{"title":"Artificial-intelligence-enhanced ECG: a potential solution to limitations of ECG in detecting left ventricular dysfunction after chemotherapy.","authors":"Hong-Mi Choi, Youngjin Cho","doi":"10.2459/JCM.0000000000001725","DOIUrl":"https://doi.org/10.2459/JCM.0000000000001725","url":null,"abstract":"","PeriodicalId":15228,"journal":{"name":"Journal of Cardiovascular Medicine","volume":"26 5","pages":"224-226"},"PeriodicalIF":2.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"News from American College of Cardiology Congress: Chicago 2025.","authors":"Domenico Simone Castiello, Ciro Indolfi","doi":"10.2459/JCM.0000000000001726","DOIUrl":"https://doi.org/10.2459/JCM.0000000000001726","url":null,"abstract":"","PeriodicalId":15228,"journal":{"name":"Journal of Cardiovascular Medicine","volume":"26 5","pages":"195-199"},"PeriodicalIF":2.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The relevance of Killip class in ST-segment elevation myocardial infarction patients: implications on treatment timing and in-hospital mortality.","authors":"Valentina Bernardini, Davide Cao, Giulio Stefanini","doi":"10.2459/JCM.0000000000001720","DOIUrl":"https://doi.org/10.2459/JCM.0000000000001720","url":null,"abstract":"","PeriodicalId":15228,"journal":{"name":"Journal of Cardiovascular Medicine","volume":"26 5","pages":"248-250"},"PeriodicalIF":2.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rachele Manzo, Giuseppe Comentale, Federica Ilardi, Anna Franzone, Emanuele Pilato, Giovanni Esposito
{"title":"Mitral-aortic intervalvular fibrosa pseudoaneurysm: a sneaky complication mimicking early prosthesis degeneration.","authors":"Rachele Manzo, Giuseppe Comentale, Federica Ilardi, Anna Franzone, Emanuele Pilato, Giovanni Esposito","doi":"10.2459/JCM.0000000000001721","DOIUrl":"https://doi.org/10.2459/JCM.0000000000001721","url":null,"abstract":"","PeriodicalId":15228,"journal":{"name":"Journal of Cardiovascular Medicine","volume":"26 5","pages":"251-252"},"PeriodicalIF":2.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Irene Borzillo, Fabrizio D Ascenzo, Emanuele Ravetti, Marco Balducci, Riccardo Pilia, Matteo Michelone, Giuseppe Annoni, Alessandra Toscano, Giuseppe Giannino, Gaetano Maria De Ferrari, Ovidio De Filippo
{"title":"Lipoprotein(a) in youth and childhood as a marker of cardiovascular risk stratification: a meta-analysis.","authors":"Irene Borzillo, Fabrizio D Ascenzo, Emanuele Ravetti, Marco Balducci, Riccardo Pilia, Matteo Michelone, Giuseppe Annoni, Alessandra Toscano, Giuseppe Giannino, Gaetano Maria De Ferrari, Ovidio De Filippo","doi":"10.2459/JCM.0000000000001718","DOIUrl":"https://doi.org/10.2459/JCM.0000000000001718","url":null,"abstract":"<p><strong>Background and aims: </strong>Lipoprotein(a) [Lp(a)] is recognized as a risk factor for atherosclerotic cardiovascular diseases (ASCVD), yet its impact during childhood and youth remains understudied. This study aims to evaluate the role of Lp(a) as an independent risk factor for premature ASCVD among young patients.</p><p><strong>Methods: </strong>PubMed, Scopus, and CINAHL Complete databases were systematically searched from inception to 12 December 2023 for adjusted observational studies examining the impact of Lp(a) in young patients. Premature coronary artery disease (CAD) and premature arterial stroke were designed as primary endpoints, while the association with family history of premature CAD and familial hypercholesterolemia were secondary endpoints.</p><p><strong>Results: </strong>Fourteen studies, encompassing 9923 patients, were included in the analysis. Nine studies assessed Lp(a) as an independent risk factor for premature CAD. Meta-analysis revealed Lp(a) to be significantly associated with premature CAD [odds ratio (OR) 1.07, 95% confidence interval (CI) 1.01-1.13, P = 0.02]. Four studies revealed that the high levels of Lp(a) were associated with a more than two-fold increased risk of arterial stroke (OR 2.51; 95% CI 1.51-4.16, P = 0.004). However, insufficient studies were retrieved to perform a metanalysis for the secondary endpoints.</p><p><strong>Conclusion: </strong>Findings from adjusted observational studies suggest that Lp(a) serves as a risk factor for premature CAD and for arterial stroke in the youngest population.</p>","PeriodicalId":15228,"journal":{"name":"Journal of Cardiovascular Medicine","volume":"26 5","pages":"227-234"},"PeriodicalIF":2.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Looking for lipoprotein(a) in youngsters: a call to action.","authors":"Claudio Bilato, Marco Zuin, Gianluca Rigatelli","doi":"10.2459/JCM.0000000000001717","DOIUrl":"https://doi.org/10.2459/JCM.0000000000001717","url":null,"abstract":"","PeriodicalId":15228,"journal":{"name":"Journal of Cardiovascular Medicine","volume":"26 5","pages":"235-239"},"PeriodicalIF":2.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is catheter ablation the first line treatment of ventricular tachycardia after myocardial infarction?","authors":"Antonio Curcio, Antonio Frontera, Michela Casella","doi":"10.2459/JCM.0000000000001712","DOIUrl":"10.2459/JCM.0000000000001712","url":null,"abstract":"","PeriodicalId":15228,"journal":{"name":"Journal of Cardiovascular Medicine","volume":" ","pages":"169-171"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anastase Dzudie, Benyass Aatif, Lambert T Appiah, Habib Gamra, Mouhamed Cherif Mboup, Redouane Nedjar, Roland N'Guetta, Mohamed Jeilan, Okechukwu S Ogah, Fausto Pinto, Zainab Raissouni, Giuseppe M C Rosano
{"title":"Chronic coronary syndrome in Africa: current management and service challenges, and opportunities for optimizing patient care.","authors":"Anastase Dzudie, Benyass Aatif, Lambert T Appiah, Habib Gamra, Mouhamed Cherif Mboup, Redouane Nedjar, Roland N'Guetta, Mohamed Jeilan, Okechukwu S Ogah, Fausto Pinto, Zainab Raissouni, Giuseppe M C Rosano","doi":"10.2459/JCM.0000000000001707","DOIUrl":"10.2459/JCM.0000000000001707","url":null,"abstract":"<p><p>African populations have traditionally been considered at relatively low risk of cardiovascular diseases (CVD), such as chronic coronary syndrome (CCS), but this is rapidly changing in association with ageing populations, uncontrolled urbanization and lack of control of classical CV risk factors. In sub-Saharan Africa, CVD deaths have increased by more than 50% in the past three decades. For CCS care, limited availability of clinical expertise, diagnostic facilities, and access to optimal medical therapy (OMT), lack or inadequate reimbursement of healthcare costs, and scarcity of universal health coverage (UHC) are major challenges. Cardiologists from 11 African countries, meeting through the AFEX: ACT ON Angina programme, with the endorsement of the World Heart Federation, identified the need to: engage clinicians, patients, and the media to raise awareness of CCS and angina, and encourage lifestyle modification and risk factor control, as well as early referral of high-risk individuals; develop care pathways to address growing demand, including cross-border and online collaboration where local expertise is unavailable; optimize the use of treatment budgets by adapting and implementing international guidelines according to local priorities, and avoiding prescription of nonevidence-based medicines; initiate collaborative research into the nature of CCS in African countries and potential differences in risk factors, presentation, and treatment response compared with Europe and North America whose experience forms the basis of international guidelines. A roadmap is proposed to guide future developments in CCS care and support best practices across Africa.</p>","PeriodicalId":15228,"journal":{"name":"Journal of Cardiovascular Medicine","volume":"26 4","pages":"172-181"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143575863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luca Fazzini, Alessandro Martis, Maria Ida Pateri, Alessandra Maccabeo, Giuseppe Borghero, Monica Puligheddu, Roberta Montisci, Maria Francesca Marchetti
{"title":"Long-term outcomes and worse clinical course in Takotsubo syndrome patients with amyotrophic lateral sclerosis.","authors":"Luca Fazzini, Alessandro Martis, Maria Ida Pateri, Alessandra Maccabeo, Giuseppe Borghero, Monica Puligheddu, Roberta Montisci, Maria Francesca Marchetti","doi":"10.2459/JCM.0000000000001711","DOIUrl":"10.2459/JCM.0000000000001711","url":null,"abstract":"<p><strong>Aims: </strong>Takotsubo syndrome (TTS) is usually triggered by either physical/psychological stressors or comorbidities, neurological among others. The prevalence of amyotrophic lateral sclerosis (ALS) among TTS and whether it has a worse clinical course is not known. We aim to describe ALS prevalence and its impact on clinical presentation, clinical course, and long-term mortality.</p><p><strong>Methods: </strong>We retrospectively screened the overall TTS population admitted and followed up at our institution between 2007 and 2020. Clinical, electrocardiographic, and echocardiographic data were collected. Kaplan-Meier method was applied for time-to-event analysis to assess the outcome of interest of all-cause death.</p><p><strong>Results: </strong>Eighty-five patients with TTS were included in our study. Overall, the mean age was 70 ± 12 years, 86% were females. Six patients (7% prevalence) were affected by ALS. At admission, patients with ALS were more likely to present left ventricular systolic dysfunction (P = 0.007). The clinical course of ALS patients was more likely complicated by cardiogenic shock (P = 0.003) which required catecholamines infusion (P = 0.001) and mechanical ventilation (P = 0.009). Despite similar in-hospital mortality rates, ALS patients exhibited significantly elevated all-cause mortality during a median 6-year follow-up (hazard ratio, 19.189, 95% confidence interval 5.639-65.296, log-rank test P < 0.001) with significantly shorter hospitalization to death time (P = 0.039).</p><p><strong>Conclusions: </strong>Our findings highlight a notable prevalence of ALS among TTS patients, with worse clinical presentation and in-hospital course in ALS-affected individuals. While in-hospital mortality rates were comparable, highlighting the reversible nature of TTS in both groups, long-term follow-up revealed significantly heightened all-cause mortality in ALS patients, emphasizing the impact of ALS on patient prognosis.</p>","PeriodicalId":15228,"journal":{"name":"Journal of Cardiovascular Medicine","volume":"26 4","pages":"184-190"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143575876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}