Journal of Chemical Health Risks最新文献_第6页

Determination of the Concentration of Heavy Metals and Their Assessment of Related Potential Health Risk for Dry Black Teas in Kashan, Iran 伊朗卡山干红茶重金属浓度测定及潜在健康风险评价

Journal of Chemical Health Risks Pub Date : 2020-05-01 DOI: 10.22034/JCHR.2020.1891622.1094

Nedasadat Seyyedi Bidgoli, G. Mostafaii, H. Akbari, E. Chimehi, M. Miranzadeh

引用次数: 1

Lactobacillus paracasei Impact on Myocardial Hypertrophy in Rats with Heart Failure 副干酪乳杆菌对心力衰竭大鼠心肌肥大的影响

Journal of Chemical Health Risks Pub Date : 2020-02-26 DOI: 10.22034/JCHR.2020.1888659.1080

Zohreh Hesari, Khatereh Kafshdoozan, M. Barati, P. Kokhaei, S. Andalib, Fatemeh TalebiKiassari, M. Darban, A. Abdolshahi, B. Bagheri

{"title":"Lactobacillus paracasei Impact on Myocardial Hypertrophy in Rats with Heart Failure","authors":"Zohreh Hesari, Khatereh Kafshdoozan, M. Barati, P. Kokhaei, S. Andalib, Fatemeh TalebiKiassari, M. Darban, A. Abdolshahi, B. Bagheri","doi":"10.22034/JCHR.2020.1888659.1080","DOIUrl":"https://doi.org/10.22034/JCHR.2020.1888659.1080","url":null,"abstract":"Cardiac hypertrophy and cardiac dysfunction are important complications of heart failure. Cardiovascular, immunological, and hormonal players are involved in the pathogenesis of heart failure. Current evidence suggests that probiotics may have fruitful effects on the heart function. This was our aim. To this end, effects of oral administration of Lactobacillus paracasei subsp. paracasei 8700:2 on isoproterenol-induced heart failure were investigated. Forty male Wistar rats weighing 200 g were randomly assigned to five groups; the control group (saline-treated group), probiotic-treated group, heart failure group (isoproterenol-introduced group), pretreatment group (treating them by probiotic for 20 days then induced heart failure) and treatment group (following heart failure-induced, treating them by probiotic for 20 days). The groups were studied for 30 days. Serum levels of atrial natriuretic peptide (ANP) and chemerin were measured by ELISA. Finally, the hearts were removed for histopathological evaluation. Compared to the control group, isoproterenol caused cardiac hypertrophy and increased ANP (P < 0.05) and chemerin levels. Treatment with Lactobacillus paracasei significantly reduced the levels of ANP (P < 0.01) and decreased the pathological damages to the myocardium. It caused a small reduction in chemerin level, as well. Pretreatment with probiotics had no positive effects on cardiac hypertrophy and related parameters. Our findings indicate that treatment with Lactobacillus paracasei subsp. paracasei 8700:2 reduces cardiac hypertrophy in rats. In addition, this probiotic reduces the serum levels of chemerin and ANP.","PeriodicalId":15347,"journal":{"name":"Journal of Chemical Health Risks","volume":"10 1","pages":"67-74"},"PeriodicalIF":0.0,"publicationDate":"2020-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42199699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Cardiovascular Disease risk Factors in Male Cigarette Smokers in Calabar, Southern Nigeria 尼日利亚南部卡拉巴尔男性吸烟者心血管疾病危险因素

Journal of Chemical Health Risks Pub Date : 2020-02-01 DOI: 10.22034/JCHR.2020.1869928.1032

I. Bassey, U. Akpan, I. Okafor, I. Inyang, O. Eze

{"title":"Cardiovascular Disease risk Factors in Male Cigarette Smokers in Calabar, Southern Nigeria","authors":"I. Bassey, U. Akpan, I. Okafor, I. Inyang, O. Eze","doi":"10.22034/JCHR.2020.1869928.1032","DOIUrl":"https://doi.org/10.22034/JCHR.2020.1869928.1032","url":null,"abstract":"Cigarette smoking has been linked to atherosclerosis, coronary artery disease, peripheral vascular disorders and various malignancies. However, the mechanism by which smoking increases the risk of cardiovascular diseases is still controversial. One hundred and forty one apparently healthy male cigarette smokers and sixty apparently healthy non-smokers aged 18 to 65 years were enrolled into the study. The smokers were sub-divided into light ( 30 pack years) smokers. Anthropometric indices and blood pressure were measured. Fasting plasma glucose, total cholesterol (TC), triglycerides and High density lipoprotein-cholesterol (HDL-C) were estimated using colorimetric test methods while low density lipoprotein-cholesterol (LDL-C) and very low density lipoprotein were calculated using Friedewald’s equation. Serum insulin was estimated using ELISA. Data was analyzed using SPSS version 20.0; level of significance was set at p<0.05. The smokers had significantly higher diastolic BP (p=0.0001), TC (p= 0.008) and LDL-C (p = 0.0001) and significantly lower HDL-C (p = 0.0001) compared to the non-smokers. There was a significant higher fasting plasma glucose in the light smokers (p=0.001) than in the moderate and heavy smokers whereas, serum TC and LDL-C levels were significantly increased in heavy smokers (p=0.001) than in the light and moderate smokers. There was a negative correlation between BMI and smoking pack years. Dyslipidaemia was observed to be the most prevalent cardiovascular disease risk factor. It is concluded that the alterations in lipid profile and blood pressure observed in this study may contribute to higher risk of cardiovascular disease.","PeriodicalId":15347,"journal":{"name":"Journal of Chemical Health Risks","volume":"10 1","pages":"25-34"},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42756403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Process Parameter on Crude Oil Biodegradation of Palm Oil Mill Effluent using Response Surface Optimization 响应面优化研究工艺参数对棕榈油厂废水原油生物降解的影响

Journal of Chemical Health Risks Pub Date : 2019-04-25 DOI: 10.22034/JCHR.2019.664497

Ani Kingsley Amechi, Eze Felix

{"title":"Effects of Process Parameter on Crude Oil Biodegradation of Palm Oil Mill Effluent using Response Surface Optimization","authors":"Ani Kingsley Amechi, Eze Felix","doi":"10.22034/JCHR.2019.664497","DOIUrl":"https://doi.org/10.22034/JCHR.2019.664497","url":null,"abstract":"Crude oil; Contaminated soil; Palm oil mill effluent; First order kinetics; second order kinetics; Error analysis; RSM ABSTRACT: The aim of this study was to investigate the effects of process parameter on crude oil (CO) biodegradation of palm oil mill effluent (POME) by using response surface optimization. Physiochemical characterization of the uncontaminated soil (UCS), crude oil contaminated soils (COCS), and POME were investigated. Further characterization on the POME was done employing the scanning electron microscope (SEM) and Fourier transform infrared (FT-IR). First and second order kinetics models were used to estimate the kinetic parameters. Results obtained indicated that POME contained valuable soil nutrient as it showed a stimulatory effect on the physiochemical properties of the COCS. However, POME was able to degrade 51% of CO with an initial CO concentration of 130 g/L. The first order kinetics proved a better model with a high rate constant, lower biological half-life and R2 greater than 0.96. From the optimization process, the quadratic model with 78.8% contribution and R2 of 0.993 satisfactorily explained the interactions between the independent variable and the response. The FT-IR spectrum revealed the presence of nitrogen and phosphorous on the surface of POME, while SEM indicated a smooth surface of POME.","PeriodicalId":15347,"journal":{"name":"Journal of Chemical Health Risks","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49063498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and Cytotoxic Evaluation of 2-Pyrazoline Derivative on Leukemia Cancer Cell Line K562 2-吡唑啉衍生物的合成及其对白血病癌症细胞株K562细胞毒性的评价

Journal of Chemical Health Risks Pub Date : 2018-12-26 DOI: 10.22034/JCHR.2018.545324

M. Shaabanzadeh, M. Torbati

{"title":"Synthesis and Cytotoxic Evaluation of 2-Pyrazoline Derivative on Leukemia Cancer Cell Line K562","authors":"M. Shaabanzadeh, M. Torbati","doi":"10.22034/JCHR.2018.545324","DOIUrl":"https://doi.org/10.22034/JCHR.2018.545324","url":null,"abstract":"The 2-pyrazoline derivatives have a wide range of biological effects, such as anti-viral, anti-bacterial, anti-fungal, anti-depressant and anti-cancer effects. Studies have shown that compounds containing 2-pyrazoline along with another heterocycles may show more effective biological properties. In this study, a 2-pyrazoline derivative with a spiro-indenoquinoxaline ring at C3 position was synthesized by one-pot microwave-assisted method and its chemical structure was confirmed by 1H NMR spectroscopy. The cytotoxic effects of the compound were evaluated on the K562 cell line and phytohemagglutinin-activated peripheral blood mononuclear cells (PHA+PBMC) by MTT assay. Additionally, the cytotoxic effects of cisplatin on these cells were investigated and compared with those of 2-pyrazoline. The IC50 values obtained from the 2-pyrazoline derivative effects on the K562 cell line and PHA+PBMC cells were 45 and 55 μg/mL respectively, while cisplatin inhibited proliferation of the same cells with IC50 value 1.71 and 7.8 µg/mL respectively. The results of this study showed that the synthesized derivative had a cytotoxic activity on the K562 cancer cell line at higher concentrations than cisplatin.","PeriodicalId":15347,"journal":{"name":"Journal of Chemical Health Risks","volume":"13 1","pages":"323-328"},"PeriodicalIF":0.0,"publicationDate":"2018-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41293528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Distribution and Toxicological Risk Evaluation of Pb, Cd, As and Zn from Surface Soils of Selected Marts in Port Harcourt, Rivers State, Nigeria 尼日利亚河流州哈科特港部分火星表层土壤中Pb、Cd、As和Zn的分布和毒理学风险评估

Journal of Chemical Health Risks Pub Date : 2018-12-01 DOI: 10.22034/JCHR.2018.544142

J. O. Osuoha, Chidiebere Uchenna Iheka, P. Amadi, I. Archibong, O. Adeoti

{"title":"Distribution and Toxicological Risk Evaluation of Pb, Cd, As and Zn from Surface Soils of Selected Marts in Port Harcourt, Rivers State, Nigeria","authors":"J. O. Osuoha, Chidiebere Uchenna Iheka, P. Amadi, I. Archibong, O. Adeoti","doi":"10.22034/JCHR.2018.544142","DOIUrl":"https://doi.org/10.22034/JCHR.2018.544142","url":null,"abstract":"It is very pertinent to carry out environmental studies for the assessment of human health risks associated with heavy metal accumulation of frequently visited environments. By Atomic Absorption Spectrophotometry, Lead (Pb), Zinc (Zn), Cadmium (Cd) and, Arsenic (As) were analyzed in top soil samples from Rumuokoro mart (RUM), Choba mart, Mile 3 mart, Mile 1 mart , Town mart (TM), Trans-Amadi mart (TRANS), Boundary mart (BOUND), Oil mill mart (OIL M), Eleme mart (ELE). The concentration of zinc was highest in the mart sites among the other metals. There was pollution with some of the heavy metals at some mart sites. The highest I geo was found for cadmium at TRANS. The study further established contamination with some of the metals in some of the mart sites as very high contamination with arsenic was observed in RUM. The enrichment factor result obtained revealed that all the metals in all the mart sites occurred as a result of anthropogenic origin except that of lead in MILE 3 that was from natural activities. The levels of average daily intake of all the metals in all the sites were found to be below their respective reference doses. The highest average daily intake of all the metals investigated was observed in zinc at BOUND. No significant health hazard could result from the levels of the metals deposited in the study sites as they did not exceed the reference level at 1.0. RUM is observed as the likely mart site vulnerable to significant health hazards of all sites assessed. Regular environmental assessment should be performed in order monitor and regulate these metals in order to minimize health risks.","PeriodicalId":15347,"journal":{"name":"Journal of Chemical Health Risks","volume":"8 1","pages":"255-264"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46981365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effect of Sulfur Application on Growth, Photosynthetic Pigments, Antioxidant Activity and Arsenic Accumulation in Coriander (Coriandrum sativum) under Arsenic Stress 施硫对砷胁迫下香菜生长、光合色素、抗氧化活性及砷积累的影响

Journal of Chemical Health Risks Pub Date : 2018-12-01 DOI: 10.22034/JCHR.2018.544686

Hosein Asadi Ghalehni, V. Poozesh

{"title":"Effect of Sulfur Application on Growth, Photosynthetic Pigments, Antioxidant Activity and Arsenic Accumulation in Coriander (Coriandrum sativum) under Arsenic Stress","authors":"Hosein Asadi Ghalehni, V. Poozesh","doi":"10.22034/JCHR.2018.544686","DOIUrl":"https://doi.org/10.22034/JCHR.2018.544686","url":null,"abstract":"Soils polluted with toxic elements are one of the major environmental problems in human societies. Sulfur (S), an essential element for the growth and development plants, plays an important role in reducing the toxicity of toxic elements as arsenic. In this study, the role of Sulfur different regimes (0, 50, 100 and 150 mg per kg) in reducing arsenic (As) toxicity in coriander (Coriandrum sativum) was investigated. The obtained results indicated that Sulfur application increased the activities of antioxidant enzymes and photosynthetic pigments, but it’s decreased the arsenic induced oxidative stress. Reduction of shoot and root biomass occurred in presence of sulfur different regimes and As various concentrations. S supplement under high As concentration increased protein content of shoot. Different S regimes resulted in enhanced both shoot and root As accumulation. Meanwhile, different treatments of sulfur allowed high translocation of As quantities from root to shoot. It is well illustrated that phytoextraction is one of the best methods for toxic metals phytoremediation. Thus from present study it is evident that the phytoremediation ability of plants for accumulates toxic metals may be enhanced through exogenous sulfur application.","PeriodicalId":15347,"journal":{"name":"Journal of Chemical Health Risks","volume":"8 1","pages":"265-276"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42934921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Removal of Heavy Metal Ions from Polluted Waters by Using of Low Cost Adsorbents: Review 低成本吸附剂对污染水中重金属离子的去除研究进展

Journal of Chemical Health Risks Pub Date : 2018-10-29 DOI: 10.22034/JCHR.2018.544016

M. Ghaedi

引用次数: 15

The Phytochemical Changes of Violet Flowers (Viola cornuta) Response to Exogenous Salicylic Acid Hormone 紫罗兰（Viola cornuta）对外源水杨酸激素反应的植物化学变化

Journal of Chemical Health Risks Pub Date : 2018-10-29 DOI: 10.22034/JCHR.2018.544042

N. Ghorbani, H. Moradi, V. Akbarpour, A. Ghasemnezhad

{"title":"The Phytochemical Changes of Violet Flowers (Viola cornuta) Response to Exogenous Salicylic Acid Hormone","authors":"N. Ghorbani, H. Moradi, V. Akbarpour, A. Ghasemnezhad","doi":"10.22034/JCHR.2018.544042","DOIUrl":"https://doi.org/10.22034/JCHR.2018.544042","url":null,"abstract":"Violet is one of the ornamental plants with a good value in landscaping and herbal medicine. Salicylic acid is a signaling agent involving in secondary metabolite production. The aim of this study was to evaluate the physiological responses of violet flowers to exogenous salicylic acid. This experiment was conducted in the greenhouse, as a completely randomized design. Salicylic acid was sprayed on violet plants in four levels as , , , mM and three replications. Flower diameter, flower stem length, fresh weight and dry matter percentage of violet flower were measured as morphological parametes. In laboratory parameters like antioxidant activity and anthocyanin variation were recorded using spectrophotometery method. The quercetin and rutin values were determined by HPLC. Results showed that salicylic acid significantly affected on flower diameter, total antioxidant capacity, rutin and quercetin contents. Therefore data analysis provides that high levels of salicylic acid increased morphological parameters and improved chemical substance involving to secondary metabolism promotion. Furthermore, using different concentrations of the hormone is required, to achieve the best quality and quantity of plant biomass and it is also necessary to achieve the best traits of ornamental and medicinal value","PeriodicalId":15347,"journal":{"name":"Journal of Chemical Health Risks","volume":"3 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2018-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47095932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Modeling the Chlorine Gas Dispersion in the Water Treatment Plant 水处理厂氯气扩散模拟

Journal of Chemical Health Risks Pub Date : 2018-10-29 DOI: 10.22034/JCHR.2018.544205

Hadi Shamizadeh, R. A. Shahabi, M. Arjmand

{"title":"Modeling the Chlorine Gas Dispersion in the Water Treatment Plant","authors":"Hadi Shamizadeh, R. A. Shahabi, M. Arjmand","doi":"10.22034/JCHR.2018.544205","DOIUrl":"https://doi.org/10.22034/JCHR.2018.544205","url":null,"abstract":"An issue rose for industrial safety and successful address of crisis involves quick and pragmatic decision that would reduce losses and accidents. This will become practical when in addition to studying of past accidents the industrial executives create the necessary readiness to face risks through precise estimation of the consequences of eventual accidents. The present research concerns modeling the consequences of chlorine gas dispersion in the wastewater installations. The transfer of knowledge and information in this study were gained from modeling the dispersion of chlorine in the water treatment plants, useful for managers and executives. Detection and specifying the risks of chlorine for the public and especially the staff and those residing near the water treatment plant, would result in the appropriate action against this lethal substance, which is the subject of this study. Identification of risks related to foreign agents and their negative impacts on water treatment plants containing chlorine tanks is among the objectives of this study. The modeling and accurate specification of the scope and level of danger created following the dispersion of chlorine was done using the PHAST software, which allowed a clear identification of danger zones created by the dispersion of Chlorine. This text reports the radius of areas affected by chlorine dispersion as well as the results of different conditions after running the model for variable physical and process conditions, and given their availability, these results can be compared with each other.","PeriodicalId":15347,"journal":{"name":"Journal of Chemical Health Risks","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42489472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0