{"title":"A Method for the Estimation of the Timing of Heart Sound Components Through Blind Source Separation in Multi-Source Phonocardiography","authors":"N. Giordano, M. Knaflitz","doi":"10.1109/MeMeA49120.2020.9137315","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137315","url":null,"abstract":"Recently, phonocardiography (PCG) has gained importance as a diagnostic tool for cardiovascular diseases. In particular, the measurement of the time of occurrence of heart sounds may be of interest, in the clinical context, for the analysis of the electromechanical coupling of the heart. To date, though, there is no standardization concerning the positioning of the microphone probe over the chest, and this causes low accuracy and consistency in the measured timing values. Multi-source phonocardiography is a promising approach to face the stated issue. In this work, we present a methodology to estimate the latency of the components of the two main heart sounds towards the corresponding R-wave peak based on the Blind Source Separation (BSS) of the contributions of the left and right side of the heart. We tested our algorithm on a sample population of 12 subjects over 10-minute long recordings of three simultaneous PCG signals and one electrocardiographic (ECG) signal for reference. Results show that the approach is robust with respect to the usage of different algorithms to perform BSS (FastICA, JADE). The measured timing values are consistent with what measured by means of a single-source algorithm we previously developed. This methodology looks promising in terms of obtaining accurate measurements of the time of occurrence of heart sound components and may have an impact in the clinical context.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116305797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cheng-Ru Li, H. Tsai, Chih-Chung Yang, Ming-Yen Lin, Kuo-Cheng Huang, Yu-Hsuan Lin
{"title":"Quantifying the color changes in bruised skin using a color-calibrated imaging system","authors":"Cheng-Ru Li, H. Tsai, Chih-Chung Yang, Ming-Yen Lin, Kuo-Cheng Huang, Yu-Hsuan Lin","doi":"10.1109/MeMeA49120.2020.9137217","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137217","url":null,"abstract":"The color of human skin can indirectly reflect the course of certain diseases, especially trauma or chronic diseases. Traditionally, doctors inspect and notice the abnormalities in the patient's skin color and then perform further examinations, such as blood or urine tests. The color of the skin can only be seen as a reference through the naked eye. To quantify it depends on a measurement system with precise lighting control and color correction procedures. In this study, an imaging system with color correction was developed to quantify the color of the skin. Through the composition of high color rendering lighting, dark room module, camera and polynomial regression algorithm to achieve the standard color difference (ΔE*) of less than 3. Measurements of artificial bruise and novel analytical methods were performed and developed to verify its performance. The results show that the developed system has the advantages of portability, high uniformity and high color accuracy. This research has successfully developed a novel inspection method for medical diagnostics, forensic science, and related applications.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114715195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Selzler, Andrew Smith, François Charih, A. Boyle, Janet Holly, Courtney Bridgewater, M. Besemann, Dorothyann Curran, A. Chan, J. Green
{"title":"Exploratory Analysis of Ultra-Short-Term Heart Rate Variability Features in Virtual Rehabilitation Sessions","authors":"R. Selzler, Andrew Smith, François Charih, A. Boyle, Janet Holly, Courtney Bridgewater, M. Besemann, Dorothyann Curran, A. Chan, J. Green","doi":"10.1109/MeMeA49120.2020.9137133","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137133","url":null,"abstract":"We are currently collecting multi-modal data from patients undergoing rehabilitation therapy using virtual reality for mild traumatic brain injury (mTBI), post-traumatic stress disorder (PTSD), and complex pain, with the goal of developing novel unobtrusive estimators of Sympathetic Activation of the Autonomic Nervous System (SAANS). In this study, we investigate whether heart rate variability (HRV) features extracted from electrocardiogram (ECG) measurements are correlated with clinical estimates of patient SAANS. Although previous studies have shown such correlation, the minimum amount of ECG data typically required for HRV feature extraction preclude their application in the present study; SAANS is expected to change quickly during therapy sessions and a rapid estimator is required. This paper investigates the use of ultra-short-term features extracted from ECG measurements for SAANS estimation with data collected during rehabilitation sessions with a Computer-Assisted Rehabilitation Environment (CAREN). A comparison between different scores and time excerpts were analysed using a single patient (n=1), over fifteen sessions, and sixty-seven activities. Preliminary results show that there was a significant difference between the AFTER and START excerpts (p = 0.045) for the meanNN feature, and between score \"four\" to scores \"zero\" (p = 0.01), and \"three\" (p = 0.02) for the stdNN feature.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114810477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Andreozzi, M. A. Pirozzi, A. Fratini, G. Cesarelli, P. Bifulco
{"title":"Quantitative performance comparison of derivative operators for intervertebral kinematics analysis","authors":"E. Andreozzi, M. A. Pirozzi, A. Fratini, G. Cesarelli, P. Bifulco","doi":"10.1109/MeMeA49120.2020.9137322","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137322","url":null,"abstract":"Comparison of derivative operators via quantitative performance analysis is rarely addressed in medical imaging. Indeed, the main application of such operators is the extraction of edges and, since there is no unequivocal definition of edges, the common trend is to identify the best performing operator based on a qualitative match between the extracted edges and the fickle human perception of object boundaries. This study presents an objective comparison of four first-order derivative operators through quantitative analysis of results yielded in a specific task, i.e. a spine kinematics application. Such application is based on a template matching method, which estimates common kinematic parameters of intervertebral segments from an X-ray fluoroscopy sequence of spine motion, by operating on the image derivatives of each frame. Therefore, differences in image derivatives, computed via different derivative operators, may lead to differences in estimated parameters of intervertebral kinematics. The comparison presented in this study focused on the trajectory of the instantaneous center of rotation (ICR) of an intervertebral segment, as it is particularly sensitive even to very small differences in displacements and velocities. Therefore, a quantitative analysis of the discrepancies between the ICR trajectories, obtained with each of the four considered derivative operators, was carried out by defining quantitative measures. The results showed detectable differences in the obtained ICR trajectories, thus highlighting the need for quantitative analysis of derivative operator performances in applications aimed at providing quantitative results. However, the significance level of such differences for clinical applications should be further assessed, but, currently, it is not possible, as there is no consensus and sufficient data on kinematic parameters features associated with specific spinal pathologies.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121750967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emanuela Allegretti, Elena Sibilano, A. Nisio, A. Lanzolla, M. Spadavecchia
{"title":"Assessment and Calibration of Wearable Heart Rate Sensors Using a Fully Automated System","authors":"Emanuela Allegretti, Elena Sibilano, A. Nisio, A. Lanzolla, M. Spadavecchia","doi":"10.1109/MeMeA49120.2020.9137329","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137329","url":null,"abstract":"Heart Rate (HR) monitors have become pervasive tools, with a great impact on fitness as well as on healthcare. The development of smart wearable systems to monitor physiological parameters addresses the need to manage real-time data for both personal and medical needs. Therefore, it is fundamental to assess and improve the reliability of these devices in HR measurement. The objective of this study was to evaluate the overall performance of a commercial chest-strap HR monitor and perform a calibration procedure. A DAQ-based system was developed to acquire and process raw signals from the sensor. When tested using a highly stable generated ECG signal, the device showed very small measurements errors with low standard deviation, granting high accuracy and good performance that improved even more after calibrating it.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132297532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MeMeA 2020 Author Index","authors":"","doi":"10.1109/memea49120.2020.9137112","DOIUrl":"https://doi.org/10.1109/memea49120.2020.9137112","url":null,"abstract":"","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130248013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Gullino, S. Grassini, E. Angelini, E. Padovano, C. Badini, L. Iannucci, M. Parvis
{"title":"Electrochemical behaviour of additively manufactured titanium for biomedical applications","authors":"A. Gullino, S. Grassini, E. Angelini, E. Padovano, C. Badini, L. Iannucci, M. Parvis","doi":"10.1109/MeMeA49120.2020.9137205","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137205","url":null,"abstract":"Commercially pure titanium is an important material for several biomedical applications, thanks to its capability to promote osseointegration and its mechanical properties. In recent years, new processing routes like additive manufacturing have opened new frontiers in the exploitation of this material in the biomedical field, giving the possibility to realize new shapes and decrease the overall weight of the prostheses. At the same time, due to these new forming technologies, new issues are faced, like the presence of a fine microstructure and the relation between porosity in the final component and the process parameters. This paper employs electrochemical measurements to assess the porosity effect on the corrosion behaviour of additively manufactured titanium in simulated body fluids. Specifically, the possibility of assessing different porosity levels related to processing parameters change is discussed.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133896926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Machine Learning Based Hardware Model for a Biomedical System for Prediction of Respiratory Failure","authors":"Omiya Hassan, S. Shamsir, S. Islam","doi":"10.1109/MeMeA49120.2020.9137291","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137291","url":null,"abstract":"This paper proposes a hardware design model of a machine learning based fully connected neural network for detection of respiratory failure among neonates in the Neonatal Intensive Care Unit (NICU). The model has been developed for a diagnostic system comprised of pyroelectric transducer based breathing monitor and a pulse oximeter that can detect apneic events. The input signal of the proposed system is a digitally converted sensory data from the sensors which is processed using machine learning model to detect if apnea condition has occurred in the patient. The accuracy rate of the proposed model is around 99 percent. The proposed design methodology enables the simplification of the models for future low-cost neural network- on-chip hardware implementation.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130840257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Caporaso, A. Palomba, S. Grazioso, D. Panariello, G. Gironimo, F. Gimigliano, G. Iolascon, A. Lanzotti
{"title":"Development of site–specific biomechanical indices for estimating injury risk in cycling","authors":"T. Caporaso, A. Palomba, S. Grazioso, D. Panariello, G. Gironimo, F. Gimigliano, G. Iolascon, A. Lanzotti","doi":"10.1109/MeMeA49120.2020.9137327","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137327","url":null,"abstract":"In this paper we present novel biomechanical indices for site–specific assessment of injury risk in cycling. The indices are built from a multifactorial analysis based on the kinematics and kinetics of the cyclist from the biomechanical side, and muscle excitations and muscle synergies from the neurophysiological side. The indices are specifics for three body regions (back, knee, ankle) which are strongly affected by overuse injuries in cycling. We use these indices for injury risks analysis of a recreational cyclist, who offered to participate in the experiments. The preliminary results are promising towards the use of such indices for planning and/or evaluating training schedule with the final goal of reducing non–traumatic injuries in cycling.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"5 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128820445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Manual and Automated Pressure Calibration Methods of Medical Pressure Calibrator","authors":"A. Türk, A. Hamarat, B. Karaböce","doi":"10.1109/MeMeA49120.2020.9137288","DOIUrl":"https://doi.org/10.1109/MeMeA49120.2020.9137288","url":null,"abstract":"In this study, manual calibration method of medical pressure calibrator is compared against automated one. Comprehensive calibration method in the Euramet cg-17 guide is followed for both manual and automated calibrations. Normalized error value (En) is used to compare equivalence of methods. En values show that manual and automated pressure calibrations are equivalent to each other. However, uncertainty values obtained at automated calibration are lower than ones obtained at manual calibration. Reasons for higher uncertainty in manual calibration are higher repeatability and higher zero deviation values. Hysteresis values are comparable to each other. In addition, two different digital manometers having different measurement principles were used as reference instruments in order to exhibit the effect of changing atmospheric pressure on gauge pressure measurements. Calibration results showed that it is necessary to take into consideration atmospheric pressure changes at gauge pressure calibrations for lower uncertainty.","PeriodicalId":152478,"journal":{"name":"2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"123 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133808969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}