between CVID and immune thrombotic thrombocytopenic purpura (iTTP), a disorder most often caused by autoantibodies that compromise the activity of the enzyme ADAMTS13. Reduced ADAMTS13 activity results in the accumulation of large von Willebrand factor multimers that can consume platelets and cause microvascular thrombosis and organ injury, ultimately resulting in mortality in most cases of untreated iTTP. Here, we report a 12-year-old male with CVID who developed iTTP, underwent therapeutic plasma exchange (TPE), and subsequently recovered. We conducted a systematic review for other cases of CVID co-occurring with iTTP and present additional cases of this rare presentation. We highlight the importance of prompt recognition of iTTP in a patient with CVID and timely initiation of TPE.","PeriodicalId":15390,"journal":{"name":"Journal of Clinical Apheresis","volume":"39 6","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jca.22154","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mobilization and Apheresis Collection Strategies to Reduce Platelet Loss in G-CSF Mobilized Healthy Adult Donors 减少G-CSF动员的健康成人捐献者血小板损失的动员和无细胞采集策略。

IF 1.4 4区医学

Journal of Clinical Apheresis Pub Date : 2024-11-07 DOI: 10.1002/jca.22150

Brittany Castro, Jane Huang, Julie Le, Diana Pascua, Hirona Goto, Denise Kirby, David Lin

{"title":"Mobilization and Apheresis Collection Strategies to Reduce Platelet Loss in G-CSF Mobilized Healthy Adult Donors","authors":"Brittany Castro, Jane Huang, Julie Le, Diana Pascua, Hirona Goto, Denise Kirby, David Lin","doi":"10.1002/jca.22150","DOIUrl":"10.1002/jca.22150","url":null,"abstract":"<div>\u0000 \u0000 Granulocyte-colony stimulating factor (G-CSF) mobilizes hematopoietic progenitor cells (HPC) into the peripheral blood. Donor peripheral blood platelet loss has been observed during both G-CSF mobilization and apheresis collection. This study evaluates two strategies to reduce donor platelet loss, preserve product CD34+ cell yield and collection efficiency and increase volume of whole blood (WB) processed. One hundred and two adults healthy donors were mobilized with either standard dose G-CSF (9.5–12 mcg/kg/day × 4 days) or lower dose G-CSF (7.5–10 mcg/kg/day × 4 days) according to their pre-mobilization platelet count. Apheresis centrifugal force was adjusted by lowering the packing factor (PF) setting on the apheresis instrument. Between-group differences were observed in absolute donor platelet loss (p = 0.04) favoring lower G-CSF dosing, while percent donor platelet loss trended towards significance (p = 0.10). Lowering PF from the manufacturer's default of 4.5 to 4.0 demonstrated between-group differences in absolute donor platelet loss (p < 0.05), percent donor platelet loss (p < 0.001), and apheresis product platelet content (p < 0.001). No differences were observed in the product CD34+ cell content and CD34+ cell collection efficiency when PF was reduced to 4.0. Additionally, a higher volume of WB could be processed due to reduced donor platelet loss. Together, these two strategies may mitigate the risk of cumulative platelet loss in G-CSF mobilized healthy donors undergoing apheresis collection, thereby increasing the likelihood of completing the target total blood volume to be processed while maintaining donor safety.\u0000 </div>","PeriodicalId":15390,"journal":{"name":"Journal of Clinical Apheresis","volume":"39 6","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of a Standardized Regimen of Therapeutic Plasma Exchange and IVIG for Treatment of Antibody-Mediated Rejection in Lung Transplant Recipients 治疗性血浆置换和 IVIG 标准方案治疗肺移植受者抗体介导的排斥反应的疗效。

IF 1.4 4区医学

Journal of Clinical Apheresis Pub Date : 2024-11-07 DOI: 10.1002/jca.22151

Amelework Wodajo, Ravi Sarode, Nicole De Simone, Vaidehi Kaza, Amena Usmani

{"title":"Efficacy of a Standardized Regimen of Therapeutic Plasma Exchange and IVIG for Treatment of Antibody-Mediated Rejection in Lung Transplant Recipients","authors":"Amelework Wodajo, Ravi Sarode, Nicole De Simone, Vaidehi Kaza, Amena Usmani","doi":"10.1002/jca.22151","DOIUrl":"10.1002/jca.22151","url":null,"abstract":"Antibody-mediated rejection (AMR) in lung transplantation has been associated with poor long-term clinical course and is a risk factor for chronic lung allograft dysfunction and graft loss. Appropriate management of AMR is necessary to improve graft survival in lung transplant recipients. There is currently no standardized approach to the treatment of lung AMR, and practices vary by institution. We sought to examine the efficacy of a standardized protocol of plasma exchange (PLEX) and IVIG in decreasing donor-specific antibodies (DSAs) and improving AMR in lung transplant recipients. A retrospective chart review was conducted on all lung transplant recipients who completed a course of PLEX per UT Southwestern AMR protocol between January 2012 and December 2019 for diagnosis of AMR. Data were collected on the patient clinical course, treatment regimen, pre-PLEX DSA, post-PLEX DSA, follow-up (> 1-month post-PLEX) DSA, and pre-and post-PLEX biopsy, when available. Of 527 patients who underwent lung transplantation during the study period, 56 (11%) received an acute course of PLEX every other day per protocol for AMR of lung transplant. Forty (71%) of 56 patients had one episode of AMR requiring PLEX; 16 patients (29%) had repeat episodes of AMR within 6 weeks to 47 months of the first episode. Most patients showed improvement in AMR on biopsy (69%) and a decline in DSA (68%). Our data suggest that treatment with combined PLEX and IVIG protocol appears effective for treating lung AMR.","PeriodicalId":15390,"journal":{"name":"Journal of Clinical Apheresis","volume":"39 6","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jca.22151","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0