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Journal of Applied Pharmacy最新文献

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Development and Clinical Application of Highly Bioavailable Curcumin (Theracurmin) 高生物利用度姜黄素(Theracurmin)的研制及临床应用
Journal of Applied Pharmacy Pub Date : 2021-01-01 DOI: 10.35248/1920-4159.21.13.303
B. Sanila
{"title":"Development and Clinical Application of Highly Bioavailable Curcumin (Theracurmin)","authors":"B. Sanila","doi":"10.35248/1920-4159.21.13.303","DOIUrl":"https://doi.org/10.35248/1920-4159.21.13.303","url":null,"abstract":"","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"3 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85147412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Note On Development of a Survey Tool to Measuring Vaccine Hesitancy 关于开发一种测量疫苗犹豫度的调查工具的编辑说明
Journal of Applied Pharmacy Pub Date : 2021-01-01 DOI: 10.35248/1920-4159.21.13.296
S. Lakshmi
{"title":"Editorial Note On Development of a Survey Tool to Measuring Vaccine Hesitancy","authors":"S. Lakshmi","doi":"10.35248/1920-4159.21.13.296","DOIUrl":"https://doi.org/10.35248/1920-4159.21.13.296","url":null,"abstract":"","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"47 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91208425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MULTIDRUG-RESISTANT TUBERCULOSIS AMONG CHILDREN UNDER 15 YEARS OF AGE IN KHYBER PAKHTUNKHWA PROVINCE AND FEDERALLY ADMINISTERED TRIBAL AREAS PAKISTAN 巴基斯坦开伯尔-普赫图赫瓦省和联邦直辖部落地区15岁以下儿童的耐多药结核病
Journal of Applied Pharmacy Pub Date : 2020-12-27 DOI: 10.21065/19204159.12.82
Ayesha Farooq, Fazal Noor Ume Sughra, Taha Nazir
{"title":"MULTIDRUG-RESISTANT TUBERCULOSIS AMONG CHILDREN UNDER 15 YEARS OF AGE IN KHYBER PAKHTUNKHWA PROVINCE AND FEDERALLY ADMINISTERED TRIBAL AREAS PAKISTAN","authors":"Ayesha Farooq, Fazal Noor Ume Sughra, Taha Nazir","doi":"10.21065/19204159.12.82","DOIUrl":"https://doi.org/10.21065/19204159.12.82","url":null,"abstract":"Tuberculosis is re-emerging in the form of drug resistant causing deaths of humans throughout the world. In 2015, WHO estimates, this disease developed in 10.4 million and causes death in 1.8 million human population. Moreover, new challenges like TB/HIV co-infection, MDR-TB is resisting to the preventive measures for controlling TB worldwide","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"20 4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83287759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PREVALENCE OF ANTIBIOTIC RESISTANCE AND ITS CHALLENGES FOR HEALTH CARE PROVIDERS 抗生素耐药性的流行及其对卫生保健提供者的挑战
Journal of Applied Pharmacy Pub Date : 2020-12-12 DOI: 10.21065/19204159.12.69
Saad bin Nawaz Noor-ul-Ain, Madiha Mustafa
{"title":"PREVALENCE OF ANTIBIOTIC RESISTANCE AND ITS CHALLENGES FOR HEALTH CARE PROVIDERS","authors":"Saad bin Nawaz Noor-ul-Ain, Madiha Mustafa","doi":"10.21065/19204159.12.69","DOIUrl":"https://doi.org/10.21065/19204159.12.69","url":null,"abstract":"The load of antibiotic resistance has been prevailing worldwide which is deteriorating health and human development. Antibiotics also called antimicrobial are the wonder drugs used to act against the microbes.","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91314412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ANTICANCER ACTIVITIES OF CHITOSAN AND CHITOSAN NANOPARTICLES AGAINST SOME CANCEROUS CELL LINES 壳聚糖及壳聚糖纳米颗粒对某些癌细胞的抗癌作用
Journal of Applied Pharmacy Pub Date : 2020-07-20 DOI: 10.21065/19204159.12.1
T. Aly, M. F. Ali, Fayed Koutb, Cunshan Zhou, Sayed A. Fayed, Emam A. ELRahim, Xiaojie Yu
{"title":"ANTICANCER ACTIVITIES OF CHITOSAN AND CHITOSAN NANOPARTICLES AGAINST SOME CANCEROUS CELL LINES","authors":"T. Aly, M. F. Ali, Fayed Koutb, Cunshan Zhou, Sayed A. Fayed, Emam A. ELRahim, Xiaojie Yu","doi":"10.21065/19204159.12.1","DOIUrl":"https://doi.org/10.21065/19204159.12.1","url":null,"abstract":"Cancer is considering a major leading cause of mortality. Nanotechnology holds a gold promise to develop cancer drug delivery and treatment. The present study aimed to compare in-vitro anticancer activities of chitosan (CS) and chitosan nanoparticles (CSN) against MCF7, PC3, HCT116 and A549 cell lines. The nanoparticles physic-chemical properties were estimated by Transmission Electron Microscopy (TEM) and Fourier Transform Infrared analysis (FTIR) through size and zeta potential analysis. In the current study, the results revealed that, the average diameter and zeta potential of CSN were 116.5 nm and 6.43 mV, respectively. Subsequently, CSN showed the anticancer activity with the LC50 values of 101.28 I¼g/mL in MCF7, 367.65 I¼g/mL in PC3, 666.67 I¼g/mL in HCT116 and 681.82 I¼g/mL in A549, whereas CS gave the LC50 values of 102.67 I¼g/mL in MCF7, 694.44 I¼g/mL in PC3, 1470.59 I¼g/mL in HCT116 and 769.23 I¼g/mL in A549. This study concluded that CSN were better than those obtained from CS as anticancer agent","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"18 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83686167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Study to Determine the Effects of Aceclofenac Sodium on Angiogenesis by using Chorioallantoic Membrane (CAM) Assay 用绒毛膜法测定乙酰氯芬酸钠对血管生成的影响
Journal of Applied Pharmacy Pub Date : 2020-01-01 DOI: 10.35248/2376-0354.20.12.271
Anam Nazeer, Lubna Shakir, Z. Rehman, Owais Omer, K. Najam, Mohsan Sohail, Nasira Saeed, Tayyaba Nazir, S. Aslam, Arshia Batool Khanum
{"title":"A Study to Determine the Effects of Aceclofenac Sodium on Angiogenesis by using Chorioallantoic Membrane (CAM) Assay","authors":"Anam Nazeer, Lubna Shakir, Z. Rehman, Owais Omer, K. Najam, Mohsan Sohail, Nasira Saeed, Tayyaba Nazir, S. Aslam, Arshia Batool Khanum","doi":"10.35248/2376-0354.20.12.271","DOIUrl":"https://doi.org/10.35248/2376-0354.20.12.271","url":null,"abstract":"The chick Chorioallantoic Membrane (CAM) is a possibly three-dimensional representation that can be used for in vivo as well as in situ studies. Its relatively easily available, relatively less expensive and consistent in quality render it an appropriate biological model for the use in experiments requiring live tissues. The aim of current research was to determine the angiogenic/antiangiogenic effect of Aceclofenac Sodium (AcS) and the effective dose of AcS. Total 30 fertilized chicken eggs (5 days old) were obtained from a Big bird Pvt. Ltd (local hatchery). Five groups were formed. They were incubated at 37°C with humidity of 55-60%. An opening about 2 cm of diameter was created under aseptic conditions by removing the shell and inner shell membrane. On 6thday of fertilization, Group A was given 0.1 ml Phosphate Buffer Saline (PBS) and served as control, group B, C, D and E were given 0.64 mg/0.1 ml, 0.32 mg/0.1 ml, 0.16 mg/0.1 ml, and 0.08 mg/0.1 ml of AcS respectively. Eggs were then again sealed with paraffin film under sterile environment and were kept in incubator for next 24 hours. After incubation period, the CAM was exposed and pictures were taken. The growth of blood vessels, diameter, branching pattern, surface roughness and other characteristics were evaluated by using Adobe Photoshop and Scan Probing Image Processing (SPIP). AsS showed dose dependent dual effect. At low concentration (0.08 mg/ml) it showed anti-angiogenic effect whereas at higher concentration (0.64 mg/ml) it produced angiogenic results. This indicates that AsS can be beneficial for development of strategies for prevention and therapy for several types of angiogenesis dependent diseases.","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"25 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74278078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolic Profiling of Eclipta prostrata L.: Potentials of Untargeted Metabolomics 黄竹的代谢谱分析:非靶向代谢组学的潜力
Journal of Applied Pharmacy Pub Date : 2020-01-01 DOI: 10.35248/2376-0354.20.12.274
Untargeted metabolomics, Lc-Ms analysis, Gc-Ms analysis, L. Ecliptaprostrata
{"title":"Metabolic Profiling of Eclipta prostrata L.: Potentials of Untargeted Metabolomics","authors":"Untargeted metabolomics, Lc-Ms analysis, Gc-Ms analysis, L. Ecliptaprostrata","doi":"10.35248/2376-0354.20.12.274","DOIUrl":"https://doi.org/10.35248/2376-0354.20.12.274","url":null,"abstract":"We have demonstrated the use of untargeted metabolomics- a high-throughput analysis to probe the small molecule landscape of natural products based traditional medicine. The approach provides a global perspective on the quality of such natural medicine and the depth of secondary metabolites present in them. We utilized Eclipta prostrata L. as an example to demonstrate the utility of LC-MS and GC-MS based untargeted metabolomics. The mentioned research utilized three different preparations and successfully demonstrated the small molecule landscape differences in these samples. Preliminary statistical analysis using R-based web programs, indicated the samples grouped well indicating batch-to-batch consistency. Heatmaps generated from LC-MS and GC-MS data indicated the difference in abundance of various small molecules across the samples.","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"14 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74467842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE EFFECT OF ANTIBIOTIC /ANTISEPTIC COMBINATION ON PROPIONIBACTERIUM ACNES TO OVERCOME ANTIBIOTIC RESISTANCE. THE EFFECT OF ANTIBIOTIC /ANTISEPTIC COMBINATION ON PROPIONIBACTERIUM ACNES TO OVERCOME ANTIBIOTIC RESISTANCE. 抗生素/抗菌剂联合应用对痤疮丙酸杆菌耐药的影响。抗生素/抗菌剂联合应用对痤疮丙酸杆菌耐药的影响。
Journal of Applied Pharmacy Pub Date : 2020-01-01 DOI: 10.21065/19204159.12.57
Rehab A Abbas
{"title":"THE EFFECT OF ANTIBIOTIC /ANTISEPTIC COMBINATION ON PROPIONIBACTERIUM ACNES TO OVERCOME ANTIBIOTIC RESISTANCE. THE EFFECT OF ANTIBIOTIC /ANTISEPTIC COMBINATION ON PROPIONIBACTERIUM ACNES TO OVERCOME ANTIBIOTIC RESISTANCE.","authors":"Rehab A Abbas","doi":"10.21065/19204159.12.57","DOIUrl":"https://doi.org/10.21065/19204159.12.57","url":null,"abstract":"Acne vulgaris has been treated usually with antibiotics. Propionibacterium acnes (P. acnes) play a crucial role in its pathogenesis, however, P. acnes has been described to develop antibiotic resistance.","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79763158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DISSOLUTION PROFILE OF METRONIDAZOLE TABLET IN DIVERSE FATTY DISSOLUTION MEDIUMS. 甲硝唑片在不同脂肪溶出介质中的溶出度。
Journal of Applied Pharmacy Pub Date : 2020-01-01 DOI: 10.21065/19204159.12.19
Amber Nawab
{"title":"DISSOLUTION PROFILE OF METRONIDAZOLE TABLET IN DIVERSE FATTY DISSOLUTION MEDIUMS.","authors":"Amber Nawab","doi":"10.21065/19204159.12.19","DOIUrl":"https://doi.org/10.21065/19204159.12.19","url":null,"abstract":"","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73864949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmaceutical forms and Drug-disease Interaction: An Old-new Case 药物形态与药物-疾病相互作用:一个新旧案例
Journal of Applied Pharmacy Pub Date : 2020-01-01 DOI: 10.35248/2376-0354.20.12.275
N. Al-Somai
{"title":"Pharmaceutical forms and Drug-disease Interaction: An Old-new Case","authors":"N. Al-Somai","doi":"10.35248/2376-0354.20.12.275","DOIUrl":"https://doi.org/10.35248/2376-0354.20.12.275","url":null,"abstract":"Theophylline is a drug that has been used for asthma disease, for more than 80 years. It has been used for its bronchodilator effects; however, dosing was critical because of it is narrow therapeutic index which may lead to failure in treatment of toxicity. This case illustrates the important of individualization of the theophylline based on the patient medical history. Pharmacist intervention and knowledge in the drug disease interaction, considering the pharmacokinetics data, would be valuable for the success of the treatment","PeriodicalId":15238,"journal":{"name":"Journal of Applied Pharmacy","volume":"13 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82524166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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